DavidBruceHaslamMD

PubMed

• Thermoneutral Housing Enables Studies of Vertical Transmission of Obesogenic Diet-Driven Metabolic Diseases.
  Wayland, J., Doll, J., Lawson, M., Stankiewicz, T., Oates, J., Sawada, K., Damen, M., Alarcon, P., Trout, A., Woo, J., Moreno-Fernandez, M., Divanovic, S., Haslam, D.,...> ;Nutrients. 2023 Nov 29
• Acute pancreatitis is associated with gut dysbiosis in children.
  Chinenye R Dike, Nicholas J Ollberding, Tyler Thompson, Nicole Kotha, Phillip Minar, David S Vitale, Tom K Lin, Alexander Nasr, Lee A Denson, David B Haslam, Maisam Ab...> ;Digestive and Liver Disease. 2024 Mar 1
• Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation.
  Tzu-Yu Shao, Tony T Jiang, Joseph Stevens, Abigail E Russi, Ty D Troutman, Anas Bernieh, Giang Pham, John J Erickson, Emily M Eshleman, Theresa Alenghat, Stephen C Jam...> ;Cell Reports. 2023 Nov 28
• 3 citations
  Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth.
  Florian Wimmers, Allison R Burrell, Yupeng Feng, Hong Zheng, Prabhu S Arunachalam, Mengyun Hu, Sara Spranger, Lindsay E Nyhoff, Devyani Joshi, Meera Trisal, Mayanka Aw...> ;Cell. 2023 Oct 12
• 4 citations
  IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation.
  Garrett R Overcast, Hannah E Meibers, Emily M Eshleman, Irene Saha, Lisa Waggoner, Krupaben N Patel, Viral G Jain, David B Haslam, Theresa Alenghat, Kelli L VanDussen,...> ;The Journal of Experimental Medicine. 2023 Jun 5
• 4 citations
  The microbiome in adolescents with irritable bowel syndrome and changes with percutaneous electrical nerve field stimulation.
  Lee A Denson, David B Haslam, Kevin A Hommel, Nicholas J Ollberding, Rashmi Sahay, Neha R Santucci, Castillo, D.> ;Neurogastroenterology and Motility. 2023 Jul 1
• Airway transcriptome networks identify susceptibility to frequent asthma exacerbations in children.
  Kieran J Phelan, Kimberly A Dill-McFarland, Arjun Kothari, R Max Segnitz, Jeff Burkle, Brittany Grashel, Seth Jenkins, Daniel Spagna, Lisa J Martin, David B Haslam, Jo...> ;The Journal of Allergy and Clinical Immunology. 2023 Jul 1
• 13 citations
  Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity.
  Emily M Eshleman, Tzu-Yu Shao, Vivienne Woo, Taylor Rice, Laura Engleman, Bailey J Didriksen, Jordan Whitt, David B Haslam, Sing Sing Way, Theresa Alenghat> ;The Journal of Clinical Investigation. 2023 Feb 15
• 1 citations
  Systems biological assessment of the temporal dynamics of immunity to a viral infection in the first weeks and months of life.
  Florian Wimmers, Allison R Burrell, Yupeng Feng, Hong Zheng, Prabhu S Arunachalam, Mengyun Hu, Sara Spranger, Lindsay Nyhoff, Devyani Joshi, Meera Trisal, Mayanka Awas...> ;Medrxiv. 2023 Jan 31
• 5 citations
  Gut Microbiome Composition and Metabolic Capacity Differ bySecretor Status in Exclusively Breastfed Infants.
  Alexander W Thorman, Grace Adkins, Shannon C Conrey, Allison R Burrell, Ying Yu, Brendon White, Rachel Burke, David Haslam, Daniel C Payne, Mary A Staat, Ardythe L Mor...> ;Nutrients. 2023 Jan 16
• 1 citations
  Delayed Microbial Maturation Durably Exacerbates Th17-driven Asthma in Mice.
