ArthurEdwardFrankelMD

PubMed

• 90 citations
  First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced...
  Gerald Steven Falchook, Jeffrey R. Infante, Hendrik-Tobias Arkenau, Manish R. Patel, Emma Dean, Erkut Borazanci, Andrew Brenner, Natalie Cook, Juanita Lopez, Shubham P...> ;Eclinicalmedicine. 2021 Mar 30
• 9 citations
  A Phase I/Ib Trial of PD 0332991 (Palbociclib) and T-DM1 in HER2-Positive Advanced Breast Cancer After Trastuzumab and Taxane Therapy.
  Barbara Haley, Kiran Batra, Sunati Sahoo, Thomas W. Froehlich, Dawn Klemow, Nisha Unni, Chul Ahn, Melissa Rodriguez, Melanie Hullings, Arthur E. Frankel> ;Clinical Breast Cancer. 2021 Mar 11
• 32 citations
  Blastic plasmacytoid dendritic cell neoplasms: Results of an international survey on 398 adult patients
  Kamel Laribi, Alix Baugier de Materre, Mohamad Sobh, Lorenzo Cerroni, Caterina Giovanna Valentini, Tomohiro Aoki, Ritsuro Suzuki, Kengo Takeuchi, Arthur E. Frankel, Ca...> ;Blood Advances. 2020 Oct 13
• 7 citations
  Epidermal growth factor receptor-activating mutation(E746_T751>VP) in pancreatic ductal adenocarcinoma responds to erlotinib, followed by epidermal growth factor recep...
  Girijesh Kumar Patel, Josiah B Perry, Osama Abdul-Rahim, Arthur E. Frankel, Daniel Cameron, William R. Taylor, Rodney P. Rocconi, Laith Abushahin, Cindy Nelson, Ajay P...> ;Journal of Cancer Research and Therapeutics. 2020 Jul 1
• 95 citations
  HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma.
  Kevin D. Courtney, Yuanqing Ma, Alberto Diaz de Leon, Alana Christie, Zhiqun Xie, Layton Woolford, Nirmish Singla, Allison Joyce, Haley Hill, Ananth J. Madhuranthakam,...> ;Clinical Cancer Research. 2020 Feb 15
• 11 citations
  The Human Microbiota in Multiple Myeloma and Proteasome Inhibitors
  Omar Alkharabsheh, M. Hasib Sidiqi, Mohammed A. Aljama, Morie A. Gertz, Arthur E. Frankel> ;Acta Haematologica. 2020 Mar 1
• 6 citations
  Autoimmune Bell's Palsy Following Immunotherapy For Metastatic Melanoma: A Report of 2 Cases.
  Daniel Zieman, Arthur E. Frankel> ;Journal of Immunotherapy. 2019 Oct 1
• 12 citations
  The Prevalence of DPYD*9A(c.85T>C) Genotype and the Genotype-Phenotype Correlation in Patients with Gastrointestinal Malignancies Treated With Fluoropyrimidines: Updat...
  Anu Singh Maharjan, Gwendolyn A. McMillin, Girijesh Kumar Patel, Saad Awan, William R. Taylor, Sachin Pai, Arthur E. Frankel, Cindy Nelson, Bin Wang, Peter J. Hosein, ...> ;Clinical Colorectal Cancer. 2019 May 3
• 16 citations
  Exosomal markers (CD63 and CD9) expression and their prognostic significance using immunohistochemistry in patients with pancreatic ductal adenocarcinoma
  Moh’d Khushman, Girijesh Kumar Patel, Javier A. Laurini, Arun Bhardwaj, Kelly Roveda, Robert Donnell, Kelley Sherling, Brittany Case, Arthur E. Frankel, Sachin Pai, Wi...> ;Journal of Gastrointestinal Oncology. 2019 Aug 1
• 41 citations
  Cancer Immune Checkpoint Inhibitor Therapy and the Gut Microbiota.
  Arthur E. Frankel, Sachin Kumar Deshmukh, Amit Reddy, John Lightcap, Maureen Hayes, Steven McClellan, Seema Singh, Brooks D. Rabideau, T. Grant Glover, Bruce L. Robert...> ;Integrative Cancer Therapies. 2019 Apr 23
• 34 citations
  Clinical Activity and Tolerability of SL-401 (Tagraxofusp): Recombinant Diphtheria Toxin and Interleukin-3 in Hematologic Malignancies
  Omar Alkharabsheh, Arthur E. Frankel> ;Biomedicines. 2019 Jan 5
• 51 citations
  Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis
  David E. Gerber, M. Shaalan Beg, Farjana J. Fattah, Arthur E. Frankel, Oluwatomilade Fatunde, Yull Edwin Arriaga, Jonathan E. Dowell, Ajit Kumar Bisen, Richard D. Leff...> ;British Journal of Cancer. 2018 Oct 15
• 16 citations
  Tumor endothelial marker 8 promotes cancer progression and metastasis.
