ChristopherMichaelHorvatMD

PubMed

• 1 citations
  Sedation Research in Critically Ill Pediatric Patients: Proposals for Future Study Design From the Sedation Consortium on Endpoints and Procedures for Treatment, Educa...
  Biagas, K., Shawn S Jackson, Jennifer J Lee, William M Jackson, Jerri C Price, Sue R Beers, John W Berkenbosch, Katherine V Biagas, Robert H Dworkin, Constance S Houck...> ;Pediatric Critical Care Medicine. 2024 Apr 1
• EMERGENCE OF A TECHNOLOGY-DEPENDENT PHENOTYPE OF PEDIATRIC SEPSIS IN A LARGE CHILDREN'S HOSPITAL.
  Zachary Aldewereld, Christopher Horvat, Joseph A Carcillo, Gilles Clermont> ;Shock. 2024 Jan 1
• 4 citations
  High-Flow Nasal Cannula Use and Patient-Centered Outcomes for Pediatric Bronchiolitis.
  Christopher M. Horvat, Jonathan H. Pelletier> ;JAMA Network Open. 2021 Oct 1
• 2 citations
  Application of the Improving Pediatric Sepsis Outcomes Definition for Pediatric Sepsis to Nationally Representative Emergency Department Data
  Sriram Ramgopal, Mark D. Adler, Christopher M. Horvat> ;Pediatric Quality & Safety. 2021 Sep 1
• 2 citations
  A Trial of Albuterol Should Still Be Considered for Children With Severe Bronchiolitis.
  Christopher M. Horvat, Jonathan H. Pelletier> ;JAMA Pediatrics. 2021 Nov 1
• 51 citations
  Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial.
  Yaseen M. Arabi, Anthony C. Gordon, Lennie P. G. Derde, Alistair Nichol, Srinivas Murthy, Farah Al Beidh, Djillali Annane, Lolowa Al Swaidan, Abi Beane, Richard Beasle...> ;Intensive Care Medicine. 2021 Jul 12
• 3 citations
  Multidrug-resistant organisms: A significant cause of severe sepsis in pediatric intestinal and multi-visceral transplantation.
  Alicia M. Alcamo, Mira K. Trivedi, Carly Dulabon, Christopher M. Horvat, Geoffrey J. Bond, Joseph A. Carcillo, Michael Green, Marian G. Michaels, Rajesh K. Aneja> ;American Journal of Transplantation. 2021 Jul 10
• 3 citations
  Neurological Complications Acquired During Pediatric Critical Illness: Exploratory "Mixed Graphical Modeling" Analysis Using Serum Biomarker Levels.
  Vineet K. Raghu, Christopher M. Horvat, Patrick M. Kochanek, Ericka L. Fink, Panayiotis V. Benos, Alicia K. Au, Clark, R. S., Robert S. B. Clark> ;Pediatric Critical Care Medicine. 2021 Jun 1
• 13 citations
  Forecast modeling to identify changes in pediatric emergency department utilization during the COVID-19 pandemic
  Sriram Ramgopal, Jonathan H. Pelletier, Jaskaran Rakkar, Christopher M. Horvat> ;The American Journal of Emergency Medicine. 2021 May 21
• 3 citations
  Clinical Deterioration and Neurocritical Care Utilization in Pediatric Patients With Glasgow Coma Scale Score of 9-13 After Traumatic Brain Injury: Associations With P...
  Elif Soysal, Christopher M. Horvat, Dennis W. Simon, Michael S. Wolf, Elizabeth C. Tyler-Kabara, Barbara A. Gaines, Patrick M. Kochanek, Hülya Bayır, Clark, R. S., Rob...> ;Pediatric Critical Care Medicine. 2021 May 12
• 849 citations
  Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.
  , Anthony C Gordon, Paul R Mouncey, Farah Al-Beidh, Kathryn M Rowan, Alistair D Nichol, Yaseen M Arabi, Djillali Annane, Abi Beane, Wilma van Bentum-Puijk, Lindsay R B...> ;The New England Journal of Medicine. 2021 Apr 22
• 50 citations
  Blood Biomarkers for Detection of Brain Injury in COVID-19 Patients.
