Bassel Fouad El-Rayes MD

PubMed

• XL888 and pembrolizumab modulate the immune landscape of colorectal tumors in a phase Ib/II clinical trial.
  Maggie J Phillips, Olatunji B Alese, Natalie K Horvat, Emily Greene, Olumide B Gbolahan
  Oncoimmunology. 2025-12-01
• BPI25-016: Real-World Outcomes of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: Insights From a Single Center in the Deep South.
  Todd William Mudd, Faris A Abby, Darryl Outlaw, Mehmet Akce, Bassel El-Rayes
  Journal of the National Comprehensive Cancer Network. 2025-03-28
• ADT-1004: a first-in-class, oral pan-RAS inhibitor with robust antitumor activity in preclinical models of pancreatic ductal adenocarcinoma.
  Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, Julienne L Carstens, Jeremy B Foote
  Molecular Cancer. 2025-03-13

Journal Articles

• "Heat Shock Protein 90 (HSP90) Promotes Epithelial to Mesenchymal Transition, Invasion, and Migration in Colorectal Cancer"  
  Nagaraju GP, Long TE, Park W, Landry JC,Taliaferro-Smith L, Farris AB, Diaz R, El-Rayes BF, Mol Carcinog, 1/27/2014
• "Cost Effectiveness Analysis of Pharmacokinetically-Guided 5-Fluorouracil in FOLFOX Chemotherapy for Metastatic Colorectal Cancer"  
  Goldstein DA, Chen Q, Ayer T, Howard DH, Lipscomb J, Harvey RD, El-Rayes BF, Flowers CR, Clin Colorectal Cancer, 1/21/2014
• "HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy"  
  Nagaraju GP, Alese OB, Landry J, Diaz R, El-Rayes BF, Oncotarget, 1/16/2014
• "Hepatoid Adenocarcinoma of the Lung: A Case Report and Review of the Literature"  
  Shaib W, Sharma R, Mosunjac M, Farris AB 3rd, El Rayes B, Journal of Gastrointestinal Cancer, 1/10/2014
• "HER2 in resected gastric cancer: Is there prognostic value?"  
  Fisher SB, Fisher KE, Squires MH 3rd, Patel SH, Kooby DA, El-Rayes BF, Cardona K, Russell MC, Staley CA 3rd, Farris AB 3rd, Maithel SK, J Surg Oncol, 1/1/2014
• "Imaging and curcumin delivery in pancreatic cancer cell lines using PEGylated aplha-Gd2(MoO4)3 mesoporous particles"  
  Seeta Rama Raju G, Pavitra E, Purnachandra Nagaraju G, Ramesh K, El-Rayes BF, Yu JS, Dalton Trans, 1/1/2014
• "Modified response evaluation criteria in solid tumors and European Association for The Study of the Liver criteria using delayed-phase imaging at an early time point ...  
  Camacho JC, Kokabi N, Xing M, Prajapati HJ, El-Rayes B, Kim HS, J Vasc Interv Radiol, 1/1/2014
• "Chromodomain-Helicase-DNA-Binding Protein 7 (CHD7) expression predicts survival outcomes in patients with resected pancreatic cancer"  
  Colbert LE, Petrova AV, Fisher SB, Pantazides BG, Madden MZ, Hardy CW, Warren MD, Pan Y, Nagaraju GP, Liu, EA, Saka B, Hall WA, Shelton JW, Gandhi K, Pauly R, Kowalski..., Am J Clin Oncol, 1/1/2014
• "Clinicopathologic Features and Outcome of Young Adults with Stage IV Colorectal Cancer"  
  Hawk NN, Long T, Imam MH, Mathew BM, Kim S, Chen Z, Goodman M, Sullivan P, Brutcher E, Kauh J, Maithel SK, Adsay VN, Farris AB, El-Rayes BF, Am Journal of Clinical Onc, 1/1/2014
• "Locoregional therapies for metastatic colorectal carcinoma to the liver-An evidence-based review"  
  Xing M, Kooby DA, El-Rayes BF, Kokabi N, Camacho JC, Kim HS, J Surg Oncol, 1/1/2014
• "Value of intraoperative neck margin analysis during whipple for pancreatic adenocarcinoma: a multicenter analysis of 1399 patients"  
  Kooby DA, Lad NL, Squires MH 3rd, Maithel SK, Sarmiento JM, Staley CA, Adsay NV, El-Rayes BF, Weber SM, Winslow ER, Cho CS, Zavala KA, Bentrem DJ, Knab M, Ahmad SA, Ab..., Ann Surg, 1/1/2014
