BarryLGauseMD

Oncology • Frederick, MD

Hematologic Oncology, Melanoma

CMO SAIC-F

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Office
5705 Industry Lane
Suite J
Frederick, MD 21701
Phone+1 301-846-6009

Fax+1 301-402-0172
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Education & Training

National Institutes of Health Clinical CenterFellowship, Hematology and Medical Oncology, 1981 - 1984
Emory University School of MedicineResidency, Internal Medicine, 1977 - 1979
Emory University School of MedicineInternship, Transitional Year, 1976 - 1977
Michigan State University College of Human MedicineClass of 1976

Certifications & Licensure

MD State Medical License 1991 - 2024
GA State Medical License 1979 - 1999

Clinical Trials

Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer Start of enrollment: 1995 Nov 01
Completed
Phase 1
Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors Start of enrollment: 1997 Oct 01
Completed
Phase 2

Publications & Presentations

PubMed

Synchronous indolent primary gastrointestinal lymphomas managed successfully with conservative measures.
Andrew S. Brohl, Joo Y. Song, Ron Lieberman, Barry L. Gause> ;American Journal of Therapeutics. 2013 Sep 1
90 citations
MicroRNA profiling of follicular lymphoma identifies microRNAs related to cell proliferation and tumor response.
Weixin Wang, Meghan Corrigan-Cummins, Justin Hudson, Irina Maric, Olga Simakova, Sattva S. Neelapu, Larry W. Kwak, John E. Janik, Barry L. Gause, Elaine S. Jaffe, Kath...> ;Haematologica. 2012 Apr 1
182 citations
Vaccination With Patient-Specific Tumor-Derived Antigen in First Remission Improves Disease-Free Survival in Follicular Lymphoma
Stephen J. Schuster, Sattva S. Neelapu, Barry L. Gause, John E. Janik, Franco M. Muggia, Jon P. Gockerman, Jane N. Winter, Christopher R. Flowers, Daniel A. Nikcevich,...> ;Journal of Clinical Oncology. 2011 Jul 10
Idiotype vaccine therapy (BiovaxID) in follicular lymphoma in first complete remission: Phase III clinical trial results.
Schuster SJ, Neelapu SS, Gause BL, Muggia FM, Gockerman JP, Sotomayor EM, Winter JN, Flowers CR, Stergiou AM, Kwak LW> ;J. Clin. Oncol.. 2009-06-20
Idiotype vaccine therapy (BiovaxID) in follicular lymphoma in first complete remission: Phase III clinical trial results.
Schuster SJ, Neelapu SS, Gause BL, Muggia FM, Gockerman JP, Sotomayor EM, Winter JN, Flowers CR, Stergiou AM, Kwak LW> ;J. Clin. Oncol.. 2009-05-20
25 citations
A novel proteoliposomal vaccine induces antitumor immunity against follicular lymphoma.
Sattva S. Neelapu, Barry L. Gause, Linda K. Harvey, Seung Tae Lee, Andrea Robin Frye, Jessie Horton, Richard J. Robb, Mircea C. Popescu, Larry W. Kwak> ;Blood. 2007 Jun 15
126 citations
A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy
Deirdre O'Mahony, John C. Morris, Cate Quinn, Wendy Gao, Wyndham H. Wilson, Barry L. Gause, Stefania Pittaluga, Sattva S. Neelapu, Margaret R. Brown, Thomas A. Fleishe...> ;Clinical Cancer Research. 2007 Feb 1
Idiotype vaccine therapy of follicular lymphoma in first remission: Association of t(14;18) and disease free survival in a phase II cohort.
Gause BL, Neelapu SS, Cohen CM, Katz LM, Watson T, Stergiou AM, Kwak LW> ;J. Clin. Oncol.. 2006-06-20
Autologous PBMCs pulsed with HPV16 E6 as an immunotherapeutic agent for patients with advanced cervical cancer.
Ibrahim RA, Achtar MS, Herrin VE, Gause B, Bernstein S, Grollman F, Contoise D, Steinberg S, Berzofsky JA, Khleif SN> ;J. Clin. Oncol.. 2005-06-01
Pre-immature dendritic cells pulsed with human papillomavirus 16 E7 peptide vaccine in advanced cervical cancer.
Achtar MS, Ibrahim R, Herrin VE, Gause B, Steinberg S, Grollman F, Rahma O, Bernstein S, Maruffi C, Berzofsky J, Khleif SN> ;J. Clin. Oncol.. 2005-06-01
24 citations
Phase III randomized trial of patient-specific vaccination for previously untreated patients with follicular lymphoma in first complete remission: protocol summary and...
Sattva S. Neelapu, Barry L. Gause, Daniel A. Nikcevich, Stephen J. Schuster, Jane N. Winter, Jon P. Gockerman, Thomas P. Loughran, Ken Takeshita, Giorgio Inghirami, De...> ;Clinical Lymphoma. 2005 Jun 1
61 citations
Human Autologous Tumor-Specific T-Cell Responses Induced by Liposomal Delivery of a Lymphoma Antigen
