ChristopherNikolausSchmicklMD

PubMed

• The Effect of Obesity on Sleep Apnea Pathogenesis Differs in Women vs Men: Multiple Mediation Analyses in the Retrospective SNOOzzzE Cohort.
  Stephanie White, Steven Luu, Zihan Chen, Raichel Alex, Scott A Sands, Robert L Owens, Brandon Nokes, Jeremy E Orr, Brian S Wojeck, Atul Malhotra, Christopher N Schmickl> ;Journal of Applied Physiology. 2024 Apr 25
• Pathogenesis of sleep disordered breathing in the setting of opioid use: A multiple mediation analysis using physiology.
  Eli Gruenberg, Traci Marin, Scott A Sands, Raichel M Alex, Robert L Owens, Jeremy E Orr, Atul Malhotra, Christopher N Schmickl> ;Sleep. 2024 Apr 12
• Treatment of Sleep Apnea and Reduction in Blood Pressure: The Role of Heart Rate Response and Hypoxic Burden.
  Ludovico Messineo, Gonzalo Labarca, Wen-Hsin Hu, Neda Esmaeili, Daniel Vena, Laura Gell, Nicole Calianese, Daniel J Gottlieb, Andrew Wellman, Susan Redline, Ali Azarba...> ;Hypertension. 2024 May 1
• 2 citations
  Loop Gain as a Predictor of Blood Pressure Response in Patients Treated for Obstructive Sleep Apnea: Secondary Analysis of a Clinical Trial.
  Christopher N Schmickl, Jeremy E Orr, Scott A Sands, Raichel M Alex, Ali Azarbarzin, Lana McGinnis, Stephanie White, Diego R Mazzotti, Brandon Nokes, Robert L Owens, D...> ;Annals of the American Thoracic Society. 2024 Feb 1
• 1 citations
  Effectiveness of long-term noninvasive ventilation measured by remote monitoring in neuromuscular disease.
  Jeremy E Orr, Kenneth Chen, Florin Vaida, Christopher N Schmickl, Chamindra G Laverty, John Ravits, Daniel Lesser, Rakesh Bhattacharjee, Atul Malhotra, Robert L Owens> ;ERJ Open Research. 2023 Sep 1
• 41 citations
  International Consensus Statement on Obstructive Sleep Apnea.
  Creamer, J. L., Jolie L Chang, Andrew N Goldberg, Jeremiah A Alt, Alzoubaidi Mohammed, Liza Ashbrook, Dennis Auckley, Indu Ayappa, Hira Bakhtiar, José E Barrera, Betha...> ;International Forum of Allergy & Rhinology. 2023 Jul 1
• 2 citations
  POINT:: Are OSA Phenotypes Clinically Useful? Yes.
  Bradley A Edwards, Amy S Jordan, Christopher N Schmickl, Robert L Owens> ;Chest. 2023 Jan 1
• Rebuttal From Dr Edwards et al.
  Bradley A Edwards, Amy S Jordan, Christopher N Schmickl, Robert L Owens> ;Chest. 2023 Jan 1
• 1 citations
  Diagnostic performance of screening tools for the detection of obstructive sleep apnea in people living with HIV.
  Christopher N Schmickl, Naa-Oye Bosompra, Pamela N DeYoung, Dillon Gilbertson, Jeremy E Orr, Atul Malhotra, Igor Grant, Sonia Ancoli-Israel, Maile Karris Young, Robert...> ;Journal of Clinical Sleep Medicine. 2022 Jul 1
• 1 citations
  Obesity Hypoventilation Syndrome and Postsurgical Outcomes in a Bariatric Surgery Cohort.
  Janna R Raphelson, Christopher N Schmickl, Christine Sonners, Kimberly Kreitinger, Eduardo Grunvald, Santiago Horgan, Atul Malhotra> ;Obesity Surgery. 2022 Jul 1
• 1 citations
  Drug Therapy for Obstructive Sleep Apnea: Are We There Yet?
