BruceAlderBuckinghamMD

Pediatric Endocrinology • Palo Alto, CA

Pediatric Diabetes Endocrinology

Professor, Stanford Medical Center

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Office
730 Welch Rd
Palo Alto, CA 94304
Phone+1 650-804-0476

Fax+1 650-725-8375
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Summary

Dr. Bruce Buckingham is a pediatric endocrinologist in Palo Alto, CA and is affiliated with multiple hospitals in the area, including Lucile Packard Children's Hospital Stanford and Stanford Health Care. He received his medical degree from University of California San Diego School of Medicine and has been in practice 45 years. He specializes in automated insulin delivery systems for type 1 diabetes.

Education & Training

Children's Hospital Los AngelesFellowship, Pediatric Endocrinology, 1974 - 1976
Children's Hospital Los AngelesResidency, Pediatrics, 1972 - 1976
University of California San Diego School of MedicineClass of 1972

Certifications & Licensure

CA State Medical License 1973 - 2026
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Endocrinology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Pilot Study to Evaluate a Method of Controlling High Blood Sugar in the Pediatric Intensive Care Unit Start of enrollment: 2005 Oct 01
Completed
Not Applicable
Reversal of Hypoglycemia Unawareness Using Continuous Glucose Monitoring Start of enrollment: 2009 Mar 01
Withdrawn
Not Applicable
Development of Algorithms for a Hypoglycemic Prevention Alarm: Closed Loop Study Start of enrollment: 2007 May 01
Completed
Not Applicable
A Randomized Control Trial Comparing Linjeta Versus Humalog in Pumps: Effect on Postprandial Blood Sugars. Start of enrollment: 2010 Apr 01
Withdrawn
Phase 2
Duration of Infusion Set Function: Quick-Set Teflon Catheter Versus Sure-T Steel Infusion Set Catheter Start of enrollment: 2011 Jan 01
Completed
Not Applicable
Medtronic Treat to Range (TTR) Closed-Loop Control Start of enrollment: 2011 Dec 01
Completed
Not Applicable
Outpatient Pump Shutoff Pilot Feasibility and Efficacy Study Start of enrollment: 2012 Nov 01
Completed
Phase 2
Testing State of the Art Remote Glucose Monitoring at Diabetes Camp Start of enrollment: 2012 May 01
Completed
Not Applicable
An Outpatient Pump Shutoff Pilot Feasibility and Safety Study Start of enrollment: 2012 Jan 01
Completed
Phase 2
Outpatient Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension in Children Start of enrollment: 2013 May 01
Completed
Phase 2
Medtronic Minimed Overnight Closed-Loop System Start of enrollment: 2013 Jun 01
Completed
Not Applicable
Diabetes Assistant (DiAs) Control-to-Range (CTR) Nocturnal Closed-Loop Camp Study Start of enrollment: 2013 Jul 01
Completed
Not Applicable
Accelerometer Use in the Prevention of Exercise-Associated Hypoglycemia in Type 1 Diabetes: Outpatient Exercise Protocol Start of enrollment: 2014 Mar 12
Completed
Not Applicable
In Clinic Evaluation of the PLGM Feature Start of enrollment: 2014 Oct 01
Completed
Not Applicable
Pilot Study 3 of Outpatient Control-to-Range: Safety and Efficacy With Day-and-Night In-Home Use Start of enrollment: 2014 Aug 01
Completed
Not Applicable
Full Day and Night Closed-Loop With DiAs Platform Start of enrollment: 2014 May 01
Completed
Not Applicable
Hyaluronidase Effect on Infusion Set Life Start of enrollment: 2014 Jul 01
Completed
Phase 1
Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing in Children and Young Adolescents Start of enrollment: 2016 May 01
Completed
Phase 2
Initiation of Continuous Glucose Monitoring at Diagnosis of Type 1 Diabetes Start of enrollment: 2016 Feb 01
Completed
Not Applicable
Remote Monitoring of Diabetes in Young Children With Type 1 Diabetes Start of enrollment: 2016 Aug 15
Completed
Not Applicable
Day and Night Closed-loop in Young People With Type 1 Diabetes Start of enrollment: 2017 May 12
Completed
Not Applicable
The International Diabetes Closed Loop (iDCL) Trial: Protocol 1 Start of enrollment: 2017 Oct 27
Completed
Not Applicable
Insulet Artificial Pancreas Evaluating Meal Performance and Moderate Exercise (IDE2) Start of enrollment: 2017 Mar 18
Completed
Not Applicable
Glucose Response of G-Pen (Glucagon Injection) in Pediatric T1D Patients Start of enrollment: 2017 Mar 27
Completed
Phase 3
Efficacy of inControl Advice: A Decision Support System (DSS) for Diabetes Start of enrollment: 2017 Apr 17
Completed
Not Applicable
Longevity of Multi-Slitted Catheter With Lantern Technology Start of enrollment: 2019 Jan 25
Completed
Not Applicable
Real-time Reminders To Decrease Late or Missed Meal Boluses Start of enrollment: 2018 Oct 12
Completed
Not Applicable
The Pediatric Artificial Pancreas (PEDAP) Trial of Control-IQ Technology in Young Children in Type 1 Diabetes Start of enrollment: 2021 Apr 21
Completed
Not Applicable
Automated Insulin Delivery for INpatients With DysGlycemia (AIDING) Feasibility Start of enrollment: 2021 Jun 29
Completed
Not Applicable
Roles: Contact
The Pediatric Artificial Pancreas Automated Initialization Trial Start of enrollment: 2023 Nov 10
Recruiting
Not Applicable
Roles: Contact
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Publications & Presentations

