DanielLBakerMD

PubMed

• Autotaxin inhibition: Development and application of computational tools to identify site-selective lead compounds.
  Norman, D. D.,Ibezim, A.,Scott, W. E.,White, S.,Parrill, A. L.,Baker, D. L.> ;Bioorg. Med. Chem.. 2013 Sep 1
• 28 citations
  Hits of a high-throughput screen identify the hydrophobic pocket of autotaxin/lysophospholipase D as an inhibitory surface.
  James I. Fells, Sue Chin Lee, Yuko Fujiwara, Derek D. Norman, Keng Gat Lim, Ryoko Tsukahara, Jianxiong Liu, Renukadevi Patil, Duane D. Miller, R. Jason Kirby, Sandra N...> ;Molecular Pharmacology. 2013 Sep 1
• Gold Nanorods Carrying Paclitaxel for Photothermal-Chemotherapy of Cancer.
  Ren, F.,Bhana, S.,Norman, D. D.,Johnson, J.,Xu, L.,Baker, D. L.,Parrill, A. L.,Huang, X.> ;Bioconjug Chem. 2013 Mar 20
• Structure and catalytic function of sphingosine kinases: Analysis by site-directed mutagenesis and enzyme kinetics.
  Baker, D. L.,Pham, T. C.,Sparks, M. A.> ;Biochim Biophys Acta. 2013 Jan
• Computational Identification and Experimental Characterization of Substrate Binding Determinants of Nucleotide Pyrophosphatase/Phosphodiesterase 7.
  Parrill, A.L., Wanjala, I.W., Pham, T.T., Baker, D.L.> ;BMC Biochem. 2011
• Ligand-based autotaxin pharmacophore models reflect structure-based docking results.
  Mize, C.D., Abbott, A.M., Gacasan, S.B., Parrill, A.L., Baker, D.L.> ;J Mol Graph Model. 2011 Nov
• The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation.
  Bolen, A.L., Naren, A.P., Yarlagadda, S., Beranova-Giorgianni, S., Chen, L., Norman, D., Baker, D.L., Rowland, M.M., Best, M.D., Sano, T., Tsukahara, T., Liliom, K., I...> ;J Lipid Res. 2011 May
• 45 citations
  Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity
  Renuka Gupte, Renukadevi Patil, Jianxiong Liu, Yaohong Wang, Sue C. Lee, Yuko Fujiwara, James I. Fells, Alyssa L. Bolen, Karin Emmons-Thompson, C. Ryan Yates, Anjaih S...> ;ChemMedChem. 2011 May 2
• 15 citations
  Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid
  Renuka Gupte, Anjaih Siddam, Yan Lu, Wei Li, Yuko Fujiwara, Nattapon Panupinthu, Truc Chi T. Pham, Daniel L. Baker, Abby L. Parrill, Mari Gotoh, Kimiko Murakami-Murofu...> ;Bioorganic & Medicinal Chemistry Letters. 2010 Dec 15
• Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid.
  Tsukahara, T., Tsukahara, R., Fujiwara, Y., Yue, J., Cheng, Y., Guo, H., Bolen, A., Zhang, C., Balazs, L., Re, F., Du, G., Frohman, M.A., Baker, D.L., Parrill, A.L., U...> ;Mol Cell. 2010 Aug 13
• Pharmacophore development and application toward the identification of novel, small-molecule autotaxin inhibitors.
  North, E.J., Howard, A.L., Wanjala, I.W., Pham, T.T., Baker, D.L., Parrill, A.L.> ;J Med Chem. 2010 Apr 22
• Optimization of a pipemidic acid autotaxin inhibitor.
  Hoeglund, A.B., Bostic, H.E., Howard, A.L., Wanjala, I.W., Best, M.D., Baker, D.L., Parrill, A.L.> ;J Med Chem. 2010 Feb 11
• Determination of protein-RNA interaction sites in the Cbf5-H/ACA guide RNA complex by mass spectrometric protein footprinting.