• "Targeted therapies in metastatic esophageal cancer: Advances over the past decade"  
  Mohamed A, El-Rayes B, Khuri, FR, Saba NF, Crit Rev Oncol Hematol, 1/1/2014
• "Phase 1/2 study of KRN330, a fully human anti-A33 monoclonal antibody, plus irinotecan as second-line treatment for patients with metastatic colorectal cancer"  
  Bendell JC, Lenz HJ, Ryan T, El-Rayes BF, Marshall JL, Modiano MR, Hart LL, Kingsley CD, George TJ, Nakashima D, Berlin JD, Invest New Drugs, 1/1/2014
• "Molecular mechanisms underlying the divergent roles of SPARC in human carcinogenesis"  
  Nagaraju GP, Dontula R, El-Rayes BF, Lakka SS, Carcinogenesis, 1/1/2014
• "Pronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic Adenocarcinoma"  
  Colbert LE, Fisher SB, Hardy CW, Hall WA, Saka B, Shelton JW, Petrova AV, Warren MD, Pantazides BG, Gandhi K, Kowalski J, Kooby DA, El-Rayes BF, Staley CA 3rd, Adsay N..., Cancer, 1/29/2013
• "Differential expression and prognostic value of ERCC1 and thymidylate synthase in resected gastric adenocarcinoma"  
  Squires MH 3rd, Fisher SB, Fisher KE, Patel SH, Kooby DA, El-Rayes BF, Staley CA 3rd, Farris AB 3rd, Maithel SK, Cancer, 1/29/2013
• "In Vitro and In Vivo Enhancement of Chemoradiation Using the Oral PARP Inhibitor ABT-888 in Colorectal Cancer Cells"  
  Shelton JW, Waxweiler TV, Landry J, Gao H, Xu Y, Wang L, El-Rayes B, Shu HK, Int J Radiat Oncol Biol Phys, 1/26/2013
• "Low CHD5 Expression Activates the DNA Damage Response and Predicts the Poor Outcome in Patients Undergoing Adjuvant Therapy for Resected Pancreatic Adenocarcinoma"  
  Hall WA, Petrova AV, Colbert LE, Hardy CW, Fisher SB, Saka B, Shelton JW, Warren MD, Pantazides BG, Gandhi K, Kowalski J, Kooby DA, El-Rayes BF, Staley CA, Adsay NV, C..., Oncogene, 1/25/2013
• "Incidence and prognosis of gastroesophageal cancer in rural, urban and metropolitan areas of the United States"  
  Wang Z, Goodman M, Saba N, El-Rayes BF, Cancer, 1/20/2013
• "Carbohydrate antigen 19-9 is a Prognostic and Predictive Biomarker in Patients with Advanced Pancreatic Cancer who Receive Gemcitabine-containing Chemotherapy: A Pool...  
  Bauer TM, El-Rayes BF, Li X, Hammad N, Philip PA, Shields AF, Zalupski MM, Bekaii-Saab T, Cancer, 1/15/2013
• "An analysis of Human Equilibrative Nucleoside Transporter-1, Ribonucleoside Reductase Subunit M1, Ribonucleoside Reductase Subunit M2, and Excision Repair Cross-compl...  
  Fisher SB, Patel SH, Bagci P, Kooby DA, El-Rayes BF, Staley CA 3rd, Adsay NV, Maithel SK, Cancer, 1/15/2013
• "Excision Repair Cross-complementing Gene-1, Ribonucleotide Reductase Subunit M1, Ribonucleotide Reductase Subunit M2, and Human Equilibrative Nucleoside Transporter-1...  
  Fisher SB, Fisher KE, Patel SH, Lim MG, Kooby DA, El-Rayes BF, Staley CA 3rd, Adsay NV, Farris AB 3rd, Maithel SK, Cancer, 1/15/2013
• "Treatment Utilization and Surgical Outcome of Ampullary and Duodenal Adenocarcinoma"  
  Shaib WL, Sharma R, Brutcher E, Kim S, Maithel SK , Chen Z, Kooby DA, Kauh J, Landry J, El-Rayes BF, J Surg Oncol, 1/11/2013
• "Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1aplha and STAT-3"  
  Ganji PN, Park W, Wen J, Mahaseth H, Landry J, Farris AB, Willingham F, Sullivan PS, Proia DA, El-Hariry I, Taliaferro-Smith L, Diaz R, El-Rayes BF, Angiogenesis, 1/10/2013
• "Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer"  
  Nagaraju GP, Zhu S, Wen J, Farris AB, Adsay VN, Diaz R, Snyder JP, Mamoru S, El-Rayes BF, Cancer Letters, 1/7/2013
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Books/Book Chapters

