AthenaZuppaMD

Pediatrics • Philadelphia, PA

Pediatric Critical Care Medicine

Associate Professor, Anesthesiology & Critical Care, Perelman School of Medicine

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Office
34th Street & Civic Center Blvd
Suite 9329
Philadelphia, PA 19104
Phone+1 215-590-1858

Fax+1 215-590-4327
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Education & Training

Children's Hospital of PhiladelphiaFellowship, Pediatric Critical Care Medicine, 1999 - 2002
Children's Hospital of PhiladelphiaResidency, Pediatrics, 1996 - 1999
Stony Brook University Health Sciences Center School of MedicineClass of 1996

Certifications & Licensure

PA State Medical License 1997 - 2024
American Board of Pediatrics Pediatric Critical Care Medicine

Clinical Trials

Understanding Dexmedetomidine In Infants Post-Operative From Cardiac Surgery Start of enrollment: 2004 May 01
Completed
Phase 1
Understanding Dexmedetomidine in Neonates After Open Heart Surgery Start of enrollment: 2006 Apr 01
Completed
Phase 1
Pharmacokinetics and Pharmacodynamics of Pentobarbital in Neonates, Infants, and Children Following Open Heart Surgery Start of enrollment: 2006 Apr 01
Terminated
Thyroid Hormones in Critically Ill Children Start of enrollment: 2005 Oct 01
Terminated
Pharmacokinetics and Pharmacdynamics of Sildenafil Start of enrollment: 2008 May 01
Terminated
Pharmacologic Impact on Sedation Assessments Start of enrollment: 2010 Mar 01
Completed
Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients Start of enrollment: 2011 Jul 01
Completed
Phase 3
Hypothermia's Impact on Pharmacology Start of enrollment: 2012 Mar 01
Completed
Medical Cannabis Registry and Pharmacology Start of enrollment: 2018 Jul 15
Completed
GI Medical Cannabis Study on IBD Start of enrollment: 2019 Nov 01
Withdrawn
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products Start of enrollment: 2019 May 15
Terminated
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Publications & Presentations

