
Gary S Firestein MD
Distinguished Professor, Medicine, UCSD School of Medicine
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200 W Arbor DrSan Diego, CA 92103
Phone+1 858-822-0480
Fax+1 858-534-2606
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Summary
- Gary Firestein, MD, is a rheumatologist based in San Diego, CA, specializing in mixed connective tissue disease and arthritis. He completed his medical education at Johns Hopkins University School of Medicine, followed by an internship in Internal Medicine at UCLA and a fellowship in Rheumatology at the University of California (San Diego) Medical Center. Dr. Firestein has several publications, including recent articles in Biorxiv, Nature Reviews Rheumatology, and The New England Journal of Medicine, with research focused on rheumatoid arthritis. He is recognized as a Master of the American College of Rheumatology and has been elected to prestigious organizations such as the American Association for the Advancement of Science and the Association of American Physicians.
Education & Training
University of California (San Diego) Medical CenterFellowship, Rheumatology, 1983 - 1986
UCLA David Geffen School of Medicine/UCLA Medical CenterInternship, Internal Medicine, 1980 - 1981
Johns Hopkins University School of MedicineClass of 1980
Certifications & Licensure
CA State Medical License 1982 - 2027
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Rheumatology
Awards, Honors, & Recognition
- Elected member American Association for the Advancement of Science (AAAS), 2021
- Elected Master American College of Rheumatology, 2021
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2012-2015
Publications & Presentations
PubMed
- Senescent-like activated naive B cells contribute to progression to clinical rheumatoid arthritis.Xiaohao Wu, Mengrui Zhang, Jae-Seung Moon, Eun Kyung Song, Joshua C Abrams
Nature Aging. 2026-10-01 - Low-Dose Interleukin-2 Enhances Activated Suppressor Regulatory T Cells and CTLA-4 and HLA-DR Expression in Chronic Chikungunya Arthritis.Sarah R Tritsch, Jose Forero Mejia, Evelyn Mendoza-Torres, Alfonso Sucerquia, Abebawork Adem
Pathogens. 2026-07-22 - 2 citationsAssociation of Epigenetic Trajectory With Development of Clinical Rheumatoid Arthritis in Individuals With Anti-Citrullinated Protein Antibody Positivity: Targeting Im...E Barton Prideaux, David L Boyle, Eunice Choi, Jane H Buckner, William H Robinson
Arthritis & Rheumatology. 2026-04-22
Journal Articles
- Reply to Letter to the EditorGary L Simon, Gary S Firestein, Aileen Y Chang, Arthritis & Rheumatology
- Reply to Comments on “The Frequency of Chronic Joint Pain Following Chikungunya Virus Infection A Colombian Cohort Study”Gary S Firestein, Gary L Simon, Aileen Y Chang, Arthritis & Rheumatology
- Methods for High-Dimensonal Analysis of Cells Dissociated from Cyropreserved Synovial TissuePaul J Utz, William H Robinson, Ellen M Gravallese, Soumya Raychaudhuri, Alessandra B Pernis, Susan M Goodman, Michael B Brenner, Lionel B Ivashkiv, Brendan F Boyce, P..., BioMed Central
Lectures
- American College of Rheumatology (ACR): Winter Rheumatology SymposiumAmerican College of Rheumatology(ACR), Snowmass, Colorado - 1/26/2013
Other
- Pathogenesis of rheumatoid arthritisFirestein GS, Schur PH
http://www.uptodate.com/contents/pathogenesis-of-rheumatoid-arthritis
UpToDate, Wolters Kluwer Health - 2012-09-11
Press Mentions
RA Begins Long Before Symptoms Appear – Seven-Year US StudyDecember 3rd, 2025
New Study Shows Rheumatoid Arthritis Begins Long Before SymptomsNovember 26th, 2025
Early Rheumatoid Arthritis Studies Redefine Prevention and Clinical ResearchNovember 19th, 2025
Grant Support
- Rheumatic Diseases Research Training GrantUNIVERSITY OF CALIFORNIA, SAN DIEGO2013–2029
- Methotrexate treatment of Arthritis caused by Chikungunya virus (MARCH): A randomized controlled trial of methotrexate versus placebo in the treatment of chronic arthritis after chikungunya infectionGEORGE WASHINGTON UNIVERSITY2022–2028
- Methotrexate treatment of Arthritis caused by Chikungunya virus (MARCH): A randomized controlled trial of methotrexate versus placebo in the treatment of chronic arthritis after chikungunya infectionGEORGE WASHINGTON UNIVERSITY2022–2028
- UC San Diego Clinical and Translational Research InstituteUNIVERSITY OF CALIFORNIA, SAN DIEGO2015–2025
- UC San Diego Clinical and Translational Research InstituteUNIVERSITY OF CALIFORNIA, SAN DIEGO2015–2025
Professional Memberships
- Fellow
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