  Anette M. Høye, Sofie D. Tolstrup, Edward R. Horton, Monica Nicolau, Helen Frost, Jung H. Woo, Jeremy P. Mauldin, Arthur E. Frankel, Thomas R. Cox, Janine T. Erler> ;Oncotarget. 2018 Jul 10
• 405 citations
  Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Effi...
  Arthur E. Frankel, Laura A. Coughlin, Jiwoong Kim, Thomas W. Froehlich, Yang Xie, Eugene P. Frenkel, Andrew Y. Koh> ;Neoplasia. 2017 Oct 1
• 975 citations
  Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia
  Eytan M. Stein, Courtney D. DiNardo, Daniel A. Pollyea, Amir T. Fathi, Gail J. Roboz, Jessica K. Altman, Richard Stone, Daniel J. DeAngelo, Ross L. Levine, Ian W. Flin...> ;Blood. 2017 Aug 10
• 473 citations
  A STING-activating nanovaccine for cancer immunotherapy
  Min Luo, Hua Wang, Zhaohui Wang, Haocheng Cai, Zhigang Lu, Yang Li, Mingjian Du, Gang Huang, Chensu Wang, Xiang Chen, Matthew R. Porembka, Jayanthi S. Lea, Arthur E. F...> ;Nature Nanotechnology. 2017 Apr 24
• 33 citations
  Digoxin Plus Trametinib Therapy Achieves Disease Control in BRAF Wild-Type Metastatic Melanoma Patients
  Arthur E. Frankel, Ugur Eskiocak, Jennifer G. Gill, Stacy Yuan, Vijayashree Ramesh, Thomas W. Froehlich, Chul Ahn, Sean J. Morrison> ;Neoplasia. 2017 Apr 1
• 1 citations
  Academic Cancer Center Phase I Program Development
  Arthur E. Frankel, Keith T. Flaherty, George J. Weiner, Robert T. Chen, Nilofer S. Azad, Michael J. Pishvaian, John A. Thompson, Matthew H. Taylor, Daruka Mahadevan, A...> ;The Oncologist. 2017 Apr 1
• 11 citations
  Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells.
  Jacqueline Thorburn, Leah Staskiewicz, Megan L. Goodall, Lina Y. Dimberg, Arthur E. Frankel, Heide L. Ford, Andrew Thorburn> ;Molecular Pharmacology. 2017 Jan 1
• 4 citations
  Blastic plasmacytoid dendritic cell neoplasm with t(11;19)(q23;p13.3);KMT2A(MLL) rearranged: a diagnostic challenge
  Daniel Gehlbach, Prasad Koduru, George B. John, Franklin Fuda, Arthur E. Frankel, Weina Chen> ;British Journal of Haematology. 2017 Jan 1
• 25 citations
  Developing EZH2-Targeted Therapy for Lung Cancer
  Arthur E. Frankel, Xin Liu, John D. Minna> ;Cancer Discovery. 2016 Sep 1
• 33 citations
  Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency
  Lindsay C. Burrage, Qin Sun, Sarah H. Elsea, Ming Ming Jiang, Sandesh C.S. Nagamani, Arthur E. Frankel, Everett Stone, Susan E. Alters, Dale E. Johnson, Scott W. Rowli...> ;Human Molecular Genetics. 2015 Nov 15
• 8 citations
  Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF).
  Amira Bekdash, Manal Darwish, Zahra Timsah, Elias Kassab, Hadi Ghanem, Vicky Najjar, Marwan Ghosn, Selim M. Nasser, Hiba El-Hajj, Ali Bazerbachi, Shihui Liu, Stephen H...> ;Translational Oncology. 2015 Oct 1
• 39 citations
  Resimmune, an anti-CD3ε recombinant immunotoxin, induces durable remissions in patients with cutaneous T-cell lymphoma
  Arthur E. Frankel, Jung H. Woo, Chul Ahn, Francine M. Foss, Madeleine Duvic, Paul H. Neville, David M. Neville> ;Haematologica. 2015 Jun 1
• 49 citations
  Phase I Study of a Bispecific Ligand-Directed Toxin Targeting CD22 and CD19 (DT2219) for Refractory B-cell Malignancies
  Veronika Bachanova, Arthur E. Frankel, Qing Cao, Dixie Lewis, Bartosz Grzywacz, Michael R. Verneris, Celalettin Ustun, Aleksandr Lazaryan, Brian McClune, Erica D. Warl...> ;Clinical Cancer Research. 2015 Mar 15
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