DanielBRosenbluthMD

Pulmonology • Saint Louis, MO

Critical Care Medicine, Cystic Fibrosis, Interventional Pulmonology, Pleural Disease

Tracey C. and William J. Marshall Professor of Medicine, Washington University School of Medicine, St Louis, MO

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Office
1 Barnes Jewish Hospital Plz
Saint Louis, MO 63110
Phone+1 314-362-7578

Fax+1 314-286-1021
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Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Pulmonary Disease and Critical Care Medicine, 1992 - 1995
McGaw Medical Center of Northwestern UniversityResidency, Internal Medicine, 1989 - 1992
Icahn School of Medicine at Mount SinaiClass of 1989

Certifications & Licensure

IL State Medical License 1991 - 2026
MO State Medical License 1994 - 2025
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2010-2014
CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012

Clinical Trials

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion Start of enrollment: 2014 Mar 01
Completed
Phase 2
Study of Ataluren in Nonsense Mutation Cystic Fibrosis (ACT CF) Start of enrollment: 2014 Aug 01
Completed
Phase 3
Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation Start of enrollment: 2015 Nov 01
Completed
Phase 2
Study of Cavosonstat (N91115) in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor Start of enrollment: 2016 Apr 01
Unknown status
Phase 2
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Publications & Presentations

