ClementeJoseBritto LeonMD

PubMed

• Aberrant immune programming in neutrophils in cystic fibrosis.
  Yawen Hu, Christine M Bojanowski, Clemente J Britto, Dianne Wellems, Kejing Song, Callie Scull, Scott Jennings, Jianxiong Li, Jay K Kolls, Guoshun Wang> ;Journal of Leukocyte Biology. 2024 Feb 23
• Rescue of alveolar wall liquid secretion blocks fatal lung injury due to influenza-staphylococcal coinfection.
  Stephanie Tang, Ana Cassandra De Jesus, Deebly Chavez, Sayahi Suthakaran, Sarah Kl Moore, Keshon Suthakaran, Sonya Homami, Raveen Rathnasinghe, Alison J May, Michael S...> ;The Journal of Clinical Investigation. 2023 Oct 2
• 17 citations
  Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis.
  Hasan H Öz, Ee-Chun Cheng, Caterina Di Pietro, Toma Tebaldi, Giulia Biancon, Caroline Zeiss, Ping-Xia Zhang, Pamela H Huang, Sofia S Esquibies, Clemente J Britto, Jona...> ;Cell Reports. 2022 Dec 13
• 1 citations
  Emerging Approaches to Monitor and Modify Care in the Era of Cystic Fibrosis Transmembrane Conductance Regulators.
  Clemente J Britto, Felix Ratjen, John P Clancy> ;Clinics in Chest Medicine. 2022 Dec 1
• 2 citations
  Cystic Fibrosis in the Era of Highly Effective CFTR Modulators.
  Clemente J Britto, Jennifer L Taylor-Cousar> ;Clinics in Chest Medicine. 2022 Dec 1
• Charting a New Path: A Single-Cell Atlas of Porcine Cystic Fibrosis Airways at Birth.
  Clemente J Britto> ;American Journal of Respiratory Cell and Molecular Biology. 2022 Jun 1
• 16 citations
  SPLUNC1: a novel marker of cystic fibrosis exacerbations.
  Sara Khanal, Megan J. Webster, Naiqian Niu, Jana Zielonka, Myra G. Nunez, Geoffrey Chupp, Martin D. Slade, Lauren Cohn, Maor Sauler, Jose L. Gomez, Robert Tarran, Loke...> ;The European Respiratory Journal. 2021 May 6
• Response.
  Christina C Price, Frederick L Altice, Marwan M Azar, Dayna McManus, Shana E Gleeson, Clemente J Britto, Veronica Azmy, Kelsey Kaman, Matthew Davis, Geoffrey Chupp, Ri...> ;Chest. 2021 May 1
• 7 citations
  Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma.
  Ailu Chen, Maria P Diaz-Soto, Miguel F. Sanmamed, Taylor Adams, Jonas C. Schupp, Amolika Gupta, Clemente J. Britto, Maor Sauler, Xiting Yan, Qing Liu, Gustavo Nino, Ch...> ;Respiratory Research. 2021 Apr 26
• 61 citations
  Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation.
  Kira L. Tomlinson, Tania Wong Fok Lung, Felix Dach, Medini K. Annavajhala, Stanislaw J. Gabryszewski, Ryan A. Groves, Marija Drikic, Nancy Francoeur, Shwetha Hara Srid...> ;Nature Communications. 2021 Mar 3
• 14 citations
  MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease
  Jessica Nouws, Feng Wan, Eric Finnemore, Willy Roque, So-Jin Kim, Isabel S. Bazan, Chuanxing Li, C. Magnus Sköld, Qile Dai, Xiting Yan, Maurizio Chioccioli, Veronique ...> ;JCI Insight. 2021 Jan 25
• 37 citations
  Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis.
  Jonas C. Schupp, Sara Khanal, Jose L. Gomez, Maor Sauler, Taylor Adams, Geoffrey L. Chupp, Xiting Yan, Sergio Poli, Yujiao Zhao, Ruth R. Montgomery, Ivan O. Rosas, Cha...> ;American Journal of Respiratory and Critical Care Medicine. 2020 Nov 13
• 42 citations
  A Network of Sputum MicroRNAs Is Associated with Neutrophilic Airway Inflammation in Asthma
  Jose L. Gomez, Ailu Chen, Maria Paula Diaz, Nicholas Zirn, Amolika Gupta, Clemente J. Britto, Maor Sauler, Xiting Yan, Emma Stewart, Kyle Santerian, Nicole Grant, Qing...> ;American Journal of Respiratory and Critical Care Medicine. 2020 Jul 1
• 146 citations
  Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019: Survival and Clinical Outcomes.
