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Cheng-Chia Wu, MD, Radiation Oncology, New York, NY, New York-Presbyterian/Hudson Valley Hospital

Cheng-ChiaWuMD

Radiation Oncology • New York, NY

Central Nervous System Cancer, Pediatric Radiation Oncology, Sarcoma

Assistant Professor Tenure Track

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Overview of Dr. Wu

#TheFussAboutFUS

I am a physician scientist with dual M.D./Ph.D. degrees and is currently a second year Tenure-Track Assistant Professor at the Department of Radiation Oncology, at Columbia University Irving Medical Center. My clinical focus is on pediatric radiation oncology. I am interested is in pediatric and central nervous system (CNS) malignancies. My area of expertise is in radiation biology, cancer research, and tumor vasculature. I completed my MD/PhD training studying the role of 20-HETE in the microvasculature and how it contributes to hypertension in preclinical murine models. This was supported by the NIH-F30 funding mechanism. From there, it led to my interests in tumor vascular biology and radiation oncology. I am currently focused on pediatric CNS malignancy research with an emphasis on diffuse midline glioma/diffuse intrinsic pontine glioma and glioblastoma. Working in a multidisciplinary fashion with pediatric neuro-oncology, surgery, pathology, clinical trial team and bioengineering, we are interested in translating novel techniques for drug delivery across the blood brain barrier to improve outcomes. My lab is specifically studying the use of non-invasive focused ultrasound (FUS)-mediated blood brain barrier-opening in combination with radiation, novel drug delivery, and immunotherapy. My research goals are to establish the use of new technology and bridge the gap between the laboratory and the clinic, and vice versa. My hope is that these projects will lay the groundwork for novel treatment strategies in kids.

Education & Training

  • New York Presbyterian Hospital (Columbia Campus)
    New York Presbyterian Hospital (Columbia Campus)Residency, Radiation Oncology, 2014 - 2018
  • Greenwich Hospital Association
    Greenwich Hospital AssociationInternship, Internal Medicine, 2013 - 2014
  • New York Medical College
    New York Medical CollegeClass of 2013, MD, PhD

Certifications & Licensure

  • FL State Medical License
    FL State Medical License 2020 - Present
  • NY State Medical License
    NY State Medical License Active through 2025
  • NJ State Medical License
    NJ State Medical License 2023 - 2025
  • CT State Medical License
    CT State Medical License 2023 - 2024
  • American Board of Radiology Radiation Oncology

Awards, Honors, & Recognition

  • RSNA Roentgen Resident/Fellow Research Award Radiological Society of North America, 2018
  • Travel Award Winter Eicosanoid Conference, 2009-2012
  • Travel Award Keystone Symposia - Bioactive Lipids, 2010
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Clinical Trials

Publications & Presentations

PubMed

Press Mentions

  • An Ultrasound Device May Unlock Brain Cancer Treatment, Early Study Shows
    An Ultrasound Device May Unlock Brain Cancer Treatment, Early Study ShowsMay 12th, 2023
  • Ultrasound Allows a Chemotherapy Drug to Enter the Human Brain
    Ultrasound Allows a Chemotherapy Drug to Enter the Human BrainMay 2nd, 2023
  • Ultrasound Allows a Chemotherapy Drug to Enter the Human Brain
    Ultrasound Allows a Chemotherapy Drug to Enter the Human BrainMay 2nd, 2023
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Grant Support

  • Focused Ultrasound Consortium for Treatment of Children Diagnosed with Diffuse Midline GliomasSebastian Strong Foundation2023–2024
  • Sebastian Strong FoundationSebastian Strong Foundation2022–2023
  • Focused Ultrasound Delivery of Panobinostat and Radiation for DIPG/DMGSt. Baldrick's Foundation (Hannah's Heroes)2021–2022
  • Focused Ultrasound and Drug Delivery for Diffuse Intrinsic Pontine Glioma/Diffuse Midline GliomaGary and Yael Fegel Family Foundation2020–2022
  • RNA Sequencing for Immune Profile for Focused Ultrasound-Mediated BBB-Opening for GlioblastomaGary and Yael Fegel Family Foundation2020–2021
  • A Deep Learning Substitute for Gadolinium Contrast Detects Focused Ultrasound-Induced Blood Brain Barrier Opening in MiceZuckerman Institute, Columiba2020–2021
  • Focused Ultrasound Enhanced Antibody Delivery and Immunogenicity in GlioblastomaMatheson Foundation2019–2020
  • Focused Ultrasound-Induced Blood Brain Barrier Disruption in Checkpoint Blockade ImmunotherapyIrving Institute for Clinical and Translationsl Research, Imaging Pilot Award2016–2017
  • Focused Ultrasound-Induced Blood Brain Barrier Disruption in Checkpoint Blockade Immunotherapy and the Abscopal EffectAmerican Society for Radiation Oncology, Resident Seed Grant2016–2017
  • Phase I feasibility trial for the role of cannabis in patients with glioblastoma treated with radiation and temozolomideIrving Institute for Clinical and Translationsl Research, CTO Pilot Grant2015–2016
  • 20-HETE regulation of androgen-induced hypertensionNIH - Ruth L. Kirschstein National Research Service Award (F30)2009–2014
  • 20-HETE in prostate cancer growth and metastasisAmerican Medical Association - Seed Grant2011–2012

Committees

  • Member, Children Oncology Group - Rare Tumor Committee 2020 - Present
  • Member, Trans-Departmental Children's Health Council - Columbia 2020 - Present

Professional Memberships

Other Languages

  • Chinese (Mandarin), Taiwanese

Hospital Affiliations

External Links

  • My Bibliographyhttps://www.ncbi.nlm.nih.gov/sites/myncbi/cheng-chia.wu.1/bibliography/43862917/public/?sort=date&direction=ascending
  • Laboratory Websitehttps://www.vagelos.columbia.edu/about-us/explore-vp-s/departments-centers/department-radiation-oncology/research/research-labs/initiative-drug-delivery-innovation-laboratory

Dr. Cheng-Chia Wu, Dr. Cheng-Chia Wu, MD, Dr. C Wu