MuraliMChakinalaMD

Pulmonology • Saint Louis, MO

Critical Care Medicine, Pulmonary Vascular Medicine

Associate Professor, Internal Medicine, Washington University School of Medicine

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Office
4921 Parkview Pl
Fl 8
Saint Louis, MO 63110
Phone+1 314-454-8917

Fax+1 314-454-5571
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Summary

Dr. Murali Chakinala is a pulmonologist in Saint Louis, MO and is affiliated with multiple hospitals in the area, including Barnes-Jewish Hospital and Barnes-Jewish West County Hospital. He received his medical degree from Vanderbilt University School of Medicine and has been in practice 23 years. He specializes in pulmonary vascular diseases, thromboembolic disease and general pulmonology.

Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Pulmonary Disease and Critical Care Medicine, 1999 - 2002
University of Texas Southwestern Medical CenterResidency, Internal Medicine, 1994 - 1998
Vanderbilt University School of MedicineClass of 1994

Certifications & Licensure

IL State Medical License 2022 - 2026
MO State Medical License 2000 - 2025
TX State Medical License 1996 - 1999
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Best Doctors in America 2011-2019
Outstanding Physician of the Year Pulmonary Hypertension Association, 2014

Clinical Trials

Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia Start of enrollment: 2010 Apr 08
Recruiting
Study in Subjects With PAH and PH Secondary to IPF Using Inhaled GeNOsyl. Start of enrollment: 2011 Mar 01
Completed
Phase 2
North American Study of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) Start of enrollment: 2011 Aug 01
Completed
Phase 2
Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument Start of enrollment: 2013 Apr 01
Completed
Phase 3
Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT Start of enrollment: 2014 May 31
Completed
Phase 2
Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER Start of enrollment: 2017 Apr 18
Terminated
Phase 3
Pulmonary Hypertension Association Registry Start of enrollment: 2015 Oct 01
Recruiting
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

