DeepaBhojwaniMD

PubMed

• Nivolumab Plus 5-Azacitidine in Pediatric Relapsed/Refractory Acute Myeloid Leukemia (AML): Phase I/II Trial Results from the Therapeutic Advances in Childhood Leukemi...
  Verma, A., Chi, Y., Malvar, J., Lamble, A., Chaudhury, S., Agarwal, A., Li, H., Liang, G., Leong, R., Brown, P., Kaplan, J., Schafer, E., Slone, T., Pauly, M., Chang, ...> ;Cancers. 2024 Jan 24
• Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations.
  Maillard, M., Nishii, R., Yang, W., Hoshitsuki, K., Chepyala, D., Lee, S., Nguyen, J., Relling, M., Crews, K., Leggas, M., Singh, M., Suang, J., Yeoh, A., Jeha, S., In...> ;Journal of the National Cancer Institute. 2024 Jan 16
• 1 citations
  B-cell acute lymphoblastic leukemia and juvenile xanthogranuloma in a patient withthrombocytopenia and leukemia predisposition syndrome: novel clinical presentation an...
  Haley Newman, Suzanne P MacFarland, Garrett M Brodeur, Timothy Olson, Deepa Bhojwani, Jamie Stokke, Alexandra E Kovach, Mary Egan Clark, Minjie Luo, Marilyn Li, Amish ...> ;Haematologica. 2023 Nov 30
• Developing Therapy for Every Kid With Cancer - Summary of a Scientific Session at the 2023 ASCPT Meeting.
  Jason N Moore, Olivia Campagne, Deepa Bhojwani, Dean Crowe, Clinton F Stewart> ;Clinical Pharmacology and Therapeutics. 2024 Feb 1
• 1 citations
  Transcriptome Sequencing Allows Comprehensive Genomic Characterization of Pediatric B-Acute Lymphoblastic Leukemia in an Academic Clinical Laboratory.
  Zunsong Hu, Alexandra E Kovach, Dejerianne Ostrow, Andrew Doan, Jianling Ji, Ryan J Schmidt, Zhaohui Gu, Deepa Bhojwani, Gordana Raca, Venkata Yellapantula> ;The Journal of Molecular Diagnostics. 2024 Jan 1
• Outcomes in Children, Adolescents, and Young Adults With Down Syndrome and ALL: A Report From the Children's Oncology Group.
  Karen R Rabin, Meenakshi Devidas, Zhiguo Chen, Lingyun Ji, John Kairalla, Johann K Hitzler, Jun J Yang, Andrew J Carroll, Nyla A Heerema, Michael J Borowitz, Brent L W...> ;Journal of Clinical Oncology. 2024 Jan 10
• 1 citations
  INSPIRED Symposium Part 4A: Access to CAR T Cell Therapy in Unique Populations with B Cell Acute Lymphoblastic Leukemia.
  Lena E Winestone, Deepa Bhojwani, Sara Ghorashian, Lori Muffly, Allison Barz Leahy, Karen Chao, Angela Steineck, Claudia Rössig, Adam Lamble, Shannon L Maude, Regina M...> ;Transplantation and Cellular Therapy. 2024 Jan 1
• 2 citations
  Children's Oncology Group blueprint for research: Acute lymphoblastic leukemia.
  Elizabeth A Raetz, Deepa Bhojwani, Meenakshi Devidas, Lia Gore, Karen R Rabin, Sarah K Tasian, David T Teachey, Mignon L Loh> ;Pediatric Blood & Cancer. 2023 Sep 1
• Asparaginase toxicity in Hispanic adult and pediatric patients with acute lymphoblastic leukemia: current understanding.
  Amani Alqahtani, Diala Alhousari, Amir Ali, George Yaghmour, Etan Orgel, Emily Curran, Wendy Stock, Deepa Bhojwani, Houda Alachkar> ;Expert Opinion on Drug Metabolism & Toxicology. 2023 Jul 6
• 2 citations
  Chimeric Antigen Receptor T Cells as Salvage Therapy for Post-Chimeric Antigen Receptor T Cell Failure.
  Elizabeth M Holland, Bonnie Yates, Seth M Steinberg, Constance M Yuan, Hao-Wei Wang, Colleen Annesley, Haneen Shalabi, David Stroncek, Terry J Fry, Joerg Krueger, Elad...> ;Transplantation and Cellular Therapy. 2023 Sep 1
• Efficacy and safety of FLAG-IDA as front-line therapy in de novo paediatric acute myeloid leukaemia population.
  Andrew Doan, Holly K T Huang, Ari J Hadar, Jemily Malvar, Teresa Rushing, Gordana Raca, Alexandra E Kovach, David R Freyer, Chintan Parekh, Jamie Stokke, Leila C Posch...> ;British Journal of Haematology. 2023 Jul 1
• 4 citations
  Ibrutinib plus RICE or RVICI for relapsed/refractory mature B-cell non-Hodgkin lymphoma in children and young adults: SPARKLE trial.
  G A Amos Burke, Luciana Vinti, Edita Kabickova, Auke Beishuizen, Nurdan Tacyildiz, Anne Uyttebroeck, Hyoung Jin Kang, Flavio Luisi, Véronique Minard-Colin, Birgit Burk...> ;Blood Advances. 2023 Feb 28
• 48 citations
  Preinfusion factors impacting relapse immunophenotype following CD19 CAR T cells.
  Adam J Lamble, Regina M Myers, Agne Taraseviciute, Samuel John, Bonnie Yates, Seth M Steinberg, Jennifer Sheppard, Alexandra E Kovach, Brent Wood, Michael J Borowitz, ...> ;Blood Advances. 2023 Feb 28
• 1 citations
  Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.
  Heather A Ogana, Samantha Hurwitz, Chih-Lin Hsieh, Huimin Geng, Markus Müschen, Deepa Bhojwani, Mark A Wolf, James Larocque, Michael R Lieber, Yong Mi Kim> ;Frontiers in Cell and Developmental Biology. 2023 Jan 1
• 5 citations
