DavidPaulSpeertMD

PubMed

• 32 citations
  Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes.
  Martina Sundqvist, Karin Christenson, Halla Björnsdottir, Veronica Osla, Anna Karlsson, Claes Dahlgren, David P. Speert, Anders Fasth, Kelly L. Brown, Johan Bylund> ;Frontiers in Immunology. 2017 Dec 21
• 41 citations
  A Prospective Cohort Study of Common Childhood Infections in South African HIV-exposed Uninfected and HIV-unexposed Infants.
  Amy L. Slogrove, Monika Esser, Mark F. Cotton, David P. Speert, Tobias R. Kollmann, Joel Singer, Julie A. Bettinger> ;The Pediatric Infectious Disease Journal. 2017 Feb 1
• 64 citations
  Long-Term Evolution of Burkholderia multivorans during a Chronic Cystic Fibrosis Infection Reveals Shifting Forces of Selection.
  Inês N. Silva, Pedro M. Santos, Mário Santos, James E. A. Zlosnik, David P. Speert, Sean W. Buskirk, Eric L. Bruger, Christopher M. Waters, Vaughn S. Cooper, Leonilde ...> ;Msystems. 2016 Jun 28
• 12 citations
  Activity of Tobramycin against Cystic Fibrosis Isolates of Burkholderia cepacia Complex Grown as Biofilms
  Sarah Kennedy, Trevor Beaudoin, Yvonne C. W. Yau, E. Caraher, James E. A. Zlosnik, David P. Speert, John J. LiPuma, Elizabeth Tullis, Valerie Waters> ;Antimicrobial Agents and Chemotherapy. 2016 Jan 1
• 5 citations
  Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia.
  Slade A. Loutet, Omar M. El-Halfawy, Agatha N. Jassem, José María Sánchez López, Antonio Fernández Medarde, David P. Speert, Julian Davies, Miguel A. Valvano> ;International Journal of Antimicrobial Agents. 2015 Oct 1
• 17 citations
  Surgical Masks Reduce Airborne Spread of Pseudomonas aeruginosa in Colonized Patients with Cystic Fibrosis
  Koen Vanden Driessche, Niel Hens, Peter Tilley, Bradley S. Quon, Mark A. Chilvers, Ronald de Groot, Mark F. Cotton, Ben J. Marais, David P. Speert, James E. A. Zlosnik> ;American Journal of Respiratory and Critical Care Medicine. 2015 Oct 1
• 7 citations
  Brain Abscesses Due to Aspergillus nidulans Infection During Induction Chemotherapy for Acute Lymphoblastic Leukemia.
  Manish Sadarangani, Melissa Harvey, Allison McDonald, David P. Speert, David Dix> ;Journal of Pediatric Hematology/oncology. 2015 Aug 1
• 38 citations
  Randomized controlled trial of biofilm antimicrobial susceptibility testing in cystic fibrosis patients.
  Yvonne C. W. Yau, Felix Ratjen, Elizabeth Tullis, Pearce G. Wilcox, Andreas Freitag, Mark A. Chilvers, Hartmut Grasemann, James E. A. Zlosnik, David P. Speert, Mary Co...> ;Journal of Cystic Fibrosis. 2015 Mar 1
• 66 citations
  Burkholderia species infections in patients with Cystic Fibrosis in British Columbia, Canada. 30 Years' experience
  James E. A. Zlosnik, Guohai Zhou, Rollin Brant, Deborah A. Henry, Trevor J. Hird, Eshwar Mahenthiralingam, Mark A. Chilvers, Pearce G. Wilcox, David P. Speert> ;Annals of the American Thoracic Society. 2015 Jan 30
• 17 citations
  In Vitro Efficacy of High-Dose Tobramycin against Burkholderia cepacia Complex and Stenotrophomonas maltophilia Isolates from Cystic Fibrosis Patients
  Anina Ratjen, Yvonne C. W. Yau, Jillian Wettlaufer, Larissa M. Matukas, James E. A. Zlosnik, David P. Speert, John J. LiPuma, Elizabeth Tullis, Valerie Waters> ;Antimicrobial Agents and Chemotherapy. 2015 Jan 1
• 40 citations
  Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients
  Cesar de la Fuente-Nunez, Sarah C. Mansour, Zhejun Wang, Lucy Jiang, Elena B. M. Breidenstein, Melissa Elliott, Fany Reffuveille, David P. Speert, Shauna L. Reckseidle...> ;Antibiotics. 2014 Oct 20
• 28 citations
  Single-Cell Analysis of Innate Cytokine Responses to Pattern Recognition Receptor Stimulation in Children across Four Continents
  Kinga K. Smolen, Bing Cai, Laura Gelinas, Edgardo S. Fortuno, Martin Larsen, David P. Speert, Mustapha Chamekh, Philip J. Cooper, Monika Esser, Arnaud Marchant, Tobias...> ;Journal of Immunology. 2014 Sep 15
• 18 citations
  Swimming Motility in a Longitudinal Collection of Clinical Isolates of Burkholderia cepacia Complex Bacteria from People with Cystic Fibrosis
  James E. A. Zlosnik, Paul Y. B. Mori, Derek To, James Leung, Trevor J. Hird, David P. Speert> ;Plos One. 2014 Sep 9
• 57 citations
  Altered innate immune development in HIV-exposed uninfected infants.
