BarbaraSpitzerMD

PubMed

• High-risk and silent clonal hematopoietic genotypes in patients with nonhematologic cancer.
  Aaron J Stonestrom, Kamal N Menghrajani, Sean M Devlin, Sebastià Franch-Expósito, Ryan N Ptashkin, Swara Y Patel, Barbara Spitzer, Xiaodi Wu, Justin Jee, Pablo Sánchez...> ;Blood Advances. 2024 Feb 27
• Longitudinal clinical data improve survival prediction after hematopoietic cell transplantation using machine learning.
  Yiwang Zhou, Jesse Smith, Dinesh Keerthi, Cai Li, Yilun Sun, Suraj Sarvode Mothi, David C Shyr, Barbara Spitzer, Andrew Harris, Avijit Chatterjee, Subrata Chatterjee, ...> ;Blood Advances. 2024 Feb 13
• 2 citations
  Immune profiling after allogeneic hematopoietic cell transplantation in pediatric acute myeloid leukemia.
  Sanam Shahid, Nicholas Ceglia, Jean-Benoît Le Luduec, Andrew McPherson, Barbara Spitzer, Theodota Kontopoulos, Viktoria Bojilova, M Kazim Panjwani, Mikhail Roshal, Soh...> ;Blood Advances. 2023 Sep 12
• 3 citations
  Durable Engraftment and Excellent Overall Survival After CD34-Selected Peripheral Blood Stem Cell Boost in Pediatric Patients With Poor Graft Function Following Alloge...
  Ellen Fraint, Sana Farooki, Elizabeth Klein, Audrey Mauguen, Susan E Prockop, Andromachi Scaradavou, Kevin Curran, Maria Cancio, Barbara Spitzer, Jaap Jan Boelens, Jos...> ;Transplantation and Cellular Therapy. 2023 Jan 1
• Lack of complete response pretransplant is not associated with inferior overall survival for stage 4a metastatic retinoblastoma.
  Sameer Farouk Sait, Mauricio Rendon Bernot, Elizabeth Klein, David H Abramson, Jasmine H Francis, Stephen Gilheeney, Matthias A Karajannis, Barbara Spitzer, Suzanne Wo...> ;Pediatric Blood & Cancer. 2023 Jan 1
• 4 citations
  De Novo myelodysplastic syndromes in patients 20-50 years old are enriched for adverse risk features.
  Zachary D Epstein-Peterson, Barbara Spitzer, Andriy Derkach, Juan E Arango, Joseph G W McCarter, Juan S Medina-Martínez, Erin McGovern, Noushin Rahnamay Farnoud, Ross ...> ;Leukemia Research. 2022 Jun 1
• 3 citations
  Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia.
  Barbara Spitzer, Kayleigh D Rutherford, Gunes Gundem, Erin M McGovern, Nathan E Millard, Juan E Arango Ossa, Irene Y Cheung, Teng Gao, Max F Levine, Yanming Zhang, Jua...> ;Clinical Cancer Research. 2022 Apr 14
• 11 citations
  Antithymocyte globulin exposure in CD34+ T-cell depleted allogeneic hematopoietic cell transplantation.
  Madhavi Lakkaraja, Michael Scordo, Audrey Mauguen, Christina Cho, Sean M. Devlin, Josel D. Ruiz, Elizabeth Klein, Scott Avecilla, Farid Boulad, Maria Cancio, Kevin J. ...> ;Blood Advances. 2021 Nov 17
• Toward More Complete Prognostication for Patients with Clonal Hematopoiesis.
  Barbara Spitzer, Ross L Levine> ;Blood Cancer Discovery. 2021 May 1
• 7 citations
  ETV6-FLT3-positive myeloid/lymphoid neoplasm with eosinophilia presenting in an infant: an entity distinct from JMML.
  Barbara Spitzer, Filemon S. Dela Cruz, Glorymar D. Ibanez Sanchez, Yanming Zhang, Wenbin Xiao, Ryma Benayed, Alina Markova, M. Irene Rodriguez-Sanchez, Nancy Bouvier, ...> ;Blood Advances. 2021 Apr 13
• 7 citations
  Therapeutic Efficacy of Combined JAK1/2, Pan-PIM, and CDK4/6 Inhibition in Myeloproliferative Neoplasms.
  Raajit K. Rampal, Maria Pinzon-Ortiz, Amritha Varshini Hanasoge Somasundara, Benjamin H. Durham, Richard Koche, Barbara Spitzer, Shoron Mowla, Aishwarya Krishnan, Bing...> ;Clinical Cancer Research. 2021 Jun 15
• 53 citations
  Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis
  Teng Gao, Ryan Ptashkin, Kelly L. Bolton, Maria Sirenko, Christopher J. Fong, Barbara Spitzer, Kamal Menghrajani, Juan E. Arango Ossa, Yangyu Zhou, Elsa Bernard, Max L...> ;Nature Communications. 2021 Jan 12
• 23 citations
  CD4+ T-cell reconstitution predicts Survival Outcomes after acute Graft-versus-Host-Disease; a dual center validation.
  Coco de Koning, Susan E. Prockop, Ichelle van Roessel, Nancy A. Kernan, Elizabeth Klein, Jurgen Langenhorst, Celina L. Szanto, Mirjam E. Belderbos, Marc Bierings, Fari...> ;Blood. 2021 Feb 11
• 281 citations
  Cancer therapy shapes the fitness landscape of clonal hematopoiesis
