DavidJ.AdamsMD

PubMed

• 3 citations
  Ulcerated Melanoma: Systems Biology Evidence of Inflammatory Imbalance Toward Pro-tumorigenicity.
  John R. Davies, Sathya Muralidhar, Juliette Randerson-Moor, Mark Harland, S.J. O’Shea, Joey Mark S. Diaz, Christy Walker, Jérémie Nsengimana, Jon Laye, Tracey Mell, Ma...> ;Pigment Cell & Melanoma Research. 2021 Nov 26
• 2 citations
  Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for Saturation Genome Editing and other Deep Mutational Scanning exper...
  Luca Barbon, Victoria Offord, Elizabeth J. Radford, Adam Butler, Sebastian S. Gerety, David J. Adams, Hong Kee Tan, Andrew J. Waters> ;Bioinformatics. 2021 Nov 16
• 6 citations
  ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activation
  Arsalan Yousuf, Xiaosa Wu, Anuja R. Bony, Mahsa Sadeghi, Yen-Hua Huang, David J. Craik, David J. Adams> ;Journal of Neurochemistry. 2021 Nov 4
• 12 citations
  Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma.
  Aviyah Peri, Erez Greenstein, Michal Alon, Joy A. Pai, Tamir Dingjan, Shlomit Reich-Zeliger, Eilon Barnea, Chaya Barbolin, Ronen Levy, Claudia Arnedo-Pac, Shelly Kalao...> ;The Journal of Clinical Investigation. 2021 Oct 15
• 6 citations
  Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability.
  Anuja R. Bony, Jeffrey R. McArthur, Rocio K. Finol-Urdaneta, David J. Adams> ;British Journal of Pharmacology. 2021 Oct 1
• 26 citations
  Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines.
  Barbara De Kegel, Niall Quinn, Nicola A. Thompson, David J. Adams, Colm J. Ryan> ;Cell Systems. 2021 Sep 15
• 24 citations
  Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation
  Nathaniel R. Campbell, Anjali Rao, Miranda V. Hunter, Magdalena Katarzyna Sznurkowska, Luzia Briker, Maomao Zhang, Maayan Baron, Silja Heilmann, Maxime Deforet, Colin ...> ;Developmental Cell. 2021 Sep 15
• 3 citations
  Electrical properties and synaptic transmission in mouse intracardiac ganglion neurons in situ
  Alexander A. Harper, David J. Adams> ;Physiological Reports. 2021 Sep 1
• 5 citations
  Ethanol-induced formation of colorectal tumours and precursors in a mouse model of Lynch Syndrome
  Guia Cerretelli, Ying Zhou, Mike-Freya Müller, David J. Adams, Mark J. Arends> ;The Journal of Pathology. 2021 Sep 20
• 18 citations
  Germline ATM variants predispose to melanoma: a joint analysis across the GenoMEL and MelaNostrum consortia.
  Bruna Dalmasso, Lorenza Pastorino, Vaishnavi Nathan, N. N. Shah, Jane M. Palmer, Madeleine Howlie, P. A. Johansson, N. D. Freedman, Brian D. Carter, L. Beane-Freeman, ...> ;Genetics in Medicine. 2021 Jul 14
• 1 citations
  Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4
  Oscar Krijgsman, Kristel Kemper, Julia Boshuizen, David W. Vredevoogd, Elisa A. Rozeman, Sofia Ibanez Molero, Beaunelle de Bruijn, Paulien Cornelissen-Steijger, Aida S...> ;Clinical Cancer Research. 2021 Jul 6
• 9 citations
  More than just acral melanoma: the controversies of defining the disease.
  Sara Santos Bernardes, Ingrid Ferreira, David E. Elder, Aretha B Nobre, Héctor Martínez-Said, David J. Adams, Carla Daniela Robles-Espinoza, Patricia A. Possik> ;The Journal of Pathology. Clinical Research. 2021 Jul 2
• 15 citations
  Comparison of the oncogenomic landscape of canine and feline hemangiosarcoma shows novel parallels with human angiosarcoma.