  Brian A. Reikie, R Adams, Aleksandra Leligdowicz, Kevin Ho, Shalena Naidoo, Candice E. Ruck, Corena de Beer, Wolfgang Preiser, Mark F. Cotton, David P. Speert, Monika ...> ;Journal of Acquired Immune Deficiency Syndromes. 2014 Jul 1
• 24 citations
  Fosmidomycin decreases membrane hopanoids and potentiates the effects of colistin on Burkholderia multivorans clinical isolates.
  Rebecca J. Malott, Chia-Hung Wu, Tracy D. Lee, Trevor J. Hird, Nathan F. Dalleska, James E. A. Zlosnik, Dianne K. Newman, David P. Speert> ;Antimicrobial Agents and Chemotherapy. 2014 Sep 1
• 43 citations
  Pattern recognition receptor-mediated cytokine response in infants across 4 continents.
  Kinga K. Smolen, Candice E. Ruck, Edgardo S. Fortuno, Kevin Ho, Pedro P. Dimitriu, William W. Mohn, David P. Speert, Philip J. Cooper, Monika Esser, Tessa Goetghebuer,...> ;The Journal of Allergy and Clinical Immunology. 2014 Mar 1
• 11 citations
  Investigation of aminoglycoside resistance inducing conditions and a putative AmrAB-OprM efflux system in Burkholderia vietnamiensis.
  Agatha N. Jassem, Connor M. Forbes, David P. Speert> ;Annals of Clinical Microbiology and Antimicrobials. 2014 Jan 6
• 29 citations
  Pseudomonas aeruginosa enhances production of a non-alginate exopolysaccharide during long-term colonization of the cystic fibrosis lung.
  Holly K. Huse, Taejoon Kwon, James E. A. Zlosnik, David P. Speert, Edward M. Marcotte, Marvin Whiteley> ;Plos One. 2013 Dec 6
• 2 citations
  Total protein extraction and 2-D gel electrophoresis methods for Burkholderia species.
  Billie Velapatiño, James E. A. Zlosnik, Trevor J. Hird, David P. Speert> ;Journal of Visualized Experiments. 2013 Oct 15
• 14 citations
  Recurrent subacute post-viral onset of ataxia associated with a PRF1 mutation.
  Cristina Dias, Allison McDonald, Murat Sincan, Rosemarie Rupps, Thomas C. Markello, Ramona Salvarinova, Rui Santos, Kamal Menghrajani, Chidi Ahaghotu, Darren Sutherlan...> ;European Journal of Human Genetics. 2013 Feb 27
• 63 citations
  Metabolic adaptations of Pseudomonas aeruginosa during cystic fibrosis chronic lung infections
  Volker Behrends, Ben Ryall, James E. A. Zlosnik, D. P. Speert, Jake G. Bundy, Huw D. Williams> ;Environmental Microbiology. 2013 Feb 1
• 54 citations
  Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of life
  Brian A. Reikie, Shalena Naidoo, Candice E. Ruck, Amy L. Slogrove, Corena de Beer, Heleen la Grange, R Adams, Kevin Ho, Kinga K. Smolen, David P. Speert, Mark F. Cotto...> ;Clinical and Vaccine Immunology. 2013 Jan 1
• 116 citations
  HIV-exposed uninfected infants are at increased risk for severe infections in the first year of life.
  Amy L. Slogrove, Brian A. Reikie, Shalena Naidoo, Corena de Beer, Kevin Ho, Mark F. Cotton, Julie A. Bettinger, David P. Speert, Monika Esser, Tobias R. Kollmann> ;Journal of Tropical Pediatrics. 2012 Dec 1
• 30 citations
  Ontogeny of Toll-Like Receptor Mediated Cytokine Responses of South African Infants throughout the First Year of Life
  Brian A. Reikie, R Adams, Candice E. Ruck, Kevin Ho, Aleksandra Leligdowicz, Santoshan Pillay, Shalena Naidoo, Edgardo S. Fortuno, Corena de Beer, Wolfgang Preiser, Ma...> ;Plos One. 2012 Sep 13
• 6 citations
  Serum Susceptibility in Clinical Isolates of Burkholderia Cepacia Complex Bacteria: Development of a Growth-Based Assay for High Throughput Determination
  James E. A. Zlosnik, L. Cynthia Gunaratnam, David P. Speert> ;Frontiers in Cellular and Infection Microbiology. 2012 May 28
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