IMPAHCT: A randomized phase 2b/3 study of inhaled imatinib for pulmonary arterial hypertension.
Hunter Gillies, Benjamin T Dake, Jeremy P Feldman, Marius M Hoeper, Marc Humbert, Zhi-Cheng Jing, Jonathan Langley, Ralph W Niven, Stephan Rosenkranz, Xiaosha Zhang, M...> ;Pulmonary Circulation. 2024 Jan 1
1 citations
Disease characteristics, treatments, and outcomes of patients with pulmonary arterial hypertension treated with selexipag in real-world settings from the SPHERE regist...
Vallerie McLaughlin, Harrison W Farber, Kristin B Highland, Anna R Hemnes, Murali M Chakinala, Kelly M Chin, Michelle Han, Michelle Cho, Tobore Tobore, Mohammad Rahman...> ;The Journal of Heart and Lung Transplantation. 2024 Feb 1
Characteristics of patients with pulmonary arterial hypertension from an innovative, comprehensive real-world patient data repository.
Harrison W Farber, Murali M Chakinala, Michelle Cho, Robert P Frantz, Andrew Frick, Lisa Lancaster, Scott Milligan, Ronald Oudiz, Sumeet Panjabi, Yuen Tsang, Steven D ...> ;Pulmonary Circulation. 2023 Jul 1
Impact of the COVID-19 pandemic on chronic disease management and patient reported outcomes in patients with pulmonary hypertension: The Pulmonary Hypertension Associa...
Mayer, M., Badesch, D., Nielsen, K., Kawut, S., Bull, T., Ryan, J., Sager, J., Mazimba, S., Hemnes, A., Klinger, J., Runo, J., McConnell, J., De Marco, T., Chakinala, ...> ;Pulmonary Circulation. 2023 Apr 1
6 citations
AV-101, a novel inhaled dry-powder formulation of imatinib, in healthy adult participants: a phase 1 single and multiple ascending dose study.
Hunter Gillies, Ralph Niven, Benjamin T Dake, Murali M Chakinala, Jeremy P Feldman, Nicholas S Hill, Marius M Hoeper, Marc Humbert, Vallerie V McLaughlin, Martin Kankam> ;ERJ Open Research. 2023 Mar 1
2 citations
Anticoagulation in pulmonary arterial hypertension - association with mortality, healthcare utilization, and quality of life: The Pulmonary Hypertension Association Re...
Jonah D Garry, Nicholas A Kolaitis, Richard Kronmal, Thenappan Thenappan, Anna Hemnes, Daniel Grinnan, Todd Bull, Murali M Chakinala, Evelyn Horn, Marc A Simon, Teresa...> ;The Journal of Heart and Lung Transplantation. 2022 Dec 1
3 citations
Palliative care referrals in patients with pulmonary arterial hypertension: The Pulmonary Hypertension Association Registry.
Anne B Rohlfing, Kara E Bischoff, Nicholas A Kolaitis, Richard A Kronmal, Noah A Kime, Michael P Gray, Sonja Bartolome, Murali M Chakinala, Robert P Frantz, Corey E Ve...> ;Respiratory Medicine. 2023 Jan 1
Erratum: Health disparities and treatment approaches in portopulmonary hypertension and idiopathic pulmonary arterial hypertension: An analysis of the Pulmonary Hypert...
Hilary M DuBrock, Charles D Burger, Sonja D Bartolome, Jeremy P Feldman, David D Ivy, Erika B Rosenzweig, Jeffrey S Sager, Kenneth W Presberg, Stephen C Mathai, Matthe...> ;Pulmonary Circulation. 2022 Oct 1
3 citations
Prediction of patient outcomes through social determinants of health: The Pulmonary Hypertension Association Registry (PHAR) evaluation.
Dan Grinnan, Le Kang, Christine DeWilde, David Badesch, Raymond Benza, Todd Bull, Murali Chakinala, Teresa DeMarco, Jeremy Feldman, Hubert J Ford, James Klinger, John ...> ;Pulmonary Circulation. 2022 Jul 1
47 citations
Mortality in Pulmonary Arterial Hypertension in the Modern Era: Early Insights From the Pulmonary Hypertension Association Registry.
Kevin Y Chang, Sue Duval, David B Badesch, Todd M Bull, Murali M Chakinala, Teresa De Marco, Robert P Frantz, Anna Hemnes, Stephen C Mathai, Erika Berman Rosenzweig, J...> ;Journal of the American Heart Association. 2022 May 3
4 citations
Delphi consensus recommendation for optimization of pulmonary hypertension therapy focusing on switching from a phosphodiesterase 5 inhibitor to riociguat.
Franck F Rahaghi, Vijay P Balasubramanian, Robert C Bourge, Charles D Burger, Murali M Chakinala, Michael S Eggert, Jean M Elwing, Jeremy Feldman, Christopher King, Ja...> ;Pulmonary Circulation. 2022 Apr 1
4 citations
Physical Activity and Its Association with Traditional Outcome Measures in Pulmonary Arterial Hypertension
Jasleen Minhas, Haochang Shou, Steven G. Hershman, Roham T. Zamanian, Corey E. Ventetuolo, Todd M. Bull, Anna R. Hemnes, Murali M. Chakinala, Stephen C. Mathai, Nadine...> ;Annals of the American Thoracic Society. 2021 Sep 2
17 citations
Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension
Kel Vin Woo, Isabel Y Shen, Carla J. Weinheimer, Attila Kovacs, Jessica M. Nigro, Chieh-Yu Lin, Murali M. Chakinala, Derek E. Byers, David M. Ornitz> ;The Journal of Clinical Investigation. 2021 Sep 1