• Gastrointestinal Malignancies: New Innovative Diagnostics and Treatment 
  Cai Q, Xu H, El-Rayes B, Staley CAWorld Science Publishing Co. Pte. Ltd., Singapore2013
• Pancreatic Cancer-Clinical Management 
  Chapter: "Pancreatic Neuroendocrine Tumours: Emerging Management Paradigm" 
  Zafar SF, El-Rayes BEditors: S. Srivastava.2012
• Biliary Tract & Gallbladder Cancer: A Multidisciplinary Approach 
  Chapter: Systemic Therapy for Biliary Cancer. 
  El-Rayes B, Philip PEditors: C.R. Thomas & C. D. Fuller.New York, NY2009
• Pancreatic Cancer 
  Chapter: An Overview of Clinical Trials of Targeted Therapies in Pancreatic Cancer. 
  Page 565 - 575El-Rayes BSpringer, USA2008
• Encyclopaedia of Cancer 
  Chapter: Erlotinib. 
  B.F. El-Rayes, S. Gadgeel, S. Ali, P.A. Philip, F.H. SarkarSpringer, Berlin2008
• Encyclopaedia of Cancer 
  Chapter: Bryostatin-1. 
  B. El-Rayes2008
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Abstracts/Posters

• "Antiangiogenic activity of the HSP90 inhibitor ganetespib in pancreatic cancer models."
  P. N. Ganji, R. Diaz, B. F. El-Rayes, The Federation of American Society for Experimental Biology, 1/1/2013
• "Anti-angiogenic effects of curcumin and its novel analogs EF-31 and UBS-109 in colorectal cancer."
  P. N. Ganji, S. Zhu, J. E. Ko, M. Shoji, B. F. El-Rayes, The Federation of American Society for Experimental Biology, 1/1/2013
• "A comparison of advanced pancreatic cancer patients treated on clinical trials with those from a SEER registry over an 18 year period."
  B.F. El-Rayes, Gastrointestinal Cancers Symposium, 1/1/2008
• "A comparison of advanced pancreatic cancer patients treated on clinical trials with those from a SEER registry over an 18 year period."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2008
• "A phase II study of Bevacizumab, docetaxel, and oxaliplatin in gastric and gastreosophageal junction (GEJ) cancer."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2008
• "A phase II study of Bevacizumab, docetaxel, and oxaliplatin in gastric and gastreosophageal junction (GEJ) cancer."
  B.F. El-Rayes, Gastrointestinal Cancers Symposium, 1/1/2008
• "A phase II study of isoflavone (Novasoy), gemcitabine, and erlotinib in locally advanced (LA) or metastatic pancreatic cancer."
  B.F. El-Rayes, Gastrointestinal Cancers Symposium, 1/1/2008
• "A phase II study of isoflavone (Novasoy), gemcitabine, and erlotinib in locally advanced (LA) or metastatic pancreatic cancer."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2008
• "Activity and safety of carboplatin and paclitaxel followed by capecitabine and radiation as adjuvant therapy for gastric cancer (GC)."
  B.F. El-Rayes, Gastrointestinal Cancers Symposium, 1/1/2008
• "Activity of safety of carboplatin and paclitaxel followed by capecitabine and radiation as adjuvant therapy for gastric cancer (GC)."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2007
• "A does attenuated schedule of irinotecan and capecitabine in combination with celecoxib in advanced colorectal cancer."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2006
• "A does attenuated schedule of irinotecan and capecitabine in combination with celecoxib in advanced colorectal cancer."
  B.F. El-Rayes, Gastrointestinal Cancers Symposium, 1/1/2006
• "A retrospective review of anal squamous cell carcinoma in HIV positive and HIV negative patients."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2006
• "The role of venography in the evaluation of malfunctioning central venous access ports (CVAPs)."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2006
• "A Phase II Trial of Celecoxib, Irinotecan, and Capecitabine in Metastatic Colorectal Cancer."
  B.F. El-Rayes, Gastrointestinal Cancers Symposium, 1/1/2005
• "A Phase II Trial of Celecoxib, Irinotecan, and Capecitabine in Metastatic Colorectal Cancer."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2005
• "A Phase II Trial of carboplatin, gemcitabine and capecitabine in patients with carcinoma of unknown primary site (CUP)."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2005
• "CA 19-9 as a predictor of response and survival in patients with pancreatic cancer treated with gemcitabine and cisplatin based chemotherapy."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2005
• "Phase II study of capecitabine, irinotecan, and celecoxib in advanced colorectal cancer."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2004
• "A Phase II study of Gemcitabine by fixed-dose rate infusion, cisplatin and celecoxib in metastatic pancreatic cancer."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2004
• "Targeting the Epidermal Growth Factor Receptor (EGFR) and Cyclooxygenase-2 (COX-2) pathways in Pancreatic Cancer."
  B.F. El-Rayes, GI Oncology Symposium, 1/1/2004
• "Phase I Study of flavopiridol and docetaxel."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2003
• "Protein Kinase C (PKC): A Target for Therapy in Pancreatic Cancer."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2003
• "Phase I Study of the Protein Kinase C Modulator Bryostatain 1, and Gemcitabine."
  B.F. El-Rayes, Proceedings of ASCO, 1/1/2003
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Lectures

