ChalliceBonifantMDPhD

PubMed

• Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors.
  Adrian C Johnston, Gretchen M Alicea, Cameron C Lee, Payal V Patel, Eban A Hanna, Eduarda Vaz, André Forjaz, Zeqi Wan, Praful R Nair, Yeongseo Lim, Tina Chen, Wenxuan ...> ;Biorxiv. 2024 Mar 26
• Longitudinal plasma proteomics in CAR T-cell therapy patients implicates neutrophils and NETosis in the genesis of CRS.
  Christopher Flora, Mary Olesnavich, Yu Zuo, Erin Sandford, Rashmi Madhukar, Michelle Rozwadowski, Kavya Sugur, Andrew Ly, Ata Alpay Canbaz, Audra Shedeck, Gen Li, Marc...> ;Blood Advances. 2024 Mar 26
• 1 citations
  HLH-like toxicities predict poor survival after the use of tisagenlecleucel in children and young adults with B-ALL.
  Kevin O McNerney, Stephanie J Si Lim, Kyle Ishikawa, Alexandra Dreyzin, Anant Vatsayan, John J Chen, Christina Baggott, Snehit Prabhu, Holly L Pacenta, Christine Phili...> ;Blood Advances. 2023 Jun 27
• 1 citations
  The rapid and highly parallel identification of antibodies with defined biological activities by SLISY.
  Steve Lu, Austin K Mattox, P Aitana Azurmendi, Ilias Christodoulou, Katharine M Wright, Maria Popoli, Zan Chen, Surojit Sur, Yana Li, Challice L Bonifant, Chetan Bette...> ;Nature Communications. 2023 Jan 3
• Mediport use as an acceptable standard for CAR T cell infusion.
  Toner, K. N., Maya Eylon, Snehit Prabhu, Samuel John, Maxwell J M King, Dhruv Bhatt, Kevin J Curran, Courtney Erickson, Nicole A Karras, Christine L Phillips, Prakash ...> ;Frontiers in Immunology. 2023 Jan 1
• 9 citations
  Novel banana lectin CAR-T cells to target pancreatic tumors and tumor-associated stroma.
  Mary K McKenna, Ada Ozcan, Daniel Brenner, Norihiro Watanabe, Maureen Legendre, Dafydd G Thomas, Christopher Ashwood, Richard D Cummings, Challice Bonifant, David M Ma...> ;Journal for Immunotherapy of Cancer. 2023 Jan 1
• 2 citations
  CCRL2 affects the sensitivity of myelodysplastic syndrome and secondary acute myeloid leukemia cells to azacitidine.
  Theodoros Karantanos, Patric Teodorescu, Marios Arvanitis, Brandy Perkins, Tania Jain, Amy E DeZern, W Brian Dalton, Ilias Christodoulou, Bogdan C Paun, Ravi Varadhan,...> ;Haematologica. 2023 Jul 1
• 12 citations
  Targeting glycans for CAR therapy: The advent of sweet CARs.
  Zoe Raglow, Mary Kathryn McKenna, Challice L Bonifant, Wenjing Wang, Marina Pasca di Magliano, Johannes Stadlmann, Josef M Penninger, Richard D Cummings, David M Marko...> ;Molecular Therapy. 2022 Sep 7
• 1 citations
  Gene-Based Natural Killer Cell Therapies for the Treatment of Pediatric Hematologic Malignancies.
  Ruyan Rahnama, Ilias Christodoulou, Challice L Bonifant> ;Hematology/oncology Clinics of North America. 2022 Aug 1
• 5 citations
  Improving the anti-acute myeloid leukemia activity of CD123-specific engager T cells by MyD88 and CD40 costimulation.
  Abishek Vaidya, Erin Doherty, Xiya Wu, Sujuan Huang, Nikhil Hebbar, Unmesha Thanekar, Challice L Bonifant, Cheng Cheng, Stephen Gottschalk, Velasquez, P., Velasquez, P...> ;Haematologica. 2023 Apr 1
• 7 citations
  The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia.
  Theodoros Karantanos, Patric Teodorescu, Ilias Christodoulou, Christopher Esteb, Ravi Varadhan, Eric Helmenstine, Trivikram Rajkhowa, Bogdan C Paun, Challice Bonifant,...> ;Science Advances. 2022 Feb 18
• 17 citations
  Impact of High Disease Burden on Survival in Pediatric Patients with B-ALL Treated with Tisagenlecleucel.
  Jonas W Ravich, Sujuan Huang, Yinmei Zhou, Patrick Brown, Ching-Hon Pui, Hiroto Inaba, Cheng Cheng, Stephen Gottschalk, Brandon M Triplett, Challice L Bonifant, Aimee ...> ;Transplantation and Cellular Therapy. 2022 Feb 1
• 6 citations
  Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models.