  Adrienne N Wilburn, Jaclyn W McAlees, David B Haslam, Simon Graspeuntner, Inken Schmudde, Yves Laumonnier, Jan Rupp, Claire A Chougnet, Hitesh Deshmukh, William J Zach...> ;American Journal of Respiratory Cell and Molecular Biology. 2023 May 1
• Gas Leak in the Port: Portal Venous Gas Associated With Congenital Cytomegalovirus Colitis.
  Kentaro Tominaga, David Haslam, Akihiro Asai> ;JPGN Reports. 2022 Nov 1
• 4 citations
  Single Site Experience of the use of Monoclonal Antibodies for the Treatment of COVID-19 in High-risk Pediatric and Young Adult Patients.
  Hannah Bahakel, Catherine Murphy, Robert W Frenck Jr, Michael S Grimley, Rebecca A Marsh, Grant C Paulsen, David B Haslam, Christine L Phillips, Paul Spearman, Grant S...> ;The Pediatric Infectious Disease Journal. 2022 Dec 1
• 9 citations
  Friendly fungi: symbiosis with commensal Candida albicans.
  Tzu-Yu Shao, David B Haslam, Richard J Bennett, Sing Sing Way> ;Trends in Immunology. 2022 Sep 1
• 1 citations
  Multi-omic characterization of pediatric ARDS via nasal brushings.
  James G Williams, Rashika Joshi, David Haslam, Nadir Yehya, Rhonda L Jones, Aditi Paranjpe, Mario Pujato, Krishna M Roskin, Patrick M Lahni, Hector R Wong, Brian M Var...> ;Respiratory Research. 2022 Jul 9
• 7 citations
  Antibiotic exposure prevents acquisition of beneficial metabolic functions in the preterm infant gut microbiome.
  Yanping Xu, Olivia Milburn, Traci Beiersdorfer, Lizhong Du, Henry Akinbi, David B Haslam> ;Microbiome. 2022 Jul 7
• 15 citations
  Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity.
  Tzu-Yu Shao, Pallavi Kakade, Jessica N Witchley, Corey Frazer, Kathryn L Murray, Iuliana V Ene, David B Haslam, Thomas Hagan, Suzanne M Noble, Richard J Bennett, Sing ...> ;Cell Reports. 2022 May 17
• Aligning Provider Prescribing With Guidelines for Soft Tissue Infections.
  Christopher Kovaleski, Joshua D Courter, Enas Ghulam, Philip A Hagedorn, David B Haslam, Eileen Murtagh Kurowski, James Rudloff, Rhonda Szczesniak, Judith W Dexheimer> ;Pediatric Emergency Care. 2022 Mar 1
• 2 citations
  Future Applications of Metagenomic Next-Generation Sequencing for Infectious Diseases Diagnostics.
  David B Haslam> ;Journal of the Pediatric Infectious Diseases Society. 2021 Dec 24
• 20 citations
  Lethal pediatric cerebral vasculitis triggered by Severe Acute Respiratory Syndrome Coronavirus 2: a case report
  Kelsey E. Poisson, Alexander Zygmunt, Daniel Leino, Christine Fuller, Blaise V. Jones, David B. Haslam, Mary Allen Staat, Gwendolyn M. Clay, Tracy V. Ting, Kristen Wes...> ;Pediatric Neurology. 2021 Nov 12
• 33 citations
  Commensal segmented filamentous bacteria-derived retinoic acid primes host defense to intestinal infection.
  Vivienne Woo, Emily M. Eshleman, Seika Hashimoto-Hill, Jordan Whitt, Shu-en Wu, Laura Engleman, Taylor Rice, Rebekah Karns, Joseph E. Qualls, David B. Haslam, Bruce A....> ;Cell Host & Microbe. 2021 Oct 21
• 14 citations
  Phenotype-Agnostic Molecular Subtyping of Neurodegenerative Disorders: The Cincinnati Cohort Biomarker Program (CCBP).
