
Carl J Pepine MD
Preventive Cardiology, Clinical Pharmacology
Professor of Medicine, University Fla College of Medicine
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1329 SW Archer RoadSuite 5130, Room 5231Gainesville, FL 32610
Phone+1 352-273-9082
Fax+1 352-392-3606
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Summary
- Carl Pepine, MD, is a Cardiology specialist with a subspecialty in Preventive Cardiology based in Gainesville, FL. He attended Rutgers New Jersey Medical School and completed his residency and internship at various prestigious institutions, including Sidney Kimmel Medical College and Naval Regional Medical Center. Currently a professor at UF Health, Dr. Pepine is notable for his published research in cardiovascular health, specifically concerning women's heart health, as well as his role as Principal Investigator in numerous clinical trials. His accolades include multiple Castle Connolly awards, such as "America's Top Doctors," and the CMS Meaningful Use Stage 1 Certification.
Education & Training
Naval Regional Medical CenterResidency, Internal Medicine, 1968 - 1971
Sidney Kimmel Medical College at Thomas Jefferson University/TJUHResidency, Internal Medicine, 1967 - 1968
Allegheny Health Network Medical Education Consortium (AGH)Internship, Internal Medicine, 1966 - 1967
Rutgers New Jersey Medical SchoolClass of 1966
Certifications & Licensure
FL State Medical License 1974 - 2028
PA State Medical License 1967 - 1984
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014, 2016-2017
Clinical Trials
Publications & Presentations
PubMed
- Left ventricular end-diastolic pressure in women with ischemia and no obstructive coronary artery disease: The women's ischemia syndrome evaluation - Coronary microvas...Sachini Ranasinghe, Benita Tjoe, Joseph Chang, Galen Cook-Wiens, R David Anderson
International Journal of Cardiology. 2026-10-15 - Novel Home-Based Remotely Supervised High Intensity Interval Training is Safe and Feasible and Improves Aerobic Fitness and Adiposity in Older Adults.Stephanie Lapierre-Nguyen, Jin-Su Kim, Chatchamarn Soonhuae, Yasemin Sakarya, Eléonor Riesco
Medicine and Science in Sports and Exercise. 2026-08-06 - A meta-analysis of the long-term effects of antihypertensive therapy on the risk of major cardiovascular disease across 51 randomized trials.Qianqian Yang, Zeinab Bidel, Dexter Canoy, Guyu Zeng, William C Cushman
Nature Medicine. 2026-08-01
Journal Articles
- Gut Microbiota and Serum Metabolite Differences in African Americans and White Americans with High Blood Pressure☆Carl Pepine, MD, International Journal of Cardiology
Authored Content
- Invasive Functional Assessment in Patients with Angina and Coronary Microvascular Dysfunction A Plea for MoreMay 2020
- Invasive Functional Assessment in Patients with Angina and Coronary Microvascular Dysfunction A Plea for MoreMay 2020
- Hypertension Across a Woman’s Life CycleApril 2018
Press Mentions
BioCardia Releases Primary Endpoint Results of Open Label Roll-in Cohort of CardiAMP Cell Therapy in Chronic Myocardial Ischemia TrialSeptember 19th, 2025
CardiAMP-HF Trial Data Presented for BioCardia Cardiac Cell Therapy for HFrEFApril 7th, 2025
HMN 2025: How Women with Chest Ache Could Not Want Intensive Medical RemedyApril 1st, 2025
Grant Support
- Antihypertensive Mechanisms of Minocycline in Resistant Hypertension: Role of the gut microbiota-brain-immune axisUNIVERSITY OF FLORIDA2023–2029
- Ufrcc For Cardiovascular Cell Therapy Research NetworkNational Heart, Lung, And Blood Institute2012
- Women'S Ischemia Syndrome Evaluation (WISE) Coronary Vascular DysfunctionNational Heart, Lung, And Blood Institute2008–2011
- Ancillary Functional Studies For The CctrnNational Heart, Lung, And Blood Institute2008–2011
- Ufcc For Cardiovascular Cell Therapy Research NetworkNational Heart, Lung, And Blood Institute2007–2011
Professional Memberships
- Member
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