  Steven T. DeKosky, Patrick M. Kochanek, Alex B. Valadka, Robert S. B. Clark, Sherry H.-Y. Chou, Alicia K. Au, Christopher M. Horvat, Ruchira M. Jha, Rebekah Mannix, St...> ;Journal of Neurotrauma. 2021 Jan 1
• 4 citations
  Opportunities for Regulatory Changes to Promote Pediatric Device Innovation in the United States: Joint Recommendations From Pediatric Innovator Roundtables
  Terence D. Sanger, Anthony C. Chang, William Feaster, Sharief Taraman, Nadine B. Afari, Debra Beauregard, Brent A. Dethlefs, Tiffani Ghere, Mustafa H. Kabeer, George T...> ;IEEE Journal of Translational Engineering in Health and Medicine. 2021 Jun 25
• 30 citations
  Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients
  Laura B. Ramsey, Henry H. Ong, Jonathan S. Schildcrout, Yaping Shi, Leigh Anne Tang, J. Kevin Hicks, Nihal El Rouby, Larisa H. Cavallari, Sony Tuteja, Christina L. Aqu...> ;JAMA Network Open. 2020 Dec 1
• Merging Pediatric Index of Mortality (a physiologic instability measure), lactate, and Systemic Inflammation Mortality Risk to better predict outcome in pediatric sepsis.
  Christopher M. Horvat, Dennis W. Simon, Zachary Aldewereld, Idris V R Evans, Rajesh K. Aneja, Joseph A. Carcillo> ;Jornal De Pediatria. 2021 Jul 2
• 13 citations
  Intracranial and Cerebral Perfusion Pressure Thresholds Associated With Inhospital Mortality Across Pediatric Neurocritical Care.
  Kendra Woods, Christopher M. Horvat, Sajel Kantawala, Dennis W. Simon, Jaskaran Rakkar, Patrick M. Kochanek, Robert S. B. Clark, Alicia K. Au> ;Pediatric Critical Care Medicine. 2021 Feb 1
• 1 citations
  Can Computer Decision Support Help Us Follow Our Own Rules in Pediatric Acute Respiratory Distress Syndrome
  Jonathan H. Pelletier, Christopher M. Horvat> ;Pediatric Critical Care Medicine. 2020 Nov 1
• 26 citations
  Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision.
  Clark, R. S., Patrick M. Kochanek, Travis C. Jackson, Ruchira M. Jha, Robert S. B. Clark, David O. Okonkwo, Hülya Bayır, Samuel M. Poloyac, Amy K. Wagner, Philip E. Em...> ;Journal of Neurotrauma. 2020 Oct 28
• 25 citations
  A qualitative research framework for the design of user-centered displays of explanations for machine learning model predictions in healthcare
  Amie J Barda, Christopher M. Horvat, Harry Hochheiser> ;BMC Medical Informatics and Decision Making. 2020 Oct 8
• 8 citations
  Maximum Pao 2 in the First 72 Hours of Intensive Care Is Associated With Risk-Adjusted Mortality in Pediatric Patients Undergoing Mechanical Ventilation
  Jonathan H. Pelletier, Sriram Ramgopal, Alicia K. Au, Robert S. B. Clark, Christopher M. Horvat> ;Critical Care Explorations. 2020 Sep 14
• 2 citations
  Machine learning approaches for the identification of children at low risk of intra-abdominal injury requiring intervention.
