C. SpencerYostMD

Anesthesiology • San Francisco, CA

Critical Care Medicine

Clinical Professor, Anesthesiology, UCSF School of Medicine

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Office
505 Parnassus Ave
San Francisco, CA 94143
Phone+1 415-476-1000

Fax+1 415-353-2765
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Education & Training

University of California San Francisco School of MedicinePost-Doctoral Fellowship, Molecular Neurobiology, 1987 - 1991
University of Pennsylvania Health SystemFellowship, Critical Care Medicine (Anesthesiology), 1986 - 1987
Los Angeles County-Harbor-UCLA Medical CenterResidency, Anesthesiology, 1984 - 1986
University of Southern California/LAC+USC Medical CenterInternship, Internal Medicine, 1983 - 1984
University of California San Francisco School of MedicineClass of 1983

Certifications & Licensure

CA State Medical License 1984 - 2025
PA State Medical License 1986 - 1988
American Board of Anesthesiology Anesthesiology
American Board of Anesthesiology Critical Care Medicine

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Publications & Presentations

PubMed

82 citations
Successful implementation of an Enhanced Recovery After Surgery program shortens length of stay and improves postoperative pain, and bowel and bladder function after c...
Ankit Sarin, Erik S. Litonius, Ramana K. Naidu, C. Spencer Yost, Madhulika G. Varma, Lee-lynn Chen> ;BMC Anesthesiology. 2015 Jan 1
34 citations
Discrete change in volatile anesthetic sensitivity in mice with inactivated tandem pore potassium ion channel TRESK.
Yun Jeong Chae, Jianan Zhang, Paul Au, Marta Sabbadini, Guo-xi Xie, C. Spencer Yost> ;Anesthesiology. 2010 Dec 1
6 citations
Anaphylaxis complicating graft reperfusion during orthotopic liver transplantation: a case report.
A. Anderson, Helge Eilers, C. Spencer Yost> ;Transplantation Proceedings. 2010 Jun 1
41 citations
Regional expression of the anesthetic-activated potassium channel TRESK in the rat nervous system
SieHyeon Yoo, Jia Liu, Marta Sabbadini, Paul Au, Guo-xi Xie, C. Spencer Yost> ;Neuroscience Letters. 2009 Nov 6
19 citations
Molecular Biology of Background K Channels: Insights from K2P Knockout Mice
Marta Sabbadini, C. Spencer Yost> ;Journal of Molecular Biology. 2009 Feb 6
17 citations
Knockout of the gene encoding the K2P channel KCNK7 does not alter volatile anesthetic sensitivity
C. Spencer Yost, Irene Oh, Edmond I. Eger, James M. Sonner> ;Behavioural Brain Research. 2008 Nov 21
3 citations
The curse of the drinking class.
C. Spencer Yost, Michael A. Gropper> ;Critical Care Medicine. 2008 Jun 1
76 citations
A new look at the respiratory stimulant doxapram.
C. Spencer Yost> ;CNS Drug Reviews. 2006 Sep 1
20 citations
Chirality in anesthesia II: stereoselective modulation of ion channel function by secondary alcohol enantiomers.
Robert J Brosnan, Diane Gong, Joseph F. Cotten, Bharat Keshavaprasad, C. Spencer Yost, Edmond I. Eger, James M. Sonner> ;Anesthesia and Analgesia. 2006 Jul 1
58 citations
The ventilatory stimulant doxapram inhibits TASK tandem pore (K2P) potassium channel function but does not affect minimum alveolar anesthetic concentration.
Joseph F. Cotten, Bharat Keshavaprasad, Michael J. Laster, Edmond I. Eger, C. Spencer Yost> ;Anesthesia and Analgesia. 2006 Mar 1
39 citations
Species-specific differences in response to anesthetics and other modulators by the K2P channel TRESK.
Bharat Keshavaprasad, Canhui Liu, John D. Au, Christoph H. Kindler, Joseph F. Cotten, Yost Cs> ;Anesthesia and Analgesia. 2005 Oct 1
