BarryIEisensteinMD

Infectious Disease • Lexington, MA

Clinical Professor, Medicine, Beth Israel Deaconess Medical Center

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Office
65 Hayden Ave
Lexington, MA 02421
Phone+1 781-860-8310
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Education & Training

University of North Carolina HospitalsFellowship, Infectious Disease, 1975 - 1977
University of North Carolina HospitalsResidency, Internal Medicine, 1972 - 1975
Columbia University Vagelos College of Physicians and SurgeonsClass of 1972

Certifications & Licensure

DC State Medical License 2010 - 2024
MA State Medical License 1997 - 2018
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Infectious Disease

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Publications & Presentations

PubMed

30 citations
Towards a global definition of responsible antibiotic use: results of an international multidisciplinary consensus procedure
Annelie A Monnier, Barry I. Eisenstein, Marlies E J L Hulscher, Inge C. Gyssens> ;The Journal of Antimicrobial Chemotherapy. 2018 Jun 1
46 citations
Progress in the Fight Against Multidrug-Resistant Bacteria 2005-2016: Modern Noninferiority Trial Designs Enable Antibiotic Development in Advance of Epidemic Bacteria...
John H. Rex, George H. Talbot, Mark Goldberger, Barry I. Eisenstein, Roger Echols, John F. Tomayko, Michael N. Dudley, Aaron Dane> ;Clinical Infectious Diseases. 2017 Jul 1
23 citations
The evolution of the regulatory framework for antibacterial agents.
John H. Rex, Mark Goldberger, Barry I. Eisenstein, Carrie Harney> ;Annals of the New York Academy of Sciences. 2014 Sep 1
13 citations
The Challenge of Antimicrobial Resistance: New Regulatory Tools to Support Product Development
John F. Tomayko, John H. Rex, David Tenero, Mark Goldberger, Barry I. Eisenstein> ;Clinical Pharmacology and Therapeutics. 2014 Aug 1
Addressing the need for new antibacterials – Authors' reply
John H. Rex, Barry I. Eisenstein, Jeff Alder, Mark Goldberger, Robert J. Meyer, Aaron Dane, Ian Friedland, Charles Knirsch, Wendy R Sanhai, John F. Tomayko, Cindy Lanc...> ;The Lancet. Infectious Diseases. 2013 Oct 1
95 citations
A comprehensive regulatory framework to address the unmet need for new antibacterial treatments
John H. Rex, Barry I. Eisenstein, Jeff Alder, Mark Goldberger, Robert F. Meyer, Aaron Dane, Ian Friedland, Charles Knirsch, Wendy R Sanhai, John F. Tomayko, Cindy Lanc...> ;The Lancet. Infectious Diseases. 2013 Mar 1
469 citations
Combating antimicrobial resistance: policy recommendations to save lives.
Brad Spellberg, Martin J. Blaser, Robert Guidos, Helen W. Boucher, John S. Bradley, Barry I. Eisenstein, Dale N. Gerding, Ruth Lynfield, L B Reller, John H. Rex, Schwa...> ;Clinical Infectious Diseases. 2011 May 1
5 citations
Decreasing the Probability of Creatine Phosphokinase Elevations: Clinical Considerations for Daptomycin Dosing in Obese Patients
Brian J. Donovan, John F. Mohr, Andrew G Knapp, Barry I. Eisenstein> ;Clinical Infectious Diseases. 2010 Oct 15
98 citations
Daptomycin: From the Mountain to the Clinic, with Essential Help from Francis Tally, MD
Barry I. Eisenstein, Frederick B. Oleson, Richard H. Baltz> ;Clinical Infectious Diseases. 2010 Feb 1
89 citations
Daptomycin versus vancomycin plus gentamicin for treatment of bacteraemia and endocarditis due to Staphylococcus aureus: subset analysis of patients infected with meth...
