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200 1st St SwRochester, MN 55905
Phone+1 507-284-2511
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Summary
- Dr. David Knopman is a neurologist at the Mayo Clinic, Rochester. He received his medical degree from University of Minnesota Medical School and has been in practice 42 years. He specializes in neurodegenerative and dementia & geriatrics.
Education & Training
University of MinnesotaResidency, Neurology, 1976 - 1979
Hennepin HealthcareInternship, Transitional Year, 1975 - 1976
University of Minnesota Medical SchoolClass of 1975
Dartmouth CollegeA.B., Biology, 1972
Certifications & Licensure
MN State Medical License 1978 - 2026
American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification Centricity Enterprise, GE Healthcare, 2014-2016
- CMS Meaningful Use Stage 1 Certification Centricity Patient Online, GE Healthcare, 2014-2016
- CMS Meaningful Use Stage 2 Certification Centricity Patient Online, GE Healthcare, 2014-2016
Clinical Trials
- The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF) Start of enrollment: 2014 Jan 08
- Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss Start of enrollment: 2014 Feb 28
Publications & Presentations
PubMed
- Contingency of Plasma Dementia Biomarkers on Cognitive Profiles for Prognosis of Incident Dementia: The ARIC Study.David S Knopman, James Russell Pike, Michael Griswold, Yifei Lu, Alden Gross
Neurology. 2026-04-14 - Breakpoints in Alzheimer's disease biomarkers and cognition across the aging spectrum: The Mayo Clinic Study of Aging.Mingzhao Hu, David S Knopman, Terry Therneau, Angela J Fought, Ekaterina Hofrenning
Alzheimer's & Dementia. 2026-04-01 - Skin Biopsy for Phosphorylated α-Synuclein in Mild Cognitive Impairment or Dementia Due to Lewy Body Disease in a Convenience Cohort from a Subspecialty Behavioral Neu...Michael J Rigby, Hugo Botha, Leland R Barnard, R Ross Reichard, Rachel Larsen
Movement Disorders. 2026-04-01
Journal Articles
- Association of Initial Β-amyloid Levels with Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive ImpairmentDavid S Knopman, Bradley F Boeve, Ronald C Petersen, Clifford R Jack, JAMA Neurology
- Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated with MAPT, GRN, and C9orf72 Pathogenic VariantsNupur Ghoshal, Neill R Graff-Radford, David S Knopman, Zbigniew K Wszolek, Joel H Kramer, Bradley F Boeve, Howard J Rosen, JAMA Network Open
- Association Between Functional Performance and Alzheimer's Disease Biomarkers in Individuals Without DementiaMary M Machulda, Ronald C Petersen, David S Knopman, Yonas E Geda, Journal of the American Geriatrics Society
Books/Book Chapters
Abstracts/Posters
- Tdp-43 influences cognition, memory loss and hippocampal atrophy in Alzheimer's disease.Josephs K, Whitwell J, Weigand S, Murray M, Tosakulwong N, Liesinger A, Petrucelli L, Knopman D, Boeve B, Ivnik R, Smith G, Jack C, Parisi J, Petersen R, Dickson D, J Neuropathol Exp Neurol, 6/1/2014
- Antemortem characterization of a kindred carrying the non-coding GGGGCC hexanucleotide repeat expansion in C9ORF72.Adeli A, Boeve B, DeJesus-Hernandez M, Baker M, Rutherford N, Knopman D, Ivnik R, Fields J, Petersen R, Rademakers R, Neurology, 4/1/2012
- Characterization of the neuropsychiatric features associated with mutations in C9ORF72'MAPT and PGRN.Adeli A, Geda Y, Boeve B, Graff-Radford N, DeJesus-Hernandez M, Knopman D, Josephs K, Pedraza O, Rush B, Fields J, Rutherford N, Baker M, Smith G, Ivnik R, Pankratz V,..., Neurology, 4/1/2012
Press Mentions
Long COVID Cognitive Symptoms: RECOVER-NEURO Trial ResultsNovember 10th, 2025
First Guideline on Alzheimer’s Blood-Based Biomarker Tests ReleasedJuly 31st, 2025
United States Dementia Cases Estimated to Double by 2060January 13th, 2025
Grant Support
- Validating The New Criteria For Preclinical Alzheimer'S DiseaseNational Institute On Aging2012
- Frontotemporal Degeneration: A Basis For Clinical TrialsNational Institute On Aging2004–2006
- Frontotemporal Degeneration: A Basis For Clinical TrialsNational Institute On Aging2003
- Epidemiology Of Alzheimer Disease In A Total PopulationNational Institute On Aging1992–1994
- Scientific Evaluation And PlanningNational Institute Of Mental Health1991–1994
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