ChristopherVDeSimoneMDPhD

PubMed

• Regional Differences in the Outcomes of Catheter Ablation for Atrial Fibrillation in the United States.
  Siddharth Agarwal, Charu Debnath, Muhammad Bilal Munir, Christopher V DeSimone, Abhishek Deshmukh, Zain Ul Abideen Asad> ;Heart Rhythm. 2024 Apr 10
• 1 citations
  Infective Endocarditis Involving Implanted Cardiac Electronic Devices: JACC Focus Seminar 1/4.
  Supavit Chesdachai, Zerelda Esquer Garrigos, Christopher V DeSimone, Daniel C DeSimone, Larry M Baddour> ;Journal of the American College of Cardiology. 2024 Apr 9
• Electrical storm after left ventricular assist device (LVAD) implantation.
  Suganya Karikalan, Min Choon Tan, Nan Zhang, Hicham El-Masry, Ammar M Killu, Christopher V DeSimone, Abhishek J Deshmukh, Christopher J McLeod, Dan Sorajja, Komandoor ...> ;Journal of Cardiovascular Electrophysiology. 2024 Apr 9
• 1 citations
  Regional differences in the outcomes of catheter ablation for ventricular tachycardia in the United States.
  Gurukripa N Kowlgi, Siddharth Agarwal, Muhammad Bilal Munir, Abhishek Deshmukh, Christopher V DeSimone, Zain Ul Abideen Asad> ;Heart Rhythm. 2024 Mar 20
• Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry.
  Tolga Aksu, Roderick Tung, Tom De Potter, Timothy M Markman, Pasquale Santangeli, Jeanne du Fay de Lavallaz, Jeffrey R Winterfield, Tina Baykaner, Daniel Alyesh, Jacqu...> ;Journal of Interventional Cardiac Electrophysiology. 2024 Mar 18
• Outcomes of patients with hypertrophic cardiomyopathy undergoing percutaneous left atrial appendage occlusion.
  Agarwal, S., Munir, M., DeSimone, C., Deshmukh, A., Alkhouli, M., Asad, Z.> ;Journal of Interventional Cardiac Electrophysiology. 2024 Feb 27
• 1 citations
  Efficacy and safety of pulsed field ablation for atrial fibrillation: A systematic review and meta-analysis.
  Agarwal, S., Usama Qamar, Siddharth Agarwal, Satyam Krishan, Abhishek Deshmukh, Christopher V DeSimone, Stavros Stavrakis, Jonathan P Piccini, Zain Ul Abideen Asad> ;Pacing and Clinical Electrophysiology. 2024 Mar 1
• Risk factors, clinical implications, and management of peridevice leak following left atrial appendage closure: A systematic review.
  Helal, B., Khan, J., AlJayar, D., Khan, M., Alabdaljabar, M., Asad, Z., DeSimone, C., Deshmukh, A.> ;Journal of Interventional Cardiac Electrophysiology. 2024 Jan 6
• Outcomes and readmissions in patients with nonalcoholic fatty liver disease undergoing catheter ablation for atrial fibrillation.
  Siddharth Agarwal, Muhammad Bilal Munir, Charu Debnath, Christopher V DeSimone, Abhishek Deshmukh, Stavros Stavrakis, Nandan S Anavekar, Zain Ul Abideen Asad> ;Heart Rhythm. 2024 Apr 1
• Linear and spiral ablation catheters for ventricular pulsed field ablation.
  Tan, N., DeSimone, C.> ;Journal of Interventional Cardiac Electrophysiology. 2023 Dec 22
• Ventricular fibrillation and ventricular tachycardia post-SARS-CoV-2-targeted mRNA/viral vector vaccination.
  Agarwal, S., Mariam Shariff, Justin Lee, Siddarth Agarwal, Zain Asad, Daniel C DeSimone, Abhishek Deshmukh, Christopher V DeSimone, Ashish Kumar> ;Heart Rhythm O2. 2023 Dec 1
• The effect of weight loss on recurrence of atrial fibrillation after catheter ablation: A systematic review and meta-analysis.
