
Daphne J Holt MD PhD
Associate Professor of Psychiatry, Harvard Medical School, Massachusetts General Hospital
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149 13th StMgh EastCharlestown, MA 02129
Phone+1 617-726-7618
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Education & Training
Mass General Brigham/Massachusetts General Hospital/McLean HospitalResidency, Psychiatry, 1998 - 2002
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1998
Certifications & Licensure
MA State Medical License 2001 - 2026
American Board of Psychiatry and Neurology Psychiatry
Clinical Trials
- Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness Start of enrollment: 2022 Jul 13
Roles: Contact, Principal Investigator
Publications & Presentations
PubMed
- Visual Deficits in Contrast and Depth Perception in Psychotic Disorders: Implications for a Neural Hierarchy.Baktash Babadi, Daphne J Holt, Roger B H Tootell
Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 2026-03-01 - 1 citationsScreening for Psychotic Experiences and Psychotic Disorders in General Mental Health Treatment Settings: A Systematic Review and Meta-Analysis.Jacqueline A Clauss, Cheryl Y S Foo, Catherine J Leonard, Katherine N Dokholyan, Corinne Cather
Harvard Review of Psychiatry. 2026-01-01 - 5 citationsTransdiagnostic prevention in youth mental health, Part I: rationale, shared risk factors.Daphne J Holt, Karmel W Choi, Nicole R DeTore, Oyenike Balogun
Neuropsychopharmacology. 2026-01-01
Journal Articles
- Research Paper Understanding the Effects of Emotional Reactivity on Depression and Suicidal Thoughts and Behaviors: Moderating Effects of Childhood Adversity and Resil...Benjamin G Shapero, Daphne J Holt, Amy Farabaugh, Joey C Cheung, Maurizio Fava, ScienceDirect
- The Shared Genetic Basis of Educational Attainment and Cerebral Cortical MorphologyJordan W Smoller, Daphne J Holt, Alysa E Doyle, Cerebral Cortex
Press Mentions
LAB DAY 2021 Takes Participants on a Virtual Tour of Research at Mass GeneralSeptember 27th, 2021
How to Maintain Your Mental Well-Being During the COVID-19 CrisisMay 4th, 2020
Why We Need 'Personal Space' and Ways to Deal When People Ignore ItAugust 19th, 2019
Grant Support
- A randomized controlled trial of a preventive behavioral intervention for young adults with psychotic experiencesMASSACHUSETTS GENERAL HOSPITAL2024–2029
- A randomized controlled trial of a preventive behavioral intervention for young adults with psychotic experiencesMASSACHUSETTS GENERAL HOSPITAL2024–2029
- Stable and dynamic neurobehavioral phenotypes of social isolation and loneliness in serious mental illnessMASSACHUSETTS GENERAL HOSPITAL2022–2027
- Stable and dynamic neurobehavioral phenotypes of social isolation and loneliness in serious mental illnessMASSACHUSETTS GENERAL HOSPITAL2022–2027
- Neurobehavioral mechanisms of social isolation and loneliness in serious mental illnessMASSACHUSETTS GENERAL HOSPITAL2021–2026
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