Antonio Abbate MD

Cardiology•Charlottesville, VA

Exercise Physiology and Cardiac Rehabilitation, Cardiac Critical Care

Professor of Medicine University of Virginia

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415 Lane RdCharlottesville, VA 22908
Phone+1 434-297-9449

Education & Training

Virginia Commonwealth University Health SystemResidency, Internal Medicine, 2004 - 2007
OtherClass of 2000

Certifications & Licensure

VA State Medical License 2004 - 2026
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Whos Who in Medicine and Healthcare Marquis Whos Who

Clinical Trials

Anakinra to Prevent Post-infarction Remodeling Start of enrollment: 2008 Nov 01
Completed
Phase 3
Anakinra to Prevent Adverse Post-infarction Remodeling (2) Start of enrollment: 2010 Jul 01
Completed
Phase 2
Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection Fraction Start of enrollment: 2012 Feb 01
Completed
Not Applicable
Interleukin-1 Blockade With Canakinumab to Improve Exercise Capacity in Patients With Chronic Systolic Heart Failure and Elevated High Sensitivity C-reactive Protein (Hs-CRP) Start of enrollment: 2013 Apr 01
Completed
Not Applicable
Alpha-1 Anti-Trypsin (AAT) Treatment in Acute Myocardial Infarction Start of enrollment: 2013 Dec 01
Completed
Phase 1, Phase 2
Interleukin-1 Blockade in Recently Decompensated Heart Failure Start of enrollment: 2014 Feb 01
Completed
Phase 2, Phase 3
Intestinal Ischemia as a Stimulus for Systemic Inflammatory Response After Cardiac Arrest Start of enrollment: 2013 Sep 01
Completed
Interleukin-1 (IL-1) Blockade in Acute Myocardial Infarction (VCU-ART3) Start of enrollment: 2014 Jul 01
Completed
Phase 2, Phase 3
Interleukin-1 Blockade in HF With Preserved EF Start of enrollment: 2014 Sep 01
Completed
Phase 2
Alirocumab in Patients With Acute Myocardial Infarction Start of enrollment: 2017 Jan 01
Completed
Phase 4
SP16 SERPIN-like Peptide Administration in Healthy Individuals Start of enrollment: 2018 Jul 16
Completed
Phase 1
Interleukin-1 Blockade In Recently Decompensated Heart Failure - 2 Start of enrollment: 2019 Jan 04
COMPLETED
PHASE2
Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis Start of enrollment: 2020 Oct 23
COMPLETED
PHASE2
SP16 Inflammatory Response Inhibition Trial Start of enrollment: 2020 Feb 24
Completed
Phase 1, Phase 2
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in Patients With Severe COVID-19 Pneumonia and Systemic Hyper-inflammation
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation Start of enrollment: 2020 Sep 02
Completed
Phase 2
Efficacy and Safety of RPH-104 Treatment in Patients With Recurrent Pericarditis
SUSPENDED
PHASE2, PHASE3
Roles: Contact
Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart Failure Start of enrollment: 2022 May 24
RECRUITING
PHASE2
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Current Drug Treatment for Acute and Recurrent Pericarditis.
Aldo Bonaventura, Davide Santagata, Alessandra Vecchié, Antonio Abbate
Drugs. 2025-05-01
1 citations
Effects of anti-inflammatory therapy in acute heart failure: a systematic review and meta-analysis.
Beth A Davison, Antonio Abbate, Gad Cotter, Domingo Pascual-Figal, Benjamin Van Tassell
Heart Failure Reviews. 2025-05-01
Heart Rate Lowering with Ivabradine and Burden of Symptoms in Patients with Postural Orthostatic Tachycardia Syndrome.
Michele Marchetta, Rocio I Lopez, Austin C Hogwood, Georgia Thomas, Gerardina Abbate
Journal of Cardiovascular Pharmacology. 2025-04-28

Journal Articles

The Present and Future JACC State-of-the-Art Review Stress Cardiomyopathy Diagnosis and Treatment: JACC State-of-the-Art Review
F Gerard Moeller, Antonio Abbate, ScienceDirect

Press Mentions

Ventyx Biosciences Expands SAB with Renowned NLRP3 Experts and Prominent Neurodegenerative and Cardiometabolic Disease SpecialistsApril 1st, 2025
'Pericarditis Does Not Get Enough Attention': UVA Cardiologist Raises Awareness About Rare Heart ConditionDecember 20th, 2024
Condition That Can Feel like a Heart Attack Isn’t Getting ‘Enough Attention’December 8th, 2024
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Grant Support

Modeling of cell-specific LRP1 signaling in acute myocardial infarctionUNIVERSITY OF VIRGINIA2024–2028
Modeling of cell-specific LRP1 signaling in acute myocardial infarctionUNIVERSITY OF VIRGINIA2024–2028
Modeling of cell-specific LRP1 signaling in acute myocardial infarctionUNIVERSITY OF VIRGINIA2024–2028
Prevention of heart failure with IL-1 blockade: a mechanistic studyVIRGINIA COMMONWEALTH UNIVERSITY2022–2027
Unconventional IL-1 Signaling in Heart failureUNIVERSITY OF VIRGINIA2020–2025