Susan J. Rehm, Helen W. Boucher, Donald P. Levine, Marilyn Campion, Barry I. Eisenstein, Gloria Vigliani, G. Ralph Corey, Elias Abrutyn> ;The Journal of Antimicrobial Chemotherapy. 2008 Dec 1
23 citations
Treatment challenges in the management of complicated skin and soft-tissue infections.
B.I. Eisenstein> ;Clinical Microbiology and Infection. 2008 Mar 1
4 citations
Treatment of staphylococcal infections with cyclic lipopeptides
B.I. Eisenstein> ;Clinical Microbiology and Infection. 2008 Mar 1
1 citations
Use of daptomycin for treatment of Staphylococcus aureus infections.
Barry I. Eisenstein> ;Expert Opinion on Drug Discovery. 2007 Oct 30
The clinical relevance and correct designation of isolates nonsusceptible to daptomycin.
Jeff Alder, Barry I. Eisenstein> ;Clinical Infectious Diseases. 2005 Aug 1
49 citations
Rifalazil treats and prevents relapse of clostridium difficile-associated diarrhea in hamsters.
Pauline M. Anton, Michael J. O'Brien, Efi Kokkotou, Barry Eisenstein, Arthur F. Michaelis, David M. Rothstein, Sophia Paraschos, Ciaran P. Kelly, Charalabos Pothoulakis> ;Antimicrobial Agents and Chemotherapy. 2004 Oct 1
61 citations
Lipopeptides, focusing on daptomycin, for the treatment of Gram-positive infections.
Barry I. Eisenstein> ;Expert Opinion on Investigational Drugs. 2004 Sep 1
527 citations
The Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-Structure Infections
Robert D. Arbeit, Dennis G. Maki, Francis P. Tally, Edward Campanaro, Barry I. Eisenstein, Investigators> ;Clinical Infectious Diseases. 2004 Jun 15
37 citations
Development potential of rifalazil
David M. Rothstein, Arthur D Hartman, Michael H. Cynamon, Barry Eisenstein> ;Expert Opinion on Investigational Drugs. 2003 Feb 1
38 citations
Human tissue research in the genomic era of medicine: balancing individual and societal interests.
Ted T. Ashburn, Sharon K. Wilson, Barry I. Eisenstein> ;Archives of Internal Medicine. 2000 Dec 11
20 citations
Shuttle mutagenesis of Legionella pneumophila: identification of a gene associated with host cell cytopathicity.
Juan Arroyo, Mary C. Hurley, M Wolf, Mark S. McClain, Barry I. Eisenstein, N C Engleberg> ;Infection and Immunity. 1994 Sep 1
62 citations
Inversion-independent phase variation of type 1 fimbriae in Escherichia coli.
Mark S. McClain, I C Blomfield, K J Eberhardt, Barry I. Eisenstein> ;Journal of Bacteriology. 1993 Jul 1
138 citations
Phenotypic modulation by Legionella pneumophila upon infection of macrophages.
Y abu Kwaik, Barry I. Eisenstein, N C Engleberg> ;Infection and Immunity. 1993 Apr 1
116 citations
Lrp stimulates phase variation of type 1 fimbriation in Escherichia coli K-12.
I C Blomfield, P J Calie, K J Eberhardt, Mark S. McClain, Barry I. Eisenstein> ;Journal of Bacteriology. 1993 Jan 1
18 citations
PhoA gene fusions in Legionella pneumophila generated in vivo using a new transposon, MudphoA
Mark Albano, Juan Arroyo, Barry I. Eisenstein, N. Cary Engleberg> ;Molecular Microbiology. 1992 Jul 1
25 citations
Characterization of a Legionella pneumophila gene encoding a lipoprotein antigen.
N C Engleberg, D. C. Howe, James E. Rogers, Juan Arroyo, Barry I. Eisenstein> ;Molecular Microbiology. 1991 Aug 1
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Journal Articles

Progress in the Fight Against Multidrug-Resistant Bacteria 2005–2016: Modern Noninferiority Trial Designs Enable Antibiotic Development in Advance of Epidemic Bacteria...
Barry I Eisenstein, Roger M Echols, Clinical Infectious Diseases

Lectures