Sattva S. Neelapu, Sivasubramanian Baskar, Barry L. Gause, Carol B. Kobrin, Thelma M. Watson, Andrea Robin Frye, Robin Pennington, Linda K. Harvey, Elaine S. Jaffe, Ri...> ;Clinical Cancer Research. 2004 Dec 15
Vaccine therapy with tumor specific mutated VHL peptides in adult cancer patients with renal cell carcinoma.
Achtar MS, Ibrahim RA, Herrin VE, Gause B, Bernstein SA, Brent-Steel TB, Maruffi CM, Berzofsky JA, Khleif SN> ;J. Clin. Oncol.. 2004-07-15
Mutant P53 vaccination of patients with advanced cancers generates specific immunological responses.
Ibrahim RA, Achtar MS, Herrin VE, Gause B, Bernstein SA, Brent-Steel TB, Maruffi CM, Berzofsky JA, Khleif SN> ;J. Clin. Oncol.. 2004-07-15
6 citations
Interactions between genetic and reproductive factors in breast cancer risk in a population-based sample of African-American families.
Valérie Chaudru, A. E. Laing, Georgia M. Dunston, Lucile L. Adams-Campbell, R. Williams, John J. Lynch, LaSalle D. Leffall, Robert L. DeWitty, Barry L. Gause, George E...> ;Genetic Epidemiology. 2002 Apr 1
15 citations
A prospective randomized phase II trial of GM-CSF priming to prevent topotecan-induced neutropenia in chemotherapy-naive patients with malignant melanoma or renal cell...
John E. Janik, Langdon L. Miller, Edward L. Korn, Diane Stevens, Brendan D. Curti, M Sznol, Kevin C. Conlon, William H. Sharfman, W J Urba, Barry L. Gause, Dan L. Longo> ;Blood. 2001 Apr 1
22 citations
Combination chemotherapy followed by an immunotoxin (anti-B4-blocked ricin) in patients with indolent lymphoma: results of a phase II study.
Dan L. Longo, P L Duffey, John G. Gribben, Elaine S. Jaffe, Brendan D. Curti, Barry L. Gause, John E. Janik, Virginia M. Braman, Dixie Lee Esseltine, Wyndham H. Wilson...> ;Cancer Journal. 2000 May 1
9 citations
Elevations in serum soluble interleukin-2 receptor levels predict relapse in patients with hairy cell leukemia.
Banu Arun, Brendan D. Curti, Dan L. Longo, Diane Stevens, W. Gregory Alvord, Barry L. Gause, Thelma Watson, William Kopp, John E. Janik> ;The Cancer Journal from Scientific American. 2000 Jan 1
17 citations
Treatment with tumor necrosis factor-α and granulocyte-macrophage colony-stimulating factor increases epidermal Langerhans' cell numbers in cancer patients
John E. Janik, Langdon L. Miller, William C. Kopp, Dennis D. Taub, Harry D. Dawson, Diane Stevens, Paige Kostboth, Brendan D. Curti, Kevin C. Conlon, Barbara K. Dunn, ...> ;Clinical Immunology. 1999 Dec 1
470 citations
Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma.
Maurizio Bendandi, Christopher D. Gocke, Carol B. Kobrin, Floyd A. Benko, Lars Sternas, Robin Pennington, Thelma M. Watson, Craig W. Reynolds, Barry L. Gause, P L Duff...> ;Nature Medicine. 1999 Oct 1
17 citations
Abrogation of the Hematological and Biological Activities of the Interleukin-3/Granulocyte-Macrophage Colony-Stimulating Factor Fusion Protein PIXY321 by Neutralizing ...
Langdon L. Miller, Edward L. Korn, Diane Stevens, John E. Janik, Barry L. Gause, William C. Kopp, Jon Holmlund, Brendan D. Curti, Mario Sznol, Walter J. Urba, Sarah E....> ;Blood. 1999 May 15
42 citations
Phase I trial of anti-CD3-stimulated CD4+ T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer
Brendan D. Curti, Augusto C. Ochoa, G C Powers, William C. Kopp, W G Alvord, John E. Janik, Barry L. Gause, B Dunn, M S Kopreski, Robert G. Fenton, Arnold H. Zea, C Da...> ;Journal of Clinical Oncology. 1998 Aug 1
8 citations
Development of rheumatoid arthritis after treatment of large granular lymphocyte leukemia with deoxycoformycin.
Joe Yoe, Barry L. Gause, Brendan D. Curti, Dan L. Longo, Adam Bagg, William Kopp, John E. Janik> ;American Journal of Hematology. 1998 Mar 1
6 citations
A phase II study of carboplatin, cisplatin, interferon-alpha, and tamoxifen for patients with metastatic melanoma.
Barry L. Gause, W. H. Sharfman, John E. Janik, Brendan D. Curti, Ronald G. Steis, Urba Wj, Smith Jw nd, Alvord Wg, Dan L. Longo> ;Cancer Investigation. 1998 Jan 1
175 citations
Interleukin 1α Increases Serum Leptin Concentrations in Humans
John E. Janik, Brendan D. Curti, Robert V. Considine, Helen Rager, Geraldine C. Powers, W. Gregory Alvord, Barry L. Gause, William Kopp> ;The Journal of Clinical Endocrinology and Metabolism. 1997 Sep 1
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