BenjaminDanMatthewsMD

Pediatrics • Boston, MA

Pediatric Critical Care Medicine

Assistant Professor of Pediatrics, Boston Children's Hospital

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Office
300 Longwood Ave
Boston, MA 02115
Phone+1 617-355-6000
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Education & Training

Zucker School of Medicine at Hofstra/Northwell at Cohen Children's Medical CenterResidency, Pediatrics, 1991 - 1994
McGill University Faculty of MedicineClass of 1991

Certifications & Licensure

MA State Medical License 1999 - 2024
American Board of Pediatrics Pediatric Critical Care Medicine

Publications & Presentations

PubMed

4 citations
The Prominin-1-Derived Peptide Improves Cardiac Function Following Ischemia.
Avner Adini, Irit Adini, Etty Grad, Yuval Tal, Haim D. Danenberg, Peter M. Kang, Benjamin D. Matthews, Robert J. D'Amato> ;International Journal of Molecular Sciences. 2021 May 13
10 citations
PR1P Stabilizes VEGF and Upregulates Its Signaling to Reduce Elastase-induced Murine Emphysema.
Avner Adini, Hao Wu, Duy T. Dao, Victoria H. Ko, Lumeng J. Yu, Amy Pan, Mark Puder, Selome Z Mitiku, Ratnakar Potla, Hong Chen, James M Rice, Benjamin D. Matthews> ;American Journal of Respiratory Cell and Molecular Biology. 2020 Oct 1
5 citations
Molecular mapping of transmembrane mechanotransduction through the β1 integrin-CD98hc-TRPV4 axis.
Ratnakar Potla, Mariko Hirano-Kobayashi, Hao Wu, Hong Chen, Akiko Mammoto, Benjamin D Matthews, Donald E Ingber> ;Journal of Cell Science. 2020 Nov 2
19 citations
AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage.
Juan Li, Amy M. Wen, Ratnakar Potla, Ezekiel Benshirim, Ariel Seebarran, Maximilian A. Benz, Olivier Y.F. Henry, Benjamin D. Matthews, Rachelle Prantil-Baun, Sarah E. ...> ;APL Bioengineering. 2019 Dec 2
27 citations
Feasibility Pilot Study of a Teaching Kitchen and Self-Care Curriculum in a Workplace Setting
David Eisenberg, Allison C. Righter, Benjamin D. Matthews, Weimin Zhang, Walter C. Willett, Jennifer Massa> ;American Journal of Lifestyle Medicine. 2019 May 1
43 citations
Pregnancy and parental leave among obstetrics and gynecology residents: results of a nationwide survey of program directors.
Eduardo Hariton, Benjamin D. Matthews, Abigail Burns, Chitra Akileswaran, Lori R. Berkowitz> ;American Journal of Obstetrics and Gynecology. 2018 Apr 16
35 citations
A novel strategy to enhance angiogenesis in vivo using the small VEGF-binding peptide PR1P
Avner Adini, Irit Adini, Zai-Long Chi, Ratmir Derda, Amy E. Birsner, Benjamin D. Matthews, Robert J. D'Amato> ;Angiogenesis. 2017 Apr 10
19 citations
Prevention of ventilator-induced lung edema by inhalation of nanoparticles releasing ruthenium red.
Samuel Jurek, Mariko Hirano-Kobayashi, Homer Chiang, Daniel S. Kohane, Benjamin D. Matthews> ;American Journal of Respiratory Cell and Molecular Biology. 2014 Jun 1
Molecular gas clumps from the destruction of icy bodies in the β Pictoris debris disk.
Dent WRF, Wyatt MC, Roberge A, Augereau J, Casassus S, Corder S, Greaves JS, de Gregorio-Monsalvo I, Hales A, Jackson AP, Hughes AM, Lagrange A, Matthews B, Wilner D> ;Science. 2014-03-28
13 citations
Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin α6β1-ADAM17/tumor necrosis factor-α-converting enzyme (TACE) signaling pa...
Yulian Wang, Zheping Huang, Pritha S. Nayak, Benjamin D. Matthews, David Warburton, Wei Shi, Juan Sanchez-Esteban> ;The Journal of Biological Chemistry. 2013 Aug 30
572 citations
A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice
Dongeun Huh, Daniel C. Leslie, Benjamin D. Matthews, Jacob P. Fraser, Samuel Jurek, Geraldine A. Hamilton, Kevin S. Thorneloe, Michael Allen McAlexander, Donald E. Ingber> ;Science Translational Medicine. 2012 Nov 7
