BeatrixBartokMD

PubMed

• 3 citations
  Efficacy and Safety of Filgotinib in Patients with High Risk of Poor Prognosis Who Showed Inadequate Response to MTX: A Post Hoc Analysis of the FINCH 1 Study.
  Bernard G Combe, Yoshiya Tanaka, Maya H Buch, Peter Nash, Gerd R Burmester, Alan J Kivitz, Beatrix Bartok, Alena Pechonkina, Katrina Xia, Kahaku Emoto, Shungo Kano, Th...> ;Rheumatology and Therapy. 2023 Feb 1
• Correction: Efficacy and Safety of Filgotinib in Patients with High Risk of Poor Prognosis Who Showed Inadequate Response to MTX: A Post Hoc Analysis of the FINCH 1 St...
  Bernard G Combe, Yoshiya Tanaka, Maya H Buch, Peter Nash, Gerd R Burmester, Alan J Kivitz, Beatrix Bartok, Alena Pechonkina, Katrina Xia, Kahaku Emoto, Shungo Kano, Th...> ;Rheumatology and Therapy. 2023 Feb 1
• 3 citations
  Benefit of Filgotinib, a JAK1 Preferential Inhibitor, in Rheumatoid Arthritis Patients with Previous Rapid Radiographic Progression: Post Hoc Analysis of Two Trials.
  Yoshiya Tanaka, Tatsuya Atsumi, Daniel Aletaha, Beatrix Bartok, Alena Pechonkina, Ling Han, Kahaku Emoto, Shungo Kano, Vijay Rajendran, Tsutomu Takeuchi> ;Rheumatology and Therapy. 2023 Feb 1
• 1 citations
  Integrated safety analysis of filgotinib treatment for rheumatoid arthritis in patients from Japan over a median of 1.5 years.
  Naoki Ishiguro, Yoshiya Tanaka, Tsukasa Matsubara, Tatsuya Atsumi, Koichi Amano, Eiji Sugiyama, Kunihiro Yamaoka, Kevin Winthrop, Alan Kivitz, Gerd R Burmester, Jacque...> ;Modern Rheumatology. 2023 Jan 3
• 1 citations
  Long-term safety and efficacy of filgotinib treatment for rheumatoid arthritis in Japanese patients naïve to MTX treatment (FINCH 3).
  Tatsuya Atsumi, Yoshiya Tanaka, Tsukasa Matsubara, Koichi Amano, Naoki Ishiguro, Eiji Sugiyama, Kunihiro Yamaoka, René Westhovens, Daniel W T Ching, Osvaldo Daniel Mes...> ;Modern Rheumatology. 2023 Jul 4
• 1 citations
  Safety and efficacy of filgotinib for Japanese patients with RA and inadequate response to MTX: FINCH 1 52-week results and FINCH 4 48-week results.
  Yoshiya Tanaka, Tsukasa Matsubara, Tatsuya Atsumi, Koichi Amano, Naoki Ishiguro, Eiji Sugiyama, Kunihiro Yamaoka, Bernard G Combe, Alan J Kivitz, Sang-Cheol Bae, Edwar...> ;Modern Rheumatology. 2023 Jul 4
• 4 citations
  Exposure-response relationships for the efficacy and safety of filgotinib and its metabolite GS-829845 in subjects with rheumatoid arthritis based on phase 2 and phase...
  Amy Meng, Kacey Anderson, Cara Nelson, Liyun Ni, Shu-Min Chuang, Francesco Bellanti, Peter Chang, Craig Comisar, Brian P Kearney, Beatrix Bartok, Anita Mathias> ;British Journal of Clinical Pharmacology. 2022 Jul 1
• 7 citations
  Efficacy and safety of filgotinib in combination with methotrexate in Japanese patients with active rheumatoid arthritis who have an inadequate response to methotrexat...
  Yoshiya Tanaka, Tsukasa Matsubara, Tatsuya Atsumi, Koichi Amano, Naoki Ishiguro, Eiji Sugiyama, Kunihiro Yamaoka, Bernard G Combe, Alan J Kivitz, Sang-Cheol Bae, Edwar...> ;Modern Rheumatology. 2022 Feb 28
• 2 citations
  Efficacy and safety of filgotinib alone and in combination with methotrexate in Japanese patients with active rheumatoid arthritis and limited or no prior exposure to ...
  Tatsuya Atsumi, Yoshiya Tanaka, Tsukasa Matsubara, Koichi Amano, Naoki Ishiguro, Eiji Sugiyama, Kunihiro Yamaoka, René Westhovens, Daniel W T Ching, Osvaldo Daniel Mes...> ;Modern Rheumatology. 2022 Feb 28
• 38 citations
  Integrated safety analysis of filgotinib in patients with moderately to severely active rheumatoid arthritis receiving treatment over a median of 1.6 years.
  Kevin L. Winthrop, Yoshiya Tanaka, Tsutomu Takeuchi, Alan Kivitz, Franziska Matzkies, Mark C. Genovese, Deyuan Jiang, Kun Chen, Beatrix Bartok, Angelika Jahreis, R. Be...> ;Annals of the Rheumatic Diseases. 2021 Nov 5
• 10 citations
  Efficacy and safety of filgotinib in methotrexate-naive patients with rheumatoid arthritis with poor prognostic factors: Post hoc analysis of FINCH 3
  Daniel Aletaha, Rene Westhovens, Cécile Gaujoux-Viala, Giovanni Adami, Alan Matsumoto, Paul Bird, Osvaldo D. Messina, Maya H Buch, Beatrix Bartok, Z. Yin, Ying Guo, Th...> ;RMD Open. 2021 Aug 1
• 102 citations
  Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial.
