DanielDavidBikleMD

PubMed

• 2 citations
  Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics.
  Roman Thaler, Keigo Yoshizaki, Thai Nguyen, Satoshi Fukumoto, Pamela Den Besten, Daniel D Bikle, Yuko Oda> ;Communications Biology. 2023 Jul 21
• Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate.
  Yuko Oda, Christian T Wong, Dennis H Oh, Mark B Meyer, J Wesley Pike, Daniel D Bikle> ;The Journal of Steroid Biochemistry and Molecular Biology. 2023 Sep 1
• 1 citations
  Highlights from the 24th workshop on vitamin D in Austin, September 2022.
  Mark B Meyer, Carlos Bernal-Mizrachi, Daniel D Bikle, Madhu Biyani, Moray J Campbell, Snehal N Chaudhari, Sylvia Christakos, Sue A Ingles, Megan M Knuth, Seong Min Lee...> ;The Journal of Steroid Biochemistry and Molecular Biology. 2023 Apr 1
• 1 citations
  Prevalence of osteoporosis in older male veterans receiving hip-containing computed tomography scans: opportunistic use of biomechanical computed tomography analysis (...
  Polly F Teng, Janet M Chiang, Anne L Schafer, Preeti A Sukerkar, Tony M Keaveny, Daniel Bikle> ;Osteoporosis International. 2023 Mar 1
• 1 citations
  Skin and bone crosstalk during aging.
  Theodora Mauro, Daniel Bikle> ;Nature Aging. 2022 Oct 1
• Response to Letters to the Editor RE: Association of Vitamin D Status and COVID-19-Related Hospitalization and Mortality.
  Karen H Seal, Daniel Bertenthal, Daniel D Bikle> ;Journal of General Internal Medicine. 2022 Oct 1
• 20 citations
  Vitamin D Regulation of Immune Function.
  Daniel D Bikle> ;Current Osteoporosis Reports. 2022 Jun 1
• 19 citations
  Vitamin D regulation of immune function during covid-19.
  Daniel D Bikle> ;Reviews in Endocrine & Metabolic Disorders. 2022 Apr 1
• 7 citations
  Ligand-Independent Actions of the Vitamin D Receptor: More Questions Than Answers
  Daniel D. Bikle> ;JBMR Plus. 2021 Nov 23
• 2 citations
  Hypercalcemia in non-Hodgkin's lymphoma due to cosecretion of PTHrP and 1,25-dihydroxyvitamin D.
  A R Gonciulea, Y Wang, Daniel D. Bikle, Deborah E. Sellmeyer> ;Osteoporosis International. 2021 Jul 6
• 9 citations
  Vitamin D regulation of and by long non coding RNAs.
  Daniel D. Bikle> ;Molecular and Cellular Endocrinology. 2021 May 17
• 10 citations
  Decreased Calcium-Sensing Receptor Expression Controls Calcium Signaling and Cell-To-Cell Adhesion Defects in Aged Skin.
  Anna Celli, Chia-Ling Tu, Elise Lee, Daniel D. Bikle, Theodora M. Mauro> ;The Journal of Investigative Dermatology. 2021 Nov 1
• 40 citations
  The Free Hormone Hypothesis: When, Why, and How to Measure the Free Hormone Levels to Assess Vitamin D, Thyroid, Sex Hormone, and Cortisol Status
  Daniel D. Bikle> ;JBMR Plus. 2021 Jan 1
• 2 citations
  Introduction: Special Issue on Vitamin D Dedicated to the Memory of Anthony W Norman
  Roger Bouillon, Mark R. Haussler, Daniel D. Bikle, Sylvia Christakos, JoEllen Welsh> ;JBMR Plus. 2021 Jan 1
• 3 citations
  Ablation of Ephrin B2 in Col2 Expressing Cells Delays Fracture Repair.
  Yongmei Wang, Lin Ling, Faming Tian, Sun Hee Won Kim, Sunita P. Ho, Daniel D. Bikle> ;Endocrinology. 2020 Dec 1
• 8 citations
  Transcriptional Regulation of Dental Epithelial Cell Fate.
  Keigo Yoshizaki, Satoshi Fukumoto, Daniel D. Bikle, Yuko Oda> ;International Journal of Molecular Sciences. 2020 Nov 25
• 196 citations
  MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19.
