BruceRTroenMD

PubMed

• Methionine adenosyltransferase2A inhibition restores metabolism to improve regenerative capacity and strength of aged skeletal muscle.
  Nika Rajabian, Izuagie Ikhapoh, Shahryar Shahini, Debanik Choudhury, Ramkumar Thiyagarajan, Aref Shahini, Joseph Kulczyk, Kendall Breed, Shilpashree Saha, Mohamed Alaa...> ;Nature Communications. 2023 Feb 16
• 1 citations
  Inhibition of glutaminolysis restores mitochondrial function in senescent stem cells.
  Debanik Choudhury, Na Rong, Izuagie Ikhapoh, Nika Rajabian, Georgios Tseropoulos, Yulun Wu, Pihu Mehrotra, Ramkumar Thiyagarajan, Aref Shahini, Kenneth L Seldeen, Bruc...> ;Cell Reports. 2022 Nov 29
• 44 citations
  World guidelines for falls prevention and management for older adults: a global initiative.
  Manuel Montero-Odasso, Nathalie van der Velde, Finbarr C Martin, Mirko Petrovic, Maw Pin Tan, Jesper Ryg, Sara Aguilar-Navarro, Neil B Alexander, Clemens Becker, Huber...> ;Age and Ageing. 2022 Sep 2
• Tristetraprolin limits age-related expansion of myeloid-derived suppressor cells.
  Kyu Hwan Kwack, Lixia Zhang, Elliot D Kramer, Ramkumar Thiyagarajan, Natalie A Lamb, Yukitomo Arao, Jonathan E Bard, Kenneth L Seldeen, Bruce R Troen, Perry J Blackshe...> ;Frontiers in Immunology. 2022 Jan 1
• 2 citations
  Leukotriene inhibitors with dexamethasone show promise in the prevention of death in COVID-19 patients with low oxygen saturations.
  Peter L Elkin, Skyler Resendez, Sarah Mullin, Bruce R Troen, Manoj J Mammen, Shirley Chang, Gillian Franklin, Wilmon McCray, Steven H Brown> ;Journal of Clinical and Translational Science. 2022 Jan 1
• 6 citations
  Ameliorating the hallmarks of cellular senescence in skeletal muscle myogenic progenitors in vitro and in vivo.
  Aref Shahini, Nika Rajabian, Debanik Choudhury, Shahryar Shahini, Kalyan Vydiam, Thy Nguyen, Joseph Kulczyk, Tyler Santarelli, Izuagie Attairu Ikhapoh, Yali Zhang, Jia...> ;Science Advances. 2021 Sep 3
• 7 citations
  Short-term nicotinamide riboside treatment improves muscle quality and function in mice and increases cellular energetics and differentiating capacity of myogenic prog...
  Kenneth L. Seldeen, Aref Shahini, Ramkumar Thiyagarajan, Yonas Redae, Merced M Leiker, Nika Rajabian, Andrew Dynka, Stelios T. Andreadis, Bruce R. Troen> ;Nutrition. 2021 Feb 8
• 2 citations
  Pinpointing a Role for Vitamin D in Frailty: A Time for Animal Models?
  Kenneth L. Seldeen, Bruce R. Troen> ;Advances in Geriatric Medicine and Research. 2021 Feb 6
• 11 citations
  The Association of Muscle Mass Measured by D3-Creatine Dilution Method With Dual-Energy X-Ray Absorptiometry and Physical Function in Postmenopausal Women.
  Kexin Zhu, Jean Wactawski-Wende, Heather M. Ochs-Balcom, Michael J. LaMonte, Kathleen M. Hovey, William J. Evans, Mahalakshmi Shankaran, Bruce R. Troen, Hailey R. Banack> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2021 Aug 13
• Falls: To D or Not to D—That Is Not the (Only) Question!