  Bernard Combe, Alan Kivitz, Yoshiya Tanaka, Désirée van der Heijde, J. Abraham Simon, Herbert S B Baraf, Uma Kumar, Franziska Matzkies, Beatrix Bartok, Lei Ye, Ying Gu...> ;Annals of the Rheumatic Diseases. 2021 Jan 27
• 2 citations
  Efficacy and safety of filgotinib in Japanese patients with refractory rheumatoid arthritis: Subgroup analyses of a global phase 3 study (FINCH 2)
  Tsutomu Takeuchi, Tsukasa Matsubara, Tatsuya Atsumi, Koichi Amano, Naoki Ishiguro, Eiji Sugiyama, Kunihiro Yamaoka, Mark C. Genovese, Kenneth C. Kalunian, David H. Wal...> ;Modern Rheumatology. 2021 Jan 18
• 62 citations
  Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior expo...
  Rene Westhovens, William F. C. Rigby, Désirée van der Heijde, Daniel W. T Ching, William Stohl, Jonathan Kay, Arvind Chopra, Beatrix Bartok, Franziska Matzkies, Z. Yin...> ;Annals of the Rheumatic Diseases. 2021 Jun 1
• 178 citations
  Effect of Filgotinib vs Placebo on Clinical Response in Patients with Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therap...
  Mark C. Genovese, Kenneth C. Kalunian, Jacques-Eric Gottenberg, Neelufar Mozaffarian, Beatrix Bartok, Franziska Matzkies, Jie Gao, Ying Guo, Chantal Tasset, John S. Su...> ;JAMA. 2019 Jul 23
• 32 citations
  PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes.
  Corr, M. P., Angel Bottini, Dennis J. Wu, Rizi Ai, Michelle Le Roux, Beatrix Bartok, Michele Bombardieri, Karen M. Doody, Vida Zhang, Cristiano Sacchetti, Martina Zocc...> ;Annals of the Rheumatic Diseases. 2019 May 1
• 30 citations
  TGFβ responsive tyrosine phosphatase promotes rheumatoid synovial fibroblast invasiveness
  Stephanie M. Stanford, German R Aleman Muench, Beatrix Bartok, Cristiano Sacchetti, William B. Kiosses, Jay Sharma, Michael F. Maestre, Massimo Bottini, Tomas Mustelin...> ;Annals of the Rheumatic Diseases. 2016 Jan 1
• 1 citations
  Correction: Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic Targets.
  John W. Whitaker, David L. Boyle, Beatrix Bartok, Scott T. Ball, Wei Wang, Gary S. Firestein> ;Plos One. 2015 Aug 19
• 42 citations
  Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy.
  Corr, M. P., Karen M. Doody, Stephanie M. Stanford, Cristiano Sacchetti, Mattias Svensson, C.H. Coles, Nikolaos Mitakidis, William B. Kiosses, Beatrix Bartok, Camille ...> ;Science Translational Medicine. 2015 May 20
• 37 citations
  Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic Targets
  John W. Whitaker, David L. Boyle, Beatrix Bartok, Scott T. Ball, Wei Wang, Gary S. Firestein> ;Plos One. 2015 Apr 22
• 26 citations
  Differential Distribution of PI3K Isoforms in Spinal Cord and Dorsal Root Ganglia: Potential Roles in Acute Inflammatory Pain
  Mathias Leinders, Fred J. Koehrn, Beatrix Bartok, David L. Boyle, Veronica I. Shubayev, Iveta Kalcheva, Nam-Kyung Yu, Jihye Park, Bong-Kiun Kaang, Michael P. Hefferan,...> ;Pain. 2014 Jun 1
• 28 citations
  Novel Phosphoinositide 3-Kinase δ,γ Inhibitor: Potent Anti-Inflammatory Effects and Joint Protection in Models of Rheumatoid Arthritis
  David L. Boyle, Hae-Rim Kim, Katharyn Topolewski, Beatrix Bartok, Gary S. Firestein> ;The Journal of Pharmacology and Experimental Therapeutics. 2014 Feb 1
• 56 citations
  Phosphoinositide 3-Kinase δ Regulates Migration and Invasion of Synoviocytes in Rheumatoid Arthritis
  Beatrix Bartok, Deepa Hammaker, Gary S. Firestein> ;Journal of Immunology. 2014 Jan 27
• 41 citations
  Protein Tyrosine Phosphatase Expression Profile of Rheumatoid Arthritis Fibroblast‐like Synoviocytes: A Novel Role of SH2 Domain–Containing Phosphatase 2 as a Modulato...
  Stephanie M. Stanford, Michael F. Maestre, Amanda M. Campbell, Beatrix Bartok, William B. Kiosses, David L. Boyle, Heather A. Arnett, Tomas Mustelin, Gary S. Firestein...> ;Arthritis and Rheumatism. 2013 May 1
• 84 citations
  PI3 kinase δ is a key regulator of synoviocyte function in rheumatoid arthritis.
  Beatrix Bartok, David L. Boyle, Yi Liu, Pingda Ren, Scott T. Ball, William D. Bugbee, Christian Rommel, Gary S. Firestein> ;The American Journal of Pathology. 2012 May 1
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