DavidAllanEberhardMDPhD

PubMed

• 15 citations
  Improved Tumor Purity Metrics in Next-generation Sequencing for Clinical Practice: The Integrated Interpretation of Neoplastic Cellularity and Sequencing Results (IINC...
  Nirali M. Patel, Heejoon Jo, David A. Eberhard, Xiaoying Yin, Michele C. Hayward, Matthew K Stein, David N. Hayes, Juneko E. Grilley-Olson> ;Applied Immunohistochemistry & Molecular Morphology. 2019 Nov 1
• 54 citations
  Enhancing Next‐Generation Sequencing‐Guided Cancer Care Through Cognitive Computing
  Nirali M. Patel, Vanessa V. Michelini, Jeff M. Snell, Saianand Balu, Alan P. Hoyle, Joel S. Parker, Michele C. Hayward, David A. Eberhard, Ashley H. Salazar, Patrick M...> ;The Oncologist. 2018 Feb 1
• 4 citations
  Diagnostic accuracy and prediction increment of markers of epithelial-mesenchymal transition to assess cancer cell detachment from primary tumors.
  Evan L. Busch, Prabhani Kuruppumullage Don, Haitao Chu, David B. Richardson, Temitope O. Keku, David A. Eberhard, Christy L. Avery, Robert S. Sandler> ;BMC Cancer. 2018 Jan 16
• 120 citations
  A Phase 2/3 Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of Lenalidomide Versus Investigator's Choice in Patients with Relapsed or Refr...
  Myron S. Czuczman, Marek Trněný, Andrew Davies, Simon Rule, Kim Linton, Nina D. Wagner-Johnston, Randy D. Gascoyne, Graham W. Slack, Pierre Brousset, David A. Eberhard...> ;Clinical Cancer Research. 2017 Aug 1
• 74 citations
  The molecular basis of breast cancer pathological phenotypes
  Yujing J. Heng, Susan C. Lester, Gary M. Tse, Rachel E. Factor, Kimberly H. Allison, Laura C. Collins, Yunn-Yi Chen, Kristin C. Jensen, Nicole B. Johnson, Jong Cheol J...> ;The Journal of Pathology. 2017 Feb 1
• 10 citations
  Identification of Human Papillomavirus Infection in Cancer Tissue by Targeted Next-generation Sequencing.
  Nathan D. Montgomery, Joel S. Parker, David A. Eberhard, Nirali M. Patel, Karen E. Weck, Norman E. Sharpless, Zhiyuan Hu, David N. Hayes, Margaret L. Gulley> ;Applied Immunohistochemistry & Molecular Morphology. 2016 Aug 1
• 17 citations
  Evaluating markers of epithelial-mesenchymal transition to identify cancer patients at risk for metastatic disease.
  Evan L. Busch, Temitope O. Keku, David B. Richardson, Stephanie M. Cohen, David A. Eberhard, Christy L. Avery, Robert S. Sandler> ;Clinical & Experimental Metastasis. 2016 Jan 1
• 33 citations
  Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberratio...
  Xiaobei Zhao, Anyou Wang, Vonn Walter, Nirali M. Patel, David A. Eberhard, Michele C. Hayward, Ashley H. Salazar, Heejoon Jo, Matthew G. Soloway, Matthew D. Wilkerson,...> ;Plos One. 2015 Jun 15
• 28 citations
  Targeted next generation sequencing identifies clinically actionable mutations in patients with melanoma.
  William R. Jeck, Joel S. Parker, Craig C. Carson, Janiel M. Shields, Maria J. Sambade, Eldon C. Peters, Christin E. Burd, Nancy E. Thomas, Derek Y. Chiang, Wenjin Liu,...> ;Pigment Cell & Melanoma Research. 2014 Jul 1
• 170 citations
  Criteria for the use of omics-based predictors in clinical trials
  Lisa M. McShane, Margaret M. Cavenagh, Tracy Lively, David A. Eberhard, William L. Bigbee, P. Mickey Williams, Jill P. Mesirov, Mei Yin C. Polley, Kelly Y. Kim, James ...> ;Nature. 2013 Oct 17
• 89 citations
  Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration.
  Lisa M. McShane, Margaret M. Cavenagh, Tracy Lively, David A. Eberhard, William L. Bigbee, P. M. Williams, Jill P. Mesirov, Mei Yin C. Polley, Kelly Y. Kim, James V. T...> ;BMC Medicine. 2013 Oct 17
• 97 citations
  Evaluating tumor heterogeneity in immunohistochemistry-stained breast cancer tissue
  Steven J. Potts, Joseph S. Krueger, Nicholas D. Landis, David A. Eberhard, G. David Young, Steven C Schmechel, Holger Lange> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2012 Sep 1
• 5 citations
  Tissue pattern recognition error rates and tumor heterogeneity in gastric cancer.
