ArunSayramSinghMD

Oncology • Santa Monica, CA

Hematologic Oncology, Sarcoma

Assistant Professor, UCLA School of Medicine

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Office
2020 Santa Monica Boulevard
Suite 580
Santa Monica, CA 90404
Phone+1 310-829-5471

Fax+1 310-829-6192
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Hematology and Medical Oncology, 2008 - 2011
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 2005 - 2008
Rutgers New Jersey Medical SchoolClass of 2005

Certifications & Licensure

CA State Medical License 2008 - 2025

Clinical Trials

Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS) Start of enrollment: 2011 Aug 01
Terminated
Phase 1, Phase 2
Gene and Vaccine Therapy in Treating Patients With Advanced Malignancies Start of enrollment: 2012 Nov 02
Active, not recruiting
Phase 2
A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma Start of enrollment: 2015 Sep 14
Active, not recruiting
Phase 3
Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery Start of enrollment: 2016 Dec 14
Completed
Phase 2
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Publications & Presentations

PubMed

Sarcoma in patients with Lynch syndrome and response to immunotherapy.
Shehata, M., Lofftus, S., Park, J., Singh, A., Federman, N., Eilber, F., Crompton, J., McCaw, T.> ;Journal of Surgical Oncology. 2024 Mar 1
Pilot Study of High-Dose Pemetrexed in Patients with Progressive Chordoma.
Kesari, S., Wagle, N., Carrillo, J., Sharma, A., Nguyen, M., Truong, J., Gill, J., Nersesian, R., Nomura, N., Rahbarlayegh, E., Barkhoudarian, G., Sivakumar, W., Kelly...> ;Clinical Cancer Research. 2024 Jan 17
Primary Cardiac Epithelioid Angiosarcoma with Sustained Remission following Surgical Resection: A Case Report.
May Myint Thanda Kyaw, Eileen Shiuan, Ariannette Yaniz Robledo Gomez, Arun S Singh, Nasser Abdo> ;Case Reports in Oncology. 2023 Sep 12
The Role of Denosumab in the Treatment of Primary Tumors of Bone.
Lauren Elisabeth Wessel, Sophia A Strike, Arun Singh, Nicholas M Bernthal, Edward A Athanasian> ;The Journal of Hand Surgery. 2023 Sep 1
ASO Visual Abstract: Lifelong Imaging Surveillance is Indicated for Patients with Primary Retroperitoneal Liposarcoma.
Mark A Eckardt, Danielle S Graham, Kyle D Klingbeil, Serena Y Lofftus, Tyler R McCaw, Mark J Bailey, Charles J Goldring, Joseph K Kendal, Brian E Kadera, Scott D Nelso...> ;Annals of Surgical Oncology. 2023 May 1
5 citations
Lifelong Imaging Surveillance is Indicated for Patients with Primary Retroperitoneal Liposarcoma.
Mark A Eckardt, Danielle S Graham, Kyle D Klingbeil, Serena Y Lofftus, Tyler R McCaw, Mark J Bailey, Charles J Goldring, Joseph K Kendal, Brian E Kadera, Scott D Nelso...> ;Annals of Surgical Oncology. 2023 May 1
Use of neoadjuvant pexidartinib with limb salvage surgery for diffuse tenosynovial giant cell tumor: A case report.
Erik J Geiger, Andrew R Jensen, Arun S Singh, Scott D Nelson, Nicholas M Bernthal> ;Journal of Orthopaedic Science. 2024 Jan 1
3 citations
Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy.
Zev A Wainberg, Arun S Singh, Gottfried E Konecny, Kelly E McCann, J Randolph Hecht, Jonathan Goldman, Bartosz Chmielowski, Richard S Finn, Neil O'Brien, Erika Von Euw...> ;Clinical Cancer Research. 2023 Jan 4
2 citations
Retrospective analysis of adjuvant treatment for localized, operable uterine leiomyosarcoma.
Jomjit Chantharasamee, Karlton Wong, Pasathorn Potivongsajarn, Amir Qorbani, Neda Motamed, Sandra Brackert, Joshua Cohen, Bartosz Chmielowski, Anusha Kalbasi, Jianyu R...> ;Cancer Medicine. 2022 Aug 1
4 citations
CSF1 receptor inhibition of tenosynovial giant cell tumor using novel disease-specific MRI measures of tumor burden.
Charles Peterfy, Yan Chen, Peter Countryman, Bartosz Chmielowski, Stephen P Anthony, John H Healey, Zev A Wainberg, Allen L Cohn, Geoffrey I Shapiro, Vicki L Keedy, Ar...> ;Future Oncology. 2022 Apr 1
3 citations
Spatial profiling reveals association between WNT pathway activation and T-cell exclusion in acquired resistance of synovial sarcoma to NY-ESO-1 transgenic T-cell ther...
Katie M Campbell, Maneesha Thaker, Egmidio Medina, Anusha Kalbasi, Arun Singh, Antoni Ribas, Theodore Scott Nowicki> ;Journal for Immunotherapy of Cancer. 2022 Mar 1
8 citations
Results from Phase 1 Extension Study Assessing Pexidartinib Treatment in 6 cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT
William D. Tap, Arun S. Singh, Stephen P. Anthony, Mike Sterba, Chao Zhang, John H. Healey, Bartosz Chmielowski, Allen Lee Cohn, Geoffrey I. Shapiro, Vicki L. Keedy, Z...> ;Clinical Cancer Research. 2021 Oct 29
9 citations