  Hong Mu-Mosley, Lauren Ostermann, Muharrem Muftuoglu, Abishek Vaidya, Challice L Bonifant, Mireya Paulina Velasquez, Stephen Gottschalk, Michael Andreeff> ;Frontiers in Immunology. 2022 Jan 1
• 49 citations
  Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities.
  Ilias Christodoulou, Won Jin Ho, Andrew Marple, Jonas W Ravich, Ada Tam, Ruyan Rahnama, Adam Fearnow, Cambrynne Rietberg, Sean Yanik, Elena E Solomou, Ravi Varadhan, M...> ;Journal for Immunotherapy of Cancer. 2021 Dec 1
• 5 citations
  Intravenous anakinra for tisagenlecleucel-related toxicities in children and young adults.
  Alexandra Dreyzin, David A. Jacobsohn, Anne L. Angiolillo, Birte Wistinghausen, Reuven J. Schore, Evelio Perez, Elizabeth Wells, Joshua Terao, Challice L. Bonifant, Ra...> ;Pediatric Hematology and Oncology. 2021 Oct 21
• 9 citations
  High risk of relapsed disease in patients with NK/T cell chronic active Epstein-Barr virus disease outside of Asia.
  Blachy J. Dávila Saldaña, Tami D John, Challice L. Bonifant, David Buchbinder, Sharat Chandra, Shanmuganathan Chandrakasan, Weni Chang, Leon Chen, Hannah L Elfassy, As...> ;Blood Advances. 2021 Oct 20
• 6 citations
  Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis
  Michael A. Koldobskiy, Garrett Jenkinson, Jordi Abante, Varenka A. Rodriguez DiBlasi, Weiqiang Zhou, Elisabet Pujadas, Adrian Idrizi, Rakel Tryggvadottir, Colin M. Cal...> ;Nature Biomedical Engineering. 2021 Apr 15
• 10 citations
  Glycoprotein Targeted CAR-NK Cells for the Treatment of SARS-CoV-2 Infection.
  Ilias Christodoulou, Ruyan Rahnama, Jonas W Ravich, Jaesung Seo, Sergey N Zolov, Andrew N Marple, David M Markovitz, Challice L Bonifant> ;Frontiers in Immunology. 2021 Jan 1
• 12 citations
  The Art and Science of Selecting a CD123-Specific Chimeric Antigen Receptor for Clinical Testing
  Janice M. Riberdy, Sheng Zhou, Fei Zheng, Young In Kim, Jennifer Moore, Abishek Vaidya, Robert E. Throm, April Sykes, Natasha Sahr, Challice L. Bonifant, Byoung Y. Ryu...> ;Molecular Therapy. Methods & Clinical Development. 2020 Sep 11
• 13 citations
  Improving CAR T-cells: The next generation.
  Andrew H. Marple, Challice L. Bonifant, Nirali N. Shah> ;Seminars in Hematology. 2020 Jul 23
• 14 citations
  The future of cellular immunotherapy for childhood leukemia.
  Challice L. Bonifant, Sarah K. Tasian> ;Current Opinion in Pediatrics. 2020 Feb 1
• 10 citations
  T-cell Activity against AML Improved by Dual-Targeted T Cells Stimulated through T-cell and IL7 Receptors
  Eric Krawczyk, Sergey N. Zolov, Kevin Y. Huang, Challice L. Bonifant> ;Cancer Immunology Research. 2019 Apr 1
• 52 citations
  Programmed cell death protein 1 activation preferentially inhibits CD28.CAR-T cells.
  Sergey N. Zolov, Skyler P. Rietberg, Challice L. Bonifant> ;Cytotherapy. 2018 Oct 1
• 13 citations
  Advances in immunotherapy for pediatric acute myeloid leukemia.
  Challice L. Bonifant, Mireya Paulina Velasquez, Stephen Gottschalk> ;Expert Opinion on Biological Therapy. 2018 Jan 2
• 2 citations
  Work efficiency improvement of >90% after implementation of an annual inpatient blood products administration consent form
  Holly L. Lindsay, Saleh Bhar, Challice L. Bonifant, Sarah E. Sartain, Sarah B. Whittle, YoungNa Lee-Kim, Mona D. Shah> ;BMJ Open Quality. 2018 Jan 1
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Abstracts/Posters

• Transgenic Expression of IL15 in CD123-Specific BiTE-Secreting Engager T-Cells Results in Improved Anti-AML Activity
  Challice L. Bonifant, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Inducible MyD88 Signaling Enhances the Anti-AML Activity of BiTE-Secreting ENG T-Cells
  Challice L. Bonifant, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019