  John P. Bilezikian, Daniel D. Bikle, Martin Hewison, Marise Lazaretti-Castro, Anna Maria Formenti, Aakriti Gupta, Mahesh V. Madhavan, Nandini Nair, Varta Babalyan, Nic...> ;European Journal of Endocrinology. 2020 Nov 1
• 2 citations
  The Vitamin D Receptor as Tumor Suppressor in Skin.
  Daniel D Bikle> ;Advances in Experimental Medicine and Biology. 2020 Jan 1
• 3 citations
  Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration.
  Yuko Oda, Thai Nguyen, Akiko Hata, Mark B. Meyer, J. Wesley Pike, Daniel D. Bikle> ;Plos One. 2020 Aug 28
• 10 citations
  Vitamin D and calcium signaling in epidermal stem cells and their regeneration.
  Yuko Oda, Daniel D. Bikle> ;World Journal of Stem Cells. 2020 Jul 26
• 5 citations
  p120-catenin suppresses proliferation and tumor growth of oral squamous cell carcinoma via inhibiting nuclear phospholipase C-γ1 signaling.
  Lusha Li, Shangli Ji, Chandrama Shrestha, Yi Jiang, Liyan Liao, Feng Xu, Zhenming Liu, Daniel D. Bikle, Zhongjian Xie> ;Journal of Cellular Physiology. 2020 Apr 30
• 5 citations
  Editorial: Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions.
  Zhongjian Xie, Xiangbing Wang, Daniel D Bikle> ;Frontiers in Endocrinology. 2020 Jan 1
• 146 citations
  New aspects of vitamin D metabolism and action - addressing the skin as source and target.
  Daniel D. Bikle, Sylvia Christakos> ;Nature Reviews. Endocrinology. 2020 Feb 6
• 67 citations
  Vitamin D: Newer Concepts of Its Metabolism and Function at the Basic and Clinical Level.
  Daniel D. Bikle> ;Journal of the Endocrine Society. 2020 Feb 8
• 48 citations
  Vitamin D Metabolism Revised: Fall of Dogmas
  Roger Bouillon, Daniel D. Bikle> ;Journal of Bone and Mineral Research. 2019 Nov 1
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Journal Articles

• Skeletal and Extra-Skeletal Actions of Vitamin D: Current Evidence and Outstanding Questions  
  John Bilezikian, Daniel Bikle, Endocrine Reviews
• Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations  
  Jennifer Lai, Janice B Schwartz, Michael Holick, Eric Orwoll, Daniel Bikle, The Journal of Clinical Endocrinology and Metabolism
• Osteoblast extracellular Ca(2+)-sensing receptor regulates bone development, mineralization and turnover.  
  Dvorak-Ewell MM, Chen TH, Liang N, Garvey C, Liu B, Tu C, Chang W, Bikle DD, Shoback DM, J Bone Min Res
• Negative crosstalk between the calcium sensing receptor and the -catenin signaling systems in colonic epithelium.  
  Rey O, Chang W, Bikle D, Rozengurt N, Young SH and Rozengurt E, J Biol Chem
• SERCA2-controlled Ca2+-dependent keratinocyte adhesion and differentiation is mediated via the sphingolipid pathway: a therapeutic target for Darier’s Disease.  
  Celli A, Mackenzie DS, Zhai Y, Tu C-L, Bikle DD, Holleran WM, Uchida Y, Mauro TM, J Invest Dermatol
• Ablation of the calcium-sensing receptor in keratinocytes impairs epidermal differentiation and barrier function.  
  Tu C-L, Crumrine D, Man M-Q, Chang W, Elalieh H, You M, Elias PM, and Bikle DD, J Invest Dermatol
• Discovery of the First Irreversible Small Molecule Inhibitors of the Interaction between the Vitamin D Receptor and Coactivators.  
  Nandhikonda P, Lynt W, McCallum M, Ara T, Baranowski A, Yuan N, Pearson D, Bikle D, Guy R K, Arnold AL, J Med Chem
• PTH/PTHrP and Vitamin D control antimicrobial peptide expression and susceptibility to bacterial skin infection.  
