BrianHansenLadleMDPhD

PubMed

• Impact of Consolidative Radiation on Overall and Progression-Free Survival in Pediatric, Adolescent, and Young Adult Metastatic Bone and Soft Tissue Sarcoma.
  Leslie Chang, Anjali D'Amiano, Rohini Bhatia, Gayane Yenokyan, Nicolas J Llosa, Brian H Ladle, Christian F Meyer, Adam S Levin, Christine A Pratilas, Matthew Ladra, Sa...> ;International Journal of Radiation Oncology, Biology, Physics. 2024 Feb 1
• Complex/crypticGene Fusions and 1q Jumping Translocation in Pediatric Ewing Sarcomas.
  Ying S Zou, Laura Morsberger, Melanie Hardy, Jen Ghabrial, Victoria Stinnett, Jaclyn B Murry, Patty Long, Andrew Kim, Christine A Pratilas, Nicolas J Llosa, Brian H La...> ;Genes. 2023 May 24
• 2 citations
  Gut colonization with an obesity-associated enteropathogenic microbe modulates the premetastatic niches to promote breast cancer lung and liver metastasis.
  Sheetal Parida, Sumit Siddharth, Himavanth R Gatla, Shaoguang Wu, Guannan Wang, Kathleen Gabrielson, Cynthia L Sears, Brian H Ladle, Dipali Sharma> ;Frontiers in Immunology. 2023 Jan 1
• Adoptive Cellular Therapy for Pediatric Solid Tumors: Beyond Chimeric Antigen Receptor-T Cell Therapy.
  Jonathan Hensel, Jonathan Metts, Ajay Gupta, Brian H Ladle, Shari Pilon-Thomas, John Mullinax> ;Cancer Journal. 2022 Jul 26
• 12 citations
  Exceptional response to the ALK and ROS1 inhibitor lorlatinib and subsequent mechanism of resistance in relapsed ALK F1174L-mutated neuroblastoma.
  Tingting Liu, Matthew D. Merguerian, Steven P. Rowe, Christine A. Pratilas, Allen R. Chen, Brian H. Ladle> ;Cold Spring Harbor Molecular Case Studies. 2021 Aug 1
• 40 citations
  Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes
  John A. Ligon, Woonyoung Choi, Gady Cojocaru, Wei Fu, Emily Han-Chung Hsiue, Teniola Oke, Nicholas Siegel, Megan H. Fong, Brian H. Ladle, Christine A. Pratilas, Carol ...> ;Journal for Immunotherapy of Cancer. 2021 May 1
• 5 citations
  Predictors of Recurrence and Patterns of Initial Failure in Localized Ewing Sarcoma: A Contemporary 20-Year Experience.
  Gregory C. Stachelek, John A. Ligon, Jennifer Vogel, Adam S. Levin, Nicolas J. Llosa, Brian H. Ladle, Christian F. Meyer, Stephanie A. Terezakis, Carol D. Morris, Matt...> ;Sarcoma. 2021 Apr 17
• 1 citations
  Moving Toward the Ideal Autologous Adoptive T-cell Therapy for Cancer.
  Brian H. Ladle> ;Cancer Research. 2021 Apr 15
• 17 citations
  Neoantigen-based EpiGVAX vaccine initiates antitumor immunity in colorectal cancer
  Victoria M. Kim, Xingyi Pan, Kevin C. Soares, Nilofer S. Azad, Nita Ahuja, Christopher Gamper, Alex B. Blair, Stephen Muth, Ding Ding, Brian H. Ladle, Lei Zheng> ;JCI Insight. 2020 May 7
• 40 citations
  The Immunosuppressive Niche of Soft-Tissue Sarcomas is Sustained by Tumor-Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid Structures
  Lingling Chen, Teniola Oke, Nicholas Siegel, Gady Cojocaru, Ada J. Tam, Richard L. Blosser, Jessica Swailes, John A. Ligon, Andriana Lebid, Carol D. Morris, Adam S. Le...> ;Clinical Cancer Research. 2020 Aug 1
• 15 citations
  T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate
  Kun-Po Li, Brian H. Ladle, Sema Kurtulus, Allyson Sholl, Sharmila Shanmuganad, David A. Hildeman> ;Cell Death and Differentiation. 2020 Apr 1
• 89 citations
  De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation.
  Brian H. Ladle, Kun-Po Li, Maggie J. Phillips, Alexandra B. Pucsek, Azeb Haile, Jonathan D. Powell, Elizabeth M. Jaffee, David A. Hildeman, Christopher Gamper> ;Proceedings of the National Academy of Sciences of the United States of America. 2016 Sep 20
• 53 citations
  De novo DNA methylation is required to restrict T helper lineage plasticity
  Rajan M. Thomas, Christopher Gamper, Brian H. Ladle, Jonathan D. Powell, Andrew D. Wells> ;The Journal of Biological Chemistry. 2012 Jun 29
• 19 citations
  CD8⁺ Foxp3⁺ tumor infiltrating lymphocytes accumulate in the context of an effective anti-tumor response.
  Dung T. Le, Brian H. Ladle, Timothy C. Lee, Vivian L. Weiss, Xiaosai Yao, Ashley Leubner, Todd D. Armstrong, Elizabeth M. Jaffee> ;International Journal of Cancer. 2011 Aug 1
• 81 citations
  OX40 Costimulation Synergizes with GM-CSF Whole-Cell Vaccination to Overcome Established CD8+ T Cell Tolerance to an Endogenous Tumor Antigen
  Satoshi Murata, Brian H. Ladle, Peter S. Kim, Eric R. Lutz, Matthew E. Wolpoe, Susan E. Ivie, Holly M. Smith, Todd D. Armstrong, Leisha A. Emens, Elizabeth M. Jaffee, ...> ;Journal of Immunology. 2006 Jan 15
• 315 citations
  Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response.
  Anne M. Ercolini, Brian H. Ladle, Elizabeth A. Manning, Lukas W. Pfannenstiel, Todd D. Armstrong, Jean-Pascal Machiels, Joan G. Bieler, Leisha A. Emens, R. Todd Reilly...> ;The Journal of Experimental Medicine. 2005 May 16
• Join now to see all