  Sriram Ramgopal, Christopher M. Horvat> ;The Journal of Trauma and Acute Care Surgery. 2021 May 1
• 545 citations
  Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
  Derek C. Angus, Lennie P. G. Derde, Farah Al-Beidh, Djillali Annane, Yaseen M. Arabi, Abi Beane, Wilma van Bentum-Puijk, Lindsay R. Berry, Zahra Bhimani, Marc J. M. Bo...> ;JAMA. 2020 Oct 6
• 30 citations
  Machine Learning To Predict Serious Bacterial Infections in Young Febrile Infants
  Sriram Ramgopal, Christopher M. Horvat, Naveena Yanamala, Elizabeth R. Alpern> ;Pediatrics. 2020 Sep 1
• 12 citations
  Association of triage hypothermia with in-hospital mortality among patients in the emergency department with suspected sepsis.
  Sriram Ramgopal, Christopher M. Horvat, Mark D. Adler> ;Journal of Critical Care. 2020 Jul 16
• 5 citations
  Assessment of Dynamic Intracranial Compliance in Children with Severe Traumatic Brain Injury: Proof-of-Concept
  Michael S. Wolf, Jaskaran Rakkar, Christopher M. Horvat, Dennis W. Simon, Patrick M. Kochanek, Gilles Clermont, Robert S. B. Clark> ;Neurocritical Care. 2021 Feb 1
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Journal Articles

• Trends in US Pediatric Hospital Admissions in 2020 Compared with the Decade Before the COVID-19 Pandemic  
  Jonathan H Pelletier, Jaskaran Rakkar, Alicia K Au, Christopher M Horvat, JAMA Network Open
• Prescribing Prevalence of Medications with Potential Genotype-Guided Dosing in Pediatric Patients  
  Amber L Beitelshees, Philip E Empey, Christopher M Horvat, Jeffrey R Bishop, JAMA Network Open
• Taking Predictive Analytics to Point-of-Care  
  Horvat CM, Clark RS, Critical Care Connections, 1/1/2016
• Evaluation of Electronic Medical Record Vital Sign Data Versus a Commercially Available Acuity Score in Predicting Need for Critical Intervention at a Tertiary Childre...  
  Da Silva YS, Hamilton MF, Horvat CM, Fink EL, Palmer F, Nowalk AJ, et al, Pediatr Crit Care Med, 1/1/2015
• Liquid fluorocarbon lavage to clear thrombus from the distal airways after severe pulmonary hemorrhage requiring extracorporeal life support (ECLS)  
  Horvat CM, Carcillo JA, Dezfulian C, Respiratory Medicine Case Reports, 1/1/2015
• Thiamin Deficiency as a Cause of Persistent Hyperlactatemia in a Parenteral Nutrition-Dependent Patient  
  Da Silva YS, Horvat CM, Dezfulian C, JPEN J Parenter Enteral Nutr, 1/1/2015
• Bringing attention into higher focus within the traumatic brain injury research agenda  
  Horvat CM, Bell MJ, Transl Pediatr, 1/1/2015
• Searching for the Brain’s Canary in the Coal Mine  
  Horvat CM, Fink EL, Crit Care Med, 1/1/2015
• A persistent pesticide residue and the unusual catalytic proficiency of a dehalogenating enzyme  
  Horvat CM, Wolfenden RV, Proc Natl Acad Sci USA, 1/8/2005
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Abstracts/Posters

• Post-resuscitation GCS is Associated with Outcome in Pediatric Traumatic Brain Injury
  Horvat CM, Bell M, Wisniewski S, Balasubramani G, Kochanek P, Beers S, Danielle Brown S, Adelson P, Soc. Crit. Care Med. Annual Congress, Honolulu, HI, 1/25/2017
• Pharmacogenomic-based Evaluation of Fentanyl Requirements in Diagnostically Diverse PICU Patients
  Horvat CM, Au A, Empey P, Conley Y, Clark RS, Soc. Crit. Care Med. Annual Congress, Honolulu, HI, 1/25/2017
• Prospective Evaluation of the Pediatric Rothman Index as a Measure of Pediatric Inpatient Acuity
  Horvat CM, Hamilton MF, Almasi GS, Palmer F, Valenta C, Kyper C, Rothman MJ, and Clark RS, Health Services Research Session, Fink Scholar Day, Pittsburgh, PA, 1/26/2016
• Retrospective Evaluation of the Pediatric Rothman Index as a Predictor of Cardiac Arrest in a CICU
  Horvat CM, Sanchez-de-Toledo J, Wilson S, Palmer F, Rothman MJ, Finn S, Almasi GS, and Munoz R, Soc. Crit. Care Med. Annual Congress, Orlando, FL, 1/24/2016
• Prospective Evaluation of the Pediatric Rothman Index as a Measure of Pediatric Inpatient Acuity
  Horvat CM, Hamilton MF, Almasi GS, Palmer F, Valenta C, Kyper C, Rothman MJ, and Clark RS, Soc. Crit. Care Med. Annual Congress, Orlando, FL, 1/24/2016
• Presenting Glasgow Coma Scale score is associated with outcome in pediatric severe traumatic brain injury: a secondary analysis from a randomized, controlled trial of ...