291 citations
Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels
Netanel Korin, Mathumai Kanapathipillai, Benjamin D. Matthews, Marilena Crescente, Alexander Brill, Tadanori Mammoto, Kaustabh Ghosh, Samuel Jurek, Sidi A. Bencherif, ...> ;Science. 2012 Aug 10
85 citations
Rapamycin Suppresses Self-Renewal and Vasculogenic Potential of Stem Cells Isolated from Infantile Hemangioma
Shoshana Greenberger, Siming Yuan, Logan A. Walsh, Elisa Boscolo, Kyu-Tae Kang, Benjamin D. Matthews, John B. Mulliken, Joyce Bischoff> ;The Journal of Investigative Dermatology. 2011 Dec 1
186 citations
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface β1 integrins
Benjamin D. Matthews, Charles K. Thodeti, Jessica D. Tytell, Akiko Mammoto, Darryl R. Overby, Donald E. Ingber> ;Integrative Biology. 2010 Sep 1
2147 citations
Reconstituting Organ-Level Lung Functions on a Chip
Dongeun Huh, Benjamin D. Matthews, Akiko Mammoto, Martin Montoya-Zavala, Hong Yuan Hsin, Donald E. Ingber> ;Science. 2010 Jun 25
259 citations
TRPV4 Channels Mediate Cyclic Strain–Induced Endothelial Cell Reorientation Through Integrin-to-Integrin Signaling
Charles K. Thodeti, Benjamin D. Matthews, Arvind Ravi, Akiko Mammoto, Kaustabh Ghosh, Abigail L. Bracha, Donald E. Ingber> ;Circulation Research. 2009 May 8
21 citations
Wheeze detection in the pediatric intensive care unit: comparison among physician, nurses, respiratory therapists, and a computerized respiratory sound monitor.
Reynaldo S Dela Rosa, Maria Shubina, Kenan Haver, Benjamin D. Matthews, Sarah Buck, Robert M. Kacmarek, Natan Noviski, Parthak Prodhan> ;Respiratory Care. 2008 Oct 1
59 citations
Rheological Behavior of Living Cells Is Timescale-Dependent
Dimitrije Stamenović, Noah J. Rosenblatt, Martin Montoya-Zavala, Benjamin D. Matthews, Shaohua Hu, Béla Suki, Ning Wang, Donald E. Ingber> ;Biophysical Journal. 2007 Oct 15
94 citations
α-Actinin-4 Is Required for Normal Podocyte Adhesion
Savita V. Dandapani, Hikaru Sugimoto, Benjamin D. Matthews, Robert J. Kolb, Sumita Sinha, Robert E. Gerszten, Jing Zhou, Donald E. Ingber, Raghu Kalluri, Martin R. Pollak> ;The Journal of Biological Chemistry. 2007 Jan 5
41 citations
Tools to study cell mechanics and mechanotransduction.
Tanmay P. Lele, Julia E. Sero, Benjamin D. Matthews, Sanjay Kumar, Shannon Xia, Martin Montoya-Zavala, Thomas R. Polte, Darryl R. Overby, Ning Wang, Donald E. Ingber> ;Methods in Cell Biology. 2007 Jan 1
323 citations
Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels
Benjamin D. Matthews, Darryl R. Overby, Robert Mannix, Donald E. Ingber> ;Journal of Cell Science. 2006 Feb 1
69 citations
α4β1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the α4-cytoplasmic domain
Ronen Alon, Sara W. Feigelson, Eugenia Manevich, David M. Rose, Julia Schmitz, Darryl R. Overby, Eitan Winter, Valentin Grabovsky, Vera Shinder, Benjamin D. Matthews, ...> ;The Journal of Cell Biology. 2005 Dec 19
38 citations
Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry.
Darryl R. Overby, Benjamin D. Matthews, Eben Alsberg, Donald E. Ingber> ;Acta Biomaterialia. 2005 May 1
82 citations
Mechanical properties of individual focal adhesions probed with a magnetic microneedle.
Benjamin D. Matthews, Darryl R. Overby, Francis J. Alenghat, John Karavitis, Yasuchi Numaguchi, Philip G. Allen, Donald E. Ingber> ;Biochemical and Biophysical Research Communications. 2004 Jan 16
13 citations
Management of oxygenation in pediatric acute hypoxemic respiratory failure.
Benjamin D. Matthews, Natan Noviski> ;Pediatric Pulmonology. 2001 Dec 1
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Hospital Affiliations

Boston Children's HospitalBoston, Massachusetts