
David S Siegel MD PhD
Hematologic Oncology
Chief, Myeloma Division John Theurer Cancer Center, Hackensack University Medical Center. Founding Director, Institute for Multiple Myeloma. Center for Discovery and Innovation
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92 2nd StHackensack, NJ 07601
Phone+1 551-996-8704
Fax+1 551-996-0582
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Summary
- Dr. David Siegel is an oncology specialist, focusing on hematologic oncology, based in Hackensack, NJ. He completed his medical education and training at reputable institutions, including a fellowship at Memorial Sloan Kettering Cancer Center. Dr. Siegel holds several prominent positions, including Chief of the Myeloma Division at Hackensack Meridian Health and Professor of Medicine at MedStar Georgetown University Hospital. He has extensive experience with conditions such as amyloidosis and myelofibrosis. Dr. Siegel has contributed significantly to the field through his research on multiple myeloma and has been involved in various clinical trials. His work has been published in well-regarded journals such as Leukemia & Lymphoma and Nature Genetics.
Education & Training
Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 1989 - 1992
NYU Grossman School of MedicineResidency, Internal Medicine, 1987 - 1989
NYU Grossman School of MedicineInternship, Internal Medicine, 1986 - 1987
New York University School of MedicineClass of 1986
New York UniversityPhD, 1985
Certifications & Licensure
NH State Medical License 2024 - 2028
NY State Medical License 1987 - 2028
OH State Medical License 2024 - 2028
AZ State Medical License 2024 - 2027
CO State Medical License 2024 - 2027
CT State Medical License 2024 - 2027
DE State Medical License 2024 - 2027
American Board of Internal Medicine Internal Medicine- Join now to see all
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2013, 2015-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2013, 2015-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2013, 2015-2017
Clinical Trials
- Safety Study of IPI-504 in Patients With Relapsed and Relapsed Refractory Multiple Myeloma
- High-Dose Interferon Alfa in Treating Patients With Stage II or StageIII Melanoma
- Lenalidomide and Low-Dose Dexamethasone in Patients With Previously Treated Multiple Myeloma and Kidney Dysfunction Start of enrollment: 2009 Jan 21
Publications & Presentations
PubMed
- Combined Immune Checkpoint Inhibitors and Radiation Therapy in Patients with Multiple Myeloma and Extramedullary Medullary Disease: A Real-World Retrospective Analysis.Lili Zhang, Ayrton Bangolo, Behzad Amoozgar, Sarvarinder Gill, Jiahe Zhao
Cancers. 2026-06-19 - Salvage Therapy in Multiple Myeloma With Prior T-Cell Engager Exposure: Talquetamab, Elranatamab or Teclistamab in Combination With Pomalidomide.James Di Palma-Grisi, David Vesole, David Siegel, Noa Biran, Pooja Phull
European Journal of Haematology. 2026-06-01 - Consolidation Therapy with Checkpoint Inhibitors After Autologous Hematopoietic Cell Transplantation in Patients with High-Risk Multiple Myeloma and Lymphoma.Lindsay Fogel, Patrick C Roney, Jaeil Ahn, Joshua Zenreich, Adolfo Aleman
Transplantation and Cellular Therapy. 2026-05-14
Journal Articles
- Carfilzomib vs Bortezomib in Patients with Multiple Myeloma and Renal Failure: A Subgroup Analysis of ENDEAVORRuben Niesvizky, David Siegel, Ralph Boccia, Blood
- Updated survival analyses after prolonged follow-up of the phase 2, multicenter CReST study of bortezomib in relapsed or refractory multiple myelomaJagannath S, Barlogie B, Berenson JR, Siegel DS, Irwin D, Richardson PG,Niesvizky R, Alexanian R, Limentani SA, Alsina M, esseltine DL, Anderson KC, Br J Haematol, 1/1/2014
- Phase I Trial of Anti-CS1 Monoclonal Antibody elotuzumab in Combination With Bortezomib in the Treatment of Relapsed/Refractory Multiple MyelomaJakubowiak AJ, Benson DM, Bensinger W, Siegel DS, Zimmerman TM, Mohrbacher A, Richardson PG, Afar De, Singhal AK, Anderson KC, J Clin Oncol, 1/30/2012
Books/Book Chapters
Lectures
- CAR T-Cell Therapy in Lymphoma, Myeloma, and Leukemia _ Clinical Updates and Innovations61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
- Efficacy and Safety of Carfilzomib and Dexamethasone in Lenalidomide Exposed and Refractory Multiple Myeloma Patients: Combined Analysis of Carfilzomib Trials2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Safety and Efficacy Data for Combined Checkpoint Inhibition with Ipilimumab (Ipi) and Nivolumab (Nivo) As Consolidation Following Autologous Stem Cell Transplantation ...2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Press Mentions
Immunogenomics Is on the Way UpAugust 12th, 2024
First Patient Dosed with Off-the-Shelf UCARTCS1 Product Candidate for Relapsed/Refractory Multiple MyelomaNovember 20th, 2019
FDA Approves Kyprolis (Carfilzomib) Once-Weekly Kd70 Regimen for Relapsed or Refractory Multiple MyelomaNovember 29th, 2011
Committees
- Working Group Member, International Waldenstrom's Macroglobulenemia Working Group 2011 - 2016
- Steering Committee, MMRF 2005 - 2016
- group Member, International Myeloma Working Group 2005 - 2016
Research History
- Chief, Myeloma Division12 current clinical trials2002 - 2016
Professional Memberships
- Member
- Fellow
- Member
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