CourtneyWHouchenMD

PubMed

• 3 citations
  Lysosomes Promote Cancer Metastasis via Exosome in PTEN-Deficient Tumors.
  Zhijun Zhou, Morgan M Bonds, Barish H Edil, Courtney W Houchen, Zhihua Liu, Min Li> ;Gastroenterology. 2023 Mar 1
• Replication stress identifies novel molecular classification associated with treatment outcomes in pancreatic cancer.
  Zhijun Zhou, Anuj K Saluja, Courtney W Houchen, Min Li> ;Pancreatology. 2023 Jan 1
• 3 citations
  Targeting Doublecortin-Like Kinase 1 (DCLK1)-Regulated SARS-CoV-2 Pathogenesis in COVID-19.
  Ram Babu Undi, Jason L Larabee, Adrian Filiberti, Susanna Ulahannan, Sheeja Aravindan, Edana Stroberg, Lisa M Barton, Eric J Duval, Sanjay Mukhopadhyay, James C Hentho...> ;Journal of Virology. 2022 Sep 14
• 10 citations
  Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
  Zhijun Zhou, Yu Ren, Jingxuan Yang, Mingyang Liu, Xiuhui Shi, Wenyi Luo, Kar-Ming Fung, Chao Xu, Michael S Bronze, Yuqing Zhang, Courtney W Houchen, Min Li> ;Gastroenterology. 2022 Nov 1
• 39 citations
  Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-β Signaling Axis in Pancreatic Cancer.
  Xiuhui Shi, Jingxuan Yang, Mingyang Liu, Yuqing Zhang, Zhijun Zhou, Wenyi Luo, Kar-Ming Fung, Chao Xu, Michael S Bronze, Courtney W Houchen, Min Li> ;Gastroenterology. 2022 Jun 1
• 1 citations
  Patient-Derived Organoid Pharmacotyping Guides Precision Medicine for Pancreatic Cancer.
  Yuqing Zhang, Courtney W Houchen, Min Li> ;Clinical Cancer Research. 2022 Aug 2
• 3 citations
  A Novel Translational Activation of HIF1α Promotes Pancreatic Cancer Growth Through Glycolytic Reprogramming.
  Yuqing Zhang, Courtney W Houchen, Min Li> ;Gastroenterology. 2022 Apr 1
• 3 citations
  Attenuating DNA damage response and immunosuppression radiosensitizes pancreatic cancer.
  Yuqing Zhang, Courtney W Houchen, Min Li> ;Ebiomedicine. 2022 Feb 1
• 7 citations
  Reg4 interacts with CD44 to regulate proliferation and stemness of colorectal and pancreatic cancer cells.
  Kumar S. Bishnupuri, Satheesh K. Sainathan, Matthew A. Ciorba, Courtney W. Houchen, Brian K. Dieckgraefe> ;Molecular Cancer Research. 2021 Nov 9
• 9 citations
  Inflammatory Mediators and Gut Microbial Toxins Drive Colon Tumorigenesis by IL-23 Dependent Mechanism.
  Janani Panneerselvam, Venkateshwar Madka, Rajani Rai, Katherine T. Morris, Courtney W. Houchen, Parthasarathy Chandrakesan, Chinthalapally V. Rao> ;Cancers. 2021 Oct 14
• 1 citations
  Interplay of Tumor Microenvironment Factors and Cancer Stem Cell Enrichment in Pancreatic Ductal Adenocarcinoma.
  Yuqing Zhang, Jingxuan Yang, Michael S. Bronze, Courtney W. Houchen, Min Li> ;Gastroenterology. 2021 Sep 14
• 33 citations
  An integrated model of N6-methyladenosine regulators to predict tumor aggressiveness and immune evasion in pancreatic cancer.
  Zhijun Zhou, Junxia Zhang, Chao Xu, Jingxuan Yang, Yuqing Zhang, Mingyang Liu, Xiuhui Shi, Xiaoping Li, Hanxiang Zhan, Wei Chen, Lacey R. McNally, Kar Ming Fung, Wenyi...> ;Ebiomedicine. 2021 Mar 1
• 76 citations
  Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer
  Mingyang Liu, Yuqing Zhang, Jingxuan Yang, Hanxiang Zhan, Zhijun Zhou, Yuanyuan Jiang, Xiuhui Shi, Xiao Fan, Junxia Zhang, Wenyi Luo, Kar Ming Fung, Chao Xu, Michael S...> ;Gastroenterology. 2021 Apr 1
• 3 citations
  Discovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases.
