ChristophBuettnerMDPhD

PubMed

• Active Cushing Disease Is Characterized by Increased Adipose Tissue Macrophage Presence.
  Irene T Lee, Alexandria Atuahene, Hale Ergin Egritag, Ling Wang, Michael J. Donovan, Christoph Buettner, Eliza B. Geer> ;The Journal of Clinical Endocrinology and Metabolism. 2019 Jun 1
• Fat cells gobbling up norepinephrine
  Vitaly Ryu, Christoph Buettner> ;PLOS Biology. 2019 Feb 7
• iPSC-derived familial Alzheimer’s PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling
  Cesar L. Moreno, Lucio Della Guardia, Valeria Shnyder, Maitane Ortiz-Virumbrales, Ilya Kruglikov, Bin Zhang, Eric E. Schadt, Rudolph E. Tanzi, Scott Noggle, Christoph ...> ;Molecular Neurodegeneration. 2018 Jun 26
• 3 citations
  Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
  Steven E. Arnold, Zoe Arvanitakis, Shannon L. Macauley-Rambach, Aaron M. Koenig, Hoau Yan Wang, Rexford S. Ahima, Suzanne Craft, Sam Gandy, Christoph Buettner, Luke E....> ;Nature Reviews Neurology. 2018 Jan 29
• Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice.
  Carmen Argmann, Sara Violante, Tetyana Dodatko, Mariana P. Amaro, Jacob Hagen, Virginia L. Gillespie, Christoph Buettner, Eric E. Schadt, Sander M. Houten> ;Biochimica et Biophysica Acta. 2017 Dec 1
• 24 citations
  Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling.
  Fanny Langlet, Rebecca A. Haeusler, Daniel Lindén, Elke Ericson, Tyrrell Norris, Anders Johansson, Joshua R. Cook, Kumiko S. Aizawa, Ling Wang, Christoph Buettner, Dom...> ;Cell. 2017 Nov 2
• 24 citations
  Blocking FSH induces thermogenic adipose tissue and reduces body fat
  Peng Liu, Yaoting Ji, Tony Yuen, Elizabeth Rendina-Ruedy, Victoria E. DeMambro, Samarth Dhawan, Wahid Abu-Amer, Sudeh Izadmehr, Bin Zhou, Andrew C. Shin, Rauf Latif, P...> ;Nature. 2017 Jun 1
• Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis
  Katrin Fischer, Henry H. Ruiz, Kevin Jhun, Brian Finan, Douglas J. Oberlin, Verena van der Heide, Anastasia V. Kalinovich, Natasa Petrovic, Yochai Wolf, Christoffer Cl...> ;Nature Medicine. 2017 Apr 17
• Chronic Intranasal Insulin Does Not Affect Hepatic Lipids but Lowers Circulating BCAAs in Healthy Male Subjects.
  Thomas Scherer, Peter Wolf, Sabina Smajis, Melania Gaggini, Martina Theresa Hackl, Amalia Gastaldelli, Peter Klimek, Elisa Einwallner, Rodrig Marculescu, Anton Luger, ...> ;The Journal of Clinical Endocrinology and Metabolism. 2017 Apr 1
• 5 citations
  Insulin Receptor Signaling in Pomc, but Not Agrp, Neurons Controls Adipose Tissue Insulin Action
  Christoph Buettner, MD> ;Diabetes Care. 2017 Apr 8
• Embryonic ablation of neuronal VGF increases energy expenditure and reduces body weight.
  Jiang, C., Lin, W., Sadahiro, M., Shin, A. C., Buettner, C., Salton, S. R.> ;Neuropeptides. 2016 Dec 28
• Perinatal DDT Exposure Induces Hypertension and Cardiac Hypertrophy in Adult Mice.
  La Merrill, M. A., Sethi, S., Benard, L., Moshier, E., Haraldsson, B., Buettner, C.> ;Environmental health perspectives. 2016 Nov 2
• Proinflammatory cytokines remain elevated despite long-term remission in Cushing's disease: a prospective study.
  Shah, N., Ruiz, H. H., Zafar, U., Post, K. D., Buettner, C., Geer, E. B.> ;Clinical endocrinology. 2016 Sep 16
• Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders
  Soojeong Kang, Russell Dahl, Wilson Hsieh, Andrew C. Shin, Krisztina Zsebo, Christoph Buettner, Roger J. Hajjar, Djamel Lebeche> ;Journal of Biological Chemistry. 2016 Mar 4
• 4 citations
  Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCA...
  Ruiz, H. H., Chi, T., Shin, A. C., Lindtner, C., Hsieh, W., Ehrlich, M. E., Gandy, S., Buettner, C.> ;Alzheimer's & dementia : the journal of the Alzheimer's Association. 2016 Mar 2
• Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer’s APP/PSEN1 mice by gene targeting of diabetes/Alzheimer’s-related Sorcs1
  Elysse M. Knight, Henry H. Ruiz, Soong Ho Kim, Jessica C. Harte, Wilson Hsieh, Charles G. Glabe, William L. Klein, Alan D. Attie, Christoph Buettner, Michelle E. Ehrli...> ;Acta neuropathologica communications. 2016 Feb 25
• Insulin Regulates Hepatic Triglyceride Secretion and Lipid Content via Signaling in the Brain.
  Thomas Scherer, Claudia Lindtner, James O'Hare, Martina Theresa Hackl, Elizabeth Zielinski, Angelika Freudenthaler, Sabina Baumgartner-Parzer, Klaus Tödter, Joerg Heer...> ;Diabetes. 2016 Feb 8
• Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism
  Jae Hoon Jeong, Dong Kun Lee, Clemence Blouet, Henry H. Ruiz, Christoph Buettner, Streamson C. Chua, Gary J. Schwartz, Young Hwan Jo> ;Molecular metabolism. 2015 Jun 1
• Role of VGF-derived carboxy-terminal peptides in energy balance and reproduction: analysis of "humanized" knockin mice expressing full-length or truncated VGF.
  Masato Sadahiro, Connor Erickson, Wei Jye Lin, Andrew C. Shin, Maria Razzoli, Cheng Jiang, Samira Fargali, Allison Gurney, Kevin Kelley, Christoph Buettner, Alessandro...> ;Endocrinology. 2015 Feb 12
• Mitochondrial Shape Governs BAX-Induced Membrane Permeabilization and Apoptosis
  Thibaud T. Renault, Konstantinos V. Floros, Rana Elkholi, Kelly-Ann Corrigan, Yulia Kushnareva, Shira Y. Wieder, Claudia Lindtner, Madhavika N. Serasinghe, James J. As...> ;Molecular Cell. 2015 Jan 8
• 23 citations
  Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer
  Agnes Stachnik, Tony Yuen, Jameel Iqbal, Miriam Sgobba, Yogesh K. Gupta, Ping Lu, Graziana Colaianni, Yaoting Ji, Ling Ling Zhu, Se Min Kim, Jianhua Li, Peng Liu, Sude...> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Dec 16
• 3 citations
  Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism
  Andrew C. Shin, Martin Fasshauer, Nika Filatova, Linus A. Grundell, Elizabeth Zielinski, Jian Ying Zhou, Thomas Scherer, Claudia Lindtner, Phillip J. White, Amanda L. ...> ;Cell Metabolism. 2014 Nov 4
• Why leptin keeps you warm
  Young Hwan Jo, Christoph Buettner> ;Molecular metabolism. 2014 Nov 1
• 37 citations
  Perinatal Exposure of Mice to the Pesticide DDT Impairs Energy Expenditure and Metabolism in Adult Female Offspring
  Michele A. La Merrill, Emma Karey, Erin Moshier, Claudia Lindtner, Michael R. La Frano, John W. Newman, Christoph Buettner> ;PLOS ONE. 2014 Jul 30
• Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish.
  Howarth, D. L., Lindtner, C., Vacaru, A. M., Sachidanandam, R., Tsedensodnom, O., Vasilkova, T., Buettner, C., Sadler, K. C.> ;PLoS genetics. 2014 May 31
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Journal Articles

• iPSC-Derived Familial Alzheimer’s PSEN2 N141I Cholinergic Neurons Exhibit Mutation-Dependent Molecular Pathology Corrected by Insulin Signaling  
  Christoph Buettner, MD, BioMed Central