  Real-world experience in treating pediatric relapsed/refractory or therapy-related myeloid malignancies with decitabine, vorinostat, and FLAG therapy based on a phase ...
  Eric S Schafer, Karen Chao, Alexandra M Stevens, Eunji Jo, Susan G Hilsenbeck, Nathan P Gossai, Andrew Doan, Susan I Colace, Terri Guinipero, Daniel Otterson, Joel A K...> ;Pediatric Blood & Cancer. 2022 Oct 1
• 6 citations
  Low rate of subsequent malignant neoplasms after CD19 CAR T-cell therapy.
  Emily M Hsieh, Regina M Myers, Bonnie Yates, Colleen Annesley, Samuel John, Agne Taraseviciute, Seth M Steinberg, Jennifer Sheppard, Perry Chung, Lee Chen, Daniel W Le...> ;Blood Advances. 2022 Sep 13
• 3 citations
  Characterization of PAX5 intragenic tandem multiplication in pediatric B-lymphoblastic leukemia by optical genome mapping.
  Jeffrey Jean, Alexandra E Kovach, Andrew Doan, Matthew Oberley, Jianling Ji, Ryan J Schmidt, Jaclyn A Biegel, Deepa Bhojwani, Gordana Raca> ;Blood Advances. 2022 Jun 14
• 3 citations
  Hispanic ethnicity and the rs4880 variant in SOD2 are associated with elevated liver enzymes and bilirubin levels in children receiving asparaginase-containing chemoth...
  Sharon Wu, Mengxi Wang, Amani Alqahtani, Mimi Lou, Wendy Stock, Deepa Bhojwani, Houda Alachkar> ;Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2022 Jun 1
• 19 citations
  Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) c...
  Pommert, L., Schafer, E., Malvar, J., Gossai, N., Florendo, E., Pulakanti, K., Heimbruch, K., Stelloh, C., Chi, Y., Sposto, R., Rao, S., Huynh, V., Brown, P., Chang, B...> ;American Journal of Hematology. 2022 May 1
• 33 citations
  Phase II Trial of Inotuzumab Ozogamicin in Children and Adolescents With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia: Children's Oncology Group Protocol...
  Maureen M O'Brien, Lingyun Ji, Nirali N Shah, Susan R Rheingold, Deepa Bhojwani, Constance M Yuan, Xinxin Xu, Joanna S Yi, Andrew C Harris, Patrick A Brown, Michael J ...> ;Journal of Clinical Oncology. 2022 Mar 20
• 1 citations
  Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis.
  Alexandra E Kovach, Elena Zerkalenkova, Ludmila Zemtsova, Aleksandra Borkovskaya, Marina Gaskova, Marat Kazanov, Alexander Popov, Liudmila Baidun, Michael Maschan, Ale...> ;Cancer Genetics. 2022 Jan 1
• 3 citations
  Managing therapy-associated neurotoxicity in children with ALL.
  Deepa Bhojwani, Ravi Bansal, Alan S Wayne> ;Hematology. American Society of Hematology. Education Program. 2021 Dec 10
• 1 citations
  Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia
  Yongsheng Ruan, Hye Na Kim, Heather Ogana, Zesheng Wan, Samantha Hurwitz, Cydney Nichols, Nour Abdel-Azim, Ariana Coba, Seyoung Seo, Yong-Hwee Eddie Loh, Eun Ji Gang, ...> ;Frontiers in Oncology. 2021 Dec 1
• 7 citations
  In vitro and in vivo effects of AVA4746, a novel competitive antagonist of the ligand binding of VLA‑4, in B‑cell acute lymphoblastic leukemia
  Yongsheng Ruan, Hye Na Kim, Heather Ogana, Eun Ji Gang, Shuangyue Li, Hsiao-Chuan Liu, Deepa Bhojwani, Alan S. Wayne, Mo Yang, Yong-Mi Kim> ;Experimental and Therapeutic Medicine. 2021 Nov 15
• 84 citations
  Blinatumomab Nonresponse and High-Disease Burden Are Associated With Inferior Outcomes After CD19-CAR for B-ALL.
  Regina M. Myers, Agne Taraseviciute, Seth M. Steinberg, Adam J. Lamble, Jennifer Sheppard, Bonnie Yates, Alexandra E. Kovach, Brent L. Wood, Michael J. Borowitz, Marya...> ;Journal of Clinical Oncology. 2021 Nov 12
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Journal Articles

• Inotuzumab Ozogamicin in Pediatric Patients with relapsed/refractory Acute Lymphoblastic Leukemia  
  Deepa Bhojwani, Constance Yuan, Jennifer L McNeer, Mignon L Loh, Vilmarie Rodriguez, Susan R Rheingold, Elizabeth A Raetz, Nature

Abstracts/Posters

• Phase 1 Study of Decitabine and Vorinostat Followed By Fludarabine, Cytarabine and G-CSF (FLAG) in Children, Adolescents and Young Adults with Relapsed/Refractory AML:...
  Deepa Bhojwani, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy
  Deepa Bhojwani, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• A Phase 2 Trial of Inotuzumab Ozogamicin (InO) in Children and Young Adults with Relapsed or Refractory (R/R) CD22+ B-Acute Lymphoblastic Leukemia (B-ALL): Results fro...
  Deepa Bhojwani, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Targeting of Integrin _4/VCAM-1 with AVA4746 Modulates the Redox-Status and Metabolism in ALL and Angiogenesis
  Deepa Bhojwani, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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