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Office
401 E Chestnut St
Suite 310
Louisville, KY 40202Phone+1 502-584-8563Fax+1 502-562-6196- Is this information wrong?
Education & Training
- University of MinnesotaFellowship, Gastroenterology, 1975 - 1977
- UPMC Medical EducationResidency, Internal Medicine, 1972 - 1975
- University of Tennessee Health Science Center College of MedicineClass of 1972
- Earlham CollegeBA, 1968
Certifications & Licensure
- KY State Medical License 1982 - 2025
- OH State Medical License 2005 - 2006
- MN State Medical License 1976 - 1982
- PA State Medical License 1973 - 1976
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- Fellow American Association for the Study of Liver Diseases, 2014
- NIH Mark Keller Honorary Lecture honoree NIH, 2014
- Distinguished Faculty Award in Research for Basic and Applied Sciences UofL, 2013
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Clinical Trials
- Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis Start of enrollment: 2013 Sep 01
- Novel Therapies in Moderately Severe Acute Alcoholic Hepatitis Start of enrollment: 2013 Aug 01
- Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis Start of enrollment: 2020 Jul 10
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Publications & Presentations
PubMed
- Steroid responsiveness in alcohol-associated hepatitis is linked to glucocorticoid metabolism, mitochondrial repair, and heat shock proteins.Josiah Hardesty, Meghan Hawthorne, Le Day, Jeffrey Warner, Dennis Warner, Marina Gritsenko, Aliya Asghar, Andrew Stolz, Timothy Morgan, Craig McClain, Jon Jacobs, Irin...> ;Hepatology Communications. 2024 Mar 1
- 1 citationsRandomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis.Samer Gawrieh, Srinivasan Dasarathy, Wanzhu Tu, Patrick S Kamath, Naga P Chalasani, Craig J McClain, Ramon Bataller, Gyongyi Szabo, Qing Tang, Svetlana Radaeva, Bruce ...> ;Journal of Hepatology. 2024 Feb 10
- ALT poorly predicts Nonalcoholic Fatty Liver Disease (NAFLD) and liver fibrosis as determined by vibration-controlled transient elastography in adult National Health a...Sally Condon, Huirong Hu, Maiying Kong, Matthew C Cave, Craig J McClain> ;The American Journal of the Medical Sciences. 2024 May 1
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Journal Articles
- Copper-Fructose Interactions: A Novel Mechanism in the Pathogenesis of NAFLDMiriam B Vos, Craig J McClain, MDPI
- Nutrition in Patients with CirrhosisCraig McClain, MD, National Institutes of Health
- Simultaneous Quantification of Straight-Chain and Branched-Chain Short Chain Fatty Acids by Gas Chromatography Mass SpectrometryCraig McClain, Craig McClain, ScienceDirect
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Books/Book Chapters
Abstracts/Posters
- Special Topic Issue: Liver and Pancreatic Diseases: Consequences of Chronic Alcoholic ConsumptionSinger MV, Dooley S, McClain CJ, Zakhari S, Dig Dis, Falk Workshop, Freiburg, 1/1/2010
- National Consensus Counsel on OTC AnalgesicsMcClain CJ, Ft. Lauderdale, Florida, 1/1/1993
- International Cytokine Research ConferenceMcClain CJ, Hilton Head, SC, 1/1/1987
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Lectures
- CAM and GI DiseaseChicago, Illinois - 1/1/2001
- Nutrition Support and Liver Disease: Traditional and Nontraditional ApproachesLouisville, Kentucky - 1/1/2001
- Monocytes and ALDMontreal, Canada - 1/1/2001
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Other
- Liver TransplantationFrimodig, J
1/1/2015 - Liver, Environmental Toxins and EpigeneticsGhare, S
1/1/2015 - Acrolein in ALDChen, J
1/1/2015 - Join now to see all
Press Mentions
- UofL and Robley Rex VA Medical Center Partnership Leads to New State-of-the-Art Multiphoton Microscopes for Exposure StudiesNovember 22nd, 2022
- UofL Receives $11.3 Million Grant for Liver Research CenterJune 21st, 2021
- University of Louisville Receives NIH Funding to Support Research into Liver-Related IllnessJune 21st, 2021
Grant Support
- Alcohol, Proteasome Dysfunction In Liver InjuryVeterans Affairs2011–2012
- Summer Environmental Health Sciences Training ProgramNational Institute Of Environmental Health Sciences2011–2012
- Cyclic AMP, Cytokine Modulation And Alcoholic Liver DiseaseNational Institute On Alcohol Abuse And Alcoholism2009–2011
- The Role Of Alcohol In HIV Therapy HepatotoxicityNational Institute On Alcohol Abuse And Alcoholism2008–2011
- University Of Louisville Bioinformatics Faculty Recruitment For EpigeneticsNational Institute On Alcohol Abuse And Alcoholism2009–2010
- Biomarkers For SteatohepatitisNational Institute On Alcohol Abuse And Alcoholism2009–2010
- Alcohol Liver Disease And Alcohol-Nutrient InteractionsNational Institute On Alcohol Abuse And Alcoholism2008–2010
- Administrative CoreNational Institute On Alcohol Abuse And Alcoholism2008–2010
- TNF And Mitochondrial Dysfunction In ALDNational Institute On Alcohol Abuse And Alcoholism2006–2010
- S-Adenosylhomocysteine And S-Adenosylmethionine In Alcoholic Liver DiseaseNational Institute On Alcohol Abuse And Alcoholism2005–2010
- Mechanisms Of S-Adenosylmethionine In NASHNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2009
- Planning Grant For Louisville Clinical And Translational Science AwardNational Center For Research Resources2006
- Tumor Necrosis Factor And Alcoholic Liver DiseaseNational Institute On Alcohol Abuse And Alcoholism2001–2005
- Alcohol Liver Disease And S-AdenosylmethionineNational Institute On Alcohol Abuse And Alcoholism2001–2005
- A.S.P.E.N. Research Workshop On Functional FoodsNational Institute Of Diabetes And Digestive And Kidney Diseases2002
- Alcohol, Nutrition, And ImmunomodulationNational Institute On Alcohol Abuse And Alcoholism2000
- Alcohol, Nutrition, And ImmunomodulationNational Institute On Alcohol Abuse And Alcoholism1996–2000
- Pharmacokinetics And Pharmacodynamics Of Procysteine In Liver DiseaseNational Center For Research Resources1997–1999
- Alcohol Liver Disease And S AdenosylmethionineNational Institute On Alcohol Abuse And Alcoholism1998
- Altered Hepatic Metabolism Following Head InjuryNational Institute Of Neurological Disorders And Stroke1996–1998
Professional Memberships
- Fellow
Hospital Affiliations
- UofL Health - Jewish HospitalLouisville, Kentucky
- Norton Audubon HospitalLouisville, Kentucky
- Norton HospitalLouisville, Kentucky
- UofL Health - UofL HospitalLouisville, Kentucky
- Robley Rex Department of Veterans Affairs Medical CenterLouisville, Kentucky
- Norton Children's HospitalLouisville, Kentucky
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