David Denofrio MD
Heart Failure & Transplantation
Associate Professor, Medicine, Tufts Medical Center
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750 Washington St# Tufts-NeBoston, MA 02111
Phone+1 617-636-8068
Fax+1 617-636-6030
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Summary
- Dr. David Denofrio is a cardiologist based in Boston, MA, specializing in heart failure and transplantation. He completed his residency in Internal Medicine at Washington University/B-JH/SLCH Consortium and a fellowship in Cardiovascular Disease at Duke University Hospital. Dr. Denofrio graduated from Tufts University School of Medicine in 1988. His research includes various publications on heart transplantation and associated conditions, with notable work published in journals such as The Journal of Heart and Lung Transplantation and ASAIO Journal. He has been involved in clinical trials like the Hyponatremia Registry and has received multiple honors, including CMS Meaningful Use Certifications and being named one of America's Top Doctors by Castle Connolly.
Education & Training
Duke University HospitalFellowship, Cardiovascular Disease, 1991 - 1994
Washington University/B-JH/SLCH ConsortiumResidency, Internal Medicine, 1988 - 1991
Tufts University School of MedicineClass of 1988
Certifications & Licensure
RI State Medical License 1999 - 2028
MA State Medical License 1999 - 2027
NH State Medical License 2009 - 2027
ME State Medical License 2020 - 2021
PA State Medical License 1994 - 2000
NC State Medical License 1992 - 1999
American Board of Internal Medicine Internal Medicine- American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology
- American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification eClinicalWorks, eClinicalWorks, LLC, 2012, 2014-2016
- CMS Meaningful Use Stage 2 Certification eClinicalWorks, eClinicalWorks, LLC, 2012, 2014-2016
- America's Top Doctors Castle Connolly, 2011-2014
Clinical Trials
- Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia Start of enrollment: 2010 Sep 01
Publications & Presentations
PubMed
- 5 citationsTolerability and clinical efficacy of letermovir for primary cytomegalovirus prophylaxis after heart transplantation.Jennifer K L Chow, Amanda R Vest, David DeNofrio, David R Snydman
The Journal of Heart and Lung Transplantation. 2026-01-01 - The Association Between Pulmonary Vascular Resistance and Posttransplant Outcomes Differs by Left Ventricular Assist Device Status.Gaurav Gulati, Melissa R Tsoi, Jenica N Upshaw, Amanda R Vest, David DeNofrio
ASAIO Journal. 2025-03-01 - 1 citationsAssociation of diuretic requirement and right heart failure post-LVAD implantation.Dou Huang, Philip Lacombe, Gaurav Gulati, Gregory S Couper, Masashi Kawabori
JHLT Open. 2024-05-01
Press Mentions
With Gratitude in Every Step: A Husband’s Boston Marathon Tribute to His Wife’s Transplant MilestoneMarch 27th, 2026- Tufts Medical Center Marks 40 Years of Adult Heart Transplant ExcellenceOctober 31st, 2025
- New England’s Heart Transplant ChampionsOctober 30th, 2025
Professional Memberships
- Fellow
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