• Hematology/Oncology Grand Rounds, "Pancreatic Cancer: Current Status and Future Directions" 
  University of Cincinnati, Cincinnati, OH - 1/1/2014
• "Optimizing sequencing for colorectal cancer-What is best when?" 
  Sea Island, GA - 1/1/2014
• "A Closer Look at Targeted Therapies in Metastatic Colorectal Cancer" 
  Gaylord Palms Resort, Orlando, FL - 1/1/2013
• Hematology Oncology Grand Rounds: "Pancreatic Cancer Current Status and Future Direction" 
  University of Cincinnati, Cincinnati, OH - 1/1/2013
• "Gastrointestinal Malignancies" 
  Atlanta, GA - 1/1/2013
• "Translational GI Oncology Research at Emory" 
  Atlanta, GA - 1/1/2013
• "Gastrointestinal Cancers: Abstract Presentations and Questions" 
  Atlanta, GA - 1/1/2013
• "India-US Symposium on Translational Research in Oncology" 
  India - 1/1/2012
• "Gemcitabine Based Chemo for Pancreatic Cancer is Standard" 
  Sea Island, GA - 1/1/2012
• "Systemic Treatment of Pancreatic Neuroendocrine Tumor" 
  Sea Island, GA - 1/1/2012
• "Personalized Medicine in Colorectal and Gastric Cancer" 
  Sea Island, GA - 1/1/2012
• "American Society of Clinical Oncology Leadership Skills Seminar" 
  ASCO Headquarters, Alexandria, VA - 1/1/2012
• "Emory Symposium on Image-Guided Cancer Therapies" 
  Atlanta, GA - 1/1/2012
• Session Chair, " NET Management Strategies: What's New & Relevant?" 
  Coronado Island Marriott Hotel, San Diego, CA - 1/1/2012
• "Keynote Speaker, Seventh Annual State of the Art Treatment of GASTROINTESTINAL CANCERS" 
  The Somerset Inn, Troy, MI - 1/1/2012
• "CTO Structure Supporting Winship GI Group" 
  Columbus, OH - 1/1/2012
• Medicine Grand Rounds: "Recent Development in Colorectal Cancer" 
  Emory University School of Medicine, Atlanta, GA - 1/1/2011
• Medical Grand Rounds: "Recent Advances in the Management of Pancreatic Cancer" 
  Roswell Park Cancer Institute, Buffalo, NY - 1/1/2011
• "Preoperative vs. Adjunct Therapy for GI Cancers" 
  Sea Island, GA - 1/1/2011
• "Ganetespib in Rectal Cancer" 
  New York, NY - 1/1/2011
• "The Screening, Prevention & Treatment of Colorectal Cancer" 
  Decatur, GA - 1/1/2011
• GI Grand Rounds: "Pancreatic Cancer" 
  Emory University School of Medicine - 1/1/2011
• Medicine Grand Rounds: "Management of Colorectal Cancer" 
  Emory University School of Medicine - 1/1/2011
• "Colon and Rectal Cancer Updates after ASCO 2011" 
  Konya, Turkey - 1/1/2011
• "IHPBA 2010" 
  Buenos Aires, Argentina - 1/1/2010
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Other

• "Gastrointestinal Malignancies: New Innovative Diagnostics and Treatment, World Science Publishing Co. Pte. Ltd., Singapore" 
  Cai Q, Xu H, El-Rayes B, Kooby D (editors)
  1/1/2013
• Interview: "Breast Cancer in patients with HIV" 
  Bassel F. El-Rayes, MD, HIV Plus
  1/1/2003