BrianToddEdelsonMD

PubMed

• 3 citations
  Antigen-guided depletion of anti-HLA antibody-producing cells by HLA-Fc fusion proteins.
  Ashlee M Webber, Tara R Bradstreet, Xiaoli Wang, Hongjie Guo, Christopher A Nelson, Daved H Fremont, Brian T Edelson, Chang Liu> ;Blood. 2022 Oct 20
• 4 citations
  Mesothelium-Derived Factors Shape GATA6-Positive Large Cavity Macrophages.
  Chin-Wen Lai, Prachi Bagadia, Derek A G Barisas, Nicholas N Jarjour, Rachel Wong, Takahiro Ohara, Brian D Muegge, Qiuhe Lu, Shanshan Xiong, Brian T Edelson, Kenneth M ...> ;Journal of Immunology. 2022 Aug 15
• 8 citations
  BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy.
  Avery J Salmon, Alexander S Shavkunov, Qi Miao, Nicholas N Jarjour, Sunita Keshari, Ekaterina Esaulova, Charmelle D Williams, Jeffrey P Ward, Anna M Highsmith, Josué E...> ;Cancer Immunology Research. 2022 May 3
• 11 citations
  CD11c+CD88+CD317+ myeloid cells are critical mediators of persistent CNS autoimmunity
  Navid Manouchehri, Rehana Z. Hussain, Petra D. Cravens, Ekaterina Esaulova, Maxim N. Artyomov, Brian T. Edelson, Gregory F. Wu, Anne H. Cross, Richard Doelger, Nicolas...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Apr 6
• 14 citations
  Standardized Uptake Value for 18F-Fluorodeoxyglucose Is a Marker of Inflammatory State and Immune Infiltrate in Cervical Cancer
  John M. Floberg, Jin Zhang, Naoshad Muhammad, Todd A. DeWees, Matthew Inkman, Kevin Chen, Alexander J. Lin, Ramachandran Rashmi, Kay Jayachandran, Brian T. Edelson, Ba...> ;Clinical Cancer Research. 2021 Apr 5
• 52 citations
  Transcription Factor Bhlhe40 in Immunity and Autoimmunity.
  Melissa E. Cook, Nicholas N. Jarjour, Chih-Chung Lin, Brian T. Edelson> ;Trends in Immunology. 2020 Nov 1
• 50 citations
  Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation.
  Ekaterina Esaulova, Claudia Cantoni, Irina Shchukina, Konstantin Zaitsev, Robert C. Bucelli, Gregory F. Wu, Maxim N. Artyomov, Anne H. Cross, Brian T. Edelson> ;Neurology(R) Neuroimmunology & Neuroinflammation. 2020 Jul 1
• 16 citations
  BHLHE40 Promotes TH2 Cell-Mediated Antihelminth Immunity and Reveals Cooperative CSF2RB Family Cytokines.
  Nicholas N. Jarjour, Tara R. Bradstreet, Elizabeth A. Schwarzkopf, Melissa E. Cook, Chin-Wen Lai, Stanley Ching-Cheng Huang, Reshma Taneja, Thaddeus S. Stappenbeck, St...> ;Journal of Immunology. 2020 Feb 15
• 68 citations
  Erratum: The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality (Immunity (2019) 51(3) (491–507.e7), (S10...
  Chaofan Li, Bibo Zhu, Young Min Son, Zheng Wang, Li Jiang, Min Xiang, Zhenqing Ye, Kathryn E. Beckermann, Yue Wu, James Jenkins, Peter J. Siska, Benjamin G. Vincent, Y...> ;Immunity. 2020 Jan 14
• 27 citations
  Pathogenic Bhlhe40+ GM-CSF+ CD4+ T Cells Promote Indirect Alloantigen Presentation in the GI Tract During GVHD
  Clint Piper, Vivian X. Zhou, Richard A. Komorowski, Aniko Szabo, Benjamin G. Vincent, Jonathan S. Serody, Maria-Luisa Alegre, Brian T. Edelson, Reshma Taneja, William ...> ;Blood. 2020 Feb 20
• 62 citations
  The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8T Cell Fitness and Functionality.
  Chaofan Li, Bibo Zhu, Young Min Son, Zheng Wang, Li Jiang, Min Xiang, Zhenqing Ye, Kathryn E Beckermann, Yue Wu, James W Jenkins, Peter J Siska, Benjamin G Vincent, Y ...> ;Immunity. 2019 Sep 17
• 51 citations
  Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity
  Nicholas N. Jarjour, Elizabeth A. Schwarzkopf, Tara R. Bradstreet, Irina Shchukina, Chih-Chung Lin, Stanley Ching-Cheng Huang, Chin-Wen Lai, Melissa E. Cook, Reshma Ta...> ;Nature Immunology. 2019 May 6
• 77 citations
  Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity.