  Bruce R. Troen> ;Annals of Internal Medicine. 2021 Feb 1
• 10 citations
  Vitamin D Insufficiency Reduces Grip Strength, Grip Endurance and Increases Frailty in Aged C57Bl/6J Mice
  Kenneth L. Seldeen, Reem Nagi Berman, Manhui Pang, Ginger Lasky, Carleara Weiss, Brian Alexander MacDonald, Ramkumar Thiyagarajan, Yonas Redae, Bruce R. Troen> ;Nutrients. 2020 Sep 30
• 1 citations
  Absence of complement factor H reduces physical performance in C57BL6 mice.
  Kenneth L. Seldeen, Ramkumar Thiyagarajan, Yonas Redae, Alexander Jacob, Bruce R. Troen, Richard J. Quigg, Jessy J. Alexander> ;Immunobiology. 2020 Sep 1
• 8 citations
  AGS and NIA Bench‐to Bedside Conference Summary: Osteoporosis and Soft Tissue (Muscle and Fat) Disorders
  Cathleen S. Colón-Emeric, Heather E. Whitson, Sarah D. Berry, Roger A. Fielding, Denise K. Houston, Douglas P. Kiel, Clifford J. Rosen, Kenneth L. Seldeen, Elena Volpi...> ;Journal of the American Geriatrics Society. 2020 Jan 1
• 19 citations
  Investigating and Remediating Selection Bias in Geriatrics Research: The Selection Bias Toolkit
  Hailey R. Banack, Jay S. Kaufman, Jean Wactawski-Wende, Bruce R. Troen, Steven D. Stovitz> ;Journal of the American Geriatrics Society. 2019 Sep 1
• 10 citations
  High intensity interval training improves physical performance in aged female mice: A comparison of mouse frailty assessment tools
  Kenneth L. Seldeen, Yonas Redae, Ramkumar Thiyagarajan, Reem Nagi Berman, Merced M Leiker, Bruce R. Troen> ;Mechanisms of Ageing and Development. 2019 Jun 1
• 35 citations
  AP-1 and Mitf interact with NFATc1 to stimulate cathepsin K promoter activity in osteoclast precursors.
  Manhui Pang, Maria Rodríguez-Gonzalez, Mireya Hernandez, Claudia Carolina Recinos, Kenneth L. Seldeen, Bruce R. Troen> ;Journal of Cellular Biochemistry. 2019 Aug 1
• 13 citations
  Treatment with an inhibitor of fatty acid synthase attenuates bone loss in ovariectomized mice.
  Sandra Bermeo, Ahmed Al Saedi, Christopher Vidal, Mamdouh Khalil, Manhui Pang, Bruce R. Troen, Damian E. Myers, Gustavo Duque> ;Bone. 2019 May 1
• 3 citations
  Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice.
  Kenneth L. Seldeen, Yonas Redae, Ramkumar Thiyagarajan, Reem Nagi Berman, Merced M Leiker, Bruce R. Troen> ;Journal of Visualized Experiments. 2019 Feb 2
• 16 citations
  Myeloid-Derived Suppressor Cells at the Intersection of Inflammaging and Bone Fragility.
  Keith L. Kirkwood, Lixia Zhang, Ramkumar Thiyagarajan, Kenneth L. Seldeen, Bruce R. Troen> ;Immunological Investigations. 2018 Dec 18
• 8 citations
  Neuropeptide Y Y2 antagonist treated ovariectomized mice exhibit greater bone mineral density.
  Kenneth L. Seldeen, Paul Halley, Claude-Henry Volmar, Maria A. Navarro Rodriguez, M. Hernandez, Manhui Pang, S.K. Carlsson, Larry J. Suva, Claes Wahlestedt, Bruce R. T...> ;Neuropeptides. 2017 Nov 7
• 3 citations
  Absence of complement factor H alters bone architecture and dynamics.
  Jessy J. Alexander, Jeyantt S. Sankaran, Kenneth L. Seldeen, Ramkumar Thiyagarajan, Alexander Jacob, Richard J. Quigg, Bruce R. Troen, Stefan Judex> ;Immunobiology. 2018 Aug 1
• 9 citations
  Chronic vitamin D insufficiency impairs physical performance in C57BL/6J mice.
  Kenneth L. Seldeen, Manhui Pang, Merced M Leiker, Jonathan E. Bard, Maria Rodríguez-Gonzalez, Mireya Hernandez, Zachary Sheridan, Norma J. Nowak, Bruce R. Troen> ;Aging. 2018 Jun 1
• 19 citations
  Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway
  Anna Sharikova, Elizabeth Quaye, Jun Yong Park, Maxwell C. Maloney, Habben Desta, Ramkumar Thiyagarajan, Kenneth L. Seldeen, Neil U. Parikh, Parteet Sandhu, Alexander ...> ;Journal of Neuroimmune Pharmacology. 2018 Apr 11
• 49 citations
  High Intensity Interval Training Improves Physical Performance and Frailty in Aged Mice.
  Kenneth L. Seldeen, Ginger Lasky, Merced M Leiker, Manhui Pang, Kirkwood E. Personius, Bruce R. Troen> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2018 Mar 14
• 31 citations
  A mouse model of vitamin D insufficiency: is there a relationship between 25(OH) vitamin D levels and obesity?
  Kenneth L. Seldeen, Manhui Pang, Maria Rodríguez-Gonzalez, Mireya Hernandez, Zachary Sheridan, Ping Yu, Bruce R. Troen> ;Nutrition & Metabolism. 2017 Mar 11
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Journal Articles

• Treatment for osteoporosis in Australian residential aged care facilities: consensus recommendations for fracture prevention.  
  Duque G., Close J.J., de Jager J.P., Ebeling P.R., Inderjeeth C., Lord S., McLachlan A.J., Reid I.R., Troen B.R., Sambrook P.N, Med J Aust
• The cathepsin L gene is a direct target of FOXO1 in the skeletal muscle.  
  Yamazaki, Y., Kamei, Y., Sugita, S., Akaike, F., Kanai, S., Miura, S., Hirata, Y., Troen, B.R., Kitamura, T., Nishino, I., Suganami, T., Ezaki, O., Ogawa, Y, Biochem J
• Hypovitaminosis D in the elderly: from bone to brain.  
  Cherniack, E.P., Florez, H., Roos, B.A. Troen, B.R. and Levis, S, J Nutr Health Aging
• Molecular cloning, expression and function of osteoclastic calcineurin Aα.  
  Sun, L., Moonga, B.S., Lu, M., Iqbal, J., Inzerillo, A., Blair, H.C., Huang, C.H., Epstein, S., Abe, E., Troen, B.R., Zaidi, M, Am J Physiol Renal
• Differential effects of interleukin-6 receptor activation on intracellular signaling and bone resorption by isolated rat osteoclasts.  
  Moonga, B.S., Adebanjo, O.A. ,Wang, H-J., Sun, L., Wu, X.B., Troen, B., Inzerillo, A., Abe, E., Minkin, C., Huang, C.L., Zaidi, M, Journal of Endocrinology
• CD38/ADP-ribosyl cyclase: a new role in the regulation of osteoclastic bone resorption.  
  Sun, L., Adebanjo, O. A., Moonga, B.S., Corisdeo, S., Anandatheerthavarada, H.K, Biswas, G., Arakawa, T., Hakeda, Y., Koval, A., Sodam, B., Bevis, P.J.R., Moser, A.J...., J Cell Biol 146
• Cloning and expression of the gene for MEP. A secreted lysosomal protease regulated by transformation.  
  Troen, B.R., Ascherman, D., Atlas, D., Gottesman, M.M, J Biol Chem
• Effect of age on the 3,5,3’-tri-iodothyronine-induced increase in sugar uptake in rat thymocytes.  
  Segal, J. and Troen, B.R, J Endocrinol
• Studies of the human testis. III. Effect of estrogen on testosterone formation in human testis in vitro.  
  Yanaihara, T., Troen, P., Troen, B.R. and Troen, M.L, J Clin Endocrinol Metab
• Is the current anti-osteoporotic therapy paradigm good enough?  
  Troen, B.R, Response J Am Geriatr Soc
• AP-1 and Mitf Interact with NFATc1 to Stimulate Cathepsin K Promoter Activity in Osteoclast Precursors.  
  Pang, M., Balkan, W., Rodriguez, M., Hernandez, M., Troen, B.R, J Bone Miner Res
• Age Modifies the Impact of Vitamin D3 Supplementation on the 25-OH Vitamin D/ Parathyroid Hormone Ratio.  
  Florez, H.J., Cherniack, E. P., Gómez-Marín, O., Roos, B. A., Levis, S., Troen, B.R, J Bone Miner Res
• Age Is Inversely Correlated With Apolipoprotein C-III Levels In Elderly Men At Risk For Type 2 Diabetes.  
  Florez, H., Castillo-Florez, S., Casanova-Romero, P., Larreal, C., Goldberg, R., Troen, B.R, J Am Geriatr Soc
• Low Oxygen Tension Enhances Osteoclast-Like Cell Formation but not Resoprtion in RAW 264.  
  Pang, M., Troen, B.R, Cells J Bone Miner Res
• Obesity Increases Fracture Risk in Patients with Low Vitamin D.  
  Florez, H., Chacra, W., Martinez, R.E., Cherniack, E.P., Strickman-Stein, N., Roos, B.A., Troen, B.R. Levis, S, J Bone Miner Res
• RANK Ligand Stimulates Cathepsin K Gene Expression via NFAT2 Binding of the Promoter.  
  Martinez, A.F., Fernandez, I., Troen, B.R, J Bone Miner Res
• c-Jun Suppresses and JunB Enhances the Stimulation of Cathepsin K Promoter Activity by NFAT2 in RAW 264.  
  Troen, B.R., Martinez, A.F., Pang, M., Fernandez, I., Balkan, W, 7 Cells J Bone Miner Res
• A Transgenic Model To Study Osteoclast Differentiation During Osteoporosis.  
  Balkan, W., Pang, M., Fernandez, I., Martinez, A.F., Troen, B.R, J Am Geriatr Soc
• Frailty grip is associated with fasting hyperglycemia and obesity.  
  Florez, H., Garay, S.D., Castillo-Florez, S., Juan, A., Stein, N., Cherniack, E.P., Goldberg R. B., Troen, B.R, J Am Geriatr Soc
• Apo E Gene Polymorphism is Associated with Low HDL Cholesterol in Elderly Venezuelan Women.  
  Florez, H., Silva, E., Gonzalez, A., Sulbaran, T., Ryder, E., Troen, B., Maestre, G, J Am Geriatr Soc
• Bisphosphonate Effects on the Program of Gene Transcription During Osteoclastogenesis.  
  Sun, L., Gross, G., Varbanov, A., Phipps, R., Zaidi, M., Troen, B.R, J Bone Miner Res
• Cross-Talk Between RANKL and Interferon Gamma in the Regulation of Cathepsin Gene Transcription in Pre-Osteoclastic Cells.  
  Pang, M., Martinez, A. F., Jacobs,, J., Balkan, W., Troen, B.R, J Bone Miner Res
• Gender Differences in Reaching the Low Density Lipoprotein Cholesterol Level Targeted for the High Coronary Heart Disease Risk Category in Elderly Hispanic Patients ...  
  Florez, H., Sulbaran, T.. Silva, E., Calmon, G., Castillo-Florez, S., Ruiz, J., Troen, B., Rodriguez, O., Samos, F.L., Goldberg, R., Roos, B.A, J Am Geriatr Soc
• Clinical and Metabolic Risk Factors Associated with Elevated Fasting Plasma Glucose in Elderly Hispanic Patients from Zulia State, Venezuela.  
  Florez, H., Sulbaran, T.. Silva, E., Calmon, G., Castillo-Florez, S., Ruiz, J., Troen, B., Rodriguez, O., Samos, F.L., Roos, B.A., Goldberg, R, J Am Geriatr Soc
• Estrogen Inhibits Cathepsin K Gene Expression in Osteoclasts Via the JNK/AP-1 Signal Transduction Pathway.  
  Dolgilevich, S., Liu, B., Zhao, J., Troen, B.R, J Am Geriatr Soc
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Books/Book Chapters

• Vitamin D, cognitive function, and mental health. 
  Chapter: Lifetime nutritional influences on cognition, behaviour and psychiatric illness 
  Page 420 - 432Cherniack, E.P. and Troen, B.REditors: Benton, D.Cambridge, UK: Woodhead Publishing, Ltd
• Cell and Molecular Aging. 
  Chapter: Principles and Practice of Geriatric Surgery 
  Page 5 - 38Rai, P. and Troen, B.REditors: Rosenthal, Zenilman, Katlic.Springer Verlag, New YorkEdition 2nd,
• Osteoporosis. 
  Chapter: Hazzard's Principles of Geriatric Medicine and Gerontology 
  Page 1421 - 1434Duque, G. and Troen, B.REditors: Halter, Ouslander, Tinetti, Asthana, High, Studenski.McGraw-Hill, New YorkEdition 6th,
• Calciotropic Hormones. 
  Chapter: Senile Osteoporosis: Advances in Pathophysiology and Therapeutic Approach 
  Page 34 - 46Cherniack, E.P. and Troen, B.REditors: Duque, G. and Kiel, D.Springer-Verlag London Limited
• The Demographics of Aging in Women. 
  Chapter: The Menopause: Endocrinologic Basis & Management Options 
  Page 23 - 34Paniagua, M. and Troen, B.REditors: Eskin, B.A.Taylor and Francis, Boca Raton, FLEdition 6th,
• Skeletal Aging. 
  Chapter: Geriatric Nutrition: The Health Professional’s Handbook 
  Page 325 - 344Duque, G. and Troen, B.REditors: Chernoff.Jones and Bartlett, Boston, MAEdition 3rd,
• Biology of Aging, 2001 
  Chapter: Geriatrics Review Syllabus 
  Page 8 - 16Troen, B.R. and Jurivich, D.AEditors: Pompei, P. & Murphy, J.B.American Geriatrics Society, New YorkEdition 6th,
• Skeletal Fragility in the Elderly. 
  Chapter: Geriatric Medicine 
  Inzerillo, A., Iqbal, J., Meier, D., Troen, B.R., and Zaidi, MEditors: Cassel, Leipzig, Cohen, Larson, & Meier.Springer-Verlag, New YorkEdition 4th,
• Approach to the Geriatric Patient, 1998. 
  Chapter: The Geripause: Medical Management 
  Page 79 - 82Troen, B.REditors: Eskin & Troen.Parthenon, New York
• Geripause. 
  Chapter: The Geripause: Medical Management 
  Page 3 - 10Troen, B.REditors: Eskin & Troen.Parthenon, New York
• Osteoporosis. 
  Chapter: The Geripause: Medical Management 
  Page 135 - 150Troen, B.R., Inzerillo, A., Zaidi, MEditors: Eskin & Troen.Parthenon, New York
• Molecular and Clinical Pharmacology of Calcitonin. 
  Chapter: Principles of Bone Biology 
  Page 1423 - 1440Zaidi, M., Inzerillo, A.M., Troen, B. Moonga, B.S., Abe, E., and Burckhardt, PEditors: Bilezikian, Raisz, & Rodan.Academic Press, San Diego, CAEdition 2nd,
• Biological Mechanisms of Aging. 
  Chapter: Geriatrics Review Syllabus 
  Page 1 - 8Jurivich, D.A. and Troen, B.REditors: Cobbs, E.L, Duthie, E.H., & Murphy, J.B.Blackwell Publishing, Malden, MAEdition 5th,
• Cell and Molecular Aging. 
  Chapter: Principles and Practice of Geriatric Surgery 
  Page 8 - 23Troen, B.R. and Cristofalo, V.JEditors: Rosenthal, Zenilman, & Katlic.Springer-Verlag, New York
• The Geripause. 
  Chapter: The Menopause: Comprehensive Management 
  Page 23 - 32Troen, B.REditors: Eskin, B.A.The Parthenon Publishing Group, New YorkEdition 4th,
• Biological Mechanisms of Aging. 
  Chapter: Geriatrics Review Syllabus 
  Page 5 - 10Troen, B.R. and Cristofalo, V.JEditors: Cobbs, E.L, Duthie, E.H., & Murphy, J.B.Kendall/Hunt, Dubuque, IowaEdition 4th,
• The Gene Construction Kit: DNA Sequence Analysis and Presentation 
  Chapter: Sequence Data Analysis Guidebook 
  Troen, B.REditors: Swindell, S.Humana Press, New Jersey
• Expression of tissue proteinases and regulation of protein degradation as related to meat quality. 
  Chapter: Cathepsin genes: structure, expression and regulation. 
  Page 29 - 46Troen, B.REditors: Ouali, A., Demeyer, D.I., & Smulders, F.J.M.Audet Tijdschriften bv, Nijmegen, The Netherlands
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Abstracts/Posters

• Vitamin D supplementation reduces blood pressure in the elderly and this is modified by frailty.
  Florez, H.J., Apaza, A., Sosa-Melo, A., Cherniack, E. P., Levis, S., Troen, B.R., Roos, B. A, Gerontological Society of American Annual Meeting
• Sirtuin Activating Compounds Inhibit Reactive Oxygen Species and Osteoclastogenesis.
  Pang, M., Rodriguez-Gonzalez, M., Hernandez, M., Fernandez, I., Duque, G., Troen, B.R, Gerontological Society of American Annual Meeting
• Sirtuin Activating Compounds Inhibit Rac1 Activation, Actin Ring Formation, and Osteoclastogenesis.
  Pang, M., Hernandez, M., Fernandez, I., Rodriguez-Gonzalez, M., Troen, B.R, American Society for Bone and Mineral Research Annual Meeting
• Higher Vitamin D Requirements In Older Persons.
  Florez, H.J., Troen, B.R., Roos, B. A., Cherniack, E. P., Levis, S, American Society for Bone and Mineral Research Annual Meeting
• Relationship of Insulin Resistance and Metabolic Syndrome with Endothelial Progenitor Cells and Flow-Mediated Vasodilation.
  Montenegro, A., Salgueiro, L., Troen, B.R., Florez, H., Hurwitz, B, American Heart Association Annual Meeting
• Sirtuin activating compounds and aging bone, Keystone Symposium: New Insights into Healthspan and Diseases of Aging.
  Pang, M., Hernandez, M., Rodriguez-Gonzalez, M., Fernandez, I., Duque, G., Troen, B.R, Molecular to Functional Senescence
• Osteoprotegerin Ligand Stimulates Cathepsin K Gene Expression in Osteoclasts.
  Corisdeo, S., Gyda, M., Troen, B.R, P426 at the American Geriatrics Society Meeting
• IFN-γ Suppresses Cathepsin K Gene Transcription.
  Gyda, M., Jasti, S., Corisdeo, S., Troen, B.R, P36 at the American Geriatrics Society Meeting
• Regulation of cathepsin gene expression in promonocytes.
  Jain, V., Troen, B.R, the American Geriatrics Society Meeting
• Analysis of gene expression and senescence by differential display of the polymerase chain reaction.
  Lee, T., Troen, B.R, the American Geriatrics Society Meeting
• Expression of cathepsin L in human monocytes stimulated by phorbol esters.
  Chu, B., Troen, B.R, the American Geriatrics Society Meeting
• Molecular analysis of the MEP gene.
  Garber, J.E., Troen, B.R, the American Geriatrics Society Meeting
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Lectures

• Systolic Hypertension in the Elderly. 
  Geriatric Division Conference, University of Michigan Geriatric Division, Ann Arbor, MI
• Of Mice and Men: Cancer, Immunity and Bones. 
  Institute of Gerontology Faculty Business Seminars, University of Michigan, Ann Arbor, MI
• Healthspan and Frailty: Bedside to Benchtop (and Back?). 