  Kelly L. Bolton, Ryan Ptashkin, Teng Gao, Lior Z. Braunstein, Sean M. Devlin, Daniel Kelly, Minal Patel, Antonin Berthon, Aijazuddin Syed, Mariko Yabe, Catherine C. Co...> ;Nature Genetics. 2020 Oct 26
• 22 citations
  Early CD4+ T cell reconstitution as predictor of outcomes after allogeneic hematopoietic cell transplantation
  Ichelle van Roessel, Susan E. Prockop, Elizabeth Klein, Farid Boulad, Andromachi Scaradavou, Barbara Spitzer, Andrew L. Kung, Kevin J. Curran, Richard J. O'Reilly, Nan...> ;Cytotherapy. 2020 Sep 1
• 11 citations
  Low toxicity and favorable overall survival in relapsed/refractory B-ALL following CAR T cells and CD34-selected T-cell depleted allogeneic hematopoietic cell transplant.
  Vanessa A Fabrizio, Nancy A. Kernan, Farid Boulad, Maria Cancio, Jennifer Allen, Meghan A. Higman, Steven P. Margossian, Audrey Mauguen, Susan E. Prockop, Andromachi S...> ;Bone Marrow Transplantation. 2020 May 10
• 130 citations
  Off-the-shelf EBV-specific T cell immunotherapy for rituximab-refractory EBV-associated lymphoma following transplantation
  Susan E. Prockop, Ekaterina Doubrovina, Stephanie Suser, Glenn Heller, Juliet N. Barker, Parastoo B. Dahi, Miguel Perales, Esperanza B. Papadopoulos, Craig S. Sauter, ...> ;The Journal of Clinical Investigation. 2020 Feb 3
• 146 citations
  Toxicity and response after CD19-specific CAR T-cell therapy in pediatric/young adult relapsed/refractory B-ALL
  , , , , , , , , , , , , , , , , , , , , , , , , > ;Blood. 2019 Dec 26
• 48 citations
  MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia
  Fiona C. Brown, Eric Still, Richard Koche, Christina Y. Yim, Sumiko Takao, Paolo Cifani, Casie Reed, Shehana Gunasekera, Scott B. Ficarro, Peter Romanienko, Willie Mar...> ;Cancer Discovery. 2018 Apr 1
• 14 citations
  JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
  McKenney, A., Lau, A., Somasundara, A., Spitzer, B., Intlekofer, A., Ahn, J., Shank, K., Rapaport, F., Patel, M., Papalexi, E., Shih, A., Chiu, A., Freinkman, E., Akba...> ;The Journal of Clinical Investigation. 2018 Feb 1
• 6 citations
  Corrigendum: JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition(J Clin Invest. (2018) 128:2 (789–804) DOI: 10.1172/JCI94516)
  Anna Sophia McKenney, Allison N. Lau, Amritha Varshini Hanasoge Somasundara, Barbara Spitzer, Andrew M. Intlekofer, Jihae Ahn, Kaitlyn Shank, Franck Rapaport, Minal Pa...> ;The Journal of Clinical Investigation. 2018 Feb 1
• 7 citations
  A Chemotherapy-Only Regimen of Busulfan, Melphalan, and Fludarabine, and Rabbit Antithymocyte Globulin Followed by Allogeneic T-Cell Depleted Hematopoietic Stem Cell T...
  Barbara Spitzer, Ann A. Jakubowski, Esperanza B. Papadopoulos, Kirsten Fuller, Patrick Hilden, James W. Young, Juliet N. Barker, Guenther Koehne, Miguel-Angel Perales,...> ;Biology of Blood and Marrow Transplantation. 2017 Dec 1
• 169 citations
  DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling
  Olga A. Guryanova, Kaitlyn Shank, Barbara Spitzer, Luisa Luciani, Richard Koche, Francine E. Garrett-Bakelman, Chezi Ganzel, Benjamin H. Durham, Abhinita Mohanty, Greg...> ;Nature Medicine. 2016 Dec 1
• 66 citations
  Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
  Su Fern Tan, Xin Liu, Todd E. Fox, Brian M. Barth, Arati Sharma, Stephen D. Turner, Andy Awwad, Alden Dewey, Kenichiro Doi, Barbara Spitzer, Mithun Vinod Shah, Samy A....> ;Oncotarget. 2016 Nov 4
• 7 citations
  Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status".
  Lindsay M. LaFave, Wendy Béguelin, Richard Koche, Matt Teater, Barbara Spitzer, Alan Chramiec, Efthymia Papalexi, Matthew D. Keller, Todd Hricik, Katerina Konstantinof...> ;Nature Medicine. 2016 Jun 7
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Abstracts/Posters

• Allogeneic CD34-Selected HSCT Following CAR T-Cells Is Associated with Low TRM and Favorable OS in Pediatric/Young Adult Patients with Relapsed/Refractory B-ALL
  Barbara Spitzer, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• De Novo Myelodysplastic Syndromes in Patients 20-50 Years Old Characterized By Frequent Mutations in TP53 and Transcription-Related Genes
  Barbara Spitzer, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019