  Nan Zhang, Rafael S. Czepielewski, Nicholas N. Jarjour, Emma C. Erlich, Ekaterina Esaulova, Brian Saunders, Steven P. Grover, Audrey C. A. Cleuren, George J. Broze, Br...> ;The Journal of Experimental Medicine. 2019 Jun 3
• 74 citations
  Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection.
  Jeremy P. Huynh, Chih-Chung Lin, Jacqueline M. Kimmey, Nicholas N. Jarjour, Elizabeth A. Schwarzkopf, Tara R. Bradstreet, Irina Shchukina, Oleg Shpynov, Casey T. Weave...> ;The Journal of Experimental Medicine. 2018 Jul 2
• 19 citations
  Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer.
  Anshu P. Gounder, Christine C. Yokoyama, Nicholas N. Jarjour, Traci L. Bricker, Brian T. Edelson, Adrianus C. M. Boon> ;Plos Pathogens. 2018 Apr 26
• 159 citations
  Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection.
  Sharmila Nair, Jeremy P. Huynh, Vicky Lampropoulou, Ekaterina Loginicheva, Ekaterina Esaulova, Anshu P. Gounder, Adrianus C. M. Boon, Elizabeth A. Schwarzkopf, Tara R....> ;The Journal of Experimental Medicine. 2018 Apr 2
• 61 citations
  OTUD4 Is a Phospho-Activated K63 Deubiquitinase that Regulates MyD88-Dependent Signaling
  Yu Zhao, Miranda C. Mudge, Jennifer M. Soll, Rachel B. Rodrigues, Andrea K. Byrum, Elizabeth A. Schwarzkopf, Tara R. Bradstreet, Steven P. Gygi, Brian T. Edelson, Nima...> ;Molecular Cell. 2018 Feb 1
• 34 citations
  A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages
  Abigail J Morales, Javier A. Carrero, Putzer J Hung, Anthony T. Tubbs, Jared M. Andrews, Brian T. Edelson, Boris Calderon, Cynthia L. Innes, Richard S. Paules, Jacquel...> ;Elife. 2017 Mar 31
• 94 citations
  New Insights into the Role of IL-1β in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis.
  Chih-Chung Lin, Brian T. Edelson> ;Journal of Immunology. 2017 Jun 15
• 891 citations
  Mitochondrial Dynamics Controls T Cell Fate Through Metabolic Programming
  Michael D. Buck, David O’Sullivan, Ramon I. Klein Geltink, Jonathan D. Curtis, Chih-Hao Chang, David E. Sanin, Jing Qiu, Oliver Kretz, Daniel Braas, Gerritje J.W. van ...> ;Cell. 2016 Jun 30
• 64 citations
  IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation
  Chih-Chung Lin, Tara R. Bradstreet, Elizabeth A. Schwarzkopf, Nicholas N. Jarjour, Chun Chou, Angela S. Archambault, Julia Sim, Bernd H. Zinselmeyer, Javier A. Carrero...> ;The Journal of Experimental Medicine. 2016 Feb 8
• 83 citations
  Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12
  Bart Everts, Roxane Tussiwand, Leentje Dreesen, Keke C. Fairfax, Stanley Ching-Cheng Huang, Amber M. Smith, Christina M. O’Neill, Wing Y. Lam, Brian T. Edelson, Joseph...> ;The Journal of Experimental Medicine. 2016 Jan 11
• 57 citations
  Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection
  Donna A. MacDuff, Tiffany A. Reese, Jacqueline M. Kimmey, Leslie A. Weiss, Christina Song, Xin Zhang, Amal Kambal, Erning Duan, Javier A. Carrero, Bertrand Boisson, Em...> ;Elife. 2015 Jan 20
• 72 citations
  c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells
  Chun Chou, Amelia K. Pinto, Jonathan D. Curtis, Stephen P. Persaud, Marina Cella, Chih-Chung Lin, Brian T. Edelson, Paul M. Allen, Marco Colonna, Erika L. Pearce, Mich...> ;Nature Immunology. 2014 Jul 13
• 39 citations
  CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection
  Victor S. Cortez, Luisa Cervantes-Barragan, Christina Song, Susan Gilfillan, Keely G. McDonald, Roxane Tussiwand, Brian T. Edelson, Yoshinori Murakami, Kenneth M. Murp...> ;The Journal of Experimental Medicine. 2014 Apr 7
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Lectures

• A Bhlhe40/GM-CSF Axis Potentiates Gastrointestinal Tract Inflammation during Acute Graft Versus Host Disease 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018