Overview of Dr. Nanus
I am the Director of New York Presbyterian Hospital - Weill Cornell Medicine Healthcare Systems Cancer Program and the Associate Director for Clinical Services in the Meyer Cancer Center at Weill Cornell Medicine. I was Chief of the Division of Hematology and Medical Oncology at Weill Cornell Medical College – New York Presbyterian Hospital for a5 years from 2004-2019. I am also the Mark W. Pasmantier Professor of Hematology and Medical Oncology in Medicine and Professor of Medicine and Urology. I completed my clinical training in Medicine at Albert Einstein College of Medicine followed by a fellowship in Medical Oncology at Memorial Sloan Kettering Cancer Center, and research training at the Sloan Kettering Institute. I joined the faculty at Memorial Sloan Kettering Cancer Center in 1989 as a physician scientist and was recruited to the full-time faculty of Weill Cornell Medical College in 1998. My clinical focus is the treatment and care of patients with genitourinary (GU) cancers, and I am actively involved in clinical, translational and basic research in GU malignancies, serving as principle or co-investigator on a variety of grants and clinical research trials that incorporate novel targeted therapies for patients, working closely with physicians and scientists.
Office
520 East 70th Street
Starr Pavilion, 3rd Floor
New York, NY 10021- Is this information wrong?
Education & Training
- Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 1985 - 1989
- Jacobi Medical Center/Albert Einstein College of MedicineResidency, Internal Medicine, 1983 - 1985
- University of Wisconsin Hospitals and ClinicsInternship, Internal Medicine, 1982 - 1983
- Chicago Medical School at Rosalind Franklin University of Medicine and ScienceClass of 1982
- University of Illinois at Urbana-ChampaignB.S., 1974 - 1978
Certifications & Licensure
- NY State Medical License 1983 - 2025
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Member American Association of Physicians, 2005
- Top Doctors for Cancer Newsweek Magazine, 2015
- Top Ranked U.S. Executive National Council of American Executives, 2014
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Clinical Trials
- Tretinoin Plus Interferon Alfa in Treating Patients With Metastatic Kidney Cancer Start of enrollment: 1999 Jan 01
- Sorafenib, Gemcitabine, and Capecitabine in Treating Patients With Unresectable and/or Metastatic Kidney Cancer Start of enrollment: 2005 Jun 03
- Treatment With ATRA-IV and Depakote in Patients With Advanced Solid Tumor Malignancies Start of enrollment: 2003 Jul 01
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Publications & Presentations
PubMed
- The Impact of Circulating Tumor Cell HOXB13 RNA Detection in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC) Treated with Abiraterone or Enzalutamide.Park, J., Susan Halabi, Siyuan Guo, Joseph J Park, David M Nanus, Daniel J George, Emmanuel S Antonarakis, Daniel Costin Danila, Russell Zelig Szmulewitz, Donald P McD...> ;Clinical Cancer Research. 2024 Mar 15
- 7 citationsNDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma.Jaclyn M Kubala, Kristian B Laursen, Ryan Schreiner, Ryan M Williams, Johannes C van der Mijn, Michael J Crowley, Nigel P Mongan, David M Nanus, Daniel A Heller, Lorra...> ;Cancer Biology & Therapy. 2023 Dec 31
- Prostate-Specific Membrane Antigen-Targeting Alpha Emitter via Antibody Delivery for Metastatic Castration-Resistant Prostate Cancer: A Phase I Dose-Escalation Study o...Scott T Tagawa, Charlene Thomas, A Oliver Sartor, Michael Sun, Judith Stangl-Kremser, Mahelia Bissassar, Shankar Vallabhajosula, Jones T Nauseef, Cora N Sternberg, Ana...> ;Journal of Clinical Oncology. 2024 Mar 1
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Journal Articles
- Kidney cancer: novel targets in altered tumour metabolismMinton DR and Nanus DM, Nature Rev Urol, 1/1/2015
- CANCER Cancer therapies that are gone with the WntNanus DM and Giannakakou P, Science, 1/1/2015
- The tale of two hypoxia-inducible factors in renal cell carcinomaNanus DM and Gudas LJ, Eur Urol, 1/1/2015
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Books/Book Chapters
Lectures
- Taxanes: Novel Combinations and Clinical StatesChicago, IL - 1/29/2015
- Circulating Tumor Cells in the MicroenvironmentLawrence Livermore National Laboratory, CA - 1/27/2015
- Advances and clinical trial opportunities in immunotherapy for GU cancers.Las Vegas, NV - 1/13/2015
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Press Mentions
- How to Find Support When You Have Metastatic Kidney CancerApril 25th, 2023
- Department of Defense Awards Weill Cornell Medicine New Grant for Kidney Cancer ResearchSeptember 1st, 2022
- Cancers Leading Cause of Premature Death in Brooklyn: NY-Presbyterian PhysiciansAugust 7th, 2019
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Grant Support
- Phase II Trial Of 177lu-J591 In Metastatic, Androgen-Independent Prostate CancerNational Center For Research Resources2007
- Phase I Trial Of ATRA-IV &Depakote In PTS W/Advanced Solid Tumor MalignanciesNational Center For Research Resources2005–2006
- Modulation Of Retinoic Acid Action In Renal CancerNational Cancer Institute2001–2005
- Neutral Endopeptidase Inactivation In Advanced ProstateNational Cancer Institute1998–2005
- Phase I 111-Indium Radiolabeled MAB Huj591/ Metastatic Solid TumorsNational Center For Research Resources2004
- Chemoprevention Of Prostate Cancer With FinasterideNational Center For Research Resources2004
- Anti Tumor Therapies For Genioturinary MalignanciesNational Cancer Institute2000–2004
- Alpha Interferon Resistance In Renal CancerNational Cancer Institute1994–1996
- Analysis Of Alpha-Interferon Resistance In Renal CancerNational Cancer Institute1992–1993
Professional Memberships
- Member
Hospital Affiliations
- New York-Presbyterian HospitalNew York, New York
- New York-Presbyterian HospitalNew York, New York
- New York-Presbyterian HospitalNew York, New York
- NewYork-Presbyterian Brooklyn Methodist HospitalBrooklyn, New York
Insurance Accepted
- Aetna Choice POS II
Aetna HMO
BCBS Blue Card PPO
CIGNA HMO
CIGNA Open Access
CIGNA PPO
Empire BCBS HMO
Empire BCBS PPO
First Choice
First Health PPO
GHI PPO
Great West PPO
Health Net Oregon PPOHIP of New York - Select PPO
Humana ChoiceCare Network PPO
Medical Mutual of Ohio SuperMed Plus
Medical Mutual of Ohio SuperMed POS
Multiplan PHCS PPO
Multiplan PPO
MVP Healthcare PPO
Oxford Health Freedom
Oxford Health Liberty
Premera BCBS Heritage & Heritage Plus 1
Providence Health System Personal Option
United Healthcare - Direct Choice Plus POS
United Healthcare - Direct Options PPO - Please verify your coverage with the provider's office directly when scheduling an appointment
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