  Khawaja Hassan Akhtar, Ali Haider Jafry, Christopher Beard, Yusra Minahil Nasir, Siddharth Agarwal, Jehanzeb Khan, Shari Clifton, Jessica Reece, Muhammad Bilal Munir, ...> ;Journal of Cardiovascular Electrophysiology. 2023 Dec 1
• Outcomes of Catheter Ablation for Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy.
  Siddharth Agarwal, Muhammad Bilal Munir, Harsh Patel, Christopher V DeSimone, Abhishek Deshmukh, Zain Ul Abideen Asad> ;The American Journal of Cardiology. 2023 Nov 15
• Psychosocial risk factors and outcomes in patients undergoing catheter ablation for atrial fibrillation.
  Siddharth Agarwal, Muhammad Bilal Munir, Satyam Krishan, Christopher V DeSimone, Abhishek Deshmukh, Stavros Stavrakis, Sunny Po, Sadeer Al-Kindi, Zain Ul Abideen Asad,...> ;Pacing and Clinical Electrophysiology. 2023 Oct 1
• Outcomes of Catheter Ablation for Atrial Fibrillation in Patients With Rheumatic Mitral Valve Disease.
  Siddharth Agarwal, Muhammad Bilal Munir, Harsh Patel, Satyam Krishan, Joshua Payne, Christopher V DeSimone, Abhishek Deshmukh, Stavros Stavrakis, Warren Jackman, Sunny...> ;The American Journal of Cardiology. 2024 Jan 1
• Impact of Frailty on Outcomes of Patients Who Underwent Catheter Ablation for Ventricular Tachycardia.
  Siddharth Agarwal, Harsh P Patel, Justin Z Lee, Zain Ul Abideen Asad, Muhammad Bilal Munir, Mohamed Labedi, Abhishek Deshmukh, Christopher V DeSimone> ;The American Journal of Cardiology. 2023 Nov 1
• Mayo Clinic VT calculator: A practical tool for accurate wide complex tachycardia differentiation.
  Anthony H Kashou, Sarah LoCoco, Matthew R Gardner, Jocelyn Webb, Jacob C Jentzer, Peter A Noseworthy, Christopher V DeSimone, Abhishek J Deshmukh, Samuel J Asirvatham,...> ;Annals of Noninvasive Electrocardiology. 2023 Nov 1
• Catheter ablation of atrial fibrillation in patients with and without hypertrophic cardiomyopathy: systematic review and meta-analysis.
  Fatima M Ezzeddine, Kolade M Agboola, Leslie C Hassett, Ammar M Killu, Freddy Del-Carpio Munoz, Christopher V DeSimone, Gurukripa N Kowlgi, Abhishek J Deshmukh, Konsta...> ;Europace. 2023 Aug 2
• 1 citations
  Outcomes of patients with cancer undergoing percutaneous left atrial appendage occlusion.
  Siddharth Agarwal, Avirup Guha, Muhammad Bilal Munir, Christopher V DeSimone, Abhishek Deshmukh, Zain Ul Abideen Asad> ;Journal of Interventional Cardiac Electrophysiology. 2023 Nov 1
• Impact of psychosocial risk factors on outcomes of patients undergoing catheter ablation for ventricular tachycardia.
  Siddharth Agarwal, Zain Ul Abideen Asad, Joshua Payne, Muhammad Bilal Munir, Abhishek Deshmukh, Christopher V DeSimone> ;Heart Rhythm O2. 2023 Aug 1
• Impact of Atrial Fibrillation on Outcomes in Patients Hospitalized With Nontraumatic Intracerebral Hemorrhage.
  Sahith Reddy Thotamgari, Akhilesh Babbili, Prabandh Bucchanolla, Samarthkumar Thakkar, Harsh P Patel, Maja B Spaseski, Jonathan Graff-Radford, Alejandro A Rabinstein, ...> ;Mayo Clinic Proceedings. Innovations, Quality & Outcomes. 2023 Aug 1
• Complexity analysis of electrical activity during endocardial and epicardial biventricular mapping of ventricular fibrillation.
  Vasanth Ravikumar, Xiangzhen Kong, Nick Y Tan, George Christopolous, Thomas P Ladas, Zhi Jiang, Jason A Tri, Alan M Sugrue, Samuel J Asirvatham, Christopher V DeSimone...> ;Journal of Interventional Cardiac Electrophysiology. 2023 Jul 11
• 1 citations
  Management of Premature Ventricular Complexes in the Outpatient Setting.