PubMed

3 citations
Riociguat for the treatment of Phe508del homozygous adults with cystic fibrosis.
Nico Derichs, Jennifer L. Taylor-Cousar, Jane C. Davies, Isabelle Fajac, Elizabeth Tullis, Dilip Nazareth, Damian G. Downey, Daniel B. Rosenbluth, Anne Malfroot, Clare...> ;Journal of Cystic Fibrosis. 2021 Aug 19
31 citations
Evaluating the Impact of Stopping Chronic Therapies after Modulator Drug Therapy in Cystic Fibrosis: The SIMPLIFY Clinical Trial Study Design.
Nicole Mayer-Hamblett, David P. Nichols, Katherine Odem-Davis, Kristin A. Riekert, Greg S. Sawicki, Scott H. Donaldson, Felix Ratjen, Michael W. Konstan, Noah Simon, D...> ;Annals of the American Thoracic Society. 2021 Jul 30
10 citations
The impact of SARS-CoV-2 on the cystic fibrosis foundation therapeutics development network.
K. Pearson, Nicole Mayer-Hamblett, Christopher H. Goss, George Z. Retsch-Bogart, Jill M. VanDalfsen, Patricia Burks, Daniel B. Rosenbluth, John P. Clancy, Amy Hoffman,...> ;Journal of Cystic Fibrosis. 2021 Mar 1
24 citations
Long-term safety and efficacy of tezacaftor–ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR ...
Patrick A. Flume, Reta Fischer Biner, Damian G Downey, Cynthia A. Brown, Manu Jain, Rainald Fischer, Kris De Boeck, Gregory S Sawicki, Philip Chang, Hildegarde Paz-Dia...> ;The Lancet. Respiratory Medicine. 2021 Feb 10
5 citations
Multi-dimensional clinical phenotyping of a national cohort of adult cystic fibrosis patients
Douglas Conrad, Joanne Billings, Charlotte C. Teneback, Jonathan L. Koff, Daniel B. Rosenbluth, Barbara A. Bailey, Raksha Jain> ;Journal of Cystic Fibrosis. 2021 Jan 1
115 citations
Lung transplant referral for individuals with cystic fibrosis: Cystic Fibrosis Foundation consensus guidelines
Kathleen J. Ramos, Patrick Smith, Edward F. McKone, Joseph M. Pilewski, Amy Lucy, Sarah E. Hempstead, E. Tallarico, Albert Faro, Daniel B. Rosenbluth, Alice L. Gray, J...> ;Journal of Cystic Fibrosis. 2019 May 1
39 citations
Forced Expiratory Volume in 1 Second Variability Helps Identify Patients with Cystic Fibrosis at Risk of Greater Loss of Lung Function
Wayne J. Morgan, Donald R. VanDevanter, David J. Pasta, Aimee J. Foreman, Jeffrey S. Wagener, Michael W. Konstan, Ted Liou, Susanna A. McColley, Ann McMullen, Alexandr...> ;The Journal of Pediatrics. 2016 Feb 1
Cavitary lung nodules in a patient with prior squamous cell carcinoma of the submandibular gland.
Hrishikesh S. Kulkarni, Daniel B. Rosenbluth> ;American Journal of Respiratory and Critical Care Medicine. 2014 Dec 15
121 citations
Gender Differences in Outcomes of Patients with Cystic Fibrosis
Cayce L. Harness-Brumley, Alan C. Elliott, Daniel B. Rosenbluth, Deepa Raghavan, Raksha Jain> ;Journal of Women's Health. 2014 Dec 1
250 citations
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial
Eitan Kerem, Michael W. Konstan, Kris De Boeck, Frank J. Accurso, Isabelle Sermet-Gaudelus, Michael Wilschanski, J. Stuart Elborn, Paola Melotti, Inez Bronsveld, Isabe...> ;The Lancet. Respiratory Medicine. 2014 Jul 1
36 citations
Effects of puberty on cystic fibrosis related pulmonary exacerbations in women versus men
Shelby Sutton, Daniel B. Rosenbluth, Deepa Raghavan, Jie Zheng, Raksha Jain> ;Pediatric Pulmonology. 2014 Jan 1
409 citations
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation
John P. Clancy, Steven M. Rowe, Frank J. Accurso, Moira L. Aitken, Raouf S. Amin, Melissa A. Ashlock, Manfred Ballmann, Michael P. Boyle, Inez Bronsveld, Preston W. Ca...> ;Thorax. 2012 Jan 1
21 citations
A Randomized Trial of Conventional Chest Physical Therapy Versus High Frequency Chest Wall Compressions in Intubated and Non-intubated Adults
Darnetta Clinkscale, Kathleen Spihlman, Peggy Watts, Daniel B. Rosenbluth, Marin H. Kollef> ;Respiratory Care. 2011 Jan 1
61 citations
Randomized trial of biofilm testing to select antibiotics for cystic fibrosis airway infection.
Samuel M. Moskowitz, Julia Emerson, Sharon McNamara, Richard Shell, David M. Orenstein, Daniel B. Rosenbluth, Marcia Katz, Richard C. Ahrens, Douglas B. Hornick, Patri...> ;Pediatric Pulmonology. 2011 Feb 1
44 citations
[18F]fluorodeoxyglucose positron emission tomography for lung antiinflammatory response evaluation.
Delphine L. Chen, Timothy J. Bedient, James Kozlowski, Daniel B. Rosenbluth, Warren Isakow, Thomas W. Ferkol, Betsy Thomas, Mark A. Mintun, Daniel P. Schuster, Michael...> ;American Journal of Respiratory and Critical Care Medicine. 2009 Sep 15
33 citations
Barriers to adherence to cystic fibrosis infection control guidelines
Elizabeth Garber, Manisha Desai, Juyan Zhou, Luis Alba, Denise B. Angst, Michael D. Cabana, Lisa Saiman, Robert Kaslovsky, Scott A. Schroeder, Raj Padman, Amy Szymansk...> ;Pediatric Pulmonology. 2008 Sep 1
4 citations
Upregulation of elastin expression in constrictive bronchiolitis obliterans.
Adrian Shifren, Jason C. Woods, Daniel B. Rosenbluth, Susan Officer, Joel D. Cooper, Richard A. Pierce> ;International Journal of Chronic Obstructive Pulmonary Disease. 2007 Jan 1
75 citations
Quantifying Pulmonary Inflammation in Cystic Fibrosis with Positron Emission Tomography
Delphine L. Chen, Thomas W. Ferkol, Mark A. Mintun, Jessica E. Pittman, Daniel B. Rosenbluth, Daniel P. Schuster> ;American Journal of Respiratory and Critical Care Medicine. 2006 Jun 15
70 citations
FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin.
Delphine L. Chen, Daniel B. Rosenbluth, Mark A. Mintun, Daniel P. Schuster> ;Journal of Applied Physiology. 2006 May 1
37 citations
Chronic Colonization with Pandoraea apista in Cystic Fibrosis Patients Determined by Repetitive-Element-Sequence PCR
R. M. Atkinson, John J. LiPuma, Daniel B. Rosenbluth, W. M. Dunne> ;Journal of Clinical Microbiology. 2006 Mar 1
105 citations
Lung function decline in cystic fibrosis patients and timing for lung transplantation referral.
Daniel B. Rosenbluth, Kevin F. Wilson, Thomas W. Ferkol, Daniel P. Schuster> ;Chest. 2004 Aug 1
13 citations
Pulmonary hyalinizing granuloma associated with Aspergillus infection.
J. Keith Pinckard, Daniel B. Rosenbluth, Kishor Patel, Louis P. Dehner, John D. Pfeifer> ;International Journal of Surgical Pathology. 2003 Jan 1
11 citations
Cystic Fibrosis in an Elderly Woman
Daniel B. Rosenbluth, Daniel M. Goodenberger> ;Chest. 1997 Oct 1
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Press Mentions

List of Temporary Practice Permits Granted May 5, 2020May 5th, 2020
New Drug Appears to Slow Effects of Cystic Fibrosis, Offering Hope to Long-Suffering PatientsDecember 18th, 2019