PubMed

Decreasing the Burden of Carbohydrate Counting and Meal Announcement with Automated Insulin Delivery, Meal Recognition, and Autocorrection Doses: A Case Study.
Bergenstal, R., Buckingham, B.> ;Diabetes Technology & Therapeutics. 2024 Mar 1
2 citations
Diabetic Ketoacidosis at Diagnosis in Youth with Type 1 Diabetes Is Associated with a Higher Hemoglobin A1c Even with Intensive Insulin Management.
Dessi P Zaharieva, Ananta Addala, Priya Prahalad, Franziska Bishop, Manisha Desai, Darrell M Wilson, David M Maahs, Victoria Y Ding, Korey K Hood, Bruce A Buckingham> ;Diabetes Technology & Therapeutics. 2024 Mar 1
1 citations
Glycemic Outcomes Persist for up to 2 Years in Very Young Children with the Omnipod5 Automated Insulin Delivery System.
Sherr, J., Ly, T., DeSalvo, D., Forlenza, G., Schoelwer, M., MacLeish, S., Bode, B., Laffel, L., Criego, A., Hansen, D., Buckingham, B.> ;Diabetes Technology & Therapeutics. 2024 Feb 21
Patient reported outcomes (PROs) and user experiences of young children with type 1 diabetes using t:slim X2 insulin pump with control-IQ technology.
Korey K Hood, Aika K Schneider-Utaka, Zachariah W Reed, Bruce A Buckingham, Erin Cobry, Mark D DeBoer, Laya Ekhlaspour, Melissa Schoelwer, R Paul Wadwa, John Lum, Crai...> ;Diabetes Research and Clinical Practice. 2024 Feb 1
2 citations
Two Years with a Tubeless Automated Insulin Delivery System: A Single-Arm Multicenter Trial in Children, Adolescents, and Adults with Type 1 Diabetes.
Amy B Criego, Anders L Carlson, Sue A Brown, Gregory P Forlenza, Bruce W Bode, Carol J Levy, David W Hansen, Irl B Hirsch, Richard M Bergenstal, Jennifer L Sherr, Sanj...> ;Diabetes Technology & Therapeutics. 2024 Jan 1
Digital Technology for Diabetes.
Hughes, M. S., Michael S Hughes, Ananta Addala, Bruce Buckingham> ;The New England Journal of Medicine. 2023 Nov 30
4 citations
Safety and Glycemic Outcomes During the MiniMedAdvanced Hybrid Closed-Loop System Pivotal Trial in Children and Adolescents with Type 1 Diabetes.
Catherine Pihoker, Dorothy I Shulman, Gregory P Forlenza, Kevin B Kaiserman, Jennifer L Sherr, James R Thrasher, Bruce A Buckingham, Mark S Kipnes, Bruce W Bode, Ander...> ;Diabetes Technology & Therapeutics. 2023 Nov 1
1 citations
Automated Insulin Delivery with Remote Real-Time Continuous Glucose Monitoring for Hospitalized Patients with Diabetes: A Multicenter, Single-Arm, Feasibility Trial.
Georgia M Davis, Michael S Hughes, Sue A Brown, Judy Sibayan, M Citlalli Perez-Guzman, Meaghan Stumpf, Zachary Thompson, Marina Basina, Ronak M Patel, Joi Hester, Amal...> ;Diabetes Technology & Therapeutics. 2023 Oct 1
1 citations
Verapamil and Pancreatic Beta Cell Function in Pediatric Type 1 Diabetes-Reply.
Gregory P Forlenza, Marcus S Schamberger, Bruce A Buckingham> ;JAMA. 2023 Jul 25
8 citations
Glycemic Outcomes During Early Use of the MiniMed™ 780G Advanced Hybrid Closed-Loop System with Guardian™ 4 Sensor.
Toni L Cordero, Zheng Dai, Arcelia Arrieta, Fang Niu, Melissa Vella, John Shin, Andrew S Rhinehart, Jennifer McVean, Scott W Lee, Robert H Slover, Gregory P Forlenza, ...> ;Diabetes Technology & Therapeutics. 2023 Sep 1
2 citations
Swimming With the Omnipod 5 Automated Insulin Delivery System: Connectivity in the Water.
Michael S Hughes, Ryan S Kingman, Liana Hsu, Rayhan A Lal, Bruce A Buckingham, Dessi P Zaharieva> ;Diabetes Care. 2023 Aug 1
5 citations
Practical Aspects and Exercise Safety Benefits of Automated Insulin Delivery Systems in Type 1 Diabetes.
Dessi P Zaharieva, Dale Morrison, Barbora Paldus, Rayhan A Lal, Bruce A Buckingham, David N O'Neal> ;Diabetes Spectrum. 2023 May 1
14 citations
A Meta-Analysis of Randomized Trial Outcomes for the t:slim X2 Insulin Pump with Control-IQ Technology in Youth and Adults from Age 2 to 72.
Roy W Beck, Lauren G Kanapka, Marc D Breton, Sue A Brown, R Paul Wadwa, Bruce A Buckingham, Craig Kollman, Boris Kovatchev> ;Diabetes Technology & Therapeutics. 2023 May 1
16 citations