  Christopher N Schmickl, Bradley A Edwards, Atul Malhotra> ;American Journal of Respiratory and Critical Care Medicine. 2022 Jun 15
• 2 citations
  The impact of daytime transoral neuromuscular stimulation on upper airway physiology - A mechanistic clinical investigation.
  Brandon Nokes, Christopher N Schmickl, Rebbecca Brena, Nana Naa-Oye Bosompra, Dillon Gilbertson, Scott A Sands, Rakesh Bhattacharjee, Dwayne L Mann, Robert L Owens, At...> ;Physiological Reports. 2022 Jun 1
• 3 citations
  Point-of-care prediction model of loop gain in patients with obstructive sleep apnea: development and validation.
  Christopher N Schmickl, Jeremy E Orr, Paul Kim, Brandon Nokes, Scott Sands, Sreeganesh Manoharan, Lana McGinnis, Gabriela Parra, Pamela DeYoung, Robert L Owens, Atul M...> ;BMC Pulmonary Medicine. 2022 Apr 25
• 2 citations
  Pathogenesis of obstructive sleep apnea in people living with HIV.
  Jeremy E. Orr, Bradley A. Edwards, Christopher N. Schmickl, Maile Y. Karris, Pamela N. DeYoung, Chantal Darquenne, Rebecca J. Theilmann, Sonia Jain, Atul Malhotra, Cha...> ;Journal of Applied Physiology. 2021 Oct 21
• 14 citations
  Effects of acetazolamide on control of breathing in sleep apnea patients: Mechanistic insights using meta-analyses and physiological model simulations.
  Christopher N. Schmickl, Shane A. Landry, Jeremy E. Orr, Brandon Nokes, Bradley A. Edwards, Atul Malhotra, Robert L. Owens> ;Physiological Reports. 2021 Oct 1
• 48 citations
  Silent hypoxaemia in COVID-19 patients.
  Tatum S. Simonson, Tracy L. Baker, Robert B. Banzett, Tammie Bishop, Jerome A. Dempsey, Jack L. Feldman, Patrice G. Guyenet, Emma J. Hodson, Gordon S. Mitchell, Esteba...> ;The Journal of Physiology. 2021 Feb 1
• 1 citations
  ATS Core Curriculum 2020. Adult Sleep Medicine.
  Shazia Jamil, Robert L. Owens, Melissa C. Lipford, Shirin Shafazand, R. Marron, Maria Elena Vega Sanchez, Michael T. Lam, Bernie Y. Sunwoo, Christopher N. Schmickl, Je...> ;ATS Scholar. 2020 Dec 30
• 30 citations
  Acetazolamide for OSA and Central Sleep Apnea: A Comprehensive Systematic Review and Meta-Analysis
  Christopher N. Schmickl, Shane A. Landry, Jeremy E. Orr, Kazuo Chin, Kimihiko Murase, Johan Verbraecken, Shahrokh Javaheri, Bradley A. Edwards, Robert L. Owens, Atul M...> ;Chest. 2020 Dec 1
• 9 citations
  The Arousal Threshold as a Drug Target to Improve Continuous Positive Airway Pressure Adherence: Secondary Analysis of a Randomized Trial.
  Christopher N. Schmickl, Christopher J. Lettieri, Jeremy E. Orr, Pamela N. DeYoung, Bradley A. Edwards, Robert L. Owens, Atul Malhotra> ;American Journal of Respiratory and Critical Care Medicine. 2020 Dec 1
• 11 citations
  Screening for Obstructive Sleep Apnea in a Diverse Bariatric Surgery Population
  Kimberly Y Kreitinger, Macy Mei Sze Lui, Robert L. Owens, Christopher N. Schmickl, Eduardo Grunvald, Santiago Horgan, Janna R Raphelson, Atul Malhotra> ;Obesity. 2020 Nov 1
• 6 citations
  Effect of Venlafaxine on Apnea-Hypopnea Index in Patients With Sleep Apnea: A Randomized, Double-Blind Crossover Study.