  Steven J. Potts, Sarah E. Huff, Holger Lange, Vladislav Zakharov, David A. Eberhard, Joseph S. Krueger, David G. Hicks, George David Young, Trevor Johnson, Christa L. ...> ;Applied Immunohistochemistry & Molecular Morphology. 2012 Jul 1
• 780 citations
  Diverse somatic mutation patterns and pathway alterations in human cancers
  Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson, Vasantharajan Janakiraman, Deepali Bhatt, Howard M. Stern, Peng Yue, Peter M. Haverty, Richard Bourgon, Jianbiao Zheng,...> ;Nature. 2010 Aug 12
• 10 citations
  A tumor sorting protocol that enables enrichment of pancreatic adenocarcinoma cells and facilitation of genetic analyses.
  Zachary Boyd, Rajiv Raja, Stephanie Johnson, David A. Eberhard, Mark R. Lackner> ;The Journal of Molecular Diagnostics. 2009 Jul 1
• 255 citations
  Biomarkers of Response to Epidermal Growth Factor Receptor Inhibitors in Non–Small-Cell Lung Cancer Working Group: Standardization for Use in the Clinical Trial Setting
  David A. Eberhard, Giuseppe Giaccone, Bruce E. Johnson> ;Journal of Clinical Oncology. 2008 Feb 20
• 71 citations
  Efficacy and Safety of Single-Agent Pertuzumab, a Human Epidermal Receptor Dimerization Inhibitor, in Patients with Non–Small Cell Lung Cancer
  Roy S. Herbst, Angela M. Davies, Ronald B. Natale, Thao P. Dang, Joan H. Schiller, Linda L. Garland, Vincent A. Miller, David S. Mendelson, Annick D. Van den Abbeele, ...> ;Clinical Cancer Research. 2007 Oct 15
• 6 citations
  Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection.
  Brock A. Peters, Zhengyan Kan, Dragan Sebisanovic, Kanan Pujara, Zhiyong Wang, Peter Hong, Bernard Chow, Jeremy Stinson, Victoria Carlton, Thinh Pham, Howard M. Stern,...> ;Nature Methods. 2007 Aug 19
• 188 citations
  Clinical Activity of Pertuzumab (rhuMAb 2C4), a HER Dimerization Inhibitor, in Advanced Ovarian Cancer: Potential Predictive Relationship With Tumor HER2 Activation St...
  Michael S. Gordon, Daniela Matei, Carol Aghajanian, Ursula A. Matulonis, Molly Brewer, Gini F. Fleming, John D. Hainsworth, Agustin A. Garcia, Mark D. Pegram, Russell ...> ;Journal of Clinical Oncology. 2006 Sep 10
• 423 citations
  Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients.
  Robert L. Yauch, Thomas Januario, David A. Eberhard, Guy Cavet, Wenjing Zhu, Ling Fu, Thinh Pham, Robert Soriano, Jeremy Stinson, Somasekar Seshagiri, Zora Modrusan, C...> ;Clinical Cancer Research. 2005 Dec 15
• 1202 citations
  Mutations in the Epidermal Growth Factor Receptor and in KRAS Are Predictive and Prognostic Indicators in Patients With Non–Small-Cell Lung Cancer Treated With Chemoth...
  David A. Eberhard, Bruce E. Johnson, Lukas C. Amler, Audrey Goddard, Sherry Heldens, Roy S. Herbst, William L. Ince, Pasi A. Jänne, Thomas Januario, David H. Johnson, ...> ;Journal of Clinical Oncology. 2005 Sep 1
• 372 citations
  Epidermal Growth Factor Receptor, Protein Kinase B/Akt, and Glioma Response to Erlotinib
  Daphne A. Haas-Kogan, Michael D. Prados, Tarik Tihan, David A. Eberhard, Nannette Jelluma, Nils D. Arvold, Rachel Baumber, Kathleen R. Lamborn, Ami Kapadia, Mary Malec...> ;Journal of the National Cancer Institute. 2005 Jun 15
• 419 citations
  Phase I/II Trial Evaluating the Anti-Vascular Endothelial Growth Factor Monoclonal Antibody Bevacizumab in Combination With the HER-1/Epidermal Growth Factor Receptor ...
  Roy S. Herbst, David H. Johnson, Eric Mininberg, David P. Carbone, Ted Henderson, Edward S. Kim, George R. Blumenschein, Jack Lee, Diane D. Liu, Mylene T. Truong, Waun...> ;Journal of Clinical Oncology. 2005 Apr 10
• 21 citations
  GEPIS---quantitative gene expression profiling in normal and cancer tissues
  Yan Zhang, David A. Eberhard, Gretchen Frantz, Patrick Dowd, Thomas D. Wu, Yan Zhou, Colin K. Watanabe, Shiuh-Ming Luoh, Paul Polakis, Kenneth J. Hillan, William I. Wo...> ;Bioinformatics. 2004 Oct 12
• 29 citations
  Early Treatment with Hepatocyte Growth Factor Improves Cardiac Function in Experimental Heart Failure Induced by Myocardial Infarction
  Hongkui Jin, Renhui Yang, Wei Li, Annie Ogasawara, Ralph H. Schwall, David A. Eberhard, Zhong Zheng, David W. Kahn, Nicholas F. Paoni> ;The Journal of Pharmacology and Experimental Therapeutics. 2003 Feb 1
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