Yang-YangDingMD

PubMed

• 1 citations
  Identification and targeting of treatment resistant progenitor populations in T-cell Acute Lymphoblastic Leukemia.
  Kai Tan, Jason Xu, Changya Chen, Tiffaney Vincent, Petri Pölönen, Jianzhong Hu, Satoshi Yoshimura, Wenbao Yu, Jonathan Sussman, Chia-Hui Chen, Elizabeth Li, Caroline D...> ;Research Square. 2023 Oct 30
• 30 citations
  Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia.
  Changya Chen, Wenbao Yu, Fatemeh Alikarami, Qi Qiu, Chia-Hui Chen, Jennifer Flournoy, Peng Gao, Yasin Uzun, Li Fang, James W Davenport, Yuxuan Hu, Qin Zhu, Kai Wang, C...> ;Blood. 2022 Apr 7
• 4 citations
  Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome-like Acute Lymphoblastic Leukemia
  Yang-Yang Ding, Hannah Kim, Kellyn Madden, Joseph P. Loftus, Gregory M. Chen, David Hottman Allen, Ruitao Zhang, Jason Xu, Chia-hui Chen, Yuxuan Hu, Sarah K. Tasian, K...> ;Clinical Cancer Research. 2021 Jul 1
• 65 citations
  Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy.
  Gregory M. Chen, Changya Chen, Rajat K. Das, Peng Gao, Chia-hui Chen, Shovik Bandyopadhyay, Yang-Yang Ding, Yasin Uzun, Wenbao Yu, Qin Zhu, Regina M. Myers, Stephan A....> ;Cancer Discovery. 2021 Apr 5
• 55 citations
  Delayed cancer diagnoses and high mortality in children during the COVID-19 pandemic.
  Yang-Yang Ding, Sneha Ramakrishna, Adrienne H. Long, Charles A. Phillips, Raul Montiel-Esparza, Caroline Diorio, L. Charles Bailey, Shannon L. Maude, Richard Aplenc, V...> ;Pediatric Blood & Cancer. 2020 Sep 1
• 11 citations
  Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers.
  Bing He, Peng Gao, Yang-Yang Ding, Chia-hui Chen, Gregory M. Chen, Changya Chen, Hannah Kim, Sarah K. Tasian, Stephen P. Hunger, Kai Tan> ;Science Advances. 2020 Jul 1
• 13 citations
  Dissecting the tumor-immune landscape in chimeric antigen receptor T-cell therapy: key challenges and opportunities for a systems immunology approach
  Gregory M. Chen, Andrew Azzam, Yang-Yang Ding, David M. Barrett, Stephan A. Grupp, Kai Tan> ;Clinical Cancer Research. 2020 Mar 3
• 23 citations
  Optimal control nodes in disease-perturbed networks as targets for combination therapy.
  Yuxuan Hu, Chia-hui Chen, Yang-Yang Ding, Xiao Wen, Bingbo Wang, Lin Gao, Kai Tan> ;Nature Communications. 2019 May 16
• 41 citations
  The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution
  Deanne Taylor, Bruce J. Aronow, Kai Tan, Kathrin M. Bernt, Nathan Salomonis, Casey S. Greene, Alina Frolova, Sarah E. Henrickson, Andrew D. Wells, Liming Pei, Jyoti K....> ;Developmental Cell. 2019 Apr 8
• 44 citations
  Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure.
  Yang Y. Ding, Julie W. Stern, Tracey Jubelirer, Gerald Wertheim, Fumin Lin, Fengqi Chang, Zhaohui Gu, Charles G. Mullighan, Yong Li, Richard C. Harvey, I-Ming Chen, Ch...> ;Haematologica. 2018 Sep 1
• 16 citations
  Transverse myelitis as an unexpected complication following treatment with dinutuximab in pediatric patients with high-risk neuroblastoma: A case series.
  Yang-Yang Ding, Jessica A. Panzer, John M. Maris, Alicia Castañeda, Marta Gomez-Chiari, Jaume Mora> ;Pediatric Blood & Cancer. 2018 Jan 1
• 3 citations
  Concordance of copy number alterations using a common analytic pipeline for genome-wide analysis of Illumina and Affymetrix genotyping data: a report from the Children...
  Marijana Vujkovic, Edward F. Attiyeh, Rhonda E. Ries, Michelle Horn, Elizabeth K. Goodman, Yang Ding, Marko Kavcic, Todd A. Alonzo, Robert B. Gerbing, Betsy A. Hirsch,...> ;Cancer Genetics. 2015 Jul 1
• 15 citations
  Genomic architecture and treatment outcome in pediatric acute myeloid leukemia: a Children’s Oncology Group report
  Marijana Vujkovic, Edward F. Attiyeh, Rhonda E. Ries, Elizabeth K. Goodman, Yang Ding, Marko Kavcic, Todd A. Alonzo, Yi-Cheng Wang, Robert B. Gerbing, Lillian Sung, Be...> ;Blood. 2017 Jun 8
• 61 citations
  Functional Role of BLAP75 in BLM-Topoisomerase IIIα-dependent Holliday Junction Processing
  Steven Raynard, Weixing Zhao, Wendy Bussen, Lucy Lu, Yang-Yang Ding, Valeria Busygina, Amom Ruhikanta Meetei, Patrick Sung> ;The Journal of Biological Chemistry. 2008 Jun 6
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Journal Articles

• Optimal control nodes in disease-perturbed networks as targets for combination therapy  
  Hu, Yuxuan; Chen, Chia-hui; Ding, Yang-yang; Wen, Xiao; Wang, Bingbo; Gao, Lin; Tan, Kai, Nature Communications, 5/16/2019