  Andrea Sturchio, Luca Marsili, Joaquin A. Vizcarra, Alok Dwivedi, Marcelo Andrés Kauffman, Andrew P. Duker, Peixin Lu, Michael W. Pauciulo, Benjamin D. Wissel, Emily J...> ;Frontiers in Aging Neuroscience. 2020 Oct 8
• 8 citations
  Improving Oral Health and Modulating the Oral Microbiome to Reduce Bloodstream Infections from Oral Organisms in Pediatric and Young Adult Hematopoietic Stem Cell Tran...
  Priscila Badia, Heidi Andersen, David Haslam, Adam S. Nelson, Abigail Pate, Sara Golkari, Ashley Teusink-Cross, Laura Flesch, Ashely Bedel, Victoria Hickey, Kathi Kram...> ;Biology of Blood and Marrow Transplantation. 2020 Sep 1
• 18 citations
  Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice.
  Shinsmon Jose, Anindita Mukherjee, Olivia Horrigan, Kenneth D.R. Setchell, Wujuan Zhang, Maria E. Moreno-Fernandez, Heidi Andersen, Divya Sharma, David B. Haslam, Sena...> ;Mucosal Immunology. 2021 Mar 1
• 109 citations
  Microbiota-derived metabolite promotes HDAC3 activity in the gut
  Shu-en Wu, Seika Hashimoto-Hill, Vivienne Woo, Emily M. Eshleman, Jordan Whitt, Laura Engleman, Rebekah Karns, Lee A. Denson, David B. Haslam, Theresa Alenghat> ;Nature. 2020 Jul 30
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Journal Articles

• Antibiotic Exposure and Reduced Short Chain Fatty Acid Production After Hematopoietic Stem Cell Transplant  
  David B Haslam, Lee Denson, Christopher E Dandoy, Stella M Davies, Biology of Blood and Marrow Transplantation
• Performance of the check-points check-MDR CT103XL assay utilizing the CDC/FDA antimicrobial resistance isolate bank  
  Powell EA, Haslam D, Mortensen JE, Diagn Microbiol Infect Dis, 1/1/2017
• Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling  
  Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, et al, Nature Medicine, 1/1/2017
• Metagenomic Approach for Identification of the Pathogens Associated with Diarrhea in Stool Specimens  
  Zhou Y, Wylie KM, El Feghaly RE, Mihindukulasuriya KA, Elward A, Haslam DB, Storch GA, Weinstock GM, J Clin Microbiol, 1/1/2016
• Frequency of Multidrug-Resistant Organisms Cultured From Urine of Children Undergoing Clean Intermittent Catheterization  
  Forster CS, Courter J, Jackson EC, Mortensen JE, Haslam DB, Journal of the Pediatric Infectious Diseases Society, 1/1/2016
• Frequency and risks associated with Clostridium difficile-associated diarrhea after pediatric solid organ transplantation: a single-center retrospective review  
  Ciricillo J, Haslam D, Blum S, Kim M-O, Liu C, Paulsen G, Courter J, Danziger-Isakov L, Transplant infectious disease: an official journal of the Transplantation Society, 1/1/2016
• Use of Shotgun Metagenome Sequencing to Detect Fecal Colonization with Multi-Drug Resistant Bacteria  
  Andersen HM, Connolly NV, Bangar H, Staat M, Mortensen J, Deburger B, Haslam DB, J Clin Microbiol, 1/1/2016
• The molecular basis of Clostridium difficile disease and host response  
  El Feghaly RE, Bangar H, Haslam DB, Curr Opin Gastroenterol, 1/1/2015
• Viral Co-infections are Common and are Associated with Higher Bacterial Burden in Children with C difficile Infection  
  El Feghaly RE, Stauber JL, Tarr PI, Haslam DB, J Pediatr Gastroenterol Nutr, 1/1/2013
• Intestinal Inflammatory Biomarkers and Outcome in Pediatric Clostridium difficile Infections  
  El Feghaly RE, Stauber JL, Tarr PI, Haslam DB, J Pediatr, 1/1/2013
• Markers of intestinal inflammation, not bacterial burden, correlate with clinical outcomes in Clostridium difficile infection  
  El Feghaly RE, Stauber JL, Deych E, Gonzalez C, Tarr PI, Haslam DB, Clin Infect Dis, 1/1/2013
• Robert Haslam: An Autobiography from a Canadian Perspective  
  Haslam RHA, J Child Neurol, 1/1/2005
• Forssman Synthetase Expression Results in Diminished Shiga Toxin Susceptibility: a Role for Glycolipids in Determining Host-Microbe Interactions  
  Elliott SP, Yu M, Xu H, Haslam DB, Infection and Immunity, 1/1/2003
• Expression cloning of human globoside synthase cDNAs Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactos-aminyl...  