Trial of Hybrid Closed-Loop Control in Young Children with Type 1 Diabetes.
R Paul Wadwa, Zachariah W Reed, Bruce A Buckingham, Mark D DeBoer, Laya Ekhlaspour, Gregory P Forlenza, Melissa Schoelwer, John Lum, Craig Kollman, Roy W Beck, Marc D ...> ;The New England Journal of Medicine. 2023 Mar 16
86 citations
Continuous glucose monitoring and metrics for clinical trials: an international consensus statement.
Tadej Battelino, Charles M Alexander, Stephanie A Amiel, Guillermo Arreaza-Rubin, Roy W Beck, Richard M Bergenstal, Bruce A Buckingham, James Carroll, Antonio Ceriello...> ;The Lancet. Diabetes & Endocrinology. 2023 Jan 1
10 citations
ISPAD Clinical Practice Consensus Guidelines 2022: Other complications and associated conditions in children and adolescents with type 1 diabetes.
Elke Fröhlich-Reiterer, Nancy S Elbarbary, Kimber Simmons, Bruce Buckingham, Khadija N Humayun, Jesper Johannsen, Reinhard W Holl, Shana Betz, Farid H Mahmud> ;Pediatric Diabetes. 2022 Dec 1
18 citations
Positive Impact of the Bionic Pancreas on Diabetes Control in Youth 6-17 Years Old with Type 1 Diabetes: A Multicenter Randomized Trial.
Laurel H Messer, Bruce A Buckingham, Fran Cogen, Mark Daniels, Greg Forlenza, Rabab Z Jafri, Nelly Mauras, Andrew Muir, R Paul Wadwa, Perrin C White, Steven J Russell,...> ;Diabetes Technology & Therapeutics. 2022 Oct 1
77 citations
Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice.
Moshe Phillip, Revital Nimri, Richard M Bergenstal, Katharine Barnard-Kelly, Thomas Danne, Roman Hovorka, Boris P Kovatchev, Laurel H Messer, Christopher G Parkin, Lou...> ;Endocrine Reviews. 2023 Mar 4
12 citations
Evaluation of Extended Infusion Set Performance in Adults with Type 1 Diabetes: Infusion Set Survival Rate and Glycemic Outcomes from a Pivotal Trial.
Ron Brazg, Satish K Garg, Anuj Bhargava, James R Thrasher, Kashif Latif, Bruce W Bode, Timothy S Bailey, Barry S Horowitz, Arvind Cavale, Yogish C Kudva, Kevin B Kaise...> ;Diabetes Technology & Therapeutics. 2022 Aug 1
5 citations
Smartwatch gesture-based meal reminders improve glycaemic control.
John P Corbett, Liana Hsu, Sue A Brown, Laura Kollar, Katelijn Vleugels, Bruce Buckingham, Marc D Breton, Rayhan A Lal> ;Diabetes, Obesity & Metabolism. 2022 Aug 1
17 citations
Glycemic Outcomes in Baseline Hemoglobin A1C Subgroups in the International Diabetes Closed-Loop Trial.
Laya Ekhlaspour, Marissa Town, Dan Raghinaru, John W Lum, Sue A Brown, Bruce A Buckingham> ;Diabetes Technology & Therapeutics. 2022 Aug 1
23 citations
Safety and Glycemic Outcomes With a Tubeless Automated Insulin Delivery System in Very Young Children With Type 1 Diabetes: A Single-Arm Multicenter Clinical Trial.
Jennifer L Sherr, Bruce W Bode, Gregory P Forlenza, Lori M Laffel, Melissa J Schoelwer, Bruce A Buckingham, Amy B Criego, Daniel J DeSalvo, Sarah A MacLeish, David W H...> ;Diabetes Care. 2022 Aug 1
6 citations
Outpatient Randomized Crossover Comparison of Zone Model Predictive Control Automated Insulin Delivery with Weekly Data Driven Adaptation Versus Sensor-Augmented Pump:...
Jordan E Pinsker, Eyal Dassau, Sunil Deshpande, Dan Raghinaru, Bruce A Buckingham, Yogish C Kudva, Lori M Laffel, Carol J Levy, Mei Mei Church, Hannah Desrochers, Laya...> ;Diabetes Technology & Therapeutics. 2022 Sep 1
Pharmacodynamics, pharmacokinetics, safety, and tolerability of a ready-to-use, room temperature, liquid stable glucagon administered via an autoinjector pen to youth ...
Bruce Buckingham, Jennifer Sherr, Steven J Prestrelski, Valentina Conoscenti> ;Pediatric Diabetes. 2022 Sep 1
32 citations
Glycemic outcomes of children 2-6 years of age with type 1 diabetes during the pediatric MiniMed™ 670G system trial.
Gregory P Forlenza, Laya Ekhlaspour, Linda A DiMeglio, Larry A Fox, Henry Rodriguez, Dorothy I Shulman, Kevin B Kaiserman, David R Liljenquist, John Shin, Scott W Lee,...> ;Pediatric Diabetes. 2022 May 1
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Lectures