  Andrew S Tseng, Gurukripa N Kowlgi, Christopher V DeSimone> ;Mayo Clinic Proceedings. 2023 Jul 1
• 2 citations
  Safety and efficacy of colchicine for the prevention of post-operative atrial fibrillation in patients undergoing cardiac surgery: a meta-analysis of randomized contro...
  Siddharth Agarwal, Christopher W Beard, Jagjit Khosla, Shari Clifton, Muhammad Faraz Anwaar, Asad Ghani, Kassem Farhat, Nikolaos Pyrpyris, Joud Momani, Muhammad Bilal ...> ;Europace. 2023 Jul 4
• Impact of Frailty on In-Hospital Outcomes in Patients Undergoing Atrial Fibrillation Ablation.
  Siddharth Agarwal, Christopher V DeSimone, Abhishek Deshmukh, Muhammad Bilal Munir, Harsh Patel, Zain Ul Abideen Asad, Stavros Stavrakis> ;The American Journal of Cardiology. 2023 Aug 15
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Journal Articles

• Blood Pressure Responses to Endovascular Stimulation: A Potential Therapy for Autonomic Disorders with Vasodilatation  
  Naksuk N, Killu AM, Yogeshwaran V, DeSimone CV, Suddendorf S, Ladewig D, Madhavan M, Cha YM, Kapa S, Asirvatham SJ, J Cardiovasc Electrophysiol, 1/28/2016
• Cardiac Implantable Electronic Device Lead Vegetation and Atrial Fibrillation Ablation: A Case-based Illustration of Peri-Procedural Anticoagulation Management Strategies  
  Lenz CJ, DeSimone CV, Ponamgi SP, Sugrue A, Sinak L, Chandrasekaran K, Packer DL, Asirvatham SJ, J Interv Card Electrophysiol, 1/22/2016
• Ischemic Stroke or Systemic Embolism following Transseptal Ablation of Arrhythmias in Patients with Cardiac Implantable Electronic Devices  
  Madhavan M, Yao X, Sangaralingham LR, Asirvatham SJ, Friedman PA, McLeod CJ, DeSimone CV, Noseworthy PA, J Am Heart Assoc, 1/13/2016
• Innovative Approaches to Assess the Impact and Decrease the Neurological Consequences of Ablation  
  Ponamgi SP, Yasin OZ, Padmanabhan D, DeSimone CV, Asirvatham SJ, Journal of Innovations in Cardiac Rhythm Management, 1/1/2016
• Atrial Fibrillation and Stroke- Increasing Stroke Risk with Intervention  
  DeSimone CV, Madhavan M, Ebrille E, Rabinstein AA, Friedman AA, Asirvatham SJ, Journal of Atrial Fibrillation, 1/1/2014
• Different Strokes  
  Konecny T, DeSimone CV, Sehar N, Asirvatham SJ, Journal of Innovations in Cardiac Rhythm Management, 1/1/2014
• Percutaneous Autonomic Neural Modulation: A Novel Technique to Treat Cardiac Arrhythmia  
  DeSimone CV, Madhavan M, Venkatachalam KL, Knudson MB, Asirvatham SJ, Cardiovasc Revasc Med., 1/1/2013
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Books/Book Chapters

• Catheter ablation of cardiac arrhythmias 
  Chapter: Cardiac anatomy for catheter mapping and ablation of arrhythmias 
  Page 85 - 105Liang JJ, DeSimone CV, Lachman N, Noheria A, Nanda S, Asirvatham SJEditors: Stephen Huang S, Miller JM.Elsevier Saunders, Philadelphia, PAEdition 3rd,2015

Abstracts/Posters

• Direct Pulmonary Vein Ablation Without Stenosis: Chronic Efficacy of a Novel Electroporation Technique
  Witt C, Sugrue A, Padmanabhan D, Vaidya V, Gruba S, Rohl J, Killu A, Naksuk N, DeSimone C, Kapa S, Asirvatham SJ, ACC, 1/1/2018
• Stroke in Patients with Cardiovascular Implantable Electronic Device Infection Undergoing Transvenous Lead Removal