  Division of Geriatrics, Boston University School of Medicine, Boston, MA
• Osteoporosis: Falls and Fracture Prevention. 
  Gerontological Advanced Practice Nurses Association (GAPNA) 31st Annual Conference
• Vitamin D: Beyond Skeletal Health - Implications for Frailty; 2005 - 2011. 
  Fifth Annual Interprofessional Geriatrics Symposium
• Vitamin D: Skeletal Health and Beyond (A Stealthy Epidemic), 2005 - 2011 
  American Geriatrics Society Annual Meeting, Washington, D.C
• Bone Biology during Aging: Impact on the Development of Osteoporosis and Subsequent Treatment Strategies - Understanding the RANK-RANKL-OPG Pathway and Its Importance... 
  American Geriatrics Society Annual Meeting, Washington, D.C
• New Advances In Osteoporosis Therapy In The Very Old, Frail, and Institutionalized Elderly: Reduction In Fractures and Improved Quality of Life. 
  American Geriatrics Society Annual Meeting, Washington, D.C
• Multidisciplinary Strategies For Preventing And Managing Osteoporosis In Frail High-Risk Elderly In Long-Term Care. 
  Gerontological Society of America Annual Meeting, New Orleans, LA
• Science of Aging Bone & Medical Management. 
  Gerontological Society of America Annual Meeting, New Orleans, LA
• Osteoporosis. 
  American Geriatrics Society Annual Meeting, Orlando, FL
• Prolongevity Compounds and Aging Bone. 
  Department of Medicine Research Conference, University of Texas Health Science Center at San Antoni
• Why do we grow old: perspectives on the biology of aging. 
  Keynote Speaker - Advancing the Science of Healthier Aging, American Federation for Aging Research
• Prolongevity Compounds and Aging Bone. 
  Advancing the Science of Healthier Aging, American Federation for Aging Research -Florida, Miami, FL
• Vitamin D and Osteoporosis, 2006 - 2008 
  VISN8 Ambulatory Care Forum
• Veterans Throughout the Ages: The Thread that Binds Them. 
  Miami, FL
• Osteoporosis in the Nursing Home: What is the best approach? 
  Term Care in Australia, Nepean Clinical School, University of Sydney, Sydney, NSW, Australia
• Frailty Syndrome: Assessment, Correlates, and Approach. 
  Division of Aging Grand Rounds, Nepean Clinical School, University of Sydney, Penrith, NSW
• Putting it all together: Approach to osteoporosis treatment. 
  American Geriatrics Society Annual Meeting, Seattle, WA
• Primary Care Challenges in Osteoporosis: A Geriatric Perspective. 
  American Geriatrics Society Annual Meeting, Seattle, WA
• Once a Year? New Approaches to Osteoporosis Treatment. 
  University of Miami Miller School of Medicine, Coral Gables, FL
• Biology of Aging. 
  Center on Aging, University of Connecticut Health Center, Farmington, CT
• Age-Related Bone Loss: Pathogenesis and Treatment (Osteoporosis 2006 - Update on Treatment), 2002. 
  Division of Geriatric Medicine, McGill University, Montreal, Canada
• Boning up on Cathepsin K. 
  The Centre for Bone and Periodontal Research, McGill University, Montreal, Canada
• Osteoclast Differentiation and the Regulation of Cathepsin K Expression. 
  University of Arkansas Medical Sciences, Little Rock, AK
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Other

• Some new food for thought: The role of vitamin D in the mental health of older adults. 
  Cherniack, E.P., Troen, B.R., Florez, H., Roos, B.A., and Levis, S
• Vitamin D Supplementation In Older Persons: Benefits And Requirements. 
  Levis, S., Cherniack, E.P., Florez, H., Roos, B.A., Troen, B.R, Future Medicine-Aging Health
• Identification of NFAT Binding Sites that Mediate RANKL Stimulation of Cathepsin K Promoter Activity. 
  Balkan, W., Martinez, A.F., Fernandez, I., Rodriguez,, M.A., Pang, M. and Troen, B.R
• Hypovitaminosis D: a stealthy epidemic requiring treatment. 