  Christopher N. Schmickl, Yanru Li, Jeremy E. Orr, Rachel Jen, Scott A. Sands, Bradley A. Edwards, Pamela N. DeYoung, Robert L. Owens, Atul Malhotra> ;Chest. 2020 Aug 1
• 17 citations
  Optimizing B-lines on lung ultrasound: an in-vitro to in-vivo pilot study with clinical implications
  Christopher N. Schmickl, Aravind A. Menon, Rajanigandha Dhokarh, Bhavna Seth, Frank Schembri> ;Journal of Clinical Monitoring and Computing. 2020 Apr 1
• 47 citations
  Side effects of acetazolamide: a systematic review and meta-analysis assessing overall risk and dose dependence
  Christopher N. Schmickl, Robert L. Owens, Jeremy E. Orr, Bradley A. Edwards, Atul Malhotra> ;BMJ Open Respiratory Research. 2020 Apr 1
• 8 citations
  Contemporary Concise Review 2019: Sleep and ventilation
  Bernie Y. Sunwoo, Christopher N. Schmickl, Atul Malhotra> ;Respirology. 2020 Feb 11
• 13 citations
  Pathogenesis of obstructive sleep apnea in individuals with the COPD + OSA Overlap syndrome versus OSA alone.
  Jeremy E. Orr, Christopher N. Schmickl, Bradley A. Edwards, Pamela N. DeYoung, Rebbecca Brena, Xiaoying Sun, Sonia Jain, Atul Malhotra, Robert L. Owens> ;Physiological Reports. 2020 Feb 1
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Journal Articles

• Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN): Evolution of a Content Management System for Point-Of-Care Clinical Decision Support  
  A Barwise, L Garcia-Arguello, Y Dong, M Hulyalkar, M Vukoja, M Schultz, N Adhikari, B Bonneton, O Kilickaya, R Kashyap, O Gajic, C Schmickl, BMC Medical Informatics and Decision Making, 1/1/2016
• Development and validation of clinical performance assessment in simulated medical emergencies: an observational study  
  A Erdogan, Y Dong, X Chen, C Schmickl, RA Sevilla Berrios, LY Garcia Arguello, R Kashyap, O Kilickaya, B Pickering, O Gajic, JC O'Horo, BMC Emerg Med, 1/1/2016
• Male-predominant plasma transfusion strategy for preventing transfusion-related acute lung injury: a systematic review  
  C Schmickl, S Mastrobuoni, F Filippidis, S Shah, J Radic, M Murad, P Toy, O Gajic, Critical Care Medicine, 1/1/2015
• Comparison of Hospital Mortality and Long-term Survival in Patients With Acute Lung Injury/ARDS vs Cardiogenic Pulmonary Edema  
  C Schmickl, M Biehl, G Wilson, O Gajic, Chest, 1/1/2015
• Decision Support Tool for Differential Diagnosis of Acute Respiratory Distress Syndrome (ARDS) vs Cardiogenic Pulmonary Edema (CPE): a Prospective Validation and Meta-...  
  C Schmickl, S Pannu, M Al-Qadi, A Alsara, R Kashyap, R Dhokarh, V Herasevich, O Gajic, Critical Care, 1/1/2014
• Customized reference ranges for laboratory values decrease false positive alerts in intensive care unit patients  
  O Kilickaya, C Schmickl, A Ahmed, J Pulido, J Onigkeit, K Kashani, O Gajic, V Herasevich, B Pickering, PLOS One, 1/1/2014
• A survey on critical care resources and practices in lowand middle-income countries  
  M Vukoja, E Riviello, S Gavrilovic, N Adhikari, R Kashyap, S Bhagwanjee, O Gajic, O Kilickaya, CERTAIN investigators, Glob Heart, 1/1/2014
• Drug-associated acute lung injury: a population-based cohort study  
  R Dhokarh, G Li, C Schmickl, R Kashyap, J Assudani, AH Limper, O Gajic, Chest, 1/1/2012
• Decision Support Tool for Early Differential Diagnosis of Acute Lung Injury and Cardiogenic Pulmonary Edema in Medical Critically-ill Patients  
  C Schmickl, K Shahjehan, G Li, R Dhokarh, R Kashyap, C Janish, A Alsara, A Jaffe, R Hubmayr, O Gajic, Chest, 1/1/2011
