AnwaarMohammedSaeedMD

Oncology • Kansas City, KS

Gastrointestinal Cancer

Associate Professor

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Office
Shawnee Mission Parkway
Kansas City, KS 66112
Phone+1 913-588-6029
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Education & Training

University of Kansas School of MedicineFellowship, Hematology and Medical Oncology, 2011 - 2014
University of Missouri-Kansas City School of MedicineResidency, Internal Medicine, 2008 - 2011
Arabian Gulf University College of MedicineClass of 2005

Certifications & Licensure

PA State Medical License 2023 - 2024
KS State Medical License 2016 - 2023
WI State Medical License 2014 - 2017
MO State Medical License 2008 - 2012

Clinical Trials

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair Start of enrollment: 2017 Oct 16
Active, not recruiting
Phase 3
Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer, the COMMIT Study Start of enrollment: 2018 Jan 19
Recruiting
Phase 3
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors Start of enrollment: 2018 Jun 25
Recruiting
Phase 2
Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies Start of enrollment: 2018 Oct 22
Active, not recruiting
Phase 1, Phase 2
A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (mFOLFOX6) in Gastric/Gastroesophageal Junction Cancer Start of enrollment: 2018 Sep 14
Completed
Phase 2
Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE) Start of enrollment: 2019 Feb 06
Active, not recruiting
Phase 2
Rucaparib Plus Ramucirumab With or Without Nivolumab in Advanced Gastric and Esophageal Adenocarcinoma Start of enrollment: 2020 Jan 09
Active, not recruiting
Phase 1, Phase 2
FOLFOXIRI Plus Panitumumab in Metastatic RAS Wild-type, Left-sided Colorectal Cancer Start of enrollment: 2019 Dec 02
Active, not recruiting
Phase 2
Roles: Principal Investigator, Contact
9-ING-41 in Patients With Advanced Cancers Start of enrollment: 2019 Jan 04
Active, not recruiting
Phase 2
Roles: Contact
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Publications & Presentations