  Okajima T, Nakamura Y, Uchikawa M, Haslam DB, Numata SI, Furukawa K, Urano T, J Biol Chem, 1/1/2000
• Molecular Decoys: Novel Approaches to the Prevention of Hemolytic Uremic Syndrome  
  Haslam DB, Pediatr Res, 1/1/2000
• Characterization of the Human Forssman Synthetase Gene  
  Xu H, Storch T, Yu M, Elliott SP, Haslam DB, J. Biol. Chem, 1/1/1999
• Expression cloning of the Forssman synthetase gene : A novel member of the histo-blood group ABO gene family  
  Haslam DB, Baenziger JU, Proc Natl Acad Sci U S A, 1/1/1996
• Molecular dissection of PapD interaction with PapG reveals two chaperone-binding sites  
  Xu Z, Jones CH, Haslam D, Pinkner JS, Dodson K, Kihlberg J, Hultgren SJ, Molecular Microbiology, 1/1/1995
• The Gal(a1-4)Gal-specific tip adhesin of Escherechia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract  
  Roberts JA, Marklund B-I, Ilver D, Haslam D, M.B. K, G. B, M. L, R. M, J. W, S N, Proc.Natl.Acad.Sci. USA, 1/1/1994
• Disseminated measles infection after vaccination in a child with a congenital immunodeficiency  
  Monafo WJ, Haslam DB, Roberts RL, Zaki SR, Bellini WJ, Coffin CM, Journal of Pediatrics, 1/1/1994
• The amino-terminus of the P-pilus adhesin determines receptor specificity  
  Haslam DB, Boren T, Falk P, Ilver D, Chou A, Xu Z, Normark S, Mol. Microbiol., 1/1/1994
• Bacterial adhesion and colonization assays  
  Falk P, Boren T, Haslam D, Caparon M, Methods in Cell Biology, 1/1/1994
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Books/Book Chapters

• Medical and Psychosocial Problems in the Classroom 
  Chapter: Infectious Diseases in the Classroom 
  Page 1.0 - 30.0Haslam DB, Andersen HAEditors: Haslam, RHA, Valletuti, R.ProEd, AustinEdition 5th,2016
• Rudolph’s Pediatrics 
  Chapter: Fever in Immunocompromised Patients 
  McKinney JM, Haslam DBEditors: Rudolph CD, Rudolph AM.McGraw-Hill, New York, NYEdition 22nd,2011
• Nelson Textbook of Pediatrics 
  Chapter: Enterococcus 
  Page 884.0 - 886.0Haslam DBEditors: Behrman RD, Kliegman RM, Jenson HB.Saunders, Pennsylvania, PAEdition 17th,2009
• Bacterial Pili 
  Chapter: Structure, Function, and Biogenesis of Escherichia coli P-pili 
  Kuehn MJ, Haslam D, Normark S, Hultgren SEditors: Klemm P.1994
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