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Office
3400 Spruce St
15 Penn Tower
Philadelphia, PA 19104Phone+1 215-662-3914- Is this information wrong?
Education & Training
- University of WashingtonFellowship, Hematology and Medical Oncology, 1983 - 1985
- National Capital ConsortiumResidency, Internal Medicine, 1979 - 1983
- Baylor College of MedicineClass of 1979
Certifications & Licensure
- PA State Medical License 2000 - 2024
- MD State Medical License 1997 - 2000
- TX State Medical License 1979 - 1997
- WA State Medical License 1983 - 1984
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 1992
Clinical Trials
- Phase I/II Clinical Trial Combining hTERT Tumor Vaccine & Autologous T Cells in Patients With Advanced Myeloma Start of enrollment: 2006 Dec 01
Publications & Presentations
PubMed
- Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy.Metzloff, A., Padilla, M., Gong, N., Billingsley, M., Han, X., Merolle, M., Mai, D., Figueroa-Espada, C., Thatte, A., Haley, R., Mukalel, A., Hamilton, A., Alameh, M.,...> ;Advanced Materials. 2024 Feb 28
- Adoptive cellular therapy after hematopoietic stem cell transplantation.Vittayawacharin, P., Chu, Y., Bollard, C., Kongtim, P., June, C., Ciurea, S.> ;American Journal of Hematology. 2024 Jan 25
- 13 citationsMitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells.Connor A Tsuchida, Nadav Brandes, Raymund Bueno, Marena Trinidad, Thomas Mazumder, Bingfei Yu, Byungjin Hwang, Christopher Chang, Jamin Liu, Yang Sun, Caitlin R Hopkin...> ;Cell. 2023 Oct 12
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Journal Articles
- Expanding the Therapeutic Window for CAR T Cell Therapy in Solid Tumors: The Knowns and Unknowns of CAR T Cell BiologyCarl June, MD, Frontiers in Neurology
- Induction of Resistance to Chimeric Antigen Receptor T Cell Therapy by Transduction of a Single Leukemic B CellVijay G Bhoj, David M Barrett, Carl H June, Stephan A Grupp, David E Ambrose, Saar I Gill, Marco Ruella, Bruce L Levine, Shannon L Maude, Nature
- Immunotherapy for Glioblastoma: Adoptive T-cell StrategiesMarcela V Maus, Carl H June, Clinical Cancer Research
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Abstracts/Posters
- A Failure to Start: Aborted Activation of CAR T Cells in Chronic Lymphocytic LeukemiaCarl H June, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Single Chain Variable Fragment Linker Length Regulates CAR Biology and T Cell EfficacyCarl H June, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- Identification and Validation of Predictive Biomarkers to CD19- and BCMA-Specific CAR T-Cell Responses in CAR T-Cell PrecursorsCarl H June, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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Lectures
- Chronic Lymphocytic Leukemia Cells Impair Mitochondrial Fitness in CD8+ T Cells and Impede CAR T Cell Efficacy2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Predictors of T Cell Expansion and Clinical Responses Following B-Cell Maturation Antigen-Specific Chimeric Antigen Receptor T Cell Therapy (CART-BCMA) for Relapsed/Re...2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Clinical Predictors of T Cell Fitness for CAR T Cell Manufacturing and Efficacy in Multiple Myeloma2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
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Press Mentions
- Promising Treatment for Rare Cancer in Children Gives Hope to ExpertsApril 6th, 2023
- Novel Treatment Shows Promise Against Rare Cancer in KidsApril 6th, 2023
- Novel Treatment Shows Promise Against Rare Cancer in KidsApril 6th, 2023
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Hospital Affiliations
- Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania
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