PubMed

Response to comment on "International consensus recommendations for the use of prolonged-infusion β-lactams endorsed by the American College of Clinical Pharmacy (ACCP...
Hong, L., Downes, K., FakhriRavari, A., Abdul-Mutakabbir, J., Kuti, J., Jorgensen, S., Young, D., Alshaer, M., Bassetti, M., Bonomo, R., Gilchrist, M., Jang, S., Lodis...> ;Pharmacotherapy. 2024 Feb 1
3 citations
Survival With Favorable Neurologic Outcome and Quality of Cardiopulmonary Resuscitation Following In-Hospital Cardiac Arrest in Children With Cardiac Disease Compared ...
Diddle, W. W., Myke Federman, Robert M Sutton, Ron W Reeder, Tageldin Ahmed, Michael J Bell, Robert A Berg, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A C...> ;Pediatric Critical Care Medicine. 2024 Jan 1
Chest compressions for pediatric organized rhythms: A hemodynamic and outcomes analysis.
Diddle, W. W., Zinna, S., Morgan, R., Reeder, R., Ahmed, T., Bell, M., Bishop, R., Bochkoris, M., Burns, C., Carcillo, J., Carpenter, T., Cooper, K., Michael Dean, J.,...> ;Resuscitation. 2024 Jan 1
Bioanalysis of six antibiotics from volumetric microsamples: a new tool for precision dosing in critically ill children.
John Takyi-Williams, Abbie D Leino, Ruiting Li, Kevin J Downes, Athena F Zuppa, Amanda Bwint, Bo Wen, Duxin Sun, Marc H Scheetz, Manjunath P Pai> ;Bioanalysis. 2024 Jan 1
Diuretic Tolerance to Repeated-Dose Furosemide in Infants Born Very Preterm with Bronchopulmonary Dysplasia.
Nicolas A Bamat, Matthew Huber, Justine Shults, Yun Li, Zili Zong, Athena Zuppa, Eric C Eichenwald, Matthew M Laughon, Sara B DeMauro, Kristin J McKenna, Benjamin Lask...> ;The Journal of Pediatrics. 2024 Mar 1
Identification of post-cardiac arrest blood pressure thresholds associated with outcomes in children: an ICU-Resuscitation study.
Diddle, W. W., Monique M Gardner, David A Hehir, Ron W Reeder, Tageldin Ahmed, Michael J Bell, Robert A Berg, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A...> ;Critical Care. 2023 Oct 7
1 citations
Viral Detection by Reverse Transcriptase Polymerase Chain Reaction in Upper Respiratory Tract and Metagenomic RNA Sequencing in Lower Respiratory Tract in Critically I...
Christina M Osborne, Charles Langelier, Jack Kamm, Kayla Williamson, Lilliam Ambroggio, Ron W Reeder, Christopher Locandro, J Kirk Harris, Brandie D Wagner, Aline B Ma...> ;Pediatric Critical Care Medicine. 2024 Jan 1
1 citations
Hyperferritinemic sepsis, macrophage activation syndrome, and mortality in a pediatric research network: a causal inference analysis.
Zhenziang Fan, Kate F Kernan, Yidi Qin, Scott Canna, Robert A Berg, David Wessel, Murray M Pollack, Kathleen Meert, Mark Hall, Christopher Newth, John C Lin, Allan Doc...> ;Critical Care. 2023 Sep 6
1 citations
Association of CPR simulation program characteristics with simulated and actual performance during paediatric in-hospital cardiac arrest.
Katherine Cashen, Robert M Sutton, Ron W Reeder, Tageldin Ahmed, Michael J Bell, Robert A Berg, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A Carcillo, Tod...> ;Resuscitation. 2023 Oct 1
International consensus recommendations for the use of prolonged-infusion beta-lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Socie...
Lisa T Hong, Kevin J Downes, Alireza FakhriRavari, Jacinda C Abdul-Mutakabbir, Joseph L Kuti, Sarah Jorgensen, David C Young, Mohammad H Alshaer, Matteo Bassetti, Robe...> ;Pharmacotherapy. 2023 Aug 1
International consensus recommendations for the use of prolonged-infusion beta-lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Socie...
Lisa T Hong, Kevin J Downes, Alireza FakhriRavari, Jacinda C Abdul-Mutakabbir, Joseph L Kuti, Sarah Jorgensen, David C Young, Mohammad H Alshaer, Matteo Bassetti, Robe...> ;Pharmacotherapy. 2023 Aug 1
1 citations
The Design of Nested Adaptive Clinical Trials of Multiple Organ Dysfunction Syndrome Children in a Single Study.
John M VanBuren, Mark Hall, Athena F Zuppa, Peter M Mourani, Joseph Carcillo, J Michael Dean, Richard Holubkov, Watt, K.> ;Pediatric Critical Care Medicine. 2023 Dec 1
3 citations
Early, Persistent Lymphopenia Is Associated With Prolonged Multiple Organ Failure and Mortality in Septic Children.
Bradley S Podd, Russell K Banks, Ron Reeder, Russell Telford, Richard Holubkov, Joseph Carcillo, Robert A Berg, David Wessel, Murray M Pollack, Kathleen Meert, Mark Ha...> ;Critical Care Medicine. 2023 Dec 1
3 citations
Acute Disorders of Consciousness in Pediatric Severe Sepsis and Organ Failure: Secondary Analysis of the Multicenter Phenotyping Sepsis-Induced Multiple Organ Failure ...
Christina Cheung, Kate F Kernan, Robert A Berg, Athena F Zuppa, Daniel A Notterman, Murray M Pollack, David Wessel, Kathleen L Meert, Mark W Hall, Christopher Newth, J...> ;Pediatric Critical Care Medicine. 2023 Oct 1
1 citations
Optimizing Vancomycin Therapy in Critically Ill Children: A Population Pharmacokinetics Study to Inform Vancomycin Area under the Curve Estimation Using Novel Biomarkers.
Kevin J Downes, Athena F Zuppa, Anna Sharova, Michael N Neely> ;Pharmaceutics. 2023 Apr 25
12 citations
Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study.
Robert A Berg, Ryan W Morgan, Ron W Reeder, Tageldin Ahmed, Michael J Bell, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A Carcillo, Todd C Carpenter, J Mic...> ;Critical Care Medicine. 2023 Jan 1
4 citations
Calcium use during paediatric in-hospital cardiac arrest is associated with worse outcomes.
Katherine Cashen, Robert M Sutton, Ron W Reeder, Tageldin Ahmed, Michael J Bell, Robert A Berg, Candice Burns, Joseph A Carcillo, Todd C Carpenter, J Michael Dean, J W...> ;Resuscitation. 2023 Apr 1
13 citations
Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels.
Christopher M Horvat, Anthony Fabio, Daniel S Nagin, Russell K Banks, Yidi Qin, Hyun-Jung Park, Kate F Kernan, Scott W Canna, Robert A Berg, David Wessel, Murray M Pol...> ;Pediatric Critical Care Medicine. 2022 Dec 1
4 citations
The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes.
Ryan W Morgan, Heather A Wolfe, Ron W Reeder, Jessica S Alvey, Aisha H Frazier, Stuart H Friess, Tensing Maa, Patrick S McQuillen, Kathleen L Meert, Vinay M Nadkarni, ...> ;Pediatric Critical Care Medicine. 2022 Nov 1
9 citations
Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial.
Katherine Cashen, Ron W Reeder, Tageldin Ahmed, Michael J Bell, Robert A Berg, Candice Burns, Joseph A Carcillo, Todd C Carpenter, J Michael Dean, J Wesley Diddle, Myk...> ;Pediatric Critical Care Medicine. 2022 Oct 1
A whole blood microsampling furosemide assay: development, validation and use in a pediatric pharmacokinetic study.
Nicolas A Bamat, Christina Vedar, Megan E Reilly, Ganesh S Moorthy, Athena F Zuppa> ;Bioanalysis. 2022 Aug 1
6 citations
Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome.
Stefanie G Ames, Russell K Banks, Matt S Zinter, Ericka L Fink, Patrick S McQuillen, Mark W Hall, Athena Zuppa, Kathleen L Meert, Peter M Mourani, Joseph A Carcillo, T...> ;Pediatric Critical Care Medicine. 2022 Jul 1
5 citations
Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock.
Ron W Reeder, Russell K Banks, Kathleen L Meert, Robert A Berg, Athena Zuppa, Christopher J Newth, Mark W Hall, Michael Quasney, Anil Sapru, Joseph A Carcillo, Patrick...> ;Pediatric Critical Care Medicine. 2022 Aug 1
A Pharmacokinetic Analysis of Tobramycin in Patients Less than Five Years of Age with Cystic Fibrosis: Assessment of Target Attainment with Extended-Interval Dosing th...
Kevin J Downes, Austyn Grim, Laura Shanley, Ronald C Rubenstein, Athena F Zuppa, Marc R Gastonguay> ;Antimicrobial Agents and Chemotherapy. 2022 May 17
15 citations
Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials.
Yidi Qin, Kate F Kernan, Zhenjiang Fan, Hyun-Jung Park, Soyeon Kim, Scott W Canna, John A Kellum, Robert A Berg, David Wessel, Murray M Pollack, Kathleen Meert, Mark H...> ;Critical Care. 2022 May 7
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Hospital Affiliations

Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania