ChrisannKyiMD

PubMed

• A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results.
  Amy R Rappaport, Chrisann Kyi, Monica Lane, Meghan G Hart, Melissa L Johnson, Brian S Henick, Chih-Yi Liao, Amit Mahipal, Ardaman Shergill, Alexander I Spira, Jonathan...> ;Nature Medicine. 2024 Mar 27
• A phase 2 trial of zanidatamab in HER2-overexpressed advanced endometrial carcinoma and carcinosarcoma (ZW25-IST-2).
  Melissa Lumish, M Herman Chui, Qin Zhou, Alexia Iasonos, Debra Sarasohn, Seth Cohen, Claire Friedman, Rachel Grisham, Jason Konner, Chrisann Kyi, Maria Rubinstein, Tif...> ;Gynecologic Oncology. 2024 Mar 1
• 1 citations
  A phase 2, multicenter, open-label study of anti-LAG-3 ieramilimab in combination with anti-PD-1 spartalizumab in patients with advanced solid malignancies.
  Lin, C., Garralda, E., Schöffski, P., Hong, D., Siu, L., Martin, M., Maur, M., Hui, R., Soo, R., Chiu, J., Zhang, T., Ma, B., Kyi, C., Tan, D., Cassier, P., Sarantopou...> ;Oncoimmunology. 2024 Jan 1
• Assessing the Genomic Landscape of Cervical Cancers: Clinical Opportunities and Therapeutic Targets.
  Claire F Friedman, Vignesh Ravichandran, Kathryn Miller, Chad Vanderbilt, Qin Zhou, Alexia Iasonos, Malavika Vivek, Pamela Mishra, Mario M Leitao Jr, Vance Broach, Yuk...> ;Clinical Cancer Research. 2023 Nov 14
• 1 citations
  Dual targeting ovarian cancer by Muc16 CAR T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1.
  Sung Soo Mun, Jeremy Meyerberg, Leila Peraro, Tatyana Korontsvit, Thomas Gardner, Manish Malviya, Chrisann Kyi, Roisin E O'Cearbhaill, Cheng Liu, Tao Dao, David A Sche...> ;Cancer Immunology, Immunotherapy. 2023 Nov 1
• Dual targeting ovarian cancer by Muc16 CAR-T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1.
  Sung Soo Mun, Leila Peraro, Jeremy Meyerberg, Tatyana Korontsvit, Manish Malviya, Thomas Gardner, Chrisann Kyi, Roisin E O'Cearbhaill, Cheng Liu, Tao Dao, David A Sche...> ;Research Square. 2023 May 8
• 4 citations
  Durvalumab with or without tremelimumab in patients with persistent or recurrent endometrial cancer or endometrial carcinosarcoma: A randomized open-label phase 2 study.
  Maria M Rubinstein, Eric Rios Doria, Jason Konner, Stuart Lichtman, Qin Zhou, Alexia Iasonos, Debra Sarasohn, Tiffany Troso-Sandoval, Claire Friedman, Roisin O'Cearbha...> ;Gynecologic Oncology. 2023 Feb 1
• 7 citations
  Gastric-type adenocarcinoma of the cervix: Clinical outcomes and genomic drivers.
  Sarah Ehmann, Dib Sassine, Alli M Straubhar, Aaron M Praiss, Carol Aghajanian, Kaled M Alektiar, Vance Broach, Karen A Cadoo, Elizabeth L Jewell, Amir Momeni Boroujeni...> ;Gynecologic Oncology. 2022 Dec 1
• 63 citations
  Phase I/II study of the LAG-3 inhibitor ieramilimab (LAG525) ± anti-PD-1 spartalizumab (PDR001) in patients with advanced malignancies.
  Patrick Schöffski, Daniel S W Tan, Miguel Martín, María Ochoa-de-Olza, John Sarantopoulos, Richard D Carvajal, Chrisann Kyi, Taito Esaki, Amy Prawira, Wallace Akerley,...> ;Journal for Immunotherapy of Cancer. 2022 Feb 1
• 12 citations
  Uterine mesenchymal tumors harboring ALK fusions and response to ALK-targeted therapy.
  Chrisann Kyi, Claire F. Friedman, Jennifer J. Mueller, Ryma Benayed, Marc Ladanyi, Maria E. Arcila, Soo-Ryum Yang, Martee L. Hensley, Sarah Chiang> ;Gynecologic Oncology Reports. 2021 Aug 1
• 3 citations
  Phase I dose escalation safety and feasibility study of autologous WT1-sensitized T cells for the treatment of patients with recurrent ovarian cancer.
  Chrisann Kyi, Ekaterina Doubrovina, Qin Zhou, Sara Kravetz, Alexia Iasonos, Carol Aghajanian, Paul Sabbatini, David R. Spriggs, Richard J. O'Reilly, Roisin E. O'Cearbh...> ;Journal for Immunotherapy of Cancer. 2021 Aug 1
• 4 citations
  Pattern of disease and response to pembrolizumab in recurrent cervical cancer.
  Kathryn Miller, Olga T. Filippova, Sara A. Hayes, Nadeem R. Abu-Rustum, Carol Aghajanian, Vance Broach, Lora H. Ellenson, Pier Selenica, Elizabeth L. Jewell, Chrisann ...> ;Gynecologic Oncology Reports. 2021 Jul 10
• 75 citations
  Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial
  Robert L. Ferris, William C. Spanos, Rom Leidner, Anthony Gonçalves, Uwe M Martens, Chrisann Kyi, William H. Sharfman, Christine H. Chung, Lot A. Devriese, Hélène Gaut...> ;Journal for Immunotherapy of Cancer. 2021 Jun 1
• 6 citations
  A phase I open-label study of selinexor with paclitaxel and carboplatin in patients with advanced ovarian or endometrial cancers.
  Maria M. Rubinstein, Rachel N. Grisham, Karen Cadoo, Chrisann Kyi, William P. Tew, Claire F. Friedman, Roisin E. O'Cearbhaill, Dmitriy Zamarin, Qin Zhou, Alexia Iasono...> ;Gynecologic Oncology. 2021 Jan 1
• 5 citations
  Impact of tumor heterogeneity and microenvironment in identifying neoantigens in a patient with ovarian cancer
  Tao Dao, Martin G. Klatt, Tatyana Korontsvit, Sung Soo Mun, Sean Guzman, Marissa Mattar, Oliver Zivanovic, Chrisann Kyi, Nicholas D. Socci, Roisin E. O'Cearbhaill, Dav...> ;Cancer Immunology, Immunotherapy. 2021 May 1
• 81 citations
  Therapeutic Immune Modulation Against Solid Cancers with Intratumoral Poly-ICLC: A Pilot Trial
  Chrisann Kyi, Vladimir Roudko, Rachel Lubong Sabado, Yvonne M. Saenger, William Loging, John Mandeli, Tin Htwe Thin, Deborah Lehrer, Michael J. Donovan, Marshall R. Po...> ;Clinical Cancer Research. 2018 Jan 1
• 26 citations
  Whole-blood RNA transcript-based models can predict clinical response in two large independent clinical studies of patients with advanced melanoma treated with the che...
  Philip Friedlander, Karl Wassmann, Alan M. Christenfeld, David E. Fisher, Chrisann Kyi, John M. Kirkwood, Nina Bhardwaj, William Oh> ;Journal for Immunotherapy of Cancer. 2017 Aug 15
• 190 citations
  The Spectrum of Serious Infections Among Patients Receiving Immune Checkpoint Blockade for the Treatment of Melanoma.
  Maria Del Castillo, Fabian Andres Romero, Esther Arguello, Chrisann Kyi, Michael A. Postow, Gil Redelman-Sidi> ;Clinical Infectious Diseases. 2016 Dec 1
• 123 citations
  Immune checkpoint inhibitor combinations in solid tumors: opportunities and challenges
  Chrisann Kyi, Michael A. Postow> ;Immunotherapy. 2016 Jun 28
• 77 citations
  Ipilimumab in patients with melanoma and autoimmune disease
  Chrisann Kyi, Richard D. Carvajal, Michael A. Postow> ;Journal for Immunotherapy of Cancer. 2014 Oct 14
• 88 citations
  Opportunistic infections in patients treated with immunotherapy for cancer.
  Chrisann Kyi, Matthew D. Hellmann, Paul B. Chapman, Michael A. Postow> ;Journal for Immunotherapy of Cancer. 2014 Jun 18
• 182 citations
  Checkpoint blocking antibodies in cancer immunotherapy.
  Chrisann Kyi, Michael A. Postow> ;FEBS Letters. 2014 Jan 21
• 89 citations
  Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients.
  Shigehisa Kitano, Takemasa Tsuji, Caillian Liu, Daniel Hirschhorn-Cymerman, Chrisann Kyi, Zhenyu Mu, James P. Allison, Sacha Gnjatic, Jianda Yuan> ;Cancer Immunology Research. 2013 Oct 1
• 6 citations
  A case report of trastuzumab dose in gastric cancer.
  Chrisann Kyi, Manish A. Shah> ;Journal of Gastrointestinal Oncology. 2013 Sep 25
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