David L Wirta MD

Oculo-Plastic & Orbital Reconstructive Surgery

Pres./CEO, Eye Research Foundation

520 Superior AveSte 235Newport Beach, CA 92663
Phone+1 949-650-1863
Fax+1 949-650-4359

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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical Center/UCLA Stein and Doheny Eye InstitutesResidency, Ophthalmology, 1994 - 1997
Los Angeles County-Harbor-UCLA Medical CenterInternship, Transitional Year, 1993 - 1994
David Geffen School of Medicine at UCLAClass of 1993

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Certifications & Licensure

OR State Medical License 1997 - Present
CA State Medical License 1995 - 2026
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

Top Doctors:LA Area Castle Connolly, 2013
Top Doctors:San Diego Area Castle Connolly, 2013
Top Doctors:Southern California Castle Connolly, 2012

Clinical Trials

Acute Tear Production Following Single Use of the Oculeve Intranasal Neurostimulator Start of enrollment: 2016 Jun 01
Completed
Not Applicable
Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye Disease Start of enrollment: 2016 Jun 01
Completed
Phase 3
Single-dose Study of ANX007 in Participants With Primary Open-angle Glaucoma Start of enrollment: 2018 Mar 23
Completed
Phase 1

Publications & Presentations

PubMed

7 citations
Acoltremon Ophthalmic Solution 0.003% for Signs and Symptoms of Dry Eye Disease: Results of Phase 3 Pivotal COMET-2 and COMET-3 Studies.
Guruprasad R Pattar, David Wirta, Gary Jerkins, James Paauw, Eugene B McLaurin
Ophthalmology. 2026-05-01
Safety and Efficacy of AGN-241622 for Presbyopia: Results From a First-in-Human, Phase 1/2, Randomized, Vehicle-Controlled Study.
Sherif M El-Harazi, James H Peace, Ashley Nguyen, Jiang Yuan, Susan Lee
Journal of Ocular Pharmacology and Therapeutics. 2026-02-28
1 citations
Safety and Efficacy of a Preservative-Free Bimatoprost 0.01% Ophthalmic Gel: Results From a Phase III Controlled Trial.
Eydie Miller-Ellis, James H Peace, Douglas G Day, Sherif M El-Harazi, Sylvie Nissle
Journal of Glaucoma. 2025-11-01

Journal Articles

Association of Oxymetazoline Hydrochloride, 0.1%, Solution Administration with Visual Field in Acquired Ptosis
Charles B Slonim, Michael S Korenfeld, Robert Smyth-Medina, David L Wirta, JAMA Ophthalmology

Press Mentions

Dry Eye Therapy with TRPM8 Agonist May Lead to Meaningful Long-Term ImprovementOctober 24th, 2025
Alcon Showcases Five Innovations Across Multiple Specialty Areas at ASCRS 2025April 17th, 2025
Understanding Meibomian Gland Dysfunction as a Driver for Dry Eye DiseaseFebruary 14th, 2023