DavidHGutmannMDPhD

PubMed

• Brain injury drives optic glioma formation through neuron-glia signaling.
  Chatterjee, J., Koleske, J., Chao, A., Sauerbeck, A., Chen, J., Qi, X., Ouyang, M., Boggs, L., Idate, R., Marco Y Marquez, L., Kummer, T., Gutmann, D.> ;Acta Neuropathologica Communications. 2024 Feb 2
• 14 citations
  BRAF mutations may identify a clinically distinct subset of glioblastoma.
  Samantha N. McNulty, Katherine E. Schwetye, Cole J. Ferguson, Chad Storer, George Ansstas, Albert H. Kim, David H. Gutmann, Joshua B. Rubin, Richard D. Head, Sonika Da...> ;Scientific Reports. 2021 Oct 8
• 24 citations
  Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis
  Michelle L. Wegscheid, Corina Anastasaki, Kelly Hartigan, Olivia Cobb, Jason B. Papke, Jennifer N. Traber, Stephanie M. Morris, David H. Gutmann> ;Cell Reports. 2021 Jul 6
• 13 citations
  Reimagining pilocytic astrocytomas in the context of pediatric low-grade gliomas
  Till Milde, Fausto J. Rodriguez, Jill S. Barnholtz-Sloan, Nirav Patil, Charles G. Eberhart, David H. Gutmann> ;Neuro-Oncology. 2021 Oct 1
• 1 citations
  Familial Lipomas Without Classic Neurofibromatosis-1 Caused by a Missense Germline NF1 Mutation.
  Erika Ramirez, Stephanie M. Morris, Tychele N. Turner, David H. Gutmann> ;Neurology. Genetics. 2021 Mar 26
• 15 citations
  RNA sequence analysis reveals ITGAL/CD11A as a stromal regulator of murine low-grade glioma growth.
  Amanda De Andrade Costa, Jit Chatterjee, Olivia Cobb, Shilpa Sanapala, Xiaofan Guo, Sonika Dahiya, David H. Gutmann> ;Neuro-Oncology. 2021 May 27
• 70 citations
  NF1 mutation drives neuronal activity-dependent initiation of optic glioma
  Yuan Pan, Jared D. Hysinger, Tara Barron, Nicki F. Schindler, Olivia Cobb, Xiaofan Guo, Belgin Yalçın, Corina Anastasaki, Sara B. Mulinyawe, Anitha Ponnuswami, Suzanne...> ;Nature. 2021 May 26
• 243 citations
  Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation.
  Eric Legius, Ludwine Messiaen, Pierre Wolkenstein, P Pancza, Robert A. Avery, Yemima Berman, J. Blakeley, Dusica Babovic-Vuksanovic, Karin Soares Gonçalves Cunha, Rosa...> ;Genetics in Medicine. 2021 May 19
• 7 citations
  Visual outcomes following everolimus targeted therapy for neurofibromatosis type 1‐associated optic pathway gliomas in children
  Nicole J. Ullrich, Sanjay P. Prabhu, Roger J. Packer, Stewart Goldman, Nathan Robison, Jeffrey C. Allen, David Viskochil, David H. Gutmann, John P. Perentesis, Bruce R...> ;Pediatric Blood & Cancer. 2021 Apr 1
• 25 citations
  Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).
  Michael Fisher, David T.W. Jones, Yimei Li, Xiaofan Guo, Poonam Sonawane, Angela J. Waanders, Joanna J. Phillips, William A. Weiss, Adam C. Resnick, Sara J. C. Gosline...> ;Acta Neuropathologica. 2021 Feb 14
• 5 citations
  Autism in neurofibromatosis type 1: misuse of covariance to dismiss autistic trait burden
  Stephanie M. Morris, Maria T. Acosta, Shruti Garg, Jonathan Green, Eric Legius, Kathryn N. North, Jonathan M. Payne, Lauren A. Weiss, John N. Constantino, David H. Gut...> ;Developmental Medicine and Child Neurology. 2021 Feb 1
• 9 citations
  Global microRNA profiling identified miR-10b-5p as a regulator of neurofibromatosis 1 (NF1)-glioma migration.
  J. S. Nix, Ming Yuan, Eddie Luidy Imada, H. Ames, Luigi Marchionni, David H. Gutmann, Fausto J. Rodriguez> ;Neuropathology and Applied Neurobiology. 2021 Feb 1
• 33 citations
  Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial.