  Baker, D.L., Seyfried, N.T., Li, H., Orlando, R., Terns, R.M., Terns, M.P.> ;Biochemistry. 2008 Feb 12
• 127 citations
  Carba Analogs of Cyclic Phosphatidic Acid Are Selective Inhibitors of Autotaxin and Cancer Cell Invasion and Metastasis
  Daniel L. Baker, Yuko Fujiwara, Kathryn R. Pigg, Ryoko Tsukahara, Susumu Kobayashi, Hiromu Murofushi, Ayako Uchiyama, Kimiko Murakami-Murofushi, Eunjin Koh, Russell W....> ;Journal of Biological Chemistry. 2006 Aug 11
• Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor g...
  Tsukahara, T., Tsukahara, R., Yasuda, S., Makarova, N., Valentine, W.J., Allison, P., Yuan, H., Baker, D.L., Li, Z., Bittman, R., Parrill, A., Tigyi, G.> ;J Biol Chem. 2006 Feb 10
• Synthesis of photoactivatable analogues of lysophosphatidic acid and covalent labeling of plasma proteins.
  Li, Z., Baker, D.L., Tigyi, G., Bittman, R.> ;J Org Chem. 2006 Jan 20
• RNA-guided RNA modification: functional organization of the archaeal H/ACA RNP.
  Baker, D. L.,Youssef, O. A.,Chastkofsky, M. I.,Dy, D. A.,Terns, R. M.,Terns, M. P.> ;Genes Dev. 2005 May 15
• 161 citations
  Lysophosphatidic Acid Induces Neointima Formation Through PPARγ Activation
  Chunxiang Zhang, Daniel L. Baker, Satoshi Yasuda, Natalia Makarova, Louisa Balazs, Leonard R. Johnson, Gopal K. Marathe, Thomas M. McIntyre, Yong Xu, Glenn D. Prestwic...> ;Journal of Experimental Medicine. 2004 Mar 15
• Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques.
  Rother, E., Brandl, R., Baker, D.L., Goyal, P., Gebhard, H., Tigyi, G., Siess, W.> ;Circulation. 2003 Aug 12
• Plasma lysophosphatidic acid concentration and ovarian cancer.
  Baker, D.L., Morrison, P., Miller, B., Riely, C.A., Tolley, B., Westermann, A.M., Bonfrer, J.G., Bais, E., Moolenaar, W.H., Tigyi, G.> ;JAMA. 2002 Jun 19
• Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level.
  Yue, J., Yokoyama, K., Balazs, L., Baker, D. L., Smalley, D., Pilquil, C., Brindley, D. N., Tigyi, G.> ;Cell Signal. 2004 Mar
• Autotaxin inhibition: challenges and progress toward novel anti-cancer agents.
  Parrill, A. L., Baker, D. L.> ;Anticancer Agents Med Chem. 2008 Dec 01
• (S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin ac...
  Valentine, W. J., Kiss, G. N., Liu, J., E, S., Gotoh, M., Murakami-Murofushi, K., Pham, T. C., Baker, D. L., Parrill, A. L., Lu, X., Sun, C., Bittman, R., Pyne, N. J.,...> ;Cell Signal. 2010 Oct
• Molecular basis for lysophosphatidic acid receptor antagonist selectivity.
  Sardar, V. M., Bautista, D. L., Fischer, D. J., Yokoyama, K., Nusser, N., Virag, T., Wang, D. A., Baker, D. L., Tigyi, G., Parrill, A. L.> ;Biochim Biophys Acta. 2002 May 23
• Stereochemical properties of lysophosphatidic acid receptor activation and metabolism.
  Yokoyama, K., Baker, D. L., Virag, T., Liliom, K., Byun, H. S., Tigyi, G., Bittman, R.> ;Biochim Biophys Acta. 2002 May 23
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