10 citations
Antiemetics of the 5-hydroxytryptamine 3A antagonist class inhibit muscle nicotinic acetylcholine receptors.
Matthias Paul, Robert Callahan, John D. Au, Christoph H. Kindler, C. Spencer Yost> ;Anesthesia and Analgesia. 2005 Sep 1
49 citations
Two-pore domain potassium channels : New sites of local anesthetic action and toxicity
Christoph H. Kindler, C. Spencer Yost> ;Regional Anesthesia and Pain Medicine. 2005 May 1
29 citations
Protective effects of TASK-3 (KCNK9) and related 2P K channels during cellular stress
Canhui Liu, Joseph F. Cotton, Jennifer A. Schuyler, Christian S. Fahlman, John D. Au, Philip E. Bickler, C. Spencer Yost> ;Brain Research. 2005 Jan 21
86 citations
Potent activation of the human tandem pore domain K channel TRESK with clinical concentrations of volatile anesthetics.
Canhui Liu, John D. Au, Hilary Liao Zou, Joseph F. Cotten, C. Spencer Yost> ;Anesthesia and Analgesia. 2004 Dec 1
15 citations
Identification of native rat cerebellar granule cell currents due to background K channel KCNK5 (TASK-2)
Joseph F. Cotten, Hilary Liao Zou, Canhui Liu, John D. Au, C. Spencer Yost> ;Brain Research. Molecular Brain Research. 2004 Sep 28
9 citations
Immunolocalization of TASK-3 (KCNK9) to a subset of cortical neurons in the rat CNS.
Robert Callahan, Dmitriy A Labunskiy, Anna Logvinova, Mona Abdallah, Canhui Liu, Joseph F. Cotten, C. Spencer Yost> ;Biochemical and Biophysical Research Communications. 2004 Jun 25
6 citations
Intraoperative Fluid Management of Living Donor Versus Cadaveric Liver Transplant Recipients
Claus U. Niemann, R. Hirose, Peter G. Stock, John P. Roberts, Susan Mandell, C. Spencer Yost> ;Transplantation Proceedings. 2004 Jun 1
70 citations
Functional inhibition by methadone of N-methyl-D-aspartate receptors expressed in Xenopus oocytes: stereospecific and subunit effects.
Robert Callahan, John D. Au, Matthias Paul, Canhui Liu, C. Spencer Yost> ;Anesthesia and Analgesia. 2004 Mar 1
9 citations
Genomic structure, cochlear expression, and mutation screening of KCNK6, a candidate gene for DFNA4
Anand N. Mhatre, Jiang Li, Arthur F. Chen, C. Spencer Yost, Richard J.H. Smith, Christoph H. Kindler, Anil K. Lalwani> ;Journal of Neuroscience Research. 2004 Jan 1
56 citations
Amide Local Anesthetics Potently Inhibit the Human Tandem Pore Domain Background K+ Channel TASK-2 (KCNK5)
Christoph H. Kindler, Matthias Paul, Hilary Liao Zou, Canhui Liu, Bruce D. Winegar, Andrew T. Gray, C. Spencer Yost> ;The Journal of Pharmacology and Experimental Therapeutics. 2003 Jul 1
32 citations
Update on tandem pore (2P) domain K+ channels.
Yost Cs> ;Current Drug Targets. 2003 May 1
27 citations
Intraoperative hemodynamics and liver function in adult-to-adult living liver donors.
Claus U. Niemann, John P. Roberts, Nancy L. Ascher, C. Spencer Yost> ;Liver Transplantation. 2002 Dec 1
41 citations
Characterization of the Interactions Between Volatile Anesthetics and Neuromuscular Blockers at the Muscle Nicotinic Acetylcholine Receptor
Matthias Paul, Ralf M Fokt, Christoph H. Kindler, Natalie C. J. Dipp, C. Spencer Yost> ;Anesthesia and Analgesia. 2002 Aug 1
17 citations
Evaluation of the splanchnic circulation with indocyanine green pharmacokinetics in liver transplant patients.
Claus U. Niemann, C. Spencer Yost, Susan Mandell, Thomas K. Henthorn> ;Liver Transplantation. 2002 May 1
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Hospital Affiliations

UCSF Medical CenterSan Francisco, California