  Cherniack, E.P., Levis, S. and Troen, B.R
• Functional grouping of osteoclast genes revealed through microarray analysis. 
  Yang, G., Zaidi, M., Zhang, W., Zhu, L.L., Li, J., Iqbal, J., Varbanov, A., Gross, G., Phipps, R., Troen, B.R., Sun, L, Biochem Biophys Res Commun
• AP-1 Stimulates the Cathepsin K Promoter in RAW 264.7 Cells. 
  Pang, M., Martinez, A.F., Fernandez, I., Balkan, W., Troen, B.R
• Unlocking the Mysteries of Adult Stem Cells and Regenerative Medicine. 
  Howard, G.A., Schiller, P.C., D'Ippolito, G., Cheung, H.S., Troen, B.R., Roos, B.A
• RANK ligand and interferon gamma differentially regulate cathepsin gene expression in pre-osteoclastic cells. 
  Pang, M., Martinez, A.F., Jacobs, J., Balkan, W., Troen, B.R
• RANK-L induces the expression of NFATc1, but not of NFκB subunits during osteoclast formation. 
  Zhu, L., Zaidi, S., Moonga, B.S., Troen, B.R., Sun, Li
• Geripause: A Newly Defined Postmenopausal Phase. 
  Eskin, B.A. and Troen, B.R
• Macrophage Colony-Stimulating Factor Suppresses Osteoblast Formation. 
  Gyda, M., Corisdeo, S., Zaidi, M., and Troen, B.R
• New Insights into the Regulation of Cathepsin K Gene Expression by Osteoprotegerin Ligand. 
  Corisdeo, S., Gyda, M., Zaidi, M., Moonga, B.S., and Troen, B.R
• Transcription of Human Cathepsin B Is Mediated by Sp1 and Ets Family Factors in Glioma. 
  Yan, S., Berquin, I.M., Troen, B.R., Sloane, B.F
• Comparative responsiveness of HL60, HL60R and HL60R+ (LRARSN) cells to various differentiating agents. 
  Atkins, K.B., Troen, B.R
• Downstream sequences mediate induction of the mouse cathepsin L promoter by phorbol esters. 
  Troen, B.R., Chauhan, S.S., Ray, D., Gottesman, M.M, Cell Growth and Differ
• Use of a cloned multidrug resistance gene for co-amplification and overproduction of major excreted protein, a transformation-regulated secreted acid protease. 
  Kane, S.E., Troen, B.R., Gal, S., Ueda, K., Pastan, I.,Gottesman, M.M
• Effects of age and sex on certain metabolic functions and mitogenic activity in rat thymocytes. 
  Segal, J., Troen, B.R., Ingbar, S.H
• Sympathetic nervous system and aging in man. 
  Rowe, J.W. and Troen, B.R, Endocrine Reviews
• Osteoclast Differentiation and the Regulation of Cathepsin K Expression. 
  Troen, B.R
• Dysfunctional Osteoblasts, Impaired Osteoblastogenesis, Reduced Bone Formation and Severe Osteoporosis in a Calcineurin Aα Null Mouse. 
  Sun, L., Adebanjo, O. A., Liu, X. H., Moonga, B. S., Inzerillo, A., Koval, A., Wu, X. B., Bevis, P. J. R., Blair, H. C., Conner, D., Seidman, J., Troen, B.R., Epstein...
• Retinoic acid induces cathepsin D gene expression in HL-60 cells. 
  Atkins, K.B., Troen, B.R
• Tyrosine kinase dependence of the TPA regulated IL-8 gene expression in U937 cells. 
  Atkins, K.B., Troen, B.R
• Are tumor promoter and transformation responsive elements distinct within the cathepsin L gene? 
  Troen, B.R., Chang, M.Y
• Analysis of the induction of mouse cathepsin L promoter by cAMP. 
  Chang, M.Y., Troen, B.R
• Isolation and characterization of the promoter for a transformation-regulated cathepsin. 
  Troen, B.R., Gottesman, M.M
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