
Brian Thomas Layden MD PhD
Diabetes, Lipid Metabolism
Associate Professor, Division Chief
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1801 W Taylor StChicago, IL 60612
Phone+1 312-413-3631
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Clinical Expertise
- Diabetes mellitus, Obesity and obesity-related disorders, Insulin resistance, Adrenal disease
Education & Training
McGaw Medical Center of Northwestern UniversityFellowship, Endocrinology, Diabetes, and Metabolism, 2007 - 2010
McGaw Medical Center of Northwestern UniversityResidency, Internal Medicine, 2005 - 2007
University of Illinois College of MedicineClass of 2005
Certifications & Licensure
IL State Medical License 2008 - 2029
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification Northwestern Meaningful Use Data Warehouse Application for Eligible Providers, Northwestern University, 2012-2014, 2017
- CMS Meaningful Use Stage 1 Certification PowerChart, Cerner Corporation, 2012-2014, 2017
- CMS Meaningful Use Stage 2 Certification PowerChart (Clinical), Cerner Corporation, 2012-2014, 2017
Publications & Presentations
PubMed
- Type 2 diabetes-associated gut microbial composition and short chain fatty acids differ across the epidemiologic transition in African origin populations.Larske M Soepnel, Julianne A Jorgensen, Luke Hannan, Candice Choo-Kang, Asanda Mtintsilana
Gut Microbes Reports. 2027-01-01 - Weight-Loss Outcomes After Sleeve Gastrectomy Versus Tirzepatide in a Minority Cohort With Severe Obesity: Results From a Propensity Score Matched Cohort.Emiliano G Manueli Laos, Andres Fontaine-Nicola, Bianca Serafica, Lily Zhang, Brian T Layden
Clinical Obesity. 2026-12-01 - Prediction of Type 2 Diabetes Mellitus From Chest X-Rays Using a Suite of Previously Developed Chronic Disease Deep Learning Models in an Ethnically Diverse Cohort: Ob...Pola Lydia Lagari, Awais Farooq, Brian Thomas Layden, Ayis Pyrros, William Galanter
JMIR AI. 2026-07-03
Journal Articles
- Risk of Amputations Associated with SGLT2 Inhibitors Compared to DPP‐4 Inhibitors: A Propensity‐Matched Cohort StudyGregory S Calip, Brian T Layden, Diabetes, Obesity and Metabolism
- Role of Short Chain Fatty Acid Receptors in Intestinal Physiology and PathophysiologyBrian T. Layden, Brian T. Layden, Wiley
- Gut Microbiota: FFAR Reaching Effects on IsletsBrian Layden, MD, Endocrinology
Press Mentions
New Study Helps Understand Role of Gut Microbiome in Gestational DiabetesJanuary 27th, 2022
Researchers Investigate the Role of Arsenic in the Development of DiabetesMarch 11th, 2019
Diabetes Awareness, Treatment Need Big Push Among MinoritiesApril 13th, 2017
Grant Support
- Mechanisms of diabetes from acute pancreatitisUNIVERSITY OF ILLINOIS AT CHICAGO2020–2030
- Engineering In Vitro Models of Pregnancy-Induced Liver ChangesUNIVERSITY OF ILLINOIS AT CHICAGO2025–2027
- METS-Sleep: Sleep timing, gut microbiota and cardiometabolic risk across the Epidemiologic TransitionLOYOLA UNIVERSITY CHICAGO2019–2025
- Role of Nutrient Sensing Receptors for the Gut Microbiota in MetabolismJESSE BROWN VA MEDICAL CENTER2017–2025
- The function and regulation of the novel pregnancy-specific hexokinase HKDC1UNIVERSITY OF ILLINOIS AT CHICAGO2015–2025
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