  Nagendra Sastri Yarla, Gopal Pathuri, Hariprasad Gali, Simon Terzyan, Janani Panneerselvam, Parthasarathy Chandrakesan, Marcus Tullius Scotti, Courtney W. Houchen, Ven...> ;Journal of Inflammation Research. 2020 Dec 31
• 24 citations
  Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment.
  Zhiyun Cao, Nathaniel Weygant, Parthasarathy Chandrakesan, Courtney W. Houchen, Jun Peng, Dongfeng Qu> ;Cancers. 2020 Dec 17
• 96 citations
  Proximal colon–derived O-glycosylated mucus encapsulates and modulates the microbiota
  Kirk Bergstrom, Xindi Shan, David Casero, Albert Batushansky, Venu Lagishetty, Jonathan P. Jacobs, Christopher M. Hoover, Yuji Kondo, Bojing Shao, Liang Gao, Wesley F....> ;Science. 2020 Oct 23
• 2 citations
  Tuft Cells Play Critical Roles in the Heterogeneity and Epithelial Plasticity in Pancreatic Cancer Initiation and Progression.
  Landon L. Moore, Zhijun Zhou, Min Li, Courtney W. Houchen> ;Gastroenterology. 2020 Sep 9
• 1 citations
  A subset of epithelial cells mimics regulatory T cells and contributes to immune evasion during development of pancreatic adenocarcinoma
  Courtney W. Houchen, Min Li> ;BMC Medicine. 2020 Jun 29
• 6 citations
  Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical β-catenin-dependent mechanism.
  Naushad Ali, Charles B. Nguyen, Parthasarathy Chandrakesan, Roman F. Wolf, Dongfeng Qu, Randal May, Tatiana Goretsky, Javid Fazili, Terrence A. Barrett, Min Li, Mark M...> ;Scientific Reports. 2020 Jun 29
• 27 citations
  DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4.
  Janani Panneerselvam, Priyanga Mohandoss, Ravi Patel, Hamza Gillan, Michael Li, Kirtana Kumar, DangHuy Nguyen, Nathaniel Weygant, Dongfeng Qu, Kamille Pitts, Stanley L...> ;Molecular Therapy Oncolytics. 2020 May 27
• 19 citations
  DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization.
  Parthasarathy Chandrakesan, Janani Panneerselvam, Randal May, Nathaniel Weygant, Dongfeng Qu, William R. Berry, Kamillee Pitts, Ben Z. Stanger, Chinthalapally V. Rao, ...> ;Molecular Cancer Therapeutics. 2020 Jul 1
• 68 citations
  ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Canc...
  Mingyang Liu, Yuqing Zhang, Jingxuan Yang, Xiaobo Cui, Zhijun Zhou, Hanxiang Zhan, Kai Ding, Xiang Tian, Zhibo Yang, Kar Ming A. Fung, Barish H. Edil, Russell G. Posti...> ;Gastroenterology. 2020 Feb 1
• 50 citations
  Cancer Stem Cell Marker DCLK1 Correlates with Tumorigenic Immune Infiltrates in the Colon and Gastric Adenocarcinoma Microenvironments.
  Xiangyan Wu, Dongfeng Qu, Nathaniel Weygant, Jun Peng, Courtney W. Houchen> ;Cancers. 2020 Jan 22
• 33 citations
  DCLK1 Monoclonal Antibody-Based CAR-T Cells as a Novel Treatment Strategy against Human Colorectal Cancers.
  Sripathi M. Sureban, Robert Berahovich, Hua Zhou, Shirley Xu, Lijun Wu, Kai Ding, Randal May, Dongfeng Qu, Edwin Bannerman-Menson, Vita M. Golubovskaya, Courtney W. Ho...> ;Cancers. 2019 Dec 23
• 47 citations
  Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis.
  Jun Yi, Kirk Bergstrom, Jianxin Fu, Xindi Shan, J. Michael McDaniel, Samuel McGee, Dongfeng Qu, Courtney W. Houchen, Xiaowei Liu, Lijun Xia> ;Cell Death and Differentiation. 2019 Sep 1
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