DavidJavierLopezMD

PubMed

• 14 citations
  The Novel Anticancer Drug Hydroxytriolein Inhibits Lung Cancer Cell Proliferation via a Protein Kinase Cα– and Extracellular Signal-Regulated Kinase 1/2–Dependent Mech...
  Francisca Guardiola-Serrano, Roberto Beteta-Göbel, Raquel Rodríguez-Lorca, Maitane Ibarguren, David J. López, Silvia Terés, Rafael Álvarez, María Alonso-Sande, Xavier ...> ;The Journal of Pharmacology and Experimental Therapeutics. 2015 Aug 1
• 65 citations
  Regulation of the cancer cell membrane lipid composition by NaCHOleate: effects on cell signaling and therapeutical relevance in glioma.
  Victoria Lladó, David J. López, Maitane Ibarguren, María Alonso, Joan B. Soriano, Pablo V. Escribá, Xavier Busquets> ;Biochimica Et Biophysica Acta. 2014 Jun 1
• 19 citations
  The effect of hydroxylated fatty acid-containing phospholipids in the remodeling of lipid membranes
  Stefano Piotto, Alfonso Trapani, Erminia Bianchino, Maitane Ibarguren, David J. López, Xavier Busquets, Simona Concilio> ;Biochimica Et Biophysica Acta. 2014 Jun 1
• 18 citations
  Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.
  Stefano Piotto, Simona Concilio, Erminia Bianchino, Pio Iannelli, David J. López, Silvia Terés, Maitane Ibarguren, Gwendolyn Barceló-Coblijn, Maria Laura Martin, Franc...> ;Biochimica Et Biophysica Acta. 2014 Jun 1
• 180 citations
  The effect of natural and synthetic fatty acids on membrane structure, microdomain organization, cellular functions and human health
  Maitane Ibarguren, David J. López, Pablo V. Escribá> ;Biochimica Et Biophysica Acta. 2014 Jun 1
• 47 citations
  Membrane lipid modifications and therapeutic effects mediated by hydroxydocosahexaenoic acid on Alzheimer's disease.
  Manuel Torres, Samantha L. Price, Maria A. Fiol-deRoque, Amaia Marcilla-Etxenike, Hasna Ahyayauch, Gwendolyn Barceló-Coblijn, Silvia Terés, Loukia Katsouri, Margarita ...> ;Biochimica Et Biophysica Acta. 2014 Jun 1
• Changes in membrane organization upon spontaneous insertion of 2-hydroxylated unsaturated fatty acids in the lipid bilayer.
  Khmelinskaia A, Ibarguren M, de Almeida RFM, López DJ, Paixão VA, Ahyayauch H, Goñi FM, Escribá PV> ;Langmuir. 2014-03-04
• 40 citations
  Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives.
  Maitane Ibarguren, David J. López, José Antonio Encinar, José M. González-Ros, Xavier Busquets, Pablo V. Escribá> ;Biochimica Et Biophysica Acta. 2013 Nov 1
• Imaging the early stages of phospholipase C/sphingomyelinase activity on vesicles containing coexisting ordered-disordered and gel-fluid domains.
  Ibarguren, M., López, D. J., Montes, L. R., Sot, J., Vasil, A. I., Vasil, M. L., Goñi, F. M., Alonso, A.> ;J Lipid Res. 2011 Apr
• Multiple phospholipid substrates of phospholipase C/sphingomyelinase HR2 from Pseudomonas aeruginosa.
  López DJ, Collado MI, Ibarguren M, Vasil AI, Vasil ML, Goñi FM, Alonso A> ;Chem. Phys. Lipids. 2011-01-01
• Ceramide-enriched membrane domains in red blood cells and the mechanism of sphingomyelinase-induced hot-cold hemolysis.
  Montes, L. R., López, D. J., Sot, J., Bagatolli, L. A., Stonehouse, M. J., Vasil, M. L., Wu, B. X., Hannun, Y. A., Goñi, F. M., Alonso, A.> ;Biochemistry. 2008-10-28
• Alkanes are not innocuous vehicles for hydrophobic reagents in membrane studies.
  Urbina P, Alonso A, Contreras F, Goñi FM, López DJ, Montes L, Sot J> ;Chem. Phys. Lipids. 2006-02-01
• Effects of 15-oxa-32-vinyl-lanost-8-ene-3 beta,32 diol on the expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase and low density lipoprotein receptor in rat...
  Ness GC, Lopez D, Chambers CM, Zhao Z, Beach DL, Ko SS, Trzaskos JM> ;Arch. Biochem. Biophys.. 1998-09-15
• Effects of L-triiodothyronine and the thyromimetic L-94901 on serum lipoprotein levels and hepatic low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzym...
  Ness GC, Lopez D, Chambers CM, Newsome WP, Cornelius P, Long CA, Harwood HJ> ;Biochem. Pharmacol.. 1998-07-01
• Compensatory responses to inhibition of hepatic squalene synthase.
  Lopez D, Chambers CM, Keller RK, Ness GC> ;Arch. Biochem. Biophys.. 1998-03-15
• Atorvastatin action involves diminished recovery of hepatic HMG-CoA reductase activity.
  Ness GC, Chambers CM, Lopez D> ;J. Lipid Res.. 1998-01-01
• Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase unmask transcriptional regulation of hepatic low-density lipoprotein receptor gene expression by dietary ...
  Lopez D, Ness GC> ;Arch. Biochem. Biophys.. 1997-08-01
• 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors unmask cryptic regulatory mechanisms.
  Lopez D, Chambers CM, Ness GC> ;Arch. Biochem. Biophys.. 1997-07-01
• Increased expression of low-density lipoprotein receptors in a Smith-Lemli-Opitz infant with elevated bilirubin levels.
  Ness GC, Lopez D, Borrego O, Gilbert-Barness E> ;Am. J. Med. Genet.. 1997-01-31
• Inhibitors of cholesterol biosynthesis increase hepatic low-density lipoprotein receptor protein degradation.
  Ness GC, Zhao Z, Lopez D> ;Arch. Biochem. Biophys.. 1996-01-15
• Transcriptional regulation of rat hepatic low-density lipoprotein receptor and cholesterol 7 alpha hydroxylase by thyroid hormone.
  Ness GC, Lopez D> ;Arch. Biochem. Biophys.. 1995-11-10
• Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by sterols and nonsterols in rat liver.
  Ness GC, Eales S, Lopez D, Zhao Z> ;Arch. Biochem. Biophys.. 1994-02-01
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