  Kim Wong, Latasha Ludwig, Oscar Krijgsman, David J Adams, Geoffrey A Wood, Louise van der Weyden> ;Disease Models & Mechanisms. 2021 Jul 1
• 10 citations
  Molecular pathology of skin adnexal tumors
  Jaclyn M Plotzke, David J. Adams, Paul W. Harms> ;Histopathology. 2021 Jul 1
• Cross-species comparison of the oncogenomic landscape of canine and feline hemangiosarcoma shows novel parallels with human angiosarcoma.
  Kim Wong, Latasha Ludwig, Oscar Krijgsman, David J. Adams, Geoffrey A. Wood, Louise van der Weyden> ;Disease Models & Mechanisms. 2021 Jun 23
• 18 citations
  The clinicopathologic spectrum and genomic landscape of de-/trans-differentiated melanoma.
  Ingrid Ferreira, Alastair Droop, Olivia Edwards, Kim Wong, Victoria Harle, Omar Habeeb, Deepa Gharpuray-Pandit, Joseph Houghton, Katharina Wiedemeyer, Thomas Mentzel, ...> ;Modern Pathology. 2021 Jun 21
• 6 citations
  Hi-C scaffolded short- and long-read genome assemblies of the California sea lion are broadly consistent for syntenic inference across 45 million years of evolution
  Claire R. Peart, Christina L. Williams, Saurabh D. Pophaly, Benjamin A. Neely, Frances M. D. Gulland, David J. Adams, Bee Ling Ng, William Cheng, Michael E. Goebel, Ol...> ;Molecular Ecology Resources. 2021 Jun 7
• 24 citations
  Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor.
  Xiao Li, Han-Shen Tae, Yanyan Chu, Tao Jiang, David J. Adams, Rilei Yu> ;Pharmacology & Therapeutics. 2021 Jun 1
• 9 citations
  Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors.
  Han-Shen Tae, Bingmiao Gao, Ai Hua Jin, Paul F. Alewood, David J. Adams> ;Biochemical Pharmacology. 2021 May 29
• 5 citations
  Publisher Correction: Accelerating functional gene discovery in osteoarthritis.
  Natalie C. Butterfield, Katherine F. Curry, Julia Steinberg, Hannah F. Dewhurst, Davide Komla-Ebri, Naila S. Mannan, Anne-Tounsia Adoum, Victoria D. Leitch, John G. Lo...> ;Nature Communications. 2021 May 28
• 7 citations
  α-Conotoxin Bt1.8 from Conus betulinus selectively inhibits α6/α3β2β3 and α3β2 nicotinic acetylcholine receptor subtypes.
  Huying Ning, Biling Huang, Han-Shen Tae, Zhuguo Liu, Shuo Yu, Liang Li, Longxiao Zhang, David J. Adams, Chenyun Guo, Qiuyun Dai> ;Journal of Neurochemistry. 2021 May 19
• 2 citations
  Membrane protein regulators of melanoma pulmonary colonisation identified using a CRISPRa screen and spontaneous metastasis assay in mice.
  Louise van der Weyden, Victoria Offord, Gemma Turner, Agnes Swiatkowska, Anneliese O. Speak, David J. Adams> ;G3. 2021 May 7
• 50 citations
  Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.
  Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M Sergio, Michael R.G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfi...> ;Nature Communications. 2021 May 5
• 11 citations
  Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia.
  Emmanuelle Supper, Saskia S. Rudat, Vivek Iyer, Alastair Droop, Kim Wong, Jean-François Spinella, Patrick Thomas, Guy Sauvageau, David J. Adams, Chi C. Wong> ;Nature Communications. 2021 Apr 30
• 192 citations
  Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
  Stefan C. Dentro, Ignaty Leshchiner, Kerstin Haase, Maxime Tarabichi, Jeff Wintersinger, Amit G. Deshwar, Kaixian Yu, Yulia Rubanova, Geoff Macintyre, Jonas Demeulemee...> ;Cell. 2021 Apr 15
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