• The Accuracy and Efficiency of Electronic Screening for Recruitment Into a Clinical Trial on COPD  
  C Schmickl, M Li, G Li, M Wetzstein, V Herasevich, O Gajic, RP Benzo, Respiratory Medicine, 1/1/2011
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Abstracts/Posters

• Optimizing Ultrasound Settings for B-Lines on Lung Ultrasound - an In-Vitro Pilot Study
  C Schmickl, AA Menon, F Schembri, ATS, Washington, DC, 1/1/2017
• Development and validation of a skill assessment tool for medical emergencies in a simulation center
  A Erdogan, Y Dong, X Chen, C Schmickl, R Sevilla-Berrios, R Kashyap, O Gajic, J O’Horo, Society of Critical Care Medicine, Phoenix, AZ, 1/1/2015
• Prompting with electronic checklist improves clinician performance in medical emergencies: high fidelity simulation study
  R Sevilla-Berrios, J O’Horo, C Schmickl, A Erdogan, X Chen, L Garcia-Arguello, Y Dong, O Gajic, Society of Critical Care Medicine conference, Phoenix, AZ, 1/1/2015
• Male-Predominant Plasma Transfusion Strategy for Preventing Transfusion-Related Acute Lung Injury (TRALI): a Systematic Review
  C Schmickl, S Mastrobuoni, FT Filippidis, S Shah, J Radic, MH Murad, P Toy, O Gajic, American Thoracic Society Meeting, San Diego, CA, 1/1/2014
• Prospective Validation of a Decision Support Tool for immediate Prediction of Acute Lung Injury vs Cardiogenic Pulmonary Edema
  C Schmickl, S Pannu, M Al-Qadi, A Alsara, R Kashyap, O Gajic, American Thoracic Society Meeting, San Diego, CA, 1/1/2014
• The different Contributions of various Parameters to the Differential Diagnosis of Acute Lung Injury versus Cardiogenic Pulmonary Edema
  C Schmickl, K Shahjehan, G Li, R Cartin-Ceba, O Gajic, American Thoracic Society Meeting, New Orleans, LA, 1/1/2010
• Development of a decision support tool for early differential diagnosis between acute lung injury and cardiogenic pulmonary edema
  K Shahjehan, C Schmickl, G Li, M Malinchoc, O Gajic, American Thoracic Society Meeting, New Orleans, LA, 1/1/2010
• Comparison of serial vital sign measurements around the time of presentation of either Acute Lung Injury or Cardiogenic Pulmonary Edema
  C Schmickl, K Shahjehan, B Pickering, H Kumar, A Ahmed, V Herasevich, P Sharma, R Kashyap, R Cartin-Ceba, O Gajic, Society of Critical Care Medicine conference, Miami, FL, 1/1/2010
• A pilot study examining the effect of ambient intelligence on provider performance, error and omission in a simulated ICU environment
  A Ahmed, H Kumar, R Kashyap, A Alsara, C Schmickl, G Li, V Herasevich, O Gajic, B Pickering, Society of Critical Care Medicine conference, Miami, FL, 1/1/2010
• Clinical-Pathological-Therapeutical Conferences. Can peer-led case-based conferences improve clinical skills?
  D Tauschel, K Büker, C Schmickl, S Balzereit, A Roeder, Association for Medical Education in Europe (AMEE), Malaga, Spain, 1/1/2009
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Other

• Development and Validation of Decision Support Tool for early Differentiation of ALI/ARDS vs Cardiogenic Pulmonary Edema in Critically-ill Patients with Acute Respirat... 
  Schmickl C, Doctoral Thesis
  https://tinyurl.com/CS-Dissertation
  University Witten/Herdecke, Germany
• Online calculator to predict probability of Acute Respiratory Distress Syndrome (ARDS) vs Cardiogenic Pulmonary Edema (CPE) in critically ill patients 
  Schmickl C
  http://icertain.org/alicpe/
• Pneumonia 
  Schmickl C, CERTAIN
  http://www.icertain.org/