PubMed

An initiative to implement a triage and referral system to make exercise and rehabilitation referrals standard of care in oncology.
Kathryn H Schmitz, Andrew Chongaway, Toni Fontana, Kelley Wood, Susan Gibson, Jennifer Trilk, Prajakta Adsul, Stephen Baker, Anwaar Saeed> ;Supportive Care in Cancer. 2024 Apr 2
Differential landscape of immune evasion in oncogenic RAS-driven primary and metastatic colorectal cancers.
Joanne Xiu, Yasmine Baca, Subbaya Subramanian, Timothy K Starr, Elisa Fontana, Ritu Pandey, Matthew Oberley, Andreas Seeber, Emil Lou, Anwaar Saeed, Ajay Prakash, Sepi...> ;Molecular Therapy. Oncology. 2024 Mar 21
Immunotherapy and Radiation Therapy Combinatorial Approaches in Hepatocellular Carcinoma.
Alireza Tojjari, James Yu, Anwaar Saeed> ;Cancers. 2024 Mar 5
Clinical and biomarker results from a phase II trial of combined cabozantinib and durvalumab in patients with chemotherapy-refractory colorectal cancer (CRC): CAMILLA ...
Anwaar Saeed, Robin Park, Harsh Pathak, Ayah Nedal Al-Bzour, Junqiang Dai, Milind Phadnis, Raed Al-Rajabi, Anup Kasi, Joaquina Baranda, Weijing Sun, Stephen Williamson...> ;Nature Communications. 2024 Feb 20
Who Should Receive Immunotherapy for Advanced Gastroesophageal Cancer?
Suhaib Khateeb, Ludimila Cavalcante, Noor Alnairat, Meghana Singh, Ibrahim Halil Sahin, Azhar Saeed, Anwaar Saeed> ;Current Treatment Options in Oncology. 2024 Apr 1
Efficacy and safety of temozolomide-based regimens in advanced pancreatic neuroendocrine tumors: a systematic review and meta-analysis.
Erfan Taherifard, Muhammad Bakhtiar, Mahnoor Mahnoor, Rabeea Ahmed, Ludimila Cavalcante, Janie Zhang, Anwaar Saeed> ;BMC Cancer. 2024 Feb 12
1 citations
Bemarituzumab as first-line treatment for locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma: final analysis of the randomized phase 2 FIG...
Zev A Wainberg, Yoon-Koo Kang, Keun-Wook Lee, Shukui Qin, Kensei Yamaguchi, In-Ho Kim, Anwaar Saeed, Sang Cheul Oh, Jin Li, Haci Mehmet Turk, Alexandra Teixeira, Erika...> ;Gastric Cancer. 2024 May 1
The Efficacy of Immune Checkpoint Inhibitors in Microsatellite Stable Colorectal Cancer: A Systematic Review.
Deniz Can Guven, Gozde Kavgaci, Enes Erul, Masood Pasha Syed, Tara Magge, Anwaar Saeed, Suayib Yalcin, Ibrahim Halil Sahin> ;The Oncologist. 2024 Feb 3
Phase I Study of Elraglusib (9-ING-41), a Glycogen Synthase Kinase-3β Inhibitor, as Monotherapy or Combined with Chemotherapy in Patients with Advanced Malignancies.
Davis, E., Benedito A Carneiro, Ludimila Cavalcante, Devalingam Mahalingam, Anwaar Saeed, Howard Safran, Wen Wee Ma, Andrew L Coveler, Steven Powell, Bruno Bastos, Eli...> ;Clinical Cancer Research. 2024 Feb 1
1 citations
A meta-analysis and real-world cohort study on the sex-related differences in efficacy and safety of immunotherapy for hepatocellular carcinoma.
Lorenz Balcar, Bernhard Scheiner, Claudia Angela Maria Fulgenzi, Antonio D'Alessio, Katharina Pomej, Marta Bofill Roig, Elias Laurin Meyer, Jaekyung Che, Naoshi Nishid...> ;JHEP Reports. 2024 Feb 1
Targeting Angiogenesis Alone and in Combination with Immune Checkpoint Inhibitors in Advanced Gastroesophageal Malignancies.
Tojjari, A., Park, R., Yu, J., Saeed, A.> ;Current Gastroenterology Reports. 2024 Mar 1
Unraveling the puzzle: efficacy of PD-L1 inhibitors in esophageal squamous cell carcinomas with low PD-L1 expression-a comprehensive overview of challenges and limitat...
El Khatib, S., Saeed, A.> ;Translational Cancer Research. 2023 Dec 31
Cancer-Associated Fibroblasts in Gastrointestinal Cancers: Unveiling Their Dynamic Roles in the Tumor Microenvironment.
Noor N Al-Bzour, Ayah N Al-Bzour, Obada E Ababneh, Moayad M Al-Jezawi, Azhar Saeed, Anwaar Saeed> ;International Journal of Molecular Sciences. 2023 Nov 19
4 citations
Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma versus other advanced solid tumours.
Celsa, C., Cabibbo, G., Fulgenzi, C., Scheiner, B., D'Alessio, A., Manfredi, G., Nishida, N., Ang, C., Marron, T., Saeed, A., Wietharn, B., Pinter, M., Cheon, J., Huan...> ;Journal of Hepatology. 2024 Mar 1
2 citations
Baseline neutrophil-lymphocyte ratio and platelet-lymphocyte ratio appear predictive of immune treatment related toxicity in hepatocellular carcinoma.
Dharmapuri, S., Özbek, U., Jethra, H., Jun, T., Marron, T., Saeed, A., Huang, Y., Muzaffar, M., Pinter, M., Balcar, L., Fulgenzi, C., Amara, S., Weinmann, A., Personen...> ;World Journal of Gastrointestinal Oncology. 2023 Nov 15
1 citations
Overcoming Immune Checkpoint Therapy Resistance with SHP2 Inhibition in Cancer and Immune Cells: A Review of the Literature and Novel Combinatorial Approaches.
Alireza Tojjari, Anwaar Saeed, Arezoo Sadeghipour, Razelle Kurzrock, Ludimila Cavalcante> ;Cancers. 2023 Nov 13
1 citations
Efficacy and safety of atezolizumab/bevacizumab in patients with HCC after prior systemic therapy: A global, observational study.
Vincent Joerg, Bernhard Scheiner, Antonio D Alessio, Claudia A M Fulgenzi, Martin Schönlein, Lorenz Kocheise, Ansgar W Lohse, Samuel Huber, Henning Wege, Ahmed Kaseb, ...> ;Hepatology Communications. 2023 Nov 1
SLAM Modification as an Immune-Modulatory Therapeutic Approach in Cancer.
Alireza Tojjari, Francis J Giles, Maysa Vilbert, Anwaar Saeed, Ludimila Cavalcante> ;Cancers. 2023 Sep 29
1 citations
A Meta-Analysis to Assess the Efficacy of HER2-Targeted Treatment Regimens in HER2-Positive Metastatic Colorectal Cancer (mCRC).
Akshit Chitkara, Muhammad Bakhtiar, Ibrahim Halil Sahin, Dennis Hsu, Janie Zhang, Fnu Anamika, Mahnoor Mahnoor, Rabeea Ahmed, Sepideh Gholami, Anwaar Saeed> ;Current Oncology. 2023 Sep 7
Next generation immuno-oncology biomarkers in gastrointestinal cancer: what does the future hold?
Hassan Abushukair, Obada Ababneh, Ayah Al-Bzour, Ibrahim Halil Sahin, Anwaar Saeed> ;Expert Review of Molecular Diagnostics. 2023 Aug 31
2 citations
Anti-Inflammatory and Immune Properties of Polyunsaturated Fatty Acids (PUFAs) and Their Impact on Colorectal Cancer (CRC) Prevention and Treatment.
Alireza Tojjari, Khalil Choucair, Arezoo Sadeghipour, Azhar Saeed, Anwaar Saeed> ;Cancers. 2023 Aug 28
6 citations
A Comprehensive Review on Cancer Vaccines and Vaccine Strategies in Hepatocellular Carcinoma.
Alireza Tojjari, Ahmed Saeed, Ludimila Cavalcante, Ibrahim Halil Sahin, Anwaar Saeed, Meghana Singh> ;Vaccines. 2023 Aug 12
Targeted and Immunotherapy Approaches in HER2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma: A New Era.
Hassan Abushukair, Stijn Hentzen, Ludimila Cavalcante, Anwaar Saeed, Radford, M.> ;Journal of Immunotherapy and Precision Oncology. 2023 Aug 1
Neoadjuvant Immunotherapy for Patients with dMMR/MSI-High Gastrointestinal Cancers: A Changing Paradigm.
Muhammet Ozer, Charan Thej Reddy Vegivinti, Masood Syed, Morgan E Ferrell, Cyndi Gonzalez Gomez, Svea Cheng, Jennifer Holder-Murray, Tullia Bruno, Anwaar Saeed, Ibrahi...> ;Cancers. 2023 Jul 28
2 citations
Efficacy and Safety of Rechallenge with BRAF/MEK Inhibitors in Advanced Melanoma Patients: A Systematic Review and Meta-Analysis.
Jonathan N Priantti, Maysa Vilbert, Thiago Madeira, Francisco Cezar A Moraes, Erica C Koch Hein, Anwaar Saeed, Ludimila Cavalcante> ;Cancers. 2023 Jul 25
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Press Mentions

Cabozantinib plus Durvalumab Shows Efficacy in Subset of Patients with Colorectal CancerJanuary 28th, 2022
Exelixis Announces Detailed Results for Cabozantinib in Combination with Immunotherapies in Patients with Advanced Colorectal Cancer at ASCO GI 2022January 18th, 2022
UW Clinical Trial Holds Hope for Lung Cancer PatientsSeptember 20th, 2016