Effect of Lipohypertrophy on Dexcom G4p Continuous Glucose Sensor
Stanford, CA - 6/15/2014
Effect of Shared Medical Appointments in Youth with Type 1 Diabetes in Poor Control
Stanford, CA - 6/14/2014

Press Mentions

A Bionic Pancreas Aims to Take the Math Out of Managing Type 1 DiabetesSeptember 28th, 2022
At ADA, JDRF-Funded Research Takes Center Stage (With a “Happy Hour” by Dr. Aaron Kowalski)June 21st, 2022
Artificial Pancreases Were a Breakthrough for Type 1 Diabetes. The Research in Type 2 Is Just BeginningAugust 4th, 2021
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Grant Support

In Home Closed Loop Reduction Of Nocturnal Hypoglycemia And Daytime HyperglycemiaNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2011
Prevention Of Nocturnal Hypoglycemia: Effect On Neurologic Outcome In ToddlersEunice Kennedy Shriver National Institute Of Child Health &Human Development2007–2011
Development Of Algorithms For A Prototype Closed Loop Insulin PUMPNational Center For Research Resources2008
Clinical Trial: Hypoglycemia And The Accuracy Of Continuous Glucose Monitors InNational Center For Research Resources2008
Clinical Trial: Efficacy Of Continuous Glucose Monitoring In The Management Of TNational Center For Research Resources2008
Navigator: Glucose Sensor In The Management Of Type-1 Diabetes In ChildrenNational Center For Research Resources2006
Development Of Hypoglycemia In Children With Type-1 DiabetesNational Center For Research Resources2006
Near-Continuous Glucose Monitoring In PediatricsEunice Kennedy Shriver National Institute Of Child Health &Human Development2002–2006
Pilot And Feasibility Study Of Novolog Pharmacodynamics In ToddlersNational Center For Research Resources2005
Development Of Hypoglycemia In Children With Type 1 DiabetesNational Center For Research Resources2005