  Christina Price, Frederick L. Altice, Yu Shyr, Alan Koff, Lauren Pischel, George Goshua, Marwan M. Azar, Dayna McManus, Sheau-Chiann Chen, Shana E. Gleeson, Clemente J...> ;Chest. 2020 Jun 15
• 101 citations
  Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation.
  Sebastián A. Riquelme, K. Liimatta, Tania Wong Fok Lung, Blanche L. Fields, Danielle Ahn, David J. Chen, Carmen Lozano, Yolanda Sáenz, Anne-Catrin Uhlemann, Barbara C....> ;Cell Metabolism. 2020 Jun 2
• 15 citations
  Mechanisms of Epithelial Immunity Evasion by Respiratory Bacterial Pathogens
  Lokesh Sharma, Jingjing Feng, Clemente J. Britto, Charles S. Dela Cruz> ;Frontiers in Immunology. 2020 Feb 11
• 12 citations
  Repurposing antimicrobial stewardship tools in the electronic medical record for the management of COVID-19 patients.
  Matthew W. Davis, Dayna McManus, Alan Koff, Gregory R. Jaszczur, Maricar Malinis, Charles S. Dela Cruz, Clemente J. Britto, Christina Price, Veronica Azmy, Kelsey Kama...> ;Infection Control and Hospital Epidemiology. 2020 Jan 1
• 3 citations
  Escalating Mucus Inhibition to the Top of Our Priorities.
  Clemente J. Britto, Lauren Cohn> ;American Journal of Respiratory Cell and Molecular Biology. 2019 Aug 30
• 60 citations
  CFTR-PTEN-dependent mitochondrial metabolic dysfunction promotes Pseudomonas aeruginosa airway infection
  Sebastián A. Riquelme, Carmen Lozano, Ahmed M Moustafa, K. Liimatta, Kira L. Tomlinson, Clemente J. Britto, Sara Khanal, Simren K. Gill, Apurva Narechania, José Manuel...> ;Science Translational Medicine. 2019 Jul 3
• 12 citations
  BPIFA1 regulates lung neutrophil recruitment and interferon signaling during acute inflammation.
  Clemente J. Britto, Naiqian Niu, Sara Khanal, Luai Huleihel, Jose D. Herazo-Maya, Alison Thompson, Maor Sauler, Martin D. Slade, Lokesh Sharma, Charles S. Dela Cruz, N...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2019 Feb 1
• 13 citations
  Regulation and Role of Chitotriosidase during Lung Infection with Klebsiella pneumoniae.
  Lokesh Sharma, Alyssa K. Amick, Swathy Vasudevan, Sei Won Lee, Chad R. Marion, Wei Liu, Virginia Brady, Ashley Losier, Santos Bermejo, Clemente J. Britto, Chun Geun Le...> ;Journal of Immunology. 2018 Jun 11
• 8 citations
  Impaired type I interferon regulation in the blood transcriptome of recurrent asthma exacerbations
  Jose L. Gomez, Maria Paula Diaz, Gustavo Nino, Clemente J. Britto> ;BMC Medical Genomics. 2018 Feb 27
• 2 citations
  A Woman in Her 60s With Lung Adenocarcinoma Presents With Copious Watery Sputum and Respiratory Failure
  Nicole Roeder, Jeffrey D. Marshall, Clemente J. Britto> ;Chest. 2017 Dec 1
• 30 citations
  Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages
  Caterina Di Pietro, Ping-Xia Zhang, Timothy K. O'Rourke, Thomas S. Murray, Lin Wang, Clemente J. Britto, Jonathan L. Koff, Diane S. Krause, Marie E. Egan, Emanuela M. ...> ;Scientific Reports. 2017 Sep 7
• 36 citations
  Cystic Fibrosis Transmembrane Regulator Modulators: Implications for the Management of Depression and Anxiety in Cystic Fibrosis.
  Jaideep S. Talwalkar, Jonathan L. Koff, Hochang B. Lee, Clemente J. Britto, Arielle M. Mulenos, Anna M. Georgiopoulos> ;Psychosomatics. 2017 Jul 1
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