  Michael Fisher, Chie-Schin Shih, Steven D. Rhodes, Amy E. Armstrong, Pamela L. Wolters, Eva Dombi, Chi Zhang, Steven P. Angus, Gary L. Johnson, Roger J. Packer, Jeffre...> ;Nature Medicine. 2021 Jan 13
• 31 citations
  Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins.
  Juan Mo, Corina Anastasaki, Zhiguo Chen, Tracey Shipman, Jason B. Papke, Kevin Y. Yin, David H. Gutmann, Lu Q. Le> ;The Journal of Clinical Investigation. 2021 Jan 4
• 3 citations
  Immune cell analysis of pilocytic astrocytomas reveals sexually dimorphic brain region-specific differences in T-cell content.
  Jie Chen, Namita Sinha, Olivia Cobb, Collin Liu, Ayca Ersen, Joanna J. Phillips, Tarik Tihan, David H. Gutmann, Sonika Dahiya> ;Neuro-Oncology Advances. 2021 Jan 1
• 5 citations
  Shared developmental gait disruptions across two mouse models of neurodevelopmental disorders.
  Rachel M. Rahn, Claire Weichselbaum, David H. Gutmann, Joseph D. Dougherty, Susan E. Maloney> ;Journal of Neurodevelopmental Disorders. 2021 Mar 20
• 5 citations
  SRF Is Required for Maintenance of Astrocytes in Non-Reactive State in the Mammalian Brain.
  Monika Jain, Soumen Das, Paul P. Y. Lu, Garima Virmani, Sumitha Soman, Surya Chandra Rao Thumu, David H. Gutmann, Narendrakumar Ramanan> ;Eneuro. 2021 Jan 1
• 5 citations
  Visual field outcomes in children treated for neurofibromatosis type 1-associated optic pathway gliomas: a multicenter retrospective study.
  Gena Heidary, Michael Fisher, Grant T. Liu, Rosalie E. Ferner, David H. Gutmann, Robert Listernick, Kush Kapur, Michael J. Loguidice, Simone L. Ardern-Holmes, Robert A...> ;Journal of AAPOS. 2020 Nov 20
• 37 citations
  Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.
  Audrey Yi Tyan Peng, Ira Agrawal, Wan Yun Ho, Yi-Chun Yen, Ashley J. Pinter, Jerry Liu, Qi Xuan Cheryl Phua, Katrianne Bethia Koh, Jer-Cherng Chang, Emma Sanford, Jodi...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Nov 17
• 5 citations
  Temporal, spatial, and genetic constraints contribute to the patterning and penetrance of murine neurofibromatosis-1 optic glioma.
  Nicole M. Brossier, Sharanya Thondapu, Olivia Cobb, Sonika Dahiya, David H. Gutmann> ;Neuro-Oncology. 2021 Apr 12
• 26 citations
  Junctional Adhesion Molecules in Cancer: A Paradigm for the Diverse Functions of Cell-Cell Interactions in Tumor Progression.
  Adam Lauko, Zhaomei Mu, David H. Gutmann, Ulhas P. Naik, Justin D. Lathia> ;Cancer Research. 2020 Aug 14
• 8 citations
  Neurofibromatosis 1 - Mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects.
  Nirmeen Elmadany, Francesca Logiacco, Alice Buonfiglioli, Verena Haage, Elizabeth C. Wright-Jin, Alexander Schattenberg, Roxane M. Papawassiliou, Helmut Kettenmann, Ma...> ;Neurobiology of Disease. 2020 Oct 1
• 34 citations
  How Support of Early Career Researchers Can Reset Science in the Post-COVID19 World.
  Erin M. Gibson, F. Chris Bennett, Shawn M. Gillespie, Ali D. Güler, David H. Gutmann, Casey H. Halpern, Sarah Kucenas, Clete A. Kushida, Mackenzie Lemieux, Shane A. Li...> ;Cell. 2020 Jun 25
• 72 citations
  Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth
  Xiaofan Guo, Yuan Pan, Min Xiong, Shilpa Sanapala, Corina Anastasaki, Olivia Cobb, Sonika Dahiya, David H. Gutmann> ;Nature Communications. 2020 May 1
• 12 citations
  Nonoptic pathway tumors in children with neurofibromatosis type 1
  Jasia Mahdi, Manu S. Goyal, Jennifer Griffith, Stephanie M. Morris, David H. Gutmann> ;Neurology. 2020 Apr 16
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