Relapse and Treatment Adherence in Patients with Schizophrenia Switching from Paliperidone Palmitate Once-Monthly to Three-Monthly Formulation: A Retrospective Health ...
Gang Li, Alexander Keenan, Mehmet Daskiran, Maju Mathews, Isaac Nuamah, Camille Orman, Kruti Joshi, Arun Singh, A. Godet, Katalin Pungor, Srihari Gopal> ;Patient Preference and Adherence. 2021 Oct 2
4 citations
Aggressive osteoblastoma with a secondary aneurysmal bone cyst treated with denosumab.
Karlton Wong, Jomjit Chantharasamee, Scott D. Nelson, Mark A. Eckardt, Kambiz Motamedi, Francis J. Hornicek, Arun S. Singh> ;Rare Tumors. 2021 Aug 29
17 citations
A Randomized Phase 2 Study Of Nivolumab Monotherapy Or Nivolumab Combined with Ipilimumab In Patients with Advanced Gastrointestinal Stromal Tumors
Arun S. Singh, J. Randolph Hecht, Lee S. Rosen, Zev A. Wainberg, Xiaoyan Wang, Michael Douek, Anahis Hagopian, Rachel Andes, Lauren Sauer, Sandra Brackert, Warren Chow...> ;Clinical Cancer Research. 2021 Aug 18
5 citations
T-LAK cell-originated protein kinase (TOPK): an emerging prognostic biomarker and therapeutic target in osteosarcoma.
Pichaya Thanindratarn, Ran Wei, Dylan C. Dean, Arun S. Singh, Noah Federman, Scott D. Nelson, Francis J. Hornicek, Zhenfeng Duan> ;Molecular Oncology. 2021 Jun 29
1 citations
Kaposi sarcoma in anti-neutrophil cytoplasmic antibody-associated vasculitis: a case-based review
Benedict K. Tiong, Arun S. Singh, G. Peter Sarantopoulos, Tanaz A. Kermani> ;Rheumatology International. 2021 Feb 23
3 citations
Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strategies.
Jomjit Chantharasamee, Jacob J. Adashek, Karlton Wong, Mark A. Eckardt, Bartosz Chmielowski, Sarah M. Dry, Fritz C. Eilber, Arun S. Singh> ;Current Treatment Options in Oncology. 2021 Jan 5
6 citations
Primary Renal Ewing Sarcoma in Children and Young Adults.
Kathryn L. Bradford, Alexander Nobori, Brittany L. Johnson, Wendy Allen-Rhoades, Bindi Naik-Mathuria, Eduard H. Panosyan, Moran Gotesman, Joseph L. Lasky, Jerry Cheng,...> ;Journal of Pediatric Hematology/oncology. 2020 Oct 29
8 citations
Chemotherapy and Survival in Patients with Primary High-Grade Extremity and Trunk Soft Tissue Sarcoma.
Danielle S. Graham, Ritchell van Dams, Nicholas Jackson, Mykola Onyshchenko, Mark A. Eckardt, Benjamin J DiPardo, Scott D. Nelson, Bartosz Chmielowski, Jacob E. Shabas...> ;Cancers. 2020 Aug 24
6 citations
Low Rates of Chemotherapy Use for Primary, High-Grade Soft Tissue Sarcoma: A National Cancer Database Analysis.
Danielle S. Graham, Mykola Onyshchenko, Mark A. Eckardt, Benjamin J DiPardo, Sriram Venigalla, Scott D. Nelson, Bartosz Chmielowski, Arun S. Singh, Jacob E. Shabason, ...> ;Journal of the National Comprehensive Cancer Network. 2020 Aug 1
14 citations
A Phase 1b Dose Escalation Trial of NC-6300 (Nanoparticle Epirubicin) in Patients with Advanced Solid Tumors or Advanced, Metastatic, or Unresectable Soft-tissue Sarcoma.
Sant P. Chawla, Sanjay Goel, Warren Chow, Fadi Braiteh, Arun S. Singh, Juneko E. Grilley Olson, Atsushi Osada, Iulian Bobe, Richard F. Riedel> ;Clinical Cancer Research. 2020 May 7
53 citations
A Phase II Trial of 5-Day Neoadjuvant Radiotherapy for Patients with High-Risk Primary Soft Tissue Sarcoma.
Anusha Kalbasi, Mitchell Kamrava, Fang-I Chu, Donatello Telesca, Ritchell van Dams, Yingli Yang, Dan Ruan, Scott D. Nelson, Sarah M. Dry, J. Hernandez, Bartosz Chmielo...> ;Clinical Cancer Research. 2020 Apr 15
2 citations
Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC-3G3) to patients with advanced soft tissue sarcoma.
Victor M. Villalobos, Gary Mo, Mark Agulnik, Seth M. Pollack, Daniel A. Rushing, Arun S. Singh, Brian A. Van Tine, Rhian McNaughton, Rodney Decker, Wei Zhang, Ashwin S...> ;Cancer Medicine. 2020 Feb 1
23 citations
Use of Denosumab in Children With Osteoclast Bone Dysplasias: Report of Three Cases.
Alexander Upfill-Brown, Susan V. Bukata, Nicholas M. Bernthal, Alan L Felsenfeld, Scott D. Nelson, Arun S. Singh, Katherine Wesseling-Perry, Fritz C. Eilber, Noah Fede...> ;JBMR Plus. 2019 Aug 22
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Journal Articles

Potential of Immunotherapy for Sarcoma
Arun S Singh, Cancer

Lectures

A randomized phase II study of nivolumab monotherapy versus nivolumab combined with ipilimumab in advanced gastrointestinal stromal tumor(GIST).
2019 ASCO Annual Meeting - 6/1/2019

Press Mentions

OncLive® Presents State of the Science Summit™: Treatment of Ovarian CancerMay 21st, 2018
Aura Biosciences Secures $8 Million in Additional Funding and Augments Board of Directors and Clinical Advisory BoardSeptember 29th, 2016