  Lee JZ, Pradyumma A, Pasha AK, C, Tseng AS, Diehl NN, Hodge DO, DeSimone CV, Killu AM, Brady PA, Kancharla K, Kusumoto FM, Srivathsan K, Osborn MJ, Espinosa RE, Rea RF..., HRS, 1/1/2018
• A Novel Means to Successfully Differentiate Wide-Complex Tachycardias Using Mathematically-Synthesized Vectorcardiogram Signals
  Kashou AH, May AM, DeSimone CV, Deshmukh AJ, Noseworthy PA, Minneapolis, MN, 1/1/2018
• Inducible Arrhythmogenicity of Direct Current Electroporation Ablation: Insight from a Series of Acute Canine Studies
  Sugrue A, Witt C, DeSimone CV, Padnanabhan D, Killu A, Naksuk N, Kapa S, Asirvatham SJ, BCVS, 1/1/2017
• Assessment of Catheter Position above or below the Aortic Valve by Evaluation of Characteristics of the Local Electrogram: An Acute Canine Study
  Padmanabhan D, Witt C, Naksuk N, Killu AM, DeSimone CV, Sugrue A, Foxall T, Drakulic B, Ladewig D, Suddendorf S, Powers J, Venkatachalam KL, Asirvatham SJ, BCVS, 1/1/2017
• Use of a Novel Electrogram Filtering Algorithm to Visualize Conduction Tissue Signals in the Ventricle in Sinus Rhythm and Arrhythmia: An Acute Canine Study
  Padmanabhan D, Killu AM, Witt C, Naksuk N, DeSimone CV, Sugrue A, Foxall T, Drakulic B, Ladewig D, Suddendorf S, Powers J, Venkatachalam KL, Asirvatham SJ, BCVS, 1/1/2017
• Novel Insights into the Role of the His-Purkinje System during Electrophysiological Mapping of the Canine Heart in Ventricular Fibrillation
  Asirvatham RS, Tri J, DeSimone CV, Asirvatham SJ, International Dead Seas Symposium (IDSS) on Innovations in Cardiac Arrhythmias and Device Therapy, Tel Aviv, Israel, 1/1/2016
• Beating Heart Validation of Safety and Efficacy of a Percutaneous Pericardiotomy Tool
  Gaba P, Killu AM, Naksuk N, DeSimone CV, Suddendorf S, Powers J, Ladewig D, Lerman L, Borlaug B, Asirvatham SJ, Heart Rhythm, 1/1/2016
• Dose-Response Relationship Between the Direct Current Electroporation and Ablation of Pulmonary Vein Myocardium
  Naksuk N, Killu AM, DeSimone CV, Ladewig DJ, Suddendorf SH, Kapa S, Holmes DR, Asirvatham SJ, Heart Rhythm, 1/1/2016
• Effects of Stepwise Denervation of Stellate Ganglion and Ansa Subclaviae: Novel Insights into Cardiac Sympathetic Denervation from Canine Studies
  DeSimone CV, Wu G, Suddendorf S, Asirvatham R, Asirvatham SJ, Chen PS, Cha YM, Heart Rhythm, 1/1/2016
• An Emerging Non-Thermal Ablation Tool: Electroporation Effectively Abolishes Purkinje Fiber Potentials Without Transmural Myocardial Ablation
  Killu AM, Naksuk N, DeSimone CV, Tri J, Asirvatham R, Maor E, Ladewig D, Suddendorf S, Asirvatham SJ, Heart Rhythm, 1/1/2016
• Development of a Partially Insulated Epicardial Catheter to Confer Directionality during Ablation
  Killu AM, Naksuk N, Syed F, DeSimone CV, Gaba P, Ladewig D, Suddendorf S, Danielson A, Lukasova M, Wolf J, Leinveber P, Novak M, Starek Z, Kara T, Bruce C, Friedman PA..., Heart Rhythm, 1/1/2016
• Epicardial Electroporation Effectively Ablations Myocardium without Compromising Coronary Artery Patency
  Killu AM, Naksuk N, DeSimone CV, Tri J, Asirvatham R, Maor E, Ladewig D, Suddendorf S, Asirvatham SJ, Heart Rhythm, 1/1/2016
• Evaluation of a Novel Defibrillation Unit with Dual-Vector, Quadriphasic Waveform Capabilities: Towards a Miniaturized Defibrillator
  Okamura H, DeSimone CV, Killu A, Gilles EJ, Tri J, Asirvatham R, Ladewig DJ, Suddendorf SH, Powers JM, Wood-Wentz CM, Gray PD, Raymond DM, Bruce CJ, Asirvatham SJ, Fri..., Heart Rhythm, 1/1/2016