  Muehleisen B, Bikle DD, Aguilera C, Douglas W. Burton DW, Sen GL, Deftos LJ, Gallo RL, Sci Transl Med
• Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading.  
  Kubota T, Elalieh HZ, Saless N, Fong C, Wang Y, Babey M, Cheng Z, Bikle DD, Acta Astronautica
• Differential response of duodenal epithelial cells to 1,25 dihydroxyvitamin D3 according to position on the villus: a comparison of calcium uptake, calcium binding pro...  
  Bikle DD, Zolock DT, Munson S, Endocrinology
• Microtubules and the migration of pigment in the melanophores of Fundulus heteroclitus L.  
  Bikle DD, Tilney L, Porter KR, Protoplasma
• Hormonal control of the renal conversion of 25 hydroxycholecalciferol to 1,25 dihydroxychole¬cal-cifer¬ol.  
  Rasmussen H, Wong M, Bikle D, Goodman DBP, J Clin Invest
• The metabolism of 25 hydroxycholecalciferol by iso¬lated renal tubules in vitro as studied by a new chromatographic tech¬nique.  
  Bikle DD, Rasmussen H, Biochim Biophys Acta
• A comparison of the metabolism of 25 hydroxy¬vitamin D3 by chick renal tubules, homogenates, and mitochondria.  
  Bikle DD, Rasmussen H, Biochim Biophys Acta
• The ionic control of 1,25 dihydroxyvitamin D3 pro¬duc¬tion in isolated chick renal tubules.  
  Bikle DD, Rasmussen H, J Clin Invest
• The ionic control of 1,25 dihydroxyvitamin D3 pro¬duc¬tion in isolated chick renal mitochondria: the role of calcium as influenced by inorganic phosphate and hydrogen ...  
  Bikle DD, Rasmussen H, J Clin Invest
• The ionic control of 1,25 di¬hydroxy¬vita¬min D3 synthesis in isolated chick renal mitochondria: the role of potassi¬um.  
  Bikle DD, Murphy EW, Rasmussen H, Biochim Biophys Acta
• The effect of 1,25 dihydroxyvitamin D3 on the distribution of alkaline phosphatase activity along the chick intestinal villus.  
  Bikle DD, Empson RN Jr, Herman RH, Morrissey RL, Zolock DT, Biochim Biophys Acta
• Ionic control of 1,25 dihydroxyvitamin D3 production by isolated chick renal mitochondria: influence of anions and sucrose.  
  Bikle DD, Rasmussen H, Biochim Biophys Acta
• Independence of 1,25 dihy¬droxy¬vitamin D3 mediated calcium transport from de novo RNA and protein synthe¬sis.  
  Bikle DD, Zolock DT, Morrissey RL, Herman RH, J Biol Chem
• A biochemical model for the ionic control of 25 hydroxy¬vi¬tamin D3 1 hydroxylase.  
  Bikle DD, Rasmussen H, J Biol Chem
• Intestinal re¬sponse to 1,25 dihydroxycholecalciferol. I. RNA polymerase, alkaline phospha¬tase, calcium and phosphorus uptake in vitro and in vivo calcium transport ...  
  Morrissey RL, Zolock DT, Bikle DD, Empson RN Jr, Bucci TJ, Biochim Biophys Acta
• Intestinal re¬sponse to 1,25 dihydroxycholecalciferol. II. A timed study of the intracellu¬¬lar localization of calcium binding protein.  
  Morrissey RL, Empson RN Jr, Zolock DT, Bikle DD, Bucci TJ, Biochim Biophys Acta
• Immunoperoxidase localization of vitamin D dependent calcium binding protein.  
  Morrissey RL, Zolock DT, Bucci TJ, Bikle DD, J Histochem Cytochem
• Work induced muscle hypertrophy in vitamin D deficient rats.  
  Bikle DD, Hagler L, Lollini LO, Hull SF, Herman RH, Am J Clin Nutr
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Books/Book Chapters

• Carafoli E. 
  Chapter: Calcium and nonvesicular secretion in the kidney: calcium and mitochondrial functions 
  Page 111 - 121Rasmussen H, Bikle DDEditors: Calcium Transport in Contrac¬tion and Secretion.North Holland Publishing Co
• Vitamin D: Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism. 
