
Susan M Domchek MD
Breast Cancer, Cancer Genetics/Cancer Risk Assessment, Hematologic Oncology
Basser Professor of Medicine, University Pennsylvania
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3400 Spruce St# 15Philadelphia, PA 19104
Phone+1 215-662-3914
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Education & Training
Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1998 - 2001
Mass General Brigham/Massachusetts General HospitalResidency, Internal Medicine, 1995 - 1998
Harvard Medical SchoolClass of 1995
Certifications & Licensure
NJ State Medical License 2022 - 2027
NY State Medical License 2024 - 2026
PA State Medical License 2001 - 2026
NC State Medical License 2020 - 2022
American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2012, 2014-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2012, 2014-2017
Clinical Trials
- Vaccine Plus Montanide ISA-51 and Sargramostim in Treating Patients With Stage IV Breast Cancer Start of enrollment: 2004 Feb 01
- Tamoxifen-MRI Study Start of enrollment: 2000 Sep 01
- Single Nucleotide Polymorphism (SNP) Panels and Risk Assessment in Women Undergoing Mammography Start of enrollment: 2010 Feb 01
Publications & Presentations
PubMed
- Sexual Function, Activity and Distress 24 Months After Surgical Menopause: What Happens After Menopause (WHAM)-A Prospective Controlled Study.Martha Hickey, Trevor Tejada-Berges, Susan M Domchek, Efrosinia O Krejany, Alison Brand
BJOG. 2026-05-01 - A randomized study of digital versus genetic counselor return of actionable genetic research results to biobank participants (RESPECT3 study).Anuja Rajendra Godbole, Elisabeth Wood, Brian Egleston, Lily Hoffman-Andrews, Sarah Brown
BMC Medical Ethics. 2026-03-31 - TBCRC 048 (Olaparib Expanded) Expansion Cohorts: Phase II Study of Olaparib Monotherapy for Patients With Metastatic Breast Cancer With Germline Mutations inor Somatic...Nadine M Tung, Mark E Robson, Tianyu Li, Rita Nanda, Payal D Shah
Journal of Clinical Oncology. 2026-03-10
Journal Articles
- Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization StudySusan M Domchek, Wendy K Chung, Patricia A Ganz, Robert L Nussbaum, Journal of the National Cancer Institute
- A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer RiskPatricia A Ganz, Amanda E Toland, Susan M Domchek, Tanja Pejovic, Clinical Cancer Research
- Ethical Implications of Direct-to-Consumer Hereditary Cancer TestsSusan Domchek, MD, JAMA
Press Mentions
T-cell Response to mRNA Vaccine Improved with Cytokine AdjuvantJune 9th, 2025
Four Penn Cancer Researchers Inducted as Fellows of the AACR AcademyMarch 10th, 2025
Clinical Trials Are Testing Ways to Prevent Breast CancerJanuary 15th, 2025
Grant Support
- University Of Pennsylvania Cancer Genetics NetworkNational Cancer Institute2002–2006
Professional Memberships
- Member
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