19 citations
The Prognostic Value of Right Atrial Strain Imaging in Patients with Precapillary Pulmonary Hypertension
Nina E. Hasselberg, Nobuyuki Kagiyama, Yuko Soyama, Masataka Sugahara, Akiko Goda, Keiko Ryo-Koriyama, Omar Batel, Murali M. Chakinala, Marc A. Simon, John Gorcsan> ;Journal of the American Society of Echocardiography. 2021 Mar 24
1 citations
An expert panel delphi consensus statement on patient selection and management for transitioning between oral and inhaled treprostinil.
Franck Rahaghi, Roblee P Allen, Vijay Balasubramanian, Murali M. Chakinala, Jean M. Elwing, Jeremy Feldman, Peter J. Leary, Franz Rischard, Zeenat Safdar, Namita Sood,...> ;Pulmonary Pharmacology & Therapeutics. 2021 Feb 1
6 citations
Patient and disease characteristics of the first 500 patients with pulmonary arterial hypertension treated with selexipag in real-world settings from SPHERE.
Nick H. Kim, Anna R. Hemnes, Murali M. Chakinala, Kristin B. Highland, Kelly Chin, Vallerie V. McLaughlin, Carol Zhao, Veena Narayan, Harrison W. Farber> ;The Journal of Heart and Lung Transplantation. 2021 Jan 15
12 citations
Health disparities and treatment approaches in portopulmonary hypertension and idiopathic pulmonary arterial hypertension: an analysis of the Pulmonary Hypertension As...
Hilary M. DuBrock, Charles D. Burger, Sonja Bartolome, Jeremy Feldman, D. Dunbar Ivy, Erika B. Rosenzweig, J.S. Sager, Kenneth W. Presberg, Stephen C. Mathai, Matthew ...> ;Pulmonary Circulation. 2021 Jun 6
20 citations
United States Pulmonary Hypertension Scientific Registry: Baseline Characteristics.
J. Badlam, David B. Badesch, Eric D. Austin, Raymond L. Benza, Wendy K. Chung, Harrison W. Farber, K. Feldkircher, Adaani E. Frost, Abby Poms, Katie A. Lutz, Michael W...> ;Chest. 2021 Jan 1
158 citations
Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia.
Marie E Faughnan, Johannes J Mager, Steven W Hetts, Valerie A Palda, Kelly Lang-Robertson, Elisabetta Buscarini, Erik Deslandres, Raj S Kasthuri, Andrea Lausman, David...> ;Annals of Internal Medicine. 2020 Dec 15
1 citations
Reducing rates of readmission and development of an outpatient management plan in pulmonary hypertension: lessons from congestive heart failure management.
Justin Dolan, Stacy Mandras, Jinesh Mehta, Viviana Navas, James H. Tarver, Murali M. Chakinala, Franck Rahaghi> ;Pulmonary Circulation. 2020 Dec 7
14 citations
Riociguat: Clinical research and evolving role in therapy
James R. Klinger, Murali M. Chakinala, David Langleben, Stephan Rosenkranz, Olivier Sitbon> ;British Journal of Clinical Pharmacology. 2021 Jul 1
9 citations
Prediction of Health-related Quality of Life and Hospitalization in Pulmonary Arterial Hypertension: The Pulmonary Hypertension Association Registry
Jeff Min, David B. Badesch, Murali M. Chakinala, Jean M. Elwing, Robert P. Frantz, Evelyn M. Horn, James R. Klinger, Matthew R. Lammi, Sula Mazimba, J.S. Sager, Oksana...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Mar 15
4 citations
Residence at moderately high altitude and its relationship with WHO Group 1 pulmonary arterial hypertension symptom severity and clinical characteristics: the Pulmonar...
Shoaib Fakhri, Kelly Hannon, Kelly Moulden, Ryan A. Peterson, Peter Hountras, Todd M. Bull, James P. Maloney, Teresa De Marco, D. Dunbar Ivy, Thenappan Thenappan, J.S....> ;Pulmonary Circulation. 2020 Nov 10
8 citations
Obesity in pulmonary arterial hypertension the pulmonary hypertension association registry
Jeff Min, Rui Feng, David B. Badesch, Erika Berman-Rosenzweig, Charles D. Burger, Murali M. Chakinala, Teresa De Marco, Jeremy Feldman, Anna R. Hemnes, Evelyn M. Horn,...> ;Annals of the American Thoracic Society. 2021 Feb 1
9 citations
Clinical Differences and Outcomes between Methamphetamine-associated and Idiopathic Pulmonary Arterial Hypertension in the Pulmonary Hypertension Association Registry.
Nicholas A. Kolaitis, Roham T. Zamanian, Vinicio A. de Jesus Perez, David B. Badesch, Raymond L. Benza, Charles D. Burger, Murali M. Chakinala, Jean M. Elwing, Jeremy ...> ;Annals of the American Thoracic Society. 2021 Apr 1
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Lectures

Cardiology Update
Washington University School of Medicine, Saint Louis, Missouri - 6/9/2012

Press Mentions

PAH Care Turns Corner with New Therapies, Intensified MonitoringFebruary 8th, 2022
A Deep Dive into Pulmonary HypertensionJanuary 21st, 2019
PhaseBio Announces Dosing of First Patient in Phase 2b Clinical Trial of PB1046 in Pulmonary Arterial HypertensionNovember 27th, 2018
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