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Carl June, MD, Oncology, Philadelphia, PA, Hospital of the University of Pennsylvania

CarlJuneMD

Oncology Philadelphia, PA

Professor, Pathology & Laboratory Medicine, Perelman School of Medicine

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Education & Training

  • University of Washington
    University of WashingtonFellowship, Hematology and Medical Oncology, 1983 - 1985
  • National Capital Consortium
    National Capital ConsortiumResidency, Internal Medicine, 1979 - 1983
  • Baylor College of Medicine
    Baylor College of MedicineClass of 1979

Certifications & Licensure

  • PA State Medical License
    PA State Medical License 2000 - 2024
  • MD State Medical License
    MD State Medical License 1997 - 2000
  • TX State Medical License
    TX State Medical License 1979 - 1997
  • WA State Medical License
    WA State Medical License 1983 - 1984
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

  • Elected Member The American Society for Clinical Investigation, 1992

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Expanding the Therapeutic Window for CAR T Cell Therapy in Solid Tumors: The Knowns and Unknowns of CAR T Cell Biology  
    Carl June, MD, Frontiers in Neurology
  • Induction of Resistance to Chimeric Antigen Receptor T Cell Therapy by Transduction of a Single Leukemic B Cell  
    Vijay G Bhoj, David M Barrett, Carl H June, Stephan A Grupp, David E Ambrose, Saar I Gill, Marco Ruella, Bruce L Levine, Shannon L Maude, Nature
  • Immunotherapy for Glioblastoma: Adoptive T-cell Strategies  
    Marcela V Maus, Carl H June, Clinical Cancer Research
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Abstracts/Posters

  • A Failure to Start: Aborted Activation of CAR T Cells in Chronic Lymphocytic Leukemia
    Carl H June, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
  • Single Chain Variable Fragment Linker Length Regulates CAR Biology and T Cell Efficacy
    Carl H June, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
  • Identification and Validation of Predictive Biomarkers to CD19- and BCMA-Specific CAR T-Cell Responses in CAR T-Cell Precursors
    Carl H June, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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Lectures

  • Chronic Lymphocytic Leukemia Cells Impair Mitochondrial Fitness in CD8+ T Cells and Impede CAR T Cell Efficacy 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Predictors of T Cell Expansion and Clinical Responses Following B-Cell Maturation Antigen-Specific Chimeric Antigen Receptor T Cell Therapy (CART-BCMA) for Relapsed/Re... 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
  • Clinical Predictors of T Cell Fitness for CAR T Cell Manufacturing and Efficacy in Multiple Myeloma 
    2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
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Press Mentions

  • Promising Treatment for Rare Cancer in Children Gives Hope to Experts
    Promising Treatment for Rare Cancer in Children Gives Hope to ExpertsApril 6th, 2023
  • Novel Treatment Shows Promise Against Rare Cancer in Kids
    Novel Treatment Shows Promise Against Rare Cancer in KidsApril 6th, 2023
  • Novel Treatment Shows Promise Against Rare Cancer in Kids
    Novel Treatment Shows Promise Against Rare Cancer in KidsApril 6th, 2023
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Hospital Affiliations