  Horvat CM, Bell, MJ, Wisniewski S, Balasubramani G, Kochanek P, Beers S, Brown S, and Adelson P, Safar Symposium, Pittsburgh, PA, 1/17/2016
• A Commercially Available Acuity Score is a Predictor of Acute Care to Intensive Care Transfer
  Horvat CM, Suresh S, Palmer F, Hamilton MF, Almasi GS, Ashline J, Rothman MJ, Clark RS, World Congress on Pediatric Intensive and Critical Care, Toronto, Ontario, Canada, 1/8/2016
• Implementation of Condition E (Early, EMR Based Recognition of Clinical Deterioration) to Enhance Intervention Timeliness and Match Resource Intensity at a Tertiary Ca...
  Horvat CM, Palmer F, Srinivasan S, Clark B, Pediatric Academic Societies, Baltimore, MD, 1/3/2016
• The Pediatric Critical Care Ultrasound Initiative
  Horvat CM, Newmyer RE, Browning M, Aneja R, The Beckwith Institute Grant Symposium, Pittsburgh, PA, 1/23/2015
• A survey assessing PICU providers’ knowledge of the cost of care
  Horvat CM, Thompson AE, Soc. Crit. Care Med. Annual Congress, Phoenix, AZ, 1/17/2015
• Early Experience Developing and Implementing a Pediatric Critical Care Ultrasound Curriculum
  Horvat CM, Newmyer RE, Browning M, Hamilton MF, Clark RS, Aneja R, Quality and Safety Session, Fink Scholar Day, Pittsburgh, PA, 1/3/2015
• Using EMR data to Detect Emergent Conditions at a Pediatric Hospital
  Horvat CM, Hamilton MF, Palmer F, Clark RS, Rothman M, Quality and Safety Session, Fink Scholar Day, Pittsburgh, PA, 1/3/2015
• The unknown cost of pediatric critical care: A survey assessing PICU providers’ awareness of the cost of care
  Horvat CM, Thompson AE, Quality and Safety Session, Fink Scholar Day; Rangos Research Symposium, Pittsburgh, PA, 1/3/2015
• Using EMR data to detect emergent conditions at a pediatric hospital
  Horvat CM, Hamilton M., Palmer F., Clark RS, Rothman M, Institute for Healthcare Improvement (IHI) Scientific Symposium, Orlando, FL, 1/8/2014
• Exploring the Relationship between Extracellular Adenyl Purines and Neutrophils in the Cystic Fibrosis Lung
  Horvat CM, Esther, CR, University of North Carolina School of Medicine Student Research Day, 1/1/2008
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Lectures

• Thoracic ultrasound 
  Pittsburgh, PA - 1/11/2016
• Point-of-Care Ultrasound in Pediatric Critical Care 
  Pittsburgh, PA - 1/29/2015
• Condition E: Early, EMR-Based Recognition of Clinical Deterioration 
  Pittsburgh, PA - 1/22/2015
• Early, EMR-Based Recognition of Clinical Deterioration 
  Pittsburgh, PA - 1/15/2015
• Examining the Bill: An introduction to the cost of care 
  Seattle, WA - 1/1/2013
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