DavidApelianMD

PubMed

• 49 citations
  Phase II Study of the GI-4000 KRAS Vaccine After Curative Therapy in Patients With Stage I-III Lung Adenocarcinoma Harboring a KRAS G12C, G12D, or G12V Mutation
  Jamie E. Chaft, Anya Litvak, Maria E. Arcila, Payal R. Patel, Sandra P. D'Angelo, Lee M. Krug, Valerie W. Rusch, Alicia Mattson, Claire Coeshott, Bernard J. Park, Davi...> ;Clinical Lung Cancer. 2014 Nov 1
• 73 citations
  Safety, tolerability and immunogenicity of GS-4774, a hepatitis B virus-specific therapeutic vaccine, in healthy subjects: A randomized study
  Anuj Gaggar, Claire Coeshott, David Apelian, Timothy C. Rodell, Brian R. Armstrong, Gong Shen, G. Mani Subramanian, John G. McHutchison> ;Vaccine. 2014 Sep 3
• 54 citations
  A Whole Recombinant Yeast-Based Therapeutic Vaccine Elicits HBV X, S and Core Specific T Cells in Mice and Activates Human T Cells Recognizing Epitopes Linked to Viral...
  Thomas H. King, Charles B. Kemmler, Zhimin Guo, Derrick Mann, Yingnian Lu, Claire Coeshott, Adam J. Gehring, Antonio Bertoletti, Zi Z. Ho, William E. Delaney, Anuj Gag...> ;Plos One. 2014 Jul 22
• 73 citations
  Phase I trial of a recombinant yeast-CEA vaccine (GI-6207) in adults with metastatic CEA-expressing carcinoma
  Marijo Bilusic, Christopher R. Heery, Philip M. Arlen, Myrna Rauckhorst, David Apelian, Kwong Y. Tsang, Jo A. Tucker, Caroline Jochems, Jeffrey Schlom, James L. Gulley...> ;Cancer Immunology, Immunotherapy. 2014 Mar 1
• 68 citations
  Combination Therapy with a Second-Generation Androgen Receptor Antagonist and a Metastasis Vaccine Improves Survival in a Spontaneous Prostate Cancer Model
  Andressa Ardiani, Benedetto Farsaci, Connie J. Rogers, Andrew Asher Protter, Zhimin Guo, Thomas H. King, David Apelian, James W. Hodge> ;Clinical Cancer Research. 2013 Nov 15
• 52 citations
  Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine.
  Duane H. Hamilton, Mary T. Litzinger, Alessandra Jales, Bruce Huang, Romaine I. Fernando, James W. Hodge, Andressa Ardiani, David Apelian, Jeffrey Schlom, Claudia Palena> ;Oncotarget. 2013 Sep 28
• 18 citations
  Maturation of human dendritic cells with Saccharomyces cerevisiae (yeast) reduces the number and function of regulatory T cells and enhances the ratio of antigen-speci...
  Vittore Cereda, Matteo Vergati, Ngar-Yee Huen, Maria Giovanna di Bari, Caroline Jochems, Chiara Intrivici, James L. Gulley, David Apelian, Jeffrey Schlom, Kwong Y. Tsang> ;Vaccine. 2011 Jul 12
• 54 citations
  Exploitation of differential homeostatic proliferation of T-cell subsets following chemotherapy to enhance the efficacy of vaccine-mediated antitumor responses.
  Sofia R. Gameiro, Jorge A. Caballero, Jack P. Higgins, David Apelian, James W. Hodge> ;Cancer Immunology, Immunotherapy. 2011 May 5
• 11 citations
  Mutation-specific control of BCR-ABL T315I positive leukemia with a recombinant yeast-based therapeutic vaccine in a murine model
  Melanie R. Bui, Victoria Kelley Hodson, Thomas H. King, Derek Leopold, Shaodong Dai, Valerie Fiolkoski, Sarah Oakes, Richard C. Duke, David Apelian, Alex Franzusoff, J...> ;Vaccine. 2010 Aug 23
• 86 citations
  Whole recombinant yeast-based immunotherapy induces potent T cell responses targeting HCV NS3 and Core proteins
  Aurelia Haller, Georg M. Lauer, Thomas H. King, Charles B. Kemmler, Valerie Fiolkoski, Yingnian Lu, Don Bellgrau, Timothy C. Rodell, David Apelian, Alex Franzusoff, Ri...> ;Vaccine. 2007 Feb 9
• 1065 citations
  A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
  Ting-Tsung Chang, Robert G. Gish, Robert A. de Man, Adrián Gadano, Jose D. Sollano, You Chen Chao, Anna S. Lok, Kwang Hyub Han, Zachary Goodman, J. Zhu, Anne Cross, De...> ;The New England Journal of Medicine. 2006 Mar 9
• A new putative sigma factor of Myxococcus xanthus.
  Apelian, D., Inouye, S.> ;J Bacteriol. 1993 Jun
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