  Chapter: The dissociation of 1,25(OH)2D3 induced CaBP production and alkaline phosphatase activity from cal¬cium transport by actinomycin Dcontinuedandcycloh¬eximide 
  Page 223 - 225Bikle DD, Zolock DT, Morrissey RL, Herman RHEditors: Norman AW, Coburn JW, DeLuca HF, Fraser D, Grigoleit HG, Schaefer K.de Gruyter, Elmsford, NY
• Progress in HPLC. 
  Chapter: Use of HPLC and On line Radioactivity Monitoring in Studies o f Vitamin D Metabolism 
  Page 93 - 127Pillai S, Gee E, Bikle DDEditors: Reich A, Lucus-Reich S, Parvez S Binh Thanh: title: Progress in HPLC.Utrecht, International Science
• Quick Look Pharmacology. 
  Chapter: Drugs for altering calcium homeostasis: treatment of osteoporosis 
  Page 156 - 157Bikle DDEditors: RB Raffa.Fence Creek Publishing, Madison, CT
• Endotext.Org. 
  Chapter: Vitamin D: Production, Metabolism, and Mechanisms of Action 
  Bikle DDEditors: LJ DeGroot.
• ) Vitamin D: Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism. 
  Chapter: 1,25 dihydroxycholecalciferol stimulation of calcium binding protein specific m RNA 
  Page 227 - 229Charles MA, Martial J, Zolock D, Morrissey R, Bikle D, Baxter JEditors: Norman AW, Coburn JW, DeLuca HR, Fraser D, Grigoleit HG, Schaefer K.de Gruyter, Elmsford, NY
• Vitamin D: Bio¬chemical, Chemical and Clinical Aspects Related to Calcium Metabolism. 
  Chapter: The effect of 1,25 DHCC on the calcium accumulation, calcium transport, and calcium binding protein in the presence and absence of cycloheximide 
  Page 345 - 347Zolock DT, Morrissey RL, Bikle DDEditors: Norman AW, Coburn JW, DeLuca HF, Fraser D, Grigoleit HG, Schaefer K.de Gruyter, Elmsford, NY
• Vitamin D: Basic Research and its Clinical Applications. 
  Chapter: Meaning of nonparallel 1,25(OH)2D mediated response relationships in intestine and bone to dose and time 
  Page 639 - 642Zolock DT, Morrissey RL, Bikle DDEditors: Norman AW, Schaefer K, Herrath DV, Grigoleit HG, Coburn JW, DeLuca HF, Mawer EB, Suda T.de Gruyter, New York
• Vitamin D: Basic Research and its Clincial Applications. 
  Chapter: Is 1,24,25(OH)3D the principal intestinal metabolite in vitamin D repleted chicks? 
  Page 727 - 730Bikle DD, Morrissey RL, Zolock DT, Herman RHEditors: Norman AW, Schaefer K, Herrath DV, Grigoleit HG, Coburn JW, DeLuca HF, Mawer EB, Suda T.de Gruyter, New York
• Advances in Internal Medicine. 
  Chapter: The vitamin D endocrine system 
  Page 45 - 71Bikle DDEditors: Stollerman GH.Year Book Medical Publishers
• Vitamin D: Chemical, Biochemical, and Clinical Endocrinology of Calcium Metabolism. 
  Chapter: Calcium transport by chick duodenal brush border membrane vesi¬cles 
  Page 313 - 315Bikle DDEditors: Norman AW, Schaefer K, Herrath DV, Grigoleit HG.de Gruyter, New York
• Epithelial Calcium and Phosphate Transport: Molecular and Cellular Aspects. 
  Chapter: The role of calmodulin in 1,25 dihydroxyvitamin D regulation of calcium transport across the intestinal brush border membrane 
  Page 193 - 198Bikle DD, Munson S, Chafouleas JGEditors: Bronner F, Peterlik M.Liss, New York
• Endocrine Control of Bone and Calcium Metabolism. 
  Chapter: Calmodulin as a mediator of 1,25(OH)2D regulated intestinal calcium transport 
  Page 320 - 323Bikle DD, Chafouleas JGEditors: Cohn DV, Fujita T, Potts JT Jr, Talmage RV.Excerpta Medica, Amsterdam
• Alcohol induced bone disease in osteoporosis 1990. 
  Chapter: Handelstrykkeriet Aalborg 
  Page 1544 - 1551Bikle D, Stesin A, Halloran B, Steinbach L, Recker REditors: C Christiansen and K Overgaard.Denmark
• Vitamin D: Chemical, Biochemical and Clinical Update. 
  Chapter: Mechanisms by which 1,25 dihydroxyvitamin D regulates calmodulin binding to the duodenal brush border membrane 
  Page 393 - 395Bikle DD, Munson SJEditors: Norman AW, Schaefer K, Grigoleit HG, Herrath DV.Walter de Gruyter, New York
• Vitamin D: Chemical, Biochemical and Clinical Update. 
  Chapter: 1,25 dihydroxyvitamin D increases the in¬tracellular free calcium concentration of duodenal epithelial cells 
  Bikle DD, Shoback DM, Munson SJEditors: Norman AW, Schaefer K, Grigoleit HG, Herrath DV.Walter de Gruyter, New York
• ) Vitamin D: Molecular,Cellular,and Clinical Endocrinology. 
  Chapter: Measurement of free vitamin D metabolite levels: biological and clinical significance 
  Page 703 - 709Bikle DDEditors: Norman AW, Schaefer K, Grigoleit HG, Herrath DV.Walter de Gruyter, New York
• Vitamin D: Molecular, Cellular, and Clinical Endocrinology. 
  Chapter: The 105 kD calmodulin binding protein from intestinal brush border membrane (BBM) is a calcium transport protein 
  Page 577 - 578Bikle DD and Munson SEditors: Norman AW, Schaefer K, Grigoleit HG, Herrath DV.Walter de Gruyter, New York
• Vitamin D: Molecular, Cellular and Clinical Endocrinology. 
  Chapter: Accentuated transpleu¬ral gradient of "total" and "free" 1,25-dihyroxyvitamin D in patients with tuberculous pleuritis 
  Page 857 - 858Barnes PF, Modlin RL, Endres DB, Bikle DD, Adams JSEditors: Norman AW, Schaefer K, Grigoleit HG, Herrath DV.Walter de Gruyter, New York
• Vitamin D: Gene regulation, structure-function analysis and clinical application. 
  Chapter: Cloning and sequencing a vitamin D inducible protein from the intestine with an extensive leucine zipper motif and homology to tropomyo¬sin/myosin 
  Page 689 - 690Bikle DD, Munson S, Morrison N, Eisman JEditors: Norman AW, Bouillon R, Thomasset M.Walter de Gruyter, Berlin
• Vitamin D: Gene regulation, structure-function analysis and clinical application. 
  Chapter: Regulation of calmodulin binding to the ATP extractable 110k D protein from chicken duodenal brush border 
  Page 691 - 69227. Kaune R, Munson S, Bikle DDEditors: AW Norman, R Bouillon, M Thomasset.Walter de Gruyter, Berlin
• Vitamin D: Gene regulation, structure-function analysis and clinical application. 
  Chapter: Effects of 17 -estradiol and medroxyproge¬sterone on the serum concentration of 1,25-dihydroxyvitamin D in perimenopausal women 
  Page 845 - 84628. Halloran BP, Bikle DD, Harris ST, Portale AAEditors: AW Norman, R Bouillon, M Thomasset.Walter de Gruyter, Berlin
• Assay of Calcium regulating Hormones. 
  Bikle DDSpringer Verlag, New York
• Vitamin D, a pluripotent steroid hormone:structural studies,molecular endocrinology,and clinical applications. 
  Chapter: 1,25(OH)2D modulated calcium induced keratinocyte differentiation: from the culture dish to the psoriatic patient 
  Page 568 - 575Bikle DDEditors: AW Norman, R Bouillon, M Thomasset.pref Walter de Gruyter, Berlin (New York)
• Cecil Textbook of Medicine. 
  Chapter: Osteomalacia and rickets 
  Page 1425 - 1431Bikle DDEditors: Wyngaarden JB, Smith LH Jr, Plum F.Saunders, PhiladelphiaEdition 17th,
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Lectures

• Vitamin D. 
  Meeting report from the 26th Annual Meeting of the American Society fro Bone and Mineral Research