• Enhanced Electrophysiology Recording System
  Killu AM, Naksuk N, Venkatachalam KL, DeSimone CV, Fakhar S, Foxall T, Vlajinic B, Drakulic BS, Suddendorf S, Powers J, Ladewig DJ, Asirvatham SJ, IEEE Engineering in Medicine and Biology Society, 1/1/2016
• Non-Invasive Remote Monitoring of Potassium in Dialysis Patients Using an Internet-Based Wireless ECG Patch
  Attia Z, Dillon JJ, DeSimone CV, Sapir Y, Somers VK, Dugan JL, Ackerman, Asirvatham SJ, Bukartyk J, Scott CG, Ladewig DJ, Seifert G, Gibson P, Geva A, Sadot D, Friedma..., American Heart Association Scientific Sessions, 1/1/2016
• Beta-hemolytic Streptococcal Infective Endocarditis: Mayo Clinic Experience 2000-2014
  El Rafei A, DeSimone DC, DeSimone CV, Steckelberg JM, Sohail MR, Wilson WR, Baddour LM, Mayo Clinic 12th Annual Infectious Diseases Fellows Forum, Minneapolis, MN, 1/24/2015
• The Impact of Diabetes Mellitus on Outcomes of Streptococcus agalactiae Infective Endocarditis
  El Rafei A, DeSimone DC, DeSimone CV, Steckelberg JM, Sohail MR, Wilson WR, Baddour LM, ICAAC, San Diego, CA, 1/18/2015
• Beta Hemolytic Streptococcal Infective Endocarditis: Clinical presentation, Management, and Outcomes
  El Rafei A, DeSimone DC, DeSimone CV, Lahr BD, Steckelberg JM, Sohail MR, Wilson WR, Baddour LM, IDweek, San Diego, CA, 1/8/2015
• Catheter-Based Intervention for Pulmonary Vein Stenosis Due to Fibrosing Mediastinitis
  Ponamgi S, DeSimone CV, Lenz CJ, Coylewright M, Asirvatham SJ, Holmes DR, Packer DL, Heart Rhythm, 1/1/2015
• Reduction in ventricular fibrillation following surgical correction of bileaflet mitral valve prolapse
  Vaidya V, DeSimone CV, Naksuk N, Syed F, Ackerman MJ, Ponamgi S, Suri R, Noseworthy PA, Asirvatham SJ, Heart Rhythm, 1/1/2015
• Coincidental impact of transcatheter patent foramen ovale closure on migraine with and without aura - a comprehensive meta-analysis
  Kanwar SM, Noheria A, DeSimone C, Rabinstein A, Asirvatham S, Headache, 1/1/2015
• Risk of Stroke or Systemic Embolism After Transseptal Ablation in Patients With Implanted Cardiac Devices
  Noseworthy P, Madhavan, DeSimone C, McLeod, Sangaralingham L, Asirvatham S, Yao X, Circulation, 1/1/2015
• Beta Hemolytic Streptococcus Infective Endocarditis: Factors Associated with Early Mortality
  El Rafei A, DeSimone DC, DeSimone CV, Lahr BD, Steckelberg JM, Sohail MR, Wilson WR, Baddour LM, Open forum Infectious Disease �IDweek�, 1/1/2015
• Five-Year Mortality of Native versus Prosthetic Valve Endocarditis in a Population-Based Cohort
  El Rafei A, DeSimone DC, DeSimone CV, Steckelberg JM, Sohail MR, Wilson WR, Baddour LM, Open forum Infectious Disease �IDweek�, 1/1/2015
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Lectures

• Great Cases- Atriofascular Pathways: ECG clues and Mapping and Ablation Str 
  1/1/2018
• Essential Anatomy for Ventricular Tachycardia 
  1/1/2018
• Case Studies in Disease Management: Anatomy and Arrhythmias 
  1/1/2017
• Q/A for how to succeed after the MD/PhD program- insights and perspective for residency and fellowship 
  1/9/2016
• Fundamentals of EKG and Practical Interpretation 
  1/1/2016
• Thromboembolic Risk of Right Sided Implantable Devices 
  Tel Aviv, Israel - 1/1/2016
• Potential for Enhancing Post-MI Risk Stratification and Therapy with Cardiac MRI 
  1/1/2016
• Case Studies in Disease Management 
  1/1/2016
• Cardiac Physiology 
  1/1/2015
• Clinically Oriented Pericardiocentesis 
  1/1/2015
• Basic 12 lead Interpretation 
  1/1/2015
• Patent Foramen Ovale in Patients with Cardiac Implantable Electronic Devices; Trials and Tribulations in Defining Practice 
  1/1/2015
• Using Signal-Averaged ECG to Correlate Electrocardiographic Changes with Potassium Changes in Patients Undergoing Hemodialysis: A Novel �Bloodless� Blood Test 
  Mayo Clinic, Rochester, MN - 1/14/2014
• Short and Long-Term ECG Changes after Left Cardiac Sympathetic Denervation in Patients with Long QT Syndrome 
  San Francisco, CA - 1/1/2014
• Patent Foramen Ovale in Patients with Cardiac Implantable Electronic Devices: a High Risk Population That May Benefit from Device Closure? 
  Mayo Clinic, Rochester, MN - 1/4/2013
• Mayo Clinic Department of Internal Medicine Morbidity and Mortality Systems Audit 
  Rochester, MN - 1/14/2012
• Patent Foramen Ovale and Risk of Stroke in Patients with Transvenous Pacemakers and Defibrillators 
  Los Angeles, CA - 1/1/2012
• What is the Action for Non-Compaction? Diagnosis and Management of Left Ventricular Non-Compaction Cardiomyopathy 
  Minneapolis, MN - 1/4/2011
• Binding, Specificity, and Gating Studies of HpTx2 with Kv4.3; the Potassium Channel Responsible for the Cardiac Transient Outward Current Ito 
  Chicago, IL - 1/23/2010
• A Case of Symptomatic Non-Sustained Ventricular Tachycardia with an Unusual Structure as the Underlying Etiology 
  Minneapolis, MN - 1/5/2010
• HpTx2 Binding and Gating Modification of Kv4 channels Are Dependent on Distinct Amino Acids in S3b 
  Buffalo, NY - 1/17/2008
• Binding Studies of the Gating Modifier Toxin rHpTx2 with Kv4.3 
  Rochester, NY - 1/1/2008
• Molecular Determinants of rHpTx2GS Interaction with Kv4.3 
  Chicago, IL - 1/13/2007
• Binding Studies of the Gating Modifier rHpTx2 on Kv4.3 
  Rochester, NY - 1/12/2007
• In Vitro Characterization of the Apoptotic Process Using Photoactive Porphyrins in a Cell-Free Nuclear Extract 
  Geneseo, NY, 2003; Ithaca, NY, 2003 - 1/1/2003
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Other

• New Approach to Chronic Resynchronization Therapy: CRT without LV lead. Invited Commentary 
  DeSimone CV and Asirvatham SJ, Cardiac Rhythm News
  http://www.cxvascular.com/crn-features/cardiac-rhythm-news---features/new-approach-to-cardiac-resynchronisation-therapy-crt-without-left-ventricular-lead
  1/25/2014
• Doctoral Dissertation: Binding Studies of the Gating Modifier toxin HpTx2 with Kv4.3 
  DeSimone CV, The State University at Buffalo School of Medicine and Biomedical Sciences
  1/17/2008
• Porphyrin localization and Apoptosis induction in RIF cells in culture. The Miami Nature Biotechnology Winter Symposium: 50 Years on: From the double helix to molecula... 
  DeSimone CV and Greene RS, Proceedings of the Miami Nature Biotechnology Winter Symposium Short Reports
  http://www.med.miami.edu/mnbws/x26.xml
  1/1/2003
• In Vitro Characterization of the Apoptotic Process Using Photoactive Porphyrins in a Cell-Free Nuclear